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ONTOLOGY REPORT - ANNOTATIONS

Term:iron import into cell
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Accession:GO:0033212 term browser browse the term
Definition:The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
Synonyms:narrow_synonym: ferrous ion import;   ferrous iron import;   ferrous iron uptake
 related_synonym: iron assimilation
 alt_id: GO:0070627


show annotations for term's descendants           Sort by:
iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc11a2 solute carrier family 11 member 2 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:17109629)
GO_REF:0000107
MGI:1856400 (PMID:11739192) 		RGD
Ensembl		 PMID:11739192 PMID:17109629 GO_REF:0000107 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO
IEA 		(PMID:20682781)
GO_REF:0000107 		RGD
Ensembl		 PMID:20682781 GO_REF:0000107 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) RGD PMID:16609065 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
G Steap4 STEAP4 metalloreductase acts_upstream_of_or_within ISO
IEA 		(PMID:16609065)
GO_REF:0000107 		RGD
Ensembl		 PMID:16609065 GO_REF:0000107 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859 		JBrowse link
endocytic iron import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfr2 transferrin receptor 2 involved_in ISO
IBA 		UniProtKB:P02787|UniProtKB:Q07891 (PMID:18353247)
GO_REF:0000033 		RGD
GO_Central		 PMID:18353247 GO_REF:0000033 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591 		JBrowse link
heme import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slco2b1 solute carrier organic anion transporter family, member 2b1 acts_upstream_of_or_within ISO (PMID:35714613) RGD PMID:35714613 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in ISO
IEA
IDA 		(PMID:22898811)
GO_REF:0000107
(PMID:22898811), (PMID:30015240) 		RGD
Ensembl		 PMID:22898811 PMID:30015240 PMID:22898811 GO_REF:0000107, RGD:15090842 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129 		JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO
IEA 		(PMID:16609065)
GO_REF:0000107 		RGD
Ensembl		 PMID:16609065 GO_REF:0000107 NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO
IEA 		(PMID:20436681)
GO_REF:0000107 		RGD
Ensembl		 PMID:20436681 GO_REF:0000107 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:29061364) RGD PMID:29061364 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Lcn2 lipocalin 2 IDA RGD PMID:25557118 RGD:126790477 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    localization 5729
      establishment of localization 5079
        establishment of localization in cell 2163
          iron import into cell 12
            endocytic iron import into cell + 1
            heme import into cell + 1
            iron ion import across plasma membrane + 6
            reductive iron assimilation 0
            siderophore-dependent iron import into cell + 0
Path 2
Term Annotations click to browse term
  biological_process 20543
    localization 5729
      establishment of localization 5079
        transport 4766
          monoatomic ion transport 1395
            monoatomic cation transport 1186
              metal ion transport 994
                transition metal ion transport 128
                  iron ion transport 83
                    iron import into cell 12
                      endocytic iron import into cell + 1
                      heme import into cell + 1
                      iron ion import across plasma membrane + 6
                      reductive iron assimilation 0
                      siderophore-dependent iron import into cell + 0
paths to the root