Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:Leydig cell differentiation
go back to main search page
Accession:GO:0033327 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.


show annotations for term's descendants           Sort by:
Leydig cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amh anti-Mullerian hormone involved_in ISS
ISO		 GO_REF:0000024
(PMID:9435237)		 UniProt
RGD		 PMID:9435237 GO_REF:0000024 NCBI chr 7:9,557,451...9,559,867
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Ar androgen receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3717246 (PMID:19574395)		 Ensembl
RGD		 PMID:19574395 GO_REF:0000107 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Ccnd1 cyclin D1 IMP RGD PMID:17303663 RGD:2289137 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Dhh desert hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1095403|MGI:1934259 (PMID:12050120), (PMID:17495005) RGD PMID:12050120 PMID:17495005 NCBI chr 7:131,929,857...131,935,352
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 IEP RGD PMID:12810569 RGD:2302236 NCBI chr  X:24,568,551...24,571,012
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP RGD PMID:18502897 RGD:4781870 NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 IEP RGD PMID:18502897 RGD:4781870 NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Map7 microtubule-associated protein 7 acts_upstream_of_or_within ISO MGI:2148221 (PMID:10837026) RGD PMID:10837026 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 IEP RGD PMID:15149725 RGD:2302287 NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857494 (PMID:12399445)		 Ensembl
RGD		 PMID:12399445 GO_REF:0000107 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1346833|MGI:2159321 (PMID:11564714), (PMID:15829514)		 Ensembl
RGD		 PMID:11564714 PMID:15829514 GO_REF:0000107 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:31133074 RGD:408364990 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 acts_upstream_of_or_within ISO MGI:1352460 (PMID:15829514) RGD PMID:15829514 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2449440|MGI:3689423 (PMID:19056881)		 Ensembl
RGD		 PMID:19056881 GO_REF:0000107 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 acts_upstream_of_or_within ISO MGI:3526857 (PMID:19056881) RGD PMID:19056881 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156 		JBrowse link
G Sf1 splicing factor 1 acts_upstream_of_or_within ISO MGI:94891 (PMID:17495005) RGD PMID:17495005 NCBI chr 1:213,090,256...213,112,688
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3526851 (PMID:19056881)		 Ensembl
RGD		 PMID:19056881 GO_REF:0000107 NCBI chr20:29,590,652...29,637,064
Ensembl chr20:29,047,796...29,094,084 		JBrowse link
G Tmf1 TATA element modulatory factor 1 acts_upstream_of_or_within ISO MGI:4867392 (PMID:23000399) RGD PMID:23000399 NCBI chr 4:131,316,630...131,345,666
Ensembl chr 4:129,763,114...129,785,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    reproductive process 1970
      developmental process involved in reproduction 1262
        Leydig cell differentiation 21
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      anatomical structure development 6611
        multicellular organism development 5330
          system development 4612
            reproductive system development 444
              reproductive structure development 439
                gonad development 347
                  male gonad development 212
                    Leydig cell differentiation 21
paths to the root