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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane protein proteolysis
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Accession:GO:0033619 term browser browse the term
Definition:The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.


show annotations for term's descendants           Sort by:
membrane protein proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 involved_in ISO
IEA 		(PMID:22354088)
GO_REF:0000107 		RGD
Ensembl		 PMID:22354088 GO_REF:0000107 NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit involved_in ISO
IEA 		(PMID:22354088)
GO_REF:0000107 		RGD
Ensembl		 PMID:22354088 GO_REF:0000107 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693 		JBrowse link
G Ctsh cathepsin H involved_in ISO
IEA
ISS 		(PMID:14766755)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:14766755 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within ISO
IEA 		(PMID:34380733)
GO_REF:0000107 		RGD
Ensembl		 PMID:34380733 GO_REF:0000107 NCBI chr14:35,108,328...35,154,578
Ensembl chr14:34,754,289...34,800,814 		JBrowse link
G Hm13 histocompatibility minor 13 involved_in ISO
IEA
IBA 		(PMID:14741365)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:14741365 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G Mcts2 MCTS family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:161,623,597...161,624,375 JBrowse link
G Napsa napsin A aspartic peptidase involved_in ISO
IEA 		(PMID:14766755)
GO_REF:0000107 		RGD
Ensembl		 PMID:14766755 GO_REF:0000107 NCBI chr 1:95,064,726...95,077,101
Ensembl chr 1:95,064,900...95,077,094 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISO
IEA 		(PMID:22354088)
GO_REF:0000107 		RGD
Ensembl		 PMID:22354088 GO_REF:0000107 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:21357690) RGD PMID:21357690 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISO
ISS 		(PMID:18953687), (PMID:22624035) RGD PMID:18953687 PMID:22624035 PMID:18953687 PMID:22624035 RGD:8554435, RGD:8553377 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Sppl2a signal peptide peptidase-like 2A involved_in ISO
IEA
IBA 		(PMID:2313285)
GO_REF:0000107
(PMID:33239420)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:2313285 PMID:33239420 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:134,602,684...134,646,752
Ensembl chr 3:114,151,069...114,193,264 		JBrowse link
G Sppl2b signal peptide peptidase-like 2B involved_in ISS
IEA
IBA
ISO 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:2313285) 		UniProt
Ensembl
GO_Central
RGD		 PMID:2313285 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:9,494,593...9,507,317
Ensembl chr 7:8,843,918...8,856,608 		JBrowse link
G Sppl2c signal peptide peptidase like 2C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:89,595,265...89,597,470
Ensembl chr10:89,095,261...89,098,580 		JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in ISO
IBA 		(PMID:2313285)
GO_REF:0000033 		RGD
GO_Central		 PMID:2313285 GO_REF:0000033 NCBI chr12:47,176,317...47,260,756
Ensembl chr12:41,515,640...41,600,126 		JBrowse link
G Tmprss6 transmembrane serine protease 6 involved_in ISO
IEA 		(PMID:25156943)
GO_REF:0000107 		RGD
Ensembl		 PMID:25156943 GO_REF:0000107 NCBI chr 7:109,991,008...110,021,626
Ensembl chr 7:109,985,931...110,021,624 		JBrowse link
constitutive protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 involved_in ISO
IEA 		(PMID:12714508)
GO_REF:0000107 		RGD
Ensembl		 PMID:12714508 GO_REF:0000107 NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000107
(PMID:17245433), (PMID:29325091), (PMID:29430990), (PMID:30639848)
GO_REF:0000033
(PMID:12714508), (PMID:17557115), (PMID:17965014), (PMID:18355445), (PMID:18373975), (PMID:18419754), (PMID:18676862), (PMID:19114711), (PMID:20711474), (PMID:24990881), (PMID:28164773), (PMID:28855301), (PMID:29430990), (PMID:31792032), (PMID:34739841)
(PMID:18355449) 		UniProt
Ensembl
RGD
GO_Central		 PMID:12714508 PMID:17245433 PMID:17557115 PMID:17965014 PMID:18355445 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in
acts_upstream_of_or_within 		TAS
ISO
IEA
IBA
ISS
IMP 		(PMID:12743035), (PMID:14625290), (PMID:15691827), (PMID:16034137), (PMID:17010968), (PMID:17786981), (PMID:18355445), (PMID:18373975), (PMID:18676862), (PMID:21170088), (PMID:24337742), (PMID:24990881), (PMID:36476876), (PMID:9034190), (PMID:9034191), (PMID:9574564)
GO_REF:0000107
(PMID:15691827), (PMID:17245433), (PMID:9034190)
(PMID:26651291)
GO_REF:0000033
GO_REF:0000024
(PMID:9034191) 		RGD
Ensembl
GO_Central
UniProt		 PMID:9034190 PMID:9034191 PMID:9574564 PMID:12743035 PMID:14625290 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1559178, RGD:2317978 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adam19 ADAM metallopeptidase domain 19 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:3620562 (PMID:11116142), (PMID:14975714) 		GO_Central
RGD		 PMID:11116142 PMID:14975714 GO_REF:0000033 NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,491,405...30,583,105 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in
acts_upstream_of_or_within 		ISO
IBA 		(PMID:12054541)
(PMID:19273593), (PMID:22480688)
GO_REF:0000033
(PMID:22480688), (PMID:9920899)
(PMID:23437250) 		RGD
GO_Central		 PMID:9920899 PMID:12054541 PMID:19273593 PMID:22480688 PMID:23437250 GO_REF:0000033 NCBI chr16:73,725,186...73,804,284
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit involved_in ISO (PMID:15274632) RGD PMID:15274632 NCBI chr 2:186,123,023...186,130,886
Ensembl chr 2:183,438,434...183,441,955 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit acts_upstream_of_or_within ISO MGI:1915568 (PMID:18626010) RGD PMID:18626010 NCBI chr 8:76,310,380...76,334,146
Ensembl chr 8:67,429,198...67,450,243 		JBrowse link
G Bace1 beta-secretase 1 involved_in ISO
IEA
IBA 		(PMID:18353773)
GO_REF:0000107
(PMID:29325091)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:18353773 PMID:29325091 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bace2 beta-secretase 2 involved_in ISS
IBA
ISO 		GO_REF:0000024
GO_REF:0000033
(PMID:10591213), (PMID:21907142) 		UniProt
GO_Central
RGD		 PMID:10591213 PMID:21907142 GO_REF:0000024 GO_REF:0000033 NCBI chr11:50,176,852...50,258,948
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within ISO
IEA 		(PMID:34380733)
GO_REF:0000107 		RGD
Ensembl		 PMID:34380733 GO_REF:0000107 NCBI chr14:35,108,328...35,154,578
Ensembl chr14:34,754,289...34,800,814 		JBrowse link
G Dag1 dystroglycan 1 involved_in ISO
IEA 		(PMID:19946898)
GO_REF:0000107 		RGD
Ensembl		 PMID:19946898 GO_REF:0000107 NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 involved_in ISO
ISS 		(PMID:12748171)
GO_REF:0000024 		RGD
UniProt		 PMID:12748171 GO_REF:0000024 NCBI chr 2:5,666,337...5,705,256
Ensembl chr 2:3,931,904...3,972,447 		JBrowse link
G Hm13 histocompatibility minor 13 NOT|involved_in ISO (PMID:17965014) RGD PMID:17965014 NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 acts_upstream_of ISO
IEA 		(PMID:26651291)
GO_REF:0000107 		RGD
Ensembl		 PMID:26651291 GO_REF:0000107 NCBI chr 2:194,635,686...194,705,014
Ensembl chr 2:191,949,819...192,012,579 		JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO
IEA 		(PMID:23437250)
GO_REF:0000107 		RGD
Ensembl		 PMID:23437250 GO_REF:0000107 NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO
ISS 		(PMID:16186248)
GO_REF:0000024 		RGD
UniProt		 PMID:16186248 GO_REF:0000024 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Ncstn nicastrin involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15274632) 		UniProt
Ensembl
RGD		 PMID:15274632 GO_REF:0000024 GO_REF:0000107 NCBI chr13:87,062,827...87,078,839
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (PMID:17286969) RGD PMID:17286969 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Prkcq protein kinase C, theta involved_in IEA
ISO 		GO_REF:0000107
(PMID:9857183) 		Ensembl
RGD		 PMID:9857183 GO_REF:0000107 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Prtn3 proteinase 3 involved_in ISO (PMID:23202369) RGD PMID:23202369 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944 		JBrowse link
G Psen1 presenilin 1 involved_in IMP
IEA
IBA
ISS
ISO 		GO_REF:0000107
GO_REF:0000033
GO_REF:0000024
(PMID:15274632) 		Ensembl
GO_Central
UniProt
RGD		 PMID:15274632 PMID:17433308 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1626321 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 involved_in ISO
IEA
IBA 		(PMID:15274632)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:15274632 GO_REF:0000033 GO_REF:0000107 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Psenen presenilin enhancer gamma secretase subunit involved_in ISO
IEA 		(PMID:15274632)
GO_REF:0000107 		RGD
Ensembl		 PMID:15274632 GO_REF:0000107 NCBI chr 1:94,942,348...94,943,545
Ensembl chr 1:85,814,905...85,816,192 		JBrowse link
G Rbmx RNA binding motif protein, X-linked involved_in ISO (PMID:18445477) RGD PMID:18445477 NCBI chr  X:135,305,237...135,314,806
Ensembl chr  X:135,305,325...135,314,743 		JBrowse link
G Rbmxl1 Rbmx like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:46,312,176...46,315,802
Ensembl chr19:29,407,912...29,412,859 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a acts_upstream_of ISO
IEA 		(PMID:26651291)
GO_REF:0000107 		RGD
Ensembl		 PMID:26651291 GO_REF:0000107 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Sppl2a signal peptide peptidase-like 2A involved_in ISO
IEA 		(PMID:16829951), (PMID:17965014)
GO_REF:0000107 		RGD
Ensembl		 PMID:16829951 PMID:17965014 GO_REF:0000107 NCBI chr 3:134,602,684...134,646,752
Ensembl chr 3:114,151,069...114,193,264 		JBrowse link
G Sppl2b signal peptide peptidase-like 2B involved_in ISO
IEA
ISS 		(PMID:16829951), (PMID:17965014)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:16829951 PMID:17965014 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:9,494,593...9,507,317
Ensembl chr 7:8,843,918...8,856,608 		JBrowse link
G Sppl2c signal peptide peptidase like 2C NOT|involved_in ISO (PMID:17965014) RGD PMID:17965014 NCBI chr10:89,595,265...89,597,470
Ensembl chr10:89,095,261...89,098,580 		JBrowse link
G Sppl3 signal peptide peptidase like 3 NOT|involved_in ISO (PMID:16829952), (PMID:17965014) RGD PMID:16829952 PMID:17965014 NCBI chr12:47,176,317...47,260,756
Ensembl chr12:41,515,640...41,600,126 		JBrowse link
membrane protein intracellular domain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 acts_upstream_of_or_within ISO (PMID:23437250) RGD PMID:23437250 NCBI chr16:73,725,186...73,804,284
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit involved_in ISO (PMID:12297508), (PMID:15274632) RGD PMID:12297508 PMID:15274632 NCBI chr 2:186,123,023...186,130,886
Ensembl chr 2:183,438,434...183,441,955 		JBrowse link
G Hm13 histocompatibility minor 13 NOT|involved_in ISO (PMID:16829952) RGD PMID:16829952 NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q14703 (PMID:16417584) 		Ensembl
RGD		 PMID:16417584 GO_REF:0000107 NCBI chr19:64,470,245...64,521,438
Ensembl chr19:47,561,598...47,612,791 		JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 involved_in ISO
IEA 		UniProtKB:O54862 (PMID:11163209)
GO_REF:0000107 		RGD
Ensembl		 PMID:11163209 GO_REF:0000107 NCBI chr  X:37,410,914...37,461,130
Ensembl chr  X:37,410,811...37,464,430 		JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO
IEA 		(PMID:23437250)
GO_REF:0000107 		RGD
Ensembl		 PMID:23437250 GO_REF:0000107 NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Ncstn nicastrin involved_in ISO
IEA 		(PMID:15274632)
GO_REF:0000107 		RGD
Ensembl		 PMID:15274632 GO_REF:0000107 NCBI chr13:87,062,827...87,078,839
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G Psenen presenilin enhancer gamma secretase subunit involved_in ISO
IEA 		(PMID:15274632)
GO_REF:0000107 		RGD
Ensembl		 PMID:15274632 GO_REF:0000107 NCBI chr 1:94,942,348...94,943,545
Ensembl chr 1:85,814,905...85,816,192 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:22795130) 		UniProt
Ensembl
RGD		 PMID:22795130 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Sppl2a signal peptide peptidase-like 2A involved_in ISO
IEA 		(PMID:16829951), (PMID:16829952), (PMID:17557115)
GO_REF:0000107 		RGD
Ensembl		 PMID:16829951 PMID:16829952 PMID:17557115 GO_REF:0000107 NCBI chr 3:134,602,684...134,646,752
Ensembl chr 3:114,151,069...114,193,264 		JBrowse link
G Sppl2b signal peptide peptidase-like 2B involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:16829951), (PMID:16829952), (PMID:19114711), (PMID:22194595) 		UniProt
Ensembl
RGD		 PMID:16829951 PMID:16829952 PMID:19114711 PMID:22194595 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:9,494,593...9,507,317
Ensembl chr 7:8,843,918...8,856,608 		JBrowse link
G Sppl2c signal peptide peptidase like 2C NOT|involved_in ISO (PMID:16829952)
(PMID:30733281) 		RGD PMID:16829952 PMID:30733281 NCBI chr10:89,595,265...89,597,470
Ensembl chr10:89,095,261...89,098,580 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
IEA
ISS 		(PMID:25310401)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:25310401 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Yy2 YY2 transcription factor involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:37,438,425...37,442,047
Ensembl chr  X:37,410,811...37,464,430 		JBrowse link
membrane protein proteolysis involved in retrograde protein transport, ER to cytosol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hm13 histocompatibility minor 13 involved_in ISO
IEA 		(PMID:25239945)
GO_REF:0000107 		RGD
Ensembl		 PMID:25239945 GO_REF:0000107 NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 involved_in ISO
IEA 		(PMID:22795130)
GO_REF:0000107 		RGD
Ensembl		 PMID:22795130 GO_REF:0000107 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 involved_in ISO
IEA
ISS 		(PMID:18383040)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:18383040 GO_REF:0000024 GO_REF:0000107 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 acts_upstream_of_or_within ISO
IEA 		(PMID:26651291)
GO_REF:0000107 		RGD
Ensembl		 PMID:26651291 GO_REF:0000107 NCBI chr 2:194,635,686...194,705,014
Ensembl chr 2:191,949,819...192,012,579 		JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 involved_in ISO (PMID:12207026) RGD PMID:12207026 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 involved_in ISO
IEA
IBA 		(PMID:12714508)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:12714508 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 involved_in ISO
IBA
IEA 		(PMID:18383040)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:18383040 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:149,978,667...149,985,350
Ensembl chr 4:148,304,490...148,312,558 		JBrowse link
positive regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO
IEA
IBA 		(PMID:15220135), (PMID:17548643)
GO_REF:0000107
(PMID:14761956)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:14761956 PMID:15220135 PMID:17548643 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:9857183) RGD PMID:9857183 NCBI chr16:73,725,186...73,804,284
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO
IEA 		(PMID:17655843)
GO_REF:0000107 		RGD
Ensembl		 PMID:17655843 GO_REF:0000107 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA 		UniProtKB:P05067-PRO_0000000092 (PMID:15950758), (PMID:25015123)
GO_REF:0000107 		RGD
Ensembl		 PMID:15950758 PMID:25015123 GO_REF:0000107 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:P02649 (PMID:25015123) RGD PMID:25015123 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:17720976)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:17720976 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:18373975) RGD PMID:18373975 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:18373975) RGD PMID:18373975 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Nrdc nardilysin convertase involved_in ISO
ISS
IEA 		(PMID:18355445)
(PMID:19935654)
GO_REF:0000024
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:18355445 PMID:19935654 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:123,755,807...123,818,910
Ensembl chr 5:123,755,806...123,818,595 		JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 involved_in ISO
IEA 		(PMID:15280379)
GO_REF:0000107 		RGD
Ensembl		 PMID:15280379 GO_REF:0000107 NCBI chr 3:77,227,187...77,235,820
Ensembl chr 3:77,222,710...77,235,811 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a acts_upstream_of_or_within ISO
IEA 		(PMID:26651291)
GO_REF:0000107 		RGD
Ensembl		 PMID:26651291 GO_REF:0000107 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Sh3d19 SH3 domain containing 19 involved_in ISO (PMID:15280379) RGD PMID:15280379 NCBI chr 2:171,356,244...171,516,042
Ensembl chr 2:171,356,251...171,515,561 		JBrowse link
G Snx33 sorting nexin 33 involved_in ISO
IEA 		(PMID:18353773), (PMID:18419754)
GO_REF:0000107 		RGD
Ensembl		 PMID:18353773 PMID:18419754 GO_REF:0000107 NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538 		JBrowse link
G Snx9 sorting nexin 9 involved_in ISO
IEA 		(PMID:18353773)
GO_REF:0000107 		RGD
Ensembl		 PMID:18353773 GO_REF:0000107 NCBI chr 1:48,827,061...48,915,215
Ensembl chr 1:46,423,553...46,509,036 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA 		(PMID:18373975)
GO_REF:0000107 		RGD
Ensembl		 PMID:18373975 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO
IBA 		(PMID:22480688)
GO_REF:0000033 		RGD
GO_Central		 PMID:22480688 GO_REF:0000033 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tspan15 tetraspanin 15 involved_in ISO
IEA 		(PMID:31792032), (PMID:34739841)
GO_REF:0000107 		RGD
Ensembl		 PMID:31792032 PMID:34739841 GO_REF:0000107 NCBI chr20:30,130,528...30,174,912
Ensembl chr20:30,130,530...30,174,930 		JBrowse link
G Tspan17 tetraspanin 17 involved_in IEA
ISO 		GO_REF:0000107
(PMID:28600292) 		Ensembl
RGD		 PMID:28600292 GO_REF:0000107 NCBI chr17:9,819,212...9,826,851
Ensembl chr17:9,819,202...9,826,834 		JBrowse link
G Tspan5 tetraspanin 5 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:28600292), (PMID:31792032) 		UniProt
Ensembl
RGD		 PMID:28600292 PMID:31792032 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          protein metabolic process 5185
            proteolysis 1709
              membrane protein proteolysis 65
                membrane protein ectodomain proteolysis + 52
                membrane protein intracellular domain proteolysis + 14
                membrane protein proteolysis involved in retrograde protein transport, ER to cytosol 2
paths to the root