Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:T cell differentiation in thymus
go back to main search page
Accession:GO:0033077 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: thymic T cell differentiation;   thymocyte cell differentiation;   thymocyte differentiation
 related_synonym: T cell development in thymus



show annotations for term's descendants           Sort by:
T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:11067867), (PMID:11435465), (PMID:12163459), (PMID:16670300)
Ensembl
RGD
PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:17371977) RGD PMID:17371977 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO MGI:3589207 (PMID:16025118) RGD PMID:16025118 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO MGI:95663 (PMID:18776904) RGD PMID:18776904 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bcl11b BCL11 transcription factor B acts_upstream_of_or_within ISO MGI:2663971 (PMID:16670294) RGD PMID:16670294 NCBI chr 6:132,598,968...132,692,123
Ensembl chr 6:126,834,531...126,928,224
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2156165 (PMID:8170972), (PMID:9028316)
Ensembl
RGD
PMID:8170972 PMID:9028316 GO_REF:0000107 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO MGI:3711006 (PMID:23334952) RGD PMID:23334952 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex IEP RGD PMID:11896936 RGD:2313407 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cdk6 cyclin-dependent kinase 6 acts_upstream_of_or_within ISO MGI:3833563|MGI:5141514 (PMID:21508411) RGD PMID:21508411 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1858008 (PMID:16025118)
Ensembl
RGD
PMID:16025118 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 acts_upstream_of_or_within ISO MGI:2448686|MGI:3040717 (PMID:15879105) RGD PMID:15879105 NCBI chr10:11,361,168...11,386,599
Ensembl chr10:10,854,732...10,880,161
JBrowse link
G Fadd Fas associated via death domain involved_in ISO
ISS
(PMID:21876153)
GO_REF:0000024
RGD
UniProt
PMID:21876153 GO_REF:0000024 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fzd5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:11265645)
Ensembl
RGD
PMID:11265645 GO_REF:0000107 NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Fzd7 frizzled class receptor 7 acts_upstream_of_or_within ISO (PMID:11265645) RGD PMID:11265645 NCBI chr 9:68,425,538...68,428,357
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
G Fzd8 frizzled class receptor 8 acts_upstream_of_or_within ISO (PMID:11265645) RGD PMID:11265645 NCBI chr17:62,007,849...62,015,485
Ensembl chr17:57,314,450...57,320,650
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2153825|MGI:2683927|MGI:4418042|MGI:88127 (PMID:14670303), (PMID:18776904), (PMID:19934022), (PMID:8945476) RGD PMID:8945476 PMID:14670303 PMID:18776904 PMID:19934022 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:22665763) RGD PMID:22665763 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Gli3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within
ISO (PMID:15855276)
MGI:1856276 (PMID:15855276)
RGD PMID:15855276 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of ISO MGI:1857455|MGI:2429736 (PMID:9252128), (PMID:9916699) RGD PMID:9252128 PMID:9916699 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:66,392,542...66,399,823
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of ISO MGI:1857198 (PMID:9215626) RGD PMID:9215626 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3043930 (PMID:14715629)
Ensembl
RGD
PMID:14715629 GO_REF:0000107 NCBI chr10:102,539,935...102,545,986
Ensembl chr10:102,041,120...102,047,182
JBrowse link
G Mafb MAF bZIP transcription factor B acts_upstream_of_or_within ISO MGI:3663168 (PMID:19164599) RGD PMID:19164599 NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Mpzl2 myelin protein zero-like 2 acts_upstream_of_or_within ISO (PMID:19851463) RGD PMID:19851463 NCBI chr 8:45,348,285...45,359,298
Ensembl chr 8:45,348,285...45,359,298
JBrowse link
G Mr1 major histocompatibility complex, class I-related involved_in IEA
ISO
GO_REF:0000107
(PMID:12634786)
Ensembl
RGD
PMID:12634786 GO_REF:0000107 NCBI chr13:69,850,420...69,868,302
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G Ncaph2 non-SMC condensin II complex, subunit H2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3710093 (PMID:17640884)
Ensembl
RGD
PMID:17640884 GO_REF:0000107 NCBI chr 7:120,422,926...120,439,942
Ensembl chr 7:120,422,956...120,439,938
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 acts_upstream_of_or_within ISO MGI:2677822 (PMID:11030619) RGD PMID:11030619 NCBI chr10:47,498,852...47,641,612
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of ISO (PMID:11931770) RGD PMID:11931770 NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:85,680,861...85,690,447
JBrowse link
G Nkap NFKB activating protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3765313|MGI:4839023 (PMID:20610818)
Ensembl
RGD
PMID:20610818 GO_REF:0000107 NCBI chr  X:121,238,714...121,258,360
Ensembl chr  X:116,372,839...116,394,945
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO MGI:2383951 (PMID:9768755) RGD PMID:9768755 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prr7 proline rich 7 (synaptic) involved_in ISO MGI:4399196 (PMID:27657535) RGD PMID:27657535 NCBI chr17:9,170,405...9,178,814
Ensembl chr17:9,165,269...9,172,536
JBrowse link
G Psmb11 proteasome subunit beta 11 acts_upstream_of_or_within ISO (PMID:31915251) RGD PMID:31915251 NCBI chr15:28,084,736...28,085,655 JBrowse link
G Rabl3 RAB, member of RAS oncogene family-like 3 involved_in ISO (PMID:32220963) RGD PMID:32220963 NCBI chr11:76,658,723...76,687,681
Ensembl chr11:63,152,792...63,182,671
JBrowse link
G Rag1 recombination activating 1 involved_in
acts_upstream_of_or_within
ISO (PMID:1547488)
MGI:2448994 (PMID:9215624)
RGD PMID:1547488 PMID:9215624 NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:87,917,004...87,928,291
JBrowse link
G Rag2 recombination activating 2 involved_in ISO (PMID:1547488) RGD PMID:1547488 NCBI chr 3:108,357,399...108,367,186
Ensembl chr 3:87,902,238...87,911,066
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q61160 (PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Rorc RAR-related orphan receptor C acts_upstream_of_or_within ISO MGI:3026635 (PMID:15247480) RGD PMID:15247480 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Rps6 ribosomal protein S6 acts_upstream_of_or_within ISO MGI:2387471|MGI:98834 (PMID:16357222) RGD PMID:16357222 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of
ISS
ISO
GO_REF:0000024
(PMID:10981962)
(PMID:19273836)
UniProt
RGD
PMID:10981962 PMID:19273836 GO_REF:0000024 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035 (PMID:15294943) RGD PMID:15294943 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:103036 (PMID:15294943)
Ensembl
RGD
PMID:15294943 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Tcf3 transcription factor 3 acts_upstream_of_or_within ISO MGI:2178112 (PMID:18958875) RGD PMID:18958875 NCBI chr 7:9,931,251...9,952,994
Ensembl chr 7:9,280,571...9,302,314
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98159 (PMID:16357222)
Ensembl
RGD
PMID:16357222 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (PMID:11265645) RGD PMID:11265645 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO (PMID:11265645) RGD PMID:11265645 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 acts_upstream_of_or_within ISO MGI:5300200 (PMID:22201126) RGD PMID:22201126 NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:95,096,387...95,118,996
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:P23949 (PMID:20622884)
UniProt
RGD
PMID:20622884 GO_REF:0000024 NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO UniProtKB:P23950 (PMID:20622884) RGD PMID:20622884 NCBI chr 6:16,242,622...16,246,662
Ensembl chr 6:10,490,032...10,494,064
JBrowse link
DN2 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in ISO (PMID:24638065) RGD PMID:24638065 NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:52,474,168...52,498,603
JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO MGI:1857732 (PMID:10911993), (PMID:9823897) RGD PMID:9823897 PMID:10911993 NCBI chr16:86,220,345...86,228,930
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Rag2 recombination activating 2 acts_upstream_of_or_within ISO MGI:1858556 (PMID:9875844) RGD PMID:9875844 NCBI chr 3:108,357,399...108,367,186
Ensembl chr 3:87,902,238...87,911,066
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO MGI:1926771 (PMID:9875844) RGD PMID:9875844 NCBI chr 2:22,686,506...22,932,929
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
DN3 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in ISO (PMID:24638065) RGD PMID:24638065 NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:52,474,168...52,498,603
JBrowse link
DN4 thymocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87860 (PMID:18025176) RGD PMID:18025176 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87859 (PMID:18025176) RGD PMID:18025176 NCBI chr13:71,223,902...71,319,770
Ensembl chr13:68,673,722...68,839,742
JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:3053044|MGI:3663359 (PMID:17210642) RGD PMID:17210642 NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:17579027)
UniProt
RGD
PMID:17579027 GO_REF:0000024 NCBI chr19:50,870,464...50,944,992
Ensembl chr19:33,960,852...34,035,150
JBrowse link
immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of ISO MGI:3053044|MGI:3663359 (PMID:17210642) RGD PMID:17210642 NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of ISO MGI:5510586 (PMID:23487419) RGD PMID:23487419 NCBI chr12:6,578,266...6,582,913
Ensembl chr12:1,780,371...1,784,985
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:16230479)
Ensembl
RGD
PMID:16230479 GO_REF:0000107 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of ISO MGI:1857034 (PMID:16230479) RGD PMID:16230479 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 acts_upstream_of_or_within ISO (PMID:11154225) RGD PMID:11154225 NCBI chr11:44,099,574...44,131,941
Ensembl chr11:30,613,767...30,668,124
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of ISO MGI:2660793 (PMID:11894098) RGD PMID:11894098 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857453 (PMID:18617424)
Ensembl
RGD
PMID:18617424 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12421925)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12421925 GO_REF:0000024 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:15964995) RGD PMID:15964995 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO MGI:5510586 (PMID:23487419) RGD PMID:23487419 NCBI chr12:6,578,266...6,582,913
Ensembl chr12:1,780,371...1,784,985
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16230479)
Ensembl
RGD
PMID:16230479 GO_REF:0000107 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (PMID:19109233) RGD PMID:19109233 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Tmem131l transmembrane 131 like involved_in ISO (PMID:23690469) RGD PMID:23690469 NCBI chr 2:169,257,659...169,391,773
Ensembl chr 2:169,258,289...169,391,711
JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
ISS
IEA
(PMID:22080863)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:22080863 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627
JBrowse link
negative regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:12421925) RGD PMID:12421925 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Foxj1 forkhead box J1 involved_in IEA
ISO
GO_REF:0000107
(PMID:16339515)
Ensembl
RGD
PMID:16339515 GO_REF:0000107 NCBI chr10:102,065,163...102,069,945
Ensembl chr10:101,566,304...101,570,237
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (PMID:19109233) RGD PMID:19109233 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of_or_within ISO (PMID:11931770) RGD PMID:11931770 NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:85,680,861...85,690,447
JBrowse link
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:108,357,399...108,367,186
Ensembl chr 3:87,902,238...87,911,066
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:10981962)
Ensembl
RGD
PMID:10981962 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Zc3h8 zinc finger CCCH type containing 8 involved_in ISO (PMID:12153508) RGD PMID:12153508 NCBI chr 3:136,629,998...136,646,998
Ensembl chr 3:116,176,798...116,193,787
JBrowse link
negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1277186 (PMID:23382543)
GO_REF:0000033
RGD
GO_Central
PMID:23382543 GO_REF:0000033 NCBI chr20:10,635,775...10,650,709
Ensembl chr20:10,636,123...10,651,060
JBrowse link
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1338803|MGI:3612279 (PMID:23382543)
Ensembl
RGD
PMID:23382543 GO_REF:0000107 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (PMID:17785582) RGD PMID:17785582 NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:10429671) RGD PMID:10429671 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:7630421) RGD PMID:7630421 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205 (PMID:7679955) RGD PMID:7679955 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO MGI:2152031 (PMID:12871644) RGD PMID:12871644 NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808
JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO MGI:1856334 (PMID:10429671) RGD PMID:10429671 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (PMID:19667090) RGD PMID:19667090 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Mink1 misshapen-like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) RGD PMID:15608642 NCBI chr10:55,776,879...55,829,406
Ensembl chr10:55,278,391...55,330,782
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:17227833)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17227833 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (PMID:10429671) RGD PMID:10429671 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO MGI:2677447 (PMID:7630421) RGD PMID:7630421 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700
JBrowse link
positive regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:3053044|MGI:3663359 (PMID:17210642) RGD PMID:17210642 NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger involved_in ISO (PMID:15964995) RGD PMID:15964995 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:1857034 (PMID:16230479) RGD PMID:16230479 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Il1a interleukin 1 alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:8590311 GO_REF:0000033, RGD:7401228 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (PMID:11894098) RGD PMID:11894098 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:14764698), (PMID:19273836)
UniProt
Ensembl
RGD
PMID:14764698 PMID:19273836 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
positive regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:11067867), (PMID:11435465), (PMID:12163459), (PMID:16670300)
Ensembl
RGD
PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (PMID:20856819) RGD PMID:20856819 NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Egr3 early growth response 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:21737317)
Ensembl
RGD
PMID:21737317 GO_REF:0000107 NCBI chr15:51,560,482...51,565,778
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (PMID:19109233) RGD PMID:19109233 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO MGI:1857455|MGI:2429736 (PMID:9252128), (PMID:9916699) RGD PMID:9252128 PMID:9916699 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:66,392,542...66,399,823
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (PMID:9215626) RGD PMID:9215626 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:11017103)
Ensembl
RGD
PMID:11017103 GO_REF:0000107 NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19109233)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19109233 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Vnn1 vanin 1 involved_in ISO (PMID:8934567) RGD PMID:8934567 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within ISO MGI:2180711 (PMID:9133426) RGD PMID:9133426 NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cd3d CD3 delta subunit of T-cell receptor complex involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:9135151)
UniProt
GO_Central
RGD
PMID:9135151 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:54,184,573...54,190,112
Ensembl chr 8:45,288,749...45,301,809
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:45,281,204...45,287,147
JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205|MGI:1927530 (PMID:7679955), (PMID:8598040), (PMID:9432982) RGD PMID:7679955 PMID:8598040 PMID:9432982 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO MGI:2152031 (PMID:12871644) RGD PMID:12871644 NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO MGI:3039799 (PMID:15064401) RGD PMID:15064401 NCBI chr13:94,601,072...94,696,180
Ensembl chr13:92,069,216...92,162,004
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:17579027)
UniProt
RGD
PMID:17579027 GO_REF:0000024 NCBI chr19:50,870,464...50,944,992
Ensembl chr19:33,960,852...34,035,150
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G RT1-DMa RT1 class II, locus DMa acts_upstream_of_or_within ISO MGI:1861933|MGI:2384509|MGI:2652160 (PMID:8598040), (PMID:8598041), (PMID:8638109), (PMID:9432982) RGD PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,707,028...4,710,432
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:17227833)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17227833 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2449947|MGI:3046779 (PMID:21098124) RGD PMID:21098124 NCBI chr 9:21,924,050...21,933,338
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO MGI:2386448|MGI:2387402|MGI:3054844 (PMID:21487392) RGD PMID:21487392 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO (PMID:7630421)
MGI:2677447 (PMID:7630421)
RGD PMID:7630421 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700
JBrowse link
regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule involved_in ISO (PMID:11550008) RGD PMID:11550008 NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 acts_upstream_of_or_within ISO (PMID:8405064) RGD PMID:8405064 NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnfsf9 TNF superfamily member 9 acts_upstream_of_or_within ISO (PMID:8405064) RGD PMID:8405064 NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:1,944,017...1,946,345
JBrowse link
regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxn1 forkhead box N1 involved_in ISO (PMID:24184560) RGD PMID:24184560 NCBI chr10:63,749,461...63,778,468
Ensembl chr10:63,251,400...63,273,710
JBrowse link
G Tox thymocyte selection-associated high mobility group box involved_in ISO (PMID:18195075) RGD PMID:18195075 NCBI chr 5:24,672,487...24,968,754
Ensembl chr 5:19,874,467...20,171,272
JBrowse link
regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP RGD PMID:3876160 RGD:152995412 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor involved_in ISO (PMID:21048919) RGD PMID:21048919 NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195
JBrowse link
G Ankle1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (PMID:27010503) RGD PMID:27010503 NCBI chr16:18,109,865...18,116,999
Ensembl chr16:18,076,492...18,083,729
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking involved_in ISO (PMID:9218588) RGD PMID:9218588 NCBI chr 1:88,417,447...88,449,047
Ensembl chr 1:79,289,477...79,321,092
JBrowse link
G Foxn1 forkhead box N1 acts_upstream_of_or_within ISO MGI:5297717 (PMID:22072979) RGD PMID:22072979 NCBI chr10:63,749,461...63,778,468
Ensembl chr10:63,251,400...63,273,710
JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:25065622) RGD PMID:25065622 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:98355 (PMID:24043312) RGD PMID:24043312 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 acts_upstream_of_or_within ISO MGI:98354 (PMID:24043312) RGD PMID:24043312 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:88,042,966...88,156,692
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857515|MGI:1857799 (PMID:9126927), (PMID:9389660)
Ensembl
RGD
PMID:9126927 PMID:9389660 GO_REF:0000107 NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214
JBrowse link
thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family, member 11 acts_upstream_of_or_within ISO MGI:3039682 (PMID:12867038) RGD PMID:12867038 NCBI chr12:18,735,088...18,872,045
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2683927 (PMID:14670303) RGD PMID:14670303 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO MGI:2680720 (PMID:14517551) RGD PMID:14517551 NCBI chr13:94,601,072...94,696,180
Ensembl chr13:92,069,216...92,162,004
JBrowse link
G Jag2 jagged canonical Notch ligand 2 involved_in IEA
ISS
ISO
GO_REF:0000107
PMID:10383933
(PMID:10383933)
Ensembl
RGD
PMID:10383933 PMID:10383933 GO_REF:0000107, RGD:8553281 NCBI chr 6:137,804,133...137,826,738
Ensembl chr 6:131,983,056...132,005,818
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO MGI:2677447|MGI:3526403 (PMID:9208839) RGD PMID:9208839 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    immune system process 3112
      leukocyte activation 1069
        lymphocyte activation 866
          lymphocyte differentiation 446
            T cell differentiation 332
              T cell differentiation in thymus 104
                DN2 thymocyte differentiation 4
                DN3 thymocyte differentiation 1
                DN4 thymocyte differentiation 4
                immature T cell proliferation in thymus + 18
                negative regulation of T cell differentiation in thymus + 12
                positive regulation of T cell differentiation in thymus + 9
                regulation of T cell differentiation in thymus + 28
                thymic T cell selection + 28
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      cellular developmental process 4812
        cell differentiation 4811
          cell development 3339
            hemopoiesis 1079
              leukocyte differentiation 685
                mononuclear cell differentiation 549
                  lymphocyte differentiation 446
                    T cell differentiation 332
                      T cell differentiation in thymus 104
                        DN2 thymocyte differentiation 4
                        DN3 thymocyte differentiation 1
                        DN4 thymocyte differentiation 4
                        immature T cell proliferation in thymus + 18
                        negative regulation of T cell differentiation in thymus + 12
                        positive regulation of T cell differentiation in thymus + 9
                        regulation of T cell differentiation in thymus + 28
                        thymic T cell selection + 28
paths to the root