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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to insulin stimulus
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Accession:GO:0032869 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.


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cellular response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 IEP RGD PMID:16198472 RGD:2312808 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 IEP RGD PMID:16428347 RGD:1599808 NCBI chr10:38,940,668...38,999,515
Ensembl chr10:38,440,080...38,498,757 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing acts_upstream_of_or_within
involved_in		 IDA
ISO
ISS		 MGI:88157 (PMID:17693256)
GO_REF:0000024		 RGD
UniProt		 PMID:17693256 PMID:21401303 GO_REF:0000024, RGD:5686346 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein IEP RGD PMID:7513166 RGD:1626076 NCBI chr11:91,625,975...91,632,583
Ensembl chr11:78,117,918...78,145,999 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IMP
IEA
IDA
ISO
ISS		 PMID:10454575
GO_REF:0000107
(PMID:19139280)
(PMID:17715136)
GO_REF:0000024
(PMID:12172553), (PMID:16814735), (PMID:17386266), (PMID:24529379)		 Ensembl
RGD
UniProt		 PMID:12172553 PMID:16814735 PMID:17386266 PMID:17715136 PMID:19139280 More... GO_REF:0000024 GO_REF:0000107, RGD:8553650, RGD:407572520, RGD:407420264, RGD:8553574 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA
IMP		 (PMID:16814735)
GO_REF:0000107
PMID:17715136		 RGD
Ensembl		 PMID:16814735 PMID:17715136 GO_REF:0000107, RGD:8553574 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 acts_upstream_of_or_within IMP PMID:17715136 MGI PMID:17715136 RGD:8553574 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 IEP RGD PMID:11716532 RGD:4144187 NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B IEP also dexamethasone, glucagon RGD PMID:9473304 RGD:1599069 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 IEP RGD PMID:9667237 RGD:1626288 NCBI chr 4:157,472,879...157,500,496
Ensembl chr 4:155,800,887...155,827,390 		JBrowse link
G Aprt adenine phosphoribosyl transferase IEP RGD PMID:2185659 RGD:2316798 NCBI chr19:67,534,737...67,537,027
Ensembl chr19:50,626,202...50,628,431 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding IEP RGD PMID:30950934 RGD:153350153 NCBI chr12:22,044,685...22,051,248
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:17693256), (PMID:20655470), (PMID:20655471)		 UniProt
RGD		 PMID:17693256 PMID:20655470 PMID:20655471 GO_REF:0000024 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Capn10 calpain 10 involved_in ISO
IEA		 (PMID:17572128)
(PMID:12974673)
GO_REF:0000107		 RGD
Ensembl		 PMID:12974673 PMID:17572128 GO_REF:0000107 NCBI chr 9:100,943,665...100,957,910
Ensembl chr 9:93,498,478...93,510,494 		JBrowse link
G Car3 carbonic anhydrase 3 IEP RGD PMID:15500001 RGD:408427359 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP RGD PMID:17180354 RGD:8549642 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnd2 cyclin D2 IEP RGD PMID:16210359 RGD:1582339 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cd36 CD36 molecule IEP RGD PMID:19273501 RGD:2307221 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdk2 cyclin dependent kinase 2 IDA RGD PMID:15994754 RGD:2293572 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IDA PMID:7626603 UniProt PMID:7626603 RGD:11059572 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IEP RGD PMID:18292530 RGD:11341712 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 IEP RGD PMID:22992739 RGD:28912745 NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO
ISS		 (PMID:18752464)
GO_REF:0000024		 RGD
UniProt		 PMID:18752464 GO_REF:0000024 NCBI chr 1:144,709,278...144,817,388
Ensembl chr 1:135,300,461...135,409,760 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 involved_in ISO
ISS		 (PMID:18752464)
GO_REF:0000024		 RGD
UniProt		 PMID:18752464 GO_REF:0000024 NCBI chr14:71,999,958...72,056,012
Ensembl chr14:67,787,507...67,840,743 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 IMP RGD PMID:16260607 RGD:11557987 NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Dennd4c DENN domain containing 4C involved_in ISO (PMID:21454697) RGD PMID:21454697 NCBI chr 5:101,272,298...101,369,529
Ensembl chr 5:101,272,005...101,368,118 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein IEP RGD PMID:16338927 RGD:2304073 NCBI chr16:61,954,177...62,374,819
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dpep1 dipeptidase 1 involved_in ISO (PMID:17615681) RGD PMID:17615681 NCBI chr19:68,118,270...68,143,781
Ensembl chr19:51,219,660...51,235,257 		JBrowse link
G Drd1 dopamine receptor D1 IEP RGD PMID:12707290 RGD:2302121 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase IEP RGD PMID:9841860 RGD:10401230 NCBI chr 1:184,824,420...184,888,048
Ensembl chr 1:175,393,154...175,455,164 		JBrowse link
G Egr1 early growth response 1 IEP RGD PMID:12970165 RGD:1601014 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:17849011), (PMID:7830796) RGD PMID:7830796 PMID:17849011 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G ENSRNOG00000065303 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr15:64,319,958...64,321,500 JBrowse link
G ENSRNOG00000068788 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:178,160,230...178,162,162 JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 involved_in ISO
IEA		 (PMID:28178239)
GO_REF:0000107		 RGD
Ensembl		 PMID:28178239 GO_REF:0000107 NCBI chr13:99,431,955...99,503,510
Ensembl chr13:96,901,575...96,971,966 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 IEP RGD PMID:9389501 RGD:2289971 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IEP RGD PMID:15358516 RGD:9685544 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 IEP RGD PMID:2847161 PMID:9530152 RGD:1298915, RGD:151665787 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Foxo1 forkhead box O1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17681146)		 UniProt
Ensembl
RGD		 PMID:17681146 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 IEP RGD PMID:19579180 RGD:14695551 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gck glucokinase involved_in IDA PMID:17470517 BHF-UCL PMID:17470517 RGD:8554539 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit IEP RGD PMID:15169830 RGD:10402381 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 IEP RGD PMID:10604279 RGD:1625427 NCBI chr 4:121,054,023...121,103,799
Ensembl chr 4:119,496,714...119,546,471 		JBrowse link
G Ggcx gamma-glutamyl carboxylase acts_upstream_of_or_within ISO (PMID:17693256), (PMID:20655470), (PMID:20655471) RGD PMID:17693256 PMID:20655470 PMID:20655471 NCBI chr 4:106,027,918...106,043,653
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Gh1 growth hormone 1 acts_upstream_of_or_within ISO
IEA		 (PMID:16513828)
GO_REF:0000107		 RGD
Ensembl		 PMID:16513828 GO_REF:0000107 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Ghr growth hormone receptor IEP RGD PMID:18040895 RGD:2307371 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor acts_upstream_of_or_within ISO
IEA		 (PMID:16513828)
GO_REF:0000107		 RGD
Ensembl		 PMID:16513828 GO_REF:0000107 NCBI chr 4:85,830,345...85,863,127
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Ghsr growth hormone secretagogue receptor acts_upstream_of_or_within ISO
IEA		 (PMID:16513828)
GO_REF:0000107		 RGD
Ensembl		 PMID:16513828 GO_REF:0000107 NCBI chr 2:112,196,158...112,201,666
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISO
IEA		 (PMID:8396422)
GO_REF:0000107		 RGD
Ensembl		 PMID:8396422 GO_REF:0000107 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial IDA RGD PMID:18167308 RGD:2313661 NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO
IEA
ISS		 (PMID:15907827)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15907827 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Gpt glutamic--pyruvic transaminase IEP RGD PMID:25865565 RGD:11342811 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 IEP RGD PMID:25865565 RGD:11342811 NCBI chr19:37,700,023...37,734,551
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Grb14 growth factor receptor bound protein 14 involved_in IMP PMID:14623073 CAFA PMID:14623073 RGD:12793049 NCBI chr 3:69,976,331...70,091,921
Ensembl chr 3:49,568,210...49,683,889 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:17569761) RGD PMID:17569761 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 IEP RGD PMID:1908848 RGD:2317845 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G H2az1 H2A.Z variant histone 1 IDA RGD PMID:24471919 RGD:9588479 NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485 		JBrowse link
G Hdac9 histone deacetylase 9 involved_in ISO (PMID:19303849) RGD PMID:19303849 NCBI chr 6:56,489,472...57,351,654
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP RGD PMID:16506055 RGD:1626318 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 IEP RGD PMID:12027802 RGD:1599891 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K IDA
IEP		 RGD PMID:15485813 PMID:21291866 PMID:16837467 RGD:10002778, RGD:10058978, RGD:10002795 NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IEP RGD PMID:2185659 RGD:2316798 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:2177628 RGD:4889586 NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Igf1 insulin-like growth factor 1 IEP RGD PMID:20013160 RGD:10046039 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor acts_upstream_of_or_within IEP
ISO		 MGI:2386329 (PMID:21677284) RGD PMID:21677284 PMID:20013160 RGD:10046039 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Inhbb inhibin subunit beta B involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19491194)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19491194 GO_REF:0000024 GO_REF:0000107 NCBI chr13:33,083,671...33,089,373
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO
IEA		 (PMID:12556481)
GO_REF:0000107		 RGD
Ensembl		 PMID:12556481 GO_REF:0000107 NCBI chr10:60,974,183...60,995,047
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Insig1 insulin induced gene 1 involved_in IEP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:19299314 GO_REF:0000033, RGD:2308854 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Insr insulin receptor involved_in ISO (PMID:8440175) RGD PMID:8440175 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Irs1 insulin receptor substrate 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:16814735)
(PMID:11375348)		 RGD PMID:11375348 PMID:16814735 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irs2 insulin receptor substrate 2 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 GO_REF:0000107
(PMID:11375348)
(PMID:16814735)		 Ensembl
RGD		 PMID:11375348 PMID:16814735 PMID:22912850 GO_REF:0000107, RGD:7257698 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO
IEA		 (PMID:19303849)
GO_REF:0000107		 RGD
Ensembl		 PMID:19303849 GO_REF:0000107 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO
IEA		 (PMID:29519872)
GO_REF:0000107		 RGD
Ensembl		 PMID:29519872 GO_REF:0000107 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G LOC120102490 insulin-induced gene 1 protein-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:67,330,399...67,331,371
Ensembl chr 4:67,330,588...67,331,346 		JBrowse link
G Lpin1 lipin 1 acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA		 MGI:1856603 (PMID:10438476)
GO_REF:0000033		 RGD
GO_Central		 PMID:10438476 PMID:11792863 GO_REF:0000033, RGD:1641823 NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Lpin2 lipin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:118,529,988...118,604,796
Ensembl chr 9:111,083,745...111,158,193 		JBrowse link
G Lpin3 lipin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:169,953,479...169,978,034
Ensembl chr 3:149,534,051...149,558,327 		JBrowse link
G Mapkap1 MAPK associated protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23142081)		 UniProt
RGD		 PMID:23142081 GO_REF:0000024 NCBI chr 3:38,113,268...38,315,913
Ensembl chr 3:17,715,834...17,918,384 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO
IEA
ISS		 (PMID:18372248)
GO_REF:0000107
(PMID:23142081)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18372248 PMID:23142081 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Muc4 mucin 4, cell surface associated IEP RGD PMID:10980611 RGD:2303745 NCBI chr11:81,513,321...81,575,200 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP RGD PMID:2200903 RGD:10059628 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myo5a myosin VA involved_in ISS
ISO		 GO_REF:0000024
(PMID:22908308)		 UniProt
RGD		 PMID:22908308 GO_REF:0000024 NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Nos3 nitric oxide synthase 3 IEP RGD PMID:29055722 RGD:13450916 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase IEP RGD PMID:15561949 RGD:9590198 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Otop1 otopetrin 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24379350)		 UniProt
Ensembl
RGD		 PMID:24379350 GO_REF:0000024 GO_REF:0000107 NCBI chr14:76,717,330...76,744,785
Ensembl chr14:72,503,592...72,532,497 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IDA RGD PMID:8702668 RGD:2299859 NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
IEA		 (PMID:19303849)
GO_REF:0000107		 RGD
Ensembl		 PMID:19303849 GO_REF:0000107 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pax6 paired box 6 IEP RGD PMID:18189319 RGD:8552378 NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in IEP
IBA
ISS
ISO		 GO_REF:0000033
GO_REF:0000024
(PMID:32322062)		 GO_Central
UniProt
RGD		 PMID:32322062 PMID:21519922 PMID:9530152 GO_REF:0000024 GO_REF:0000033, RGD:10428394, RGD:151665787 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:32,997,853...33,006,691
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in IDA
IEA
ISO		 PMID:16407292
GO_REF:0000107
(PMID:16407292)		 Ensembl
RGD		 PMID:16407292 PMID:16407292 GO_REF:0000107, RGD:8553473 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Pde3b phosphodiesterase 3B involved_in ISS
ISO		 GO_REF:0000024
(PMID:10454575)		 BHF-UCL
RGD		 PMID:10454575 GO_REF:0000024 NCBI chr 1:178,041,207...178,204,503
Ensembl chr 1:168,607,022...168,769,334 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA		 (PMID:10567711)
GO_REF:0000107		 RGD
Ensembl		 PMID:10567711 GO_REF:0000107 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO
IEA		 (PMID:24529379)
GO_REF:0000107		 RGD
Ensembl		 PMID:24529379 GO_REF:0000107 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEP
ISO
ISS		 increased IRS1 binding
(PMID:20348926)
(PMID:27708159)
GO_REF:0000024		 RGD
UniProt		 PMID:20348926 PMID:27708159 PMID:18922131 GO_REF:0000024, RGD:4108484 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20348926)		 UniProt
Ensembl
RGD		 PMID:20348926 GO_REF:0000024 GO_REF:0000107 NCBI chr16:18,699,389...18,708,045
Ensembl chr16:18,665,457...18,674,065 		JBrowse link
G Pklr pyruvate kinase L/R involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:9395079 GO_REF:0000033, RGD:1625596 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Pkm pyruvate kinase M1/2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Pkm_v1 pyruvate kinase M1/2, variant 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Pkm_v2 pyruvate kinase M1/2, variant 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Pkml1 pyruvate kinase M1/2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:70,838,572...70,840,735
Ensembl chr16:70,838,568...70,840,795 		JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISS
ISO		 PMID:1918029
(PMID:1918029)		 RGD PMID:1918029 PMID:1918029 RGD:8553780 NCBI chr12:46,802,932...46,814,511
Ensembl chr12:41,142,200...41,153,226 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 IEP RGD PMID:19619606 RGD:14985223 NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:115,293,538...115,314,077 		JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISO
IEA		 (PMID:26670484)
GO_REF:0000107		 RGD
Ensembl		 PMID:26670484 GO_REF:0000107 NCBI chr19:46,390,958...46,394,599
Ensembl chr19:29,486,686...29,490,327 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:10622252)
(PMID:26629404)
GO_REF:0000024		 RGD
UniProt		 PMID:10622252 PMID:26629404 GO_REF:0000024 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase IEP RGD PMID:2185659 RGD:2316798 NCBI chr14:31,570,010...31,604,410
Ensembl chr14:31,216,165...31,250,144 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IEP RGD PMID:11884620 RGD:729591 NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Prkcd protein kinase C, delta IEP RGD PMID:17046201 RGD:1642545 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkci protein kinase C, iota involved_in IMP
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:9819385)		 Ensembl
GO_Central
RGD		 PMID:9819385 PMID:12975478 GO_REF:0000033 GO_REF:0000107, RGD:2314946 NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:112,321,929...112,382,352 		JBrowse link
G Prkcz protein kinase C, zeta involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16525020 GO_REF:0000033, RGD:1642671 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:19303849) RGD PMID:19303849 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Pten phosphatase and tensin homolog IDA RGD PMID:12700235 RGD:12801493 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 IEP RGD PMID:18456732 RGD:401976379 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Rab10 RAB10, member RAS oncogene family involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:17403373), (PMID:22908308)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17403373 PMID:22908308 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:31,974,858...32,039,554
Ensembl chr 6:26,266,859...26,320,193 		JBrowse link
G Rab13 RAB13, member RAS oncogene family involved_in IMP PMID:21041651 UniProt PMID:21041651 RGD:8554419 NCBI chr 2:177,972,535...177,977,679
Ensembl chr 2:175,675,005...175,680,036 		JBrowse link
G Rab31 RAB31, member RAS oncogene family involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:17189207)		 Ensembl
UniProt
RGD		 PMID:17189207 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:112,693,596...112,828,104
Ensembl chr 9:105,246,709...105,381,253 		JBrowse link
G Rab8a RAB8A, member RAS oncogene family involved_in IMP PMID:21041651 UniProt PMID:21041651 RGD:8554419 NCBI chr16:17,688,049...17,709,412
Ensembl chr16:17,654,034...17,675,678 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 IEP RGD PMID:23328001 RGD:15036821 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEP RGD PMID:19002579 RGD:10003129 NCBI chr 8:99,324,986...99,454,099
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18638549)		 Ensembl
RGD		 PMID:18638549 GO_REF:0000107 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rhoq ras homolog family member Q involved_in ISO (PMID:11309621)
(PMID:11821390)		 RGD PMID:11309621 PMID:11821390 NCBI chr 6:13,368,499...13,403,929
Ensembl chr 1:106,622,141...106,623,699 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3619426 (PMID:24349514)
GO_REF:0000033		 RGD
GO_Central		 PMID:24349514 GO_REF:0000033 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rxra retinoid X receptor alpha IEP RGD PMID:9555940 RGD:1643120 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:10590062 RGD:8547811 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 acts_upstream_of_or_within IMP PMID:17715136 MGI PMID:17715136 RGD:8553574 NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Shc1 SHC adaptor protein 1 IEP RGD PMID:11884620 RGD:729591 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Slc22a12 solute carrier family 22 member 12 IEP RGD PMID:28679589 RGD:13439745 NCBI chr 1:213,274,266...213,282,793
Ensembl chr 1:203,845,048...203,853,555 		JBrowse link
G Slc25a33 solute carrier family 25 member 33 involved_in ISO (PMID:17596519) RGD PMID:17596519 NCBI chr 5:165,478,070...165,518,186
Ensembl chr 5:160,195,042...160,219,961 		JBrowse link
G Slc29a2 solute carrier family 29 member 2 IEP RGD PMID:17537394 RGD:2316934 NCBI chr 1:211,756,588...211,764,561
Ensembl chr 1:202,327,354...202,335,171 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 involved_in
acts_upstream_of_or_within		 IEP
IEA
ISO
IBA		 GO_REF:0000107
(PMID:26240143)
(PMID:18227281)
GO_REF:0000033
GO_REF:0000002
(PMID:12556481)		 Ensembl
RGD
GO_Central
InterPro		 PMID:12556481 PMID:18227281 PMID:26240143 PMID:20868366 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:7349316 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO
IEA		 (PMID:27703010)
GO_REF:0000107		 RGD
Ensembl		 PMID:27703010 GO_REF:0000107 NCBI chr15:51,786,517...51,833,260
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 IDA RGD PMID:20868366 RGD:7349316 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 involved_in ISO (PMID:11001060) RGD PMID:11001060 NCBI chr 1:249,057,324...249,279,703
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sp1 Sp1 transcription factor involved_in IDA PMID:26908121 ParkinsonsUK-UCL PMID:26908121 RGD:11059577 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:19952103 RGD:2325147 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:20810561 RGD:4891501 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 IEP RGD PMID:19158095 PMID:24458133 PMID:10207099 RGD:2308803, RGD:401842379, RGD:2308847 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf1_v2 sterol regulatory element binding factor 1, variant 2 IEP RGD PMID:19158095 PMID:10207099 RGD:2308803, RGD:2308847
G Srsf5 serine and arginine rich splicing factor 5 IEP RGD PMID:7686911 RGD:729792 NCBI chr 6:106,333,998...106,341,467
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:17023532 RGD:1600072 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA RGD PMID:15749807 RGD:1600096 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Syap1 synapse associated protein 1 involved_in ISO
IEA		 (PMID:23300339)
GO_REF:0000107		 RGD
Ensembl		 PMID:23300339 GO_REF:0000107 NCBI chr  X:35,423,947...35,458,472
Ensembl chr  X:31,792,193...31,826,667 		JBrowse link
G Tat tyrosine aminotransferase IEP RGD PMID:2575213 RGD:597621663 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 GO_REF:0000107
MGI:3619426 (PMID:24349514)
(PMID:22908308)		 Ensembl
RGD		 PMID:22908308 PMID:24349514 PMID:21454690 GO_REF:0000107, RGD:7247577 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Trarg1 trafficking regulator of GLUT4 (SLC2A4) 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:26240143)
(PMID:26629404)		 UniProt
RGD		 PMID:26240143 PMID:26629404 GO_REF:0000024 NCBI chr10:62,019,281...62,039,666
Ensembl chr10:61,521,107...61,541,494 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO
IEA		 (PMID:12791994)
GO_REF:0000107		 RGD
Ensembl		 PMID:12791994 GO_REF:0000107 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Tsc2 TSC complex subunit 2 acts_upstream_of_or_within ISO (PMID:18511518) RGD PMID:18511518 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B IEP RGD PMID:8048511 RGD:1299378 NCBI chr10:36,749,365...36,764,335
Ensembl chr10:36,248,438...36,264,665 		JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 involved_in ISO (PMID:19837878) RGD PMID:19837878 NCBI chr15:84,888,847...84,942,095
Ensembl chr15:78,485,315...78,527,355
Ensembl chr 3:78,485,315...78,527,355 		JBrowse link
G Ucp2 uncoupling protein 2 IEP RGD PMID:18079609 RGD:2313533 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Usf1 upstream transcription factor 1 involved_in ISO
IEA		 (PMID:19303849)
GO_REF:0000107		 RGD
Ensembl		 PMID:19303849 GO_REF:0000107 NCBI chr13:86,377,679...86,385,523
Ensembl chr13:83,822,035...83,854,885 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 acts_upstream_of_or_within ISO (PMID:18227281) RGD PMID:18227281 NCBI chr10:54,292,423...54,296,657
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vldlr very low density lipoprotein receptor IEP RGD PMID:15878964 RGD:1625575 NCBI chr 1:234,239,769...234,272,150
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 acts_upstream_of_or_within ISO
IEA		 MGI:3774270 (PMID:17767906)
GO_REF:0000107		 RGD
Ensembl		 PMID:17767906 GO_REF:0000107 NCBI chr 5:150,775,358...150,843,558
Ensembl chr 5:145,491,466...145,540,408 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:20348926) RGD PMID:20348926 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma IDA RGD PMID:21454690 RGD:7247577 NCBI chr12:26,381,106...26,409,466
Ensembl chr12:20,744,535...20,772,827 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISO
ISS		 (PMID:15538381)
GO_REF:0000024		 RGD
UniProt		 PMID:15538381 GO_REF:0000024 NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
glucose import in response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sgcb sarcoglycan, beta acts_upstream_of_or_within ISO (PMID:19494113) RGD PMID:19494113 NCBI chr14:34,917,663...34,932,661
Ensembl chr14:34,563,608...34,578,583 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23024797)		 Ensembl
RGD		 PMID:23024797 GO_REF:0000107 NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Slc27a4 solute carrier family 27 member 4 involved_in ISO
IEA		 (PMID:23024797)
GO_REF:0000107		 RGD
Ensembl		 PMID:23024797 GO_REF:0000107 NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:13,075,022...13,087,943 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO
ISS		 PMID:2645527
GO_REF:0000107
(PMID:26240143)
(PMID:26629404)
PMID:2211693
PMID:2649253
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26240143 PMID:26629404 PMID:2645527 PMID:2211693 PMID:2649253 GO_REF:0000024 GO_REF:0000107, RGD:14402447, RGD:2303167, RGD:729967 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Trarg1 trafficking regulator of GLUT4 (SLC2A4) 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:26240143)
(PMID:26629404)		 UniProt
RGD		 PMID:26240143 PMID:26629404 GO_REF:0000024 NCBI chr10:62,019,281...62,039,666
Ensembl chr10:61,521,107...61,541,494 		JBrowse link
G Zdhhc7 zinc finger DHHC-type palmitoyltransferase 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28057756)		 UniProt
RGD		 PMID:28057756 GO_REF:0000024 NCBI chr19:65,048,140...65,065,286
Ensembl chr19:48,139,527...48,156,673 		JBrowse link
insulin receptor recycling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsd cathepsin D involved_in ISO
IEA		 (PMID:27703010)
GO_REF:0000107		 RGD
Ensembl		 PMID:27703010 GO_REF:0000107 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ide insulin degrading enzyme involved_in ISO (PMID:27703010) RGD PMID:27703010 NCBI chr 1:244,415,495...244,516,925
Ensembl chr 1:234,995,351...235,102,440 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IEA		 MGI:2384135 (PMID:17068137)
GO_REF:0000107		 RGD
Ensembl		 PMID:17068137 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15632081)		 Ensembl
RGD		 PMID:15632081 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO
IEA		 (PMID:27322061)
GO_REF:0000107		 RGD
Ensembl		 PMID:27322061 GO_REF:0000107 NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
insulin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS
ISO
IEA
IDA
IMP		 GO_REF:0000024
(PMID:11282895), (PMID:20889126), (PMID:9415393)
(PMID:24508636)
GO_REF:0000107
PMID:8524413
PMID:9632753
(PMID:8978681)		 UniProt
RGD
Ensembl		 PMID:8978681 PMID:9415393 PMID:11282895 PMID:20889126 PMID:24508636 More... GO_REF:0000024 GO_REF:0000107, RGD:8554844, RGD:8554450 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16814735)
GO_REF:0000107
(PMID:21148297)		 RGD
Ensembl		 PMID:16814735 PMID:21148297 GO_REF:0000107 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Ankrd26 ankyrin repeat domain containing 26 acts_upstream_of ISO MGI:3774418 (PMID:21842266) RGD PMID:21842266 NCBI chr 4:153,342,901...153,412,321
Ensembl chr 4:151,672,037...151,739,968 		JBrowse link
G Apc APC regulator of WNT signaling pathway involved_in ISO (PMID:28057765) RGD PMID:28057765 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO
IBA		 (PMID:26073777)
GO_REF:0000033		 RGD
GO_Central		 PMID:26073777 GO_REF:0000033 NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in IDA PMID:9627109 UniProt PMID:9627109 RGD:8553632 NCBI chr19:56,588,500...56,623,190
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member involved_in ISO
IEA
IBA
ISS		 (PMID:24216110)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:24216110 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:213,209,907...213,323,305
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Blvra biliverdin reductase A acts_upstream_of_or_within ISO (PMID:27738106) RGD PMID:27738106 NCBI chr 3:134,793,397...134,819,367
Ensembl chr 3:114,340,838...114,366,033 		JBrowse link
G C2cd5 C2 calcium-dependent domain containing 5 involved_in ISO (PMID:21907143) RGD PMID:21907143 NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558 		JBrowse link
G Cav2 caveolin 2 involved_in IDA
IBA
ISO
IEA		 PMID:20455999
GO_REF:0000033
(PMID:20455999)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:20455999 PMID:20455999 GO_REF:0000033 GO_REF:0000107, RGD:10047313 NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO
IEA		 MGI:2153356 (PMID:19114551)
GO_REF:0000107		 RGD
Ensembl		 PMID:19114551 GO_REF:0000107 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 acts_upstream_of_or_within ISO
IEA		 MGI:1858015 (PMID:29634311)
GO_REF:0000107		 RGD
Ensembl		 PMID:29634311 GO_REF:0000107 NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Dnai1 dynein, axonemal, intermediate chain 1 involved_in ISO
IEA		 (PMID:28057765)
GO_REF:0000107		 RGD
Ensembl		 PMID:28057765 GO_REF:0000107 NCBI chr 5:61,526,079...61,596,806
Ensembl chr 5:56,730,179...56,800,925 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 acts_upstream_of_or_within ISO (PMID:7629182) RGD PMID:7629182 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 acts_upstream_of_or_within ISO
IEA		 (PMID:8939971)
GO_REF:0000107		 RGD
Ensembl		 PMID:8939971 GO_REF:0000107 NCBI chr20:29,922,260...29,942,922
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Fer FER tyrosine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:11006284)		 UniProt
Ensembl
RGD		 PMID:11006284 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Foxc2 forkhead box C2 involved_in ISO (PMID:16456100) RGD PMID:16456100 NCBI chr19:66,094,718...66,097,420
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Foxo1 forkhead box O1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:18293098)
GO_REF:0000107
MGI:2447732|MGI:96160 (PMID:12488434), (PMID:29867121)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:12488434 PMID:18293098 PMID:29867121 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxo4 forkhead box O4 involved_in ISO
IEA		 (PMID:10217147)
GO_REF:0000107		 RGD
Ensembl		 PMID:10217147 GO_REF:0000107 NCBI chr  X:70,425,218...70,432,120
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18328347)		 Ensembl
UniProt
RGD		 PMID:18328347 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Gpr21 G protein-coupled receptor 21 acts_upstream_of ISO
IEA		 MGI:5314799 (PMID:22653059)
GO_REF:0000107		 RGD
Ensembl		 PMID:22653059 GO_REF:0000107 NCBI chr 3:21,275,289...21,279,008
Ensembl chr 3:21,275,007...21,277,930 		JBrowse link
G Grb10 growth factor receptor bound protein 10 involved_in IDA
IBA		 PMID:11223174
GO_REF:0000033		 GO_Central PMID:11223174 GO_REF:0000033, RGD:8553640 NCBI chr14:90,708,653...90,816,399
Ensembl chr14:86,495,054...86,602,806 		JBrowse link
G Grb14 growth factor receptor bound protein 14 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:9748281 GO_REF:0000033, RGD:61620 NCBI chr 3:69,976,331...70,091,921
Ensembl chr 3:49,568,210...49,683,889 		JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO
IEA		 UniProtKB:P35568 (PMID:8388384)
(PMID:8649419), (PMID:8828504)
GO_REF:0000107		 RGD
Ensembl		 PMID:8388384 PMID:8649419 PMID:8828504 GO_REF:0000107 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Grb7 growth factor receptor bound protein 7 NOT|involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IBA
ISO		 GO_REF:0000033
(PMID:18285345)		 GO_Central
RGD		 PMID:18285345 GO_REF:0000033 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IBA
ISO		 GO_REF:0000033
(PMID:28057765)		 GO_Central
RGD		 PMID:28057765 GO_REF:0000033 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hmga1 high mobility group AT-hook 1 acts_upstream_of_or_within ISO MGI:1890077|MGI:3583805 (PMID:15924147), (PMID:22355763), (PMID:29867121) RGD PMID:15924147 PMID:22355763 PMID:29867121 NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:7829473) RGD PMID:7829473 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:22635104)
GO_REF:0000107		 RGD
Ensembl		 PMID:22635104 GO_REF:0000107 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor involved_in IMP
IBA		 PMID:19406747
GO_REF:0000033		 GO_Central PMID:19406747 GO_REF:0000033, RGD:13210538 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 involved_in ISO (PMID:20032056) RGD PMID:20032056 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 IEP RGD PMID:11784721 RGD:729306 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Ins1 insulin 1 involved_in ISO
IEA		 MGI:2181877 (PMID:20056832)
GO_REF:0000107		 RGD
Ensembl		 PMID:20056832 GO_REF:0000107 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ins2 insulin 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 MGI:2181878 (PMID:20056832)
UniProtKB:P01308 (PMID:14615391), (PMID:15792832), (PMID:19727662), (PMID:20455999), (PMID:8702995)
GO_REF:0000107
(PMID:3518947), (PMID:7782332)
(PMID:12805218)		 RGD
Ensembl		 PMID:3518947 PMID:7782332 PMID:8702995 PMID:12805218 PMID:14615391 More... GO_REF:0000107 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insr insulin receptor involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA
IEA
IEP
IDA		 UniProtKB:P01308 (PMID:19727662), (PMID:20455999), (PMID:3518947), (PMID:38056462), (PMID:6849137), (PMID:8440175)
GO_REF:0000033
MGI:99454 (PMID:18838380), (PMID:20032056), (PMID:23886629), (PMID:35248691), (PMID:8448209), (PMID:9038347)
MGI:1857204 (PMID:12488434)
GO_REF:0000107
PMID:19406747		 RGD
GO_Central
Ensembl		 PMID:3518947 PMID:6849137 PMID:8440175 PMID:8448209 PMID:9038347 More... GO_REF:0000033 GO_REF:0000107, RGD:1580595, RGD:13210538, RGD:11529553, RGD:2306052, RGD:14700925, RGD:1299201 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Insrr insulin receptor-related receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:175,553,244...175,572,676
Ensembl chr 2:173,255,414...173,274,800 		JBrowse link
G Irs1 insulin receptor substrate 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA
ISO		 PMID:17925406
GO_REF:0000002
GO_REF:0000033
MGI:2136643|MGI:96575 (PMID:33839150), (PMID:7526222), (PMID:7542745), (PMID:8649419), (PMID:9038347)
MGI:102548|MGI:1270849|MGI:1927343|MGI:87986|MGI:99454 (PMID:15249583), (PMID:9813005)
UniProtKB:P06213 (PMID:16516141), (PMID:16814735), (PMID:23401856), (PMID:38056462), (PMID:7537849), (PMID:7559478)		 InterPro
GO_Central
RGD		 PMID:7526222 PMID:7537849 PMID:7542745 PMID:7559478 PMID:8649419 More... GO_REF:0000002 GO_REF:0000033, RGD:8553954 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irs2 insulin receptor substrate 2 acts_upstream_of_or_within
involved_in		 IMP
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000002
GO_REF:0000033
MGI:2158686 (PMID:12488434), (PMID:9813005)
(PMID:7534300), (PMID:8649419)		 Ensembl
InterPro
GO_Central
RGD		 PMID:7534300 PMID:8649419 PMID:9813005 PMID:12488434 PMID:12891559 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1299201 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Irs3 insulin receptor substrate 3 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr12:24,689,930...24,692,068
Ensembl chr12:19,053,148...19,055,286 		JBrowse link
G Irs4 insulin receptor substrate 4 NAS RGD PMID:17720279 RGD:2301084 NCBI chr  X:110,132,490...110,148,473 JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20056832)		 Ensembl
RGD		 PMID:20056832 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:20889126) RGD PMID:20889126 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mtcl2 microtubule crosslinking factor 2 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:20813965)		 GO_Central
Ensembl
RGD		 PMID:20813965 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:166,089,141...166,161,043
Ensembl chr 3:145,675,443...145,740,871 		JBrowse link
G Mup4l1 major urinary protein 4 like 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:80,223,093...80,226,566
Ensembl chr 5:75,142,157...75,564,845 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase NOT|involved_in ISO (PMID:17983582) RGD PMID:17983582 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Ncoa5 nuclear receptor coactivator 5 acts_upstream_of ISO
IEA		 MGI:5581698 (PMID:24332041)
GO_REF:0000107		 RGD
Ensembl		 PMID:24332041 GO_REF:0000107 NCBI chr 3:153,736,420...153,769,838
Ensembl chr 3:153,736,420...153,769,553 		JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:28057765)		 Ensembl
RGD		 PMID:28057765 GO_REF:0000107 NCBI chr10:54,001,435...54,080,909
Ensembl chr10:53,516,491...53,570,907 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 IEP RGD PMID:11781314 RGD:625467 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Obp2a odorant binding protein 2A acts_upstream_of_or_within ISO MGI:2137691 (PMID:21135134) RGD PMID:21135134 NCBI chr 3:28,904,024...28,907,391
Ensembl chr 3:8,505,990...8,509,269 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22360721)		 UniProt
RGD		 PMID:22360721 GO_REF:0000024 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:19627255)
GO_REF:0000107
(PMID:21852536)		 UniProt
GO_Central
RGD
Ensembl		 PMID:19627255 PMID:21852536 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in IEA
ISO		 GO_REF:0000107
MGI:3795190 (PMID:18347057), (PMID:19047061)		 Ensembl
RGD		 PMID:18347057 PMID:19047061 GO_REF:0000107 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Phip pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO (PMID:11018022) RGD PMID:11018022 NCBI chr 8:92,656,890...92,771,098
Ensembl chr 8:83,781,465...83,894,283 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO
IEA		 MGI:3691486 (PMID:20197055)
GO_REF:0000107		 RGD
Ensembl		 PMID:20197055 GO_REF:0000107 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IMP
IBA
ISO
ISS		 GO_REF:0000033
(PMID:20348926), (PMID:7534300), (PMID:7542745)
GO_REF:0000024		 GO_Central
RGD
UniProt		 PMID:7534300 PMID:7542745 PMID:20348926 PMID:15161606 GO_REF:0000024 GO_REF:0000033, RGD:1625251 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 involved_in ISO
IEA
IBA		 (PMID:20348926)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:20348926 GO_REF:0000033 GO_REF:0000107 NCBI chr16:18,699,389...18,708,045
Ensembl chr16:18,665,457...18,674,065 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:7542745)
GO_REF:0000033		 RGD
GO_Central		 PMID:7542745 GO_REF:0000033 NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:129,701,229...129,772,583 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 acts_upstream_of_or_within ISO
IEA		 (PMID:15632081)
GO_REF:0000107		 RGD
Ensembl		 PMID:15632081 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15632081)		 UniProt
Ensembl
RGD		 PMID:15632081 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A acts_upstream_of_or_within ISO MGI:2445612 (PMID:14733908) RGD PMID:14733908 NCBI chr 3:138,103,261...138,212,835
Ensembl chr 3:117,650,183...117,759,728 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase involved_in IEA
ISO		 GO_REF:0000107
(PMID:20056832)		 Ensembl
RGD		 PMID:20056832 GO_REF:0000107 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 involved_in ISO
IEA		 (PMID:18242188)
GO_REF:0000107		 RGD
Ensembl		 PMID:18242188 GO_REF:0000107 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556 		JBrowse link
G Rhoq ras homolog family member Q involved_in ISO (PMID:11309621) RGD PMID:11309621 NCBI chr 6:13,368,499...13,403,929
Ensembl chr 1:106,622,141...106,623,699 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 acts_upstream_of_or_within ISO
IEA		 (PMID:10196204)
GO_REF:0000107		 RGD
Ensembl		 PMID:10196204 GO_REF:0000107 NCBI chr12:26,063,812...26,093,468
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Shc1 SHC adaptor protein 1 involved_in IDA
IBA
IMP		 PMID:17925406
GO_REF:0000033
PMID:7513704		 GO_Central PMID:17925406 PMID:7513704 GO_REF:0000033, RGD:8553954, RGD:8553924 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Sik2 salt-inducible kinase 2 acts_upstream_of_or_within ISO (PMID:12624099) RGD PMID:12624099 NCBI chr 8:60,121,913...60,221,707
Ensembl chr 8:51,225,543...51,325,415 		JBrowse link
G Slc2a8 solute carrier family 2 member 8 acts_upstream_of_or_within ISO
IEA		 (PMID:10860996)
GO_REF:0000107		 RGD
Ensembl		 PMID:10860996 GO_REF:0000107 NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:16,274,925...16,284,464 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 acts_upstream_of ISO
IEA		 (PMID:27703010)
GO_REF:0000107		 RGD
Ensembl		 PMID:27703010 GO_REF:0000107 NCBI chr15:51,786,517...51,833,260
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Smarcc1 SWI/SNF related BAF chromatin remodeling complex subunit C1 acts_upstream_of_or_within ISO
IEA		 (PMID:17074803)
GO_REF:0000107		 RGD
Ensembl		 PMID:17074803 GO_REF:0000107 NCBI chr 8:118,986,917...119,093,161
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3603205 (PMID:16127460)
GO_REF:0000033		 RGD
GO_Central		 PMID:16127460 GO_REF:0000033 NCBI chr10:82,848,525...82,885,201
Ensembl chr10:82,351,680...82,388,830 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9447983)		 UniProt
RGD		 PMID:9447983 GO_REF:0000024 NCBI chr 1:249,057,324...249,279,703
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in ISO
IEA		 (PMID:7829473), (PMID:8828504)
GO_REF:0000107		 RGD
Ensembl		 PMID:7829473 PMID:8828504 GO_REF:0000107 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 involved_in ISO (PMID:7829473) RGD PMID:7829473 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:88,042,966...88,156,692 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within ISO
IEA		 (PMID:17074803)
GO_REF:0000107		 RGD
Ensembl		 PMID:17074803 GO_REF:0000107 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Stxbp4 syntaxin binding protein 4 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:10394363)		 GO_Central
RGD		 PMID:10394363 GO_REF:0000033 NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663 		JBrowse link
G Wdr6 WD repeat domain 6 NAS RGD PMID:17720279 RGD:2301084 NCBI chr 8:109,268,079...109,274,504
Ensembl chr 8:109,268,079...109,274,499 		JBrowse link
G Zfp106 zinc finger protein 106 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:9507006)		 GO_Central
RGD		 PMID:9507006 GO_REF:0000033 NCBI chr 3:107,459,232...107,510,507
Ensembl chr 3:107,462,096...107,510,481 		JBrowse link
negative regulation of cellular response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO
IEA		 (PMID:19661063)
GO_REF:0000107		 RGD
Ensembl		 PMID:19661063 GO_REF:0000107 NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:23913704 RGD:13792716 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Lpl lipoprotein lipase IMP RGD PMID:25931001 RGD:13794384 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Mir15b microRNA 15b involved_in ISO (PMID:26179126) RGD PMID:26179126 NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:153,245,200...153,245,297 		JBrowse link
G Mir195 microRNA 195 involved_in ISO (PMID:25240198) RGD PMID:25240198 NCBI chr10:55,450,495...55,450,581
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:11387233) RGD PMID:11387233 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO (PMID:28973536) RGD PMID:28973536 NCBI chr10:52,243,664...52,256,250
Ensembl chr10:51,744,656...51,757,237 		JBrowse link
negative regulation of insulin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein IDA RGD PMID:2766355 RGD:632173 NCBI chr11:91,625,975...91,632,583
Ensembl chr11:78,117,918...78,145,999 		JBrowse link
G Ankrd26 ankyrin repeat domain containing 26 acts_upstream_of_or_within ISO MGI:3774418 (PMID:21842266) RGD PMID:21842266 NCBI chr 4:153,342,901...153,412,321
Ensembl chr 4:151,672,037...151,739,968 		JBrowse link
G Blvrb biliverdin reductase B involved_in ISO (PMID:38056462) RGD PMID:38056462 NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Cul7 cullin 7 involved_in ISO (PMID:18498745) RGD PMID:18498745 NCBI chr 9:21,816,703...21,830,344
Ensembl chr 9:14,319,108...14,332,741 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:17849011), (PMID:7830796) RGD PMID:7830796 PMID:17849011 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Fbxw8 F-box and WD repeat domain containing 8 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18498745)		 Ensembl
RGD		 PMID:18498745 GO_REF:0000107 NCBI chr12:44,087,375...44,177,985
Ensembl chr12:38,426,444...38,516,424 		JBrowse link
G Gpr21 G protein-coupled receptor 21 acts_upstream_of_or_within ISO
IEA		 MGI:5314799 (PMID:22653059)
GO_REF:0000107		 RGD
Ensembl		 PMID:22653059 GO_REF:0000107 NCBI chr 3:21,275,289...21,279,008
Ensembl chr 3:21,275,007...21,277,930 		JBrowse link
G Grb10 growth factor receptor bound protein 10 involved_in IBA
ISO		 GO_REF:0000033
(PMID:15664450)		 GO_Central
RGD		 PMID:15664450 GO_REF:0000033 NCBI chr14:90,708,653...90,816,399
Ensembl chr14:86,495,054...86,602,806 		JBrowse link
G Grb14 growth factor receptor bound protein 14 involved_in IDA
IBA
ISO
IEA
IMP		 GO_REF:0000033
(PMID:16246733)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:16246733 PMID:9748281 PMID:18657188 GO_REF:0000033 GO_REF:0000107, RGD:61620, RGD:2307023 NCBI chr 3:69,976,331...70,091,921
Ensembl chr 3:49,568,210...49,683,889 		JBrowse link
G Grb7 growth factor receptor bound protein 7 NOT|involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO
IDA		 (PMID:17569761)
PMID:8524413		 RGD PMID:17569761 PMID:8524413 RGD:8554844 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in IDA PMID:8524413 BHF-UCL PMID:8524413 RGD:8554844 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:16865359)		 Ensembl
RGD		 PMID:16865359 GO_REF:0000107 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F involved_in NAS PMID:26908121 ParkinsonsUK-UCL PMID:26908121 RGD:11059577 NCBI chr 1:192,620,891...192,700,681
Ensembl chr 1:183,190,480...183,270,276 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO
IEA
IBA		 (PMID:12556481)
GO_REF:0000107
(PMID:19250614)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:12556481 PMID:19250614 GO_REF:0000033 GO_REF:0000107 NCBI chr10:60,974,183...60,995,047
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:11692174 RGD:2312443 NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:156,183,059...156,197,500 		JBrowse link
G Irs1 insulin receptor substrate 1 involved_in IMP PMID:15069075 BHF-UCL PMID:15069075 RGD:8554248 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 involved_in ISO
IEA		 (PMID:18458160)
GO_REF:0000107		 RGD
Ensembl		 PMID:18458160 GO_REF:0000107 NCBI chr 1:232,381,720...232,500,834
Ensembl chr 1:222,877,622...223,074,514 		JBrowse link
G Lep leptin involved_in ISO (PMID:14677856) RGD PMID:14677856 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lonp1 lon peptidase 1, mitochondrial acts_upstream_of_or_within ISO
IEA		 (PMID:9813005)
GO_REF:0000107		 RGD
Ensembl		 PMID:9813005 GO_REF:0000107 NCBI chr 9:1,534,581...1,546,908
Ensembl chr 9:1,447,447...1,459,771 		JBrowse link
G Mir143 microRNA 143 acts_upstream_of_or_within ISO (PMID:21441927) RGD PMID:21441927 NCBI chr18:57,371,349...57,371,453
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Mir15b microRNA 15b involved_in ISO (PMID:26179126) RGD PMID:26179126 NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:153,245,200...153,245,297 		JBrowse link
G Mir195 microRNA 195 involved_in ISO (PMID:25240198) RGD PMID:25240198 NCBI chr10:55,450,495...55,450,581
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Mstn myostatin involved_in ISO
IEA		 (PMID:16182246)
GO_REF:0000107		 RGD
Ensembl		 PMID:16182246 GO_REF:0000107 NCBI chr 9:55,944,513...55,950,913
Ensembl chr 9:48,452,533...48,458,933 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IEA		 (PMID:21707536)
GO_REF:0000107		 RGD
Ensembl		 PMID:21707536 GO_REF:0000107 NCBI chr 8:109,897,723...109,958,247
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Ncl nucleolin acts_upstream_of_or_within ISO (PMID:9813005) RGD PMID:9813005 NCBI chr 9:94,447,559...94,456,083
Ensembl chr 9:86,998,019...87,008,136 		JBrowse link
G Ncoa5 nuclear receptor coactivator 5 acts_upstream_of_or_within ISO
IEA		 MGI:5581698 (PMID:24332041)
GO_REF:0000107		 RGD
Ensembl		 PMID:24332041 GO_REF:0000107 NCBI chr 3:153,736,420...153,769,838
Ensembl chr 3:153,736,420...153,769,553 		JBrowse link
G Nucb2 nucleobindin 2 IDA RGD PMID:22486620 RGD:9831186 NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:170,750,877...170,787,353 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO
IEA		 (PMID:19079291)
GO_REF:0000002
GO_REF:0000107		 RGD
InterPro
Ensembl		 PMID:19079291 GO_REF:0000002 GO_REF:0000107 NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31091439)		 UniProt
Ensembl
RGD		 PMID:31091439 GO_REF:0000024 GO_REF:0000107 NCBI chr17:86,405,080...86,576,597
Ensembl chr17:81,496,670...81,668,029 		JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in ISO
IEA
ISS		 (PMID:31091439)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:31091439 GO_REF:0000024 GO_REF:0000107 NCBI chr10:82,706,016...82,734,938
Ensembl chr10:82,701,098...82,734,938 		JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase type 2 gamma involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31091439)		 UniProt
Ensembl
RGD		 PMID:31091439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:64,905,322...64,920,380
Ensembl chr 7:63,020,000...63,035,078 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 IMP RGD PMID:20501641 RGD:6484547 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkca protein kinase C, alpha acts_upstream_of_or_within ISO MGI:2679305 (PMID:11923480) RGD PMID:11923480 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcb protein kinase C, beta involved_in IDA PMID:11714718 UniProt PMID:11714718 RGD:8553365 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:14583092), (PMID:18285345)
GO_REF:0000107		 RGD
Ensembl		 PMID:14583092 PMID:18285345 GO_REF:0000107 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkcq protein kinase C, theta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15364919)		 UniProt
Ensembl
RGD		 PMID:15364919 GO_REF:0000024 GO_REF:0000107 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Prkcz protein kinase C, zeta involved_in ISO (PMID:15069075) RGD PMID:15069075 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12612081), (PMID:20484139)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:12612081 PMID:20484139 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Ptpre protein tyrosine phosphatase, receptor type, E involved_in IDA
ISO		 PMID:15738637
(PMID:18006633)		 RGD PMID:18006633 PMID:15738637 RGD:8553759 NCBI chr 1:199,774,195...199,924,646
Ensembl chr 1:190,344,401...190,489,534 		JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F IMP RGD PMID:8557682 RGD:1642757 NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:131,742,754...131,810,023 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO
IEA		 (PMID:26063811)
GO_REF:0000107		 RGD
Ensembl		 PMID:26063811 GO_REF:0000107 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Rbx1 ring-box 1 involved_in ISO
IEA		 (PMID:18498745)
GO_REF:0000107		 RGD
Ensembl		 PMID:18498745 GO_REF:0000107 NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IMP RGD PMID:18073321 RGD:2298860 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 involved_in
acts_upstream_of_or_within		 IMP
ISO		 PMID:18952604
(PMID:18498745), (PMID:18952604)
MGI:102548|MGI:1927343|MGI:87986|MGI:99454 (PMID:15249583)		 RGD PMID:15249583 PMID:18498745 PMID:18952604 PMID:18952604 RGD:8554230 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 acts_upstream_of_or_within ISO
IEA		 MGI:102548|MGI:1270849|MGI:87986|MGI:99454 (PMID:15249583)
GO_REF:0000107		 RGD
Ensembl		 PMID:15249583 GO_REF:0000107 NCBI chr 1:210,880,824...210,887,556
Ensembl chr 1:201,451,265...201,458,078 		JBrowse link
G Slc27a4 solute carrier family 27 member 4 involved_in ISO
IEA		 (PMID:25603556)
GO_REF:0000107		 RGD
Ensembl		 PMID:25603556 GO_REF:0000107 NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:13,075,022...13,087,943 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO (PMID:15169905) RGD PMID:15169905 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 acts_upstream_of_or_within ISO (PMID:15169905) RGD PMID:15169905 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Tns2 tensin 2 involved_in ISO
IEA
IBA		 (PMID:23401856)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23401856 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:135,108,401...135,126,505
Ensembl chr 7:133,206,364...133,247,888 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12791994)		 Ensembl
RGD		 PMID:12791994 GO_REF:0000107 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trim72 tripartite motif containing 72 acts_upstream_of_or_within ISO
IEA		 (PMID:23965929)
GO_REF:0000107		 RGD
Ensembl		 PMID:23965929 GO_REF:0000107 NCBI chr 1:192,044,220...192,052,080
Ensembl chr 1:182,613,712...182,621,606 		JBrowse link
G Tsc2 TSC complex subunit 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Tsc2_v1 TSC complex subunit 2, variant 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Tsc2_v2 TSC complex subunit 2, variant 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Ybx1 Y box binding protein 1 IMP RGD PMID:12554649 RGD:727501 NCBI chr 5:138,167,444...138,188,155
Ensembl chr 5:132,882,145...132,898,862 		JBrowse link
G Zfp592 zinc finger protein 592 acts_upstream_of_or_within ISO
IEA		 (PMID:9813005)
GO_REF:0000107		 RGD
Ensembl		 PMID:9813005 GO_REF:0000107 NCBI chr 1:144,355,227...144,411,686
Ensembl chr 1:134,967,783...135,002,443 		JBrowse link
positive regulation of cellular response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qtnf9 C1q and TNF related 9 acts_upstream_of_or_within ISO
IEA		 (PMID:23842676)
GO_REF:0000107		 RGD
Ensembl		 PMID:23842676 GO_REF:0000107 NCBI chr15:39,083,883...39,099,167
Ensembl chr15:34,911,286...34,922,980 		JBrowse link
G Echdc3 enoyl CoA hydratase domain containing 3 involved_in ISO
IEA		 (PMID:31010960)
GO_REF:0000107		 RGD
Ensembl		 PMID:31010960 GO_REF:0000107 NCBI chr17:76,980,112...77,002,934
Ensembl chr17:72,070,668...72,093,516 		JBrowse link
G Esrra estrogen related receptor, alpha IMP RGD PMID:20215575 RGD:10401858 NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:204,104,101...204,114,268 		JBrowse link
G Myo1c myosin 1C acts_upstream_of_or_within IMP
ISO
IEA		 (PMID:12490950)
GO_REF:0000107		 RGD
Ensembl		 PMID:12490950 PMID:22918957 GO_REF:0000107, RGD:11073622 NCBI chr10:60,996,642...61,019,022
Ensembl chr10:60,498,280...60,520,752 		JBrowse link
G Myo5a myosin VA IMP RGD PMID:24478457 RGD:11532776 NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IMP RGD PMID:24085037 RGD:13208948 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
positive regulation of insulin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 IMP RGD PMID:18394428 RGD:2317907 NCBI chr13:48,411,438...48,431,251
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Agt angiotensinogen IDA RGD PMID:24184594 RGD:11039409 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G C1qtnf12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:22275362)		 GO_Central
Ensembl
RGD		 PMID:22275362 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:171,833,854...171,838,229
Ensembl chr 5:166,551,628...166,556,003 		JBrowse link
G Erfe erythroferrone involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:99,404,512...99,412,383
Ensembl chr 9:91,956,977...91,964,846 		JBrowse link
G Gkap1 G kinase anchoring protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25586176)		 UniProt
RGD		 PMID:25586176 GO_REF:0000024 NCBI chr17:6,383,963...6,423,684
Ensembl chr17:6,383,963...6,423,679 		JBrowse link
G Igf2 insulin-like growth factor 2 involved_in ISO
IBA		 (PMID:11500939)
GO_REF:0000033		 RGD
GO_Central		 PMID:11500939 GO_REF:0000033 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:7513704)
(PMID:7688386)		 RGD PMID:7513704 PMID:7688386 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Irs1 insulin receptor substrate 1 involved_in ISO
IMP		 (PMID:7493946)
PMID:18285345		 RGD PMID:7493946 PMID:18285345 RGD:8553881 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Lep leptin IDA RGD PMID:20977462 RGD:5128575 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate IMP RGD PMID:19252893 RGD:9685323 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:25034891 RGD:13204821 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16446356)		 Ensembl
RGD		 PMID:16446356 GO_REF:0000107 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 acts_upstream_of_or_within ISO (PMID:24931609) RGD PMID:24931609 NCBI chr13:45,897,275...45,926,491
Ensembl chr13:43,345,115...43,370,229 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IMP RGD PMID:24085037 RGD:13208948 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Osbpl8 oxysterol binding protein-like 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21441927)
GO_REF:0000107
(PMID:23812417)		 RGD
Ensembl		 PMID:21441927 PMID:23812417 GO_REF:0000107 NCBI chr 7:48,483,259...48,636,151
Ensembl chr 7:46,596,983...46,749,888 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:25199455 RGD:11533947 NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Prkcz protein kinase C, zeta involved_in IMP PMID:9374484 UniProt PMID:9374484 RGD:8553908 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in ISO
IEA		 (PMID:7493946)
GO_REF:0000107		 RGD
Ensembl		 PMID:7493946 GO_REF:0000107 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Serpina12 serpin family A member 12 acts_upstream_of_or_within ISO
IEA		 MGI:5568548 (PMID:22837305)
GO_REF:0000107		 RGD
Ensembl		 PMID:22837305 GO_REF:0000107 NCBI chr 6:128,717,334...128,732,049
Ensembl chr 6:122,952,552...122,967,271 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:21241768)
GO_REF:0000107		 RGD
Ensembl		 PMID:21241768 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Snx5 sorting nexin 5 involved_in ISO
IEA		 (PMID:25825816)
GO_REF:0000107		 RGD
Ensembl		 PMID:25825816 GO_REF:0000107 NCBI chr 3:152,075,258...152,094,508
Ensembl chr 3:131,621,880...131,641,192 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11001060)		 UniProt
RGD		 PMID:11001060 GO_REF:0000024 NCBI chr 1:249,057,324...249,279,703
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO
IEA		 (PMID:27322061)
GO_REF:0000107		 RGD
Ensembl		 PMID:27322061 GO_REF:0000107 NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IDA RGD PMID:14985360 RGD:1581139 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tsc2 TSC complex subunit 2 acts_upstream_of_or_within ISO MGI:1270849|MGI:1927343 (PMID:15249583) RGD PMID:15249583 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO
IEA		 (PMID:29420538)
GO_REF:0000107		 RGD
Ensembl		 PMID:29420538 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
regulation of cellular response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISO
IEA
ISS		 (PMID:29104511)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29104511 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Cul3 cullin 3 involved_in ISO
IEA		 (PMID:27708159)
GO_REF:0000107		 RGD
Ensembl		 PMID:27708159 GO_REF:0000107 NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18328347)		 UniProt
Ensembl
RGD		 PMID:18328347 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Kbtbd2 kelch repeat and BTB domain containing 2 involved_in ISO
IEA		 (PMID:27708159)
GO_REF:0000107		 RGD
Ensembl		 PMID:27708159 GO_REF:0000107 NCBI chr 4:87,358,133...87,380,399
Ensembl chr 4:86,027,947...86,050,211 		JBrowse link
G Uso1 USO1 vesicle transport factor acts_upstream_of_or_within ISO
IEA		 (PMID:15800058)
GO_REF:0000107		 RGD
Ensembl		 PMID:15800058 GO_REF:0000107 NCBI chr14:16,150,921...16,216,389
Ensembl chr14:15,866,638...15,932,171 		JBrowse link
regulation of insulin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ffar3 free fatty acid receptor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24748202)		 UniProt
RGD		 PMID:24748202 GO_REF:0000024 NCBI chr 1:95,232,804...95,234,144
Ensembl chr 1:86,104,920...86,106,849 		JBrowse link
G Fut7 fucosyltransferase 7 involved_in ISO (PMID:17229154) RGD PMID:17229154 NCBI chr 3:28,635,913...28,640,407
Ensembl chr 3:8,239,384...8,242,260 		JBrowse link
G Mir494 microRNA 494 acts_upstream_of_or_within ISO (PMID:24349514) RGD PMID:24349514 NCBI chr 6:134,550,115...134,550,197
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mzb1 marginal zone B and B1 cell-specific protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21688198)		 UniProt
Ensembl
RGD		 PMID:21688198 GO_REF:0000024 GO_REF:0000107 NCBI chr18:27,513,087...27,515,148
Ensembl chr18:27,239,001...27,241,094 		JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 involved_in ISO (PMID:26205492) RGD PMID:26205492 NCBI chr13:45,897,275...45,926,491
Ensembl chr13:43,345,115...43,370,229 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO		 GO_REF:0000107
(PMID:18288188)		 Ensembl
RGD		 PMID:18288188 GO_REF:0000107 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 IMP RGD PMID:12941932 RGD:1625241 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 involved_in ISO (PMID:18242188) RGD PMID:18242188 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556 		JBrowse link
G Rbm14 RNA binding motif protein 14 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:211,476,298...211,535,077
Ensembl chr 1:202,078,287...202,105,665
Ensembl chr 1:202,078,287...202,105,665 		JBrowse link
G Rbm4 RNA binding motif protein 4 acts_upstream_of_or_within ISO (PMID:23129807) RGD PMID:23129807 NCBI chr 1:211,507,845...211,516,907
Ensembl chr 1:202,085,279...202,105,380 		JBrowse link
G Sesn3 sestrin 3 involved_in ISO (PMID:25377878) RGD PMID:25377878 NCBI chr 8:19,415,307...19,470,943
Ensembl chr 8:11,133,678...11,185,842 		JBrowse link
G Sik2 salt-inducible kinase 2 involved_in ISO (PMID:12624099) RGD PMID:12624099 NCBI chr 8:60,121,913...60,221,707
Ensembl chr 8:51,225,543...51,325,415 		JBrowse link
G Tsc2 TSC complex subunit 2 acts_upstream_of_or_within ISO MGI:1857938 (PMID:12403809) RGD PMID:12403809 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Vwa2 von Willebrand factor A domain containing 2 involved_in ISO (PMID:15699509) RGD PMID:15699509 NCBI chr 1:255,922,263...255,963,920
Ensembl chr 1:255,923,541...255,963,934 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    response to stimulus 11081
      response to endogenous stimulus 2059
        response to hormone 1376
          response to peptide hormone 696
            response to insulin 400
              cellular response to insulin stimulus 294
                glucose import in response to insulin stimulus 6
                insulin receptor signaling pathway + 155
                negative regulation of cellular response to insulin stimulus + 62
                positive regulation of cellular response to insulin stimulus + 35
                regulation of cellular response to insulin stimulus + 98
paths to the root