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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of natural killer cell activation
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Accession:GO:0032816 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of natural killer cell activation.
Synonyms:exact_synonym: positive regulation of NK cell activation;   up regulation of natural killer cell activation;   upregulation of natural killer cell activation
 narrow_synonym: activation of natural killer cell activation;   stimulation of natural killer cell activation


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positive regulation of natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857021 (PMID:7089489) 		Ensembl
RGD		 PMID:7089489 GO_REF:0000107 NCBI chr 1:88,283,864...88,286,244
Ensembl chr 1:88,280,115...88,294,060 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856982 (PMID:7089489) 		Ensembl
RGD		 PMID:7089489 GO_REF:0000107 NCBI chr 3:130,269,979...130,280,109
Ensembl chr 3:130,268,442...130,281,360 		JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO MGI:1856712 (PMID:7089489) RGD PMID:7089489 NCBI chr 1:251,500,427...251,526,529
Ensembl chr 1:251,500,427...251,526,739 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA 		(PMID:1674604)
GO_REF:0000107 		RGD
Ensembl		 PMID:1674604 GO_REF:0000107 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA 		(PMID:1674604)
GO_REF:0000107 		RGD
Ensembl		 PMID:1674604 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO MGI:1855968 (PMID:7089489) RGD PMID:7089489 NCBI chr17:93,225,509...93,427,650
Ensembl chr17:93,225,540...93,427,650 		JBrowse link
G Mir130a microRNA 130a involved_in ISO (PMID:31883616) RGD PMID:31883616 NCBI chr 3:90,229,228...90,229,315 JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21957144) 		Ensembl
RGD		 PMID:21957144 GO_REF:0000107 NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:124,622,313...124,684,434 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:37264229) RGD PMID:37264229 NCBI chr20:4,872,720...4,876,425 JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:3701472 (PMID:21059856) RGD PMID:21059856 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,172,963...1,196,892 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in IBA
ISO 		GO_REF:0000033
(PMID:9647200) 		GO_Central
RGD		 PMID:9647200 GO_REF:0000033 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:94,800,117...94,804,299 		JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:3,506,106...3,527,982 JBrowse link
positive regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl Axl receptor tyrosine kinase involved_in ISO (PMID:18840707) RGD PMID:18840707 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009 		JBrowse link
G Gas6 growth arrest specific 6 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:18840707)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:18840707 GO_REF:0000024 GO_REF:0000107 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088 		JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1931086|MGI:2136897 (PMID:14607906), (PMID:17318811) 		Ensembl
RGD		 PMID:14607906 PMID:17318811 GO_REF:0000107 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1934016 (PMID:14607906) 		Ensembl
RGD		 PMID:14607906 GO_REF:0000107 NCBI chr17:71,712,141...71,742,072
Ensembl chr17:71,712,141...71,742,149 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) RGD PMID:14764669 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21957144) 		Ensembl
RGD		 PMID:21957144 GO_REF:0000107 NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:124,622,313...124,684,434 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857249 (PMID:9841920) 		Ensembl
RGD		 PMID:9841920 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2181592 (PMID:9841920) 		Ensembl
RGD		 PMID:9841920 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990 		JBrowse link
G Tox thymocyte selection-associated high mobility group box acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3773716 (PMID:20818394) 		Ensembl
RGD		 PMID:20818394 GO_REF:0000107 NCBI chr 5:24,672,487...24,968,754
Ensembl chr 5:24,672,487...24,968,754 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:22753936) 		Ensembl
RGD		 PMID:22753936 GO_REF:0000107 NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:100,838,714...100,852,643 		JBrowse link
positive regulation of natural killer cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:15905190) RGD PMID:15905190 NCBI chr13:86,583,727...86,606,902
Ensembl chr13:86,584,826...86,616,009 		JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:9916693) RGD PMID:9916693 NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand IDA RGD PMID:16528542 RGD:11049499 NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:104,749,983...104,757,038 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA 		(PMID:19088061)
GO_REF:0000107 		RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:14607906) 		Ensembl
RGD		 PMID:14607906 GO_REF:0000107 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il18 interleukin 18 involved_in ISO
IEA 		(PMID:19088061)
GO_REF:0000107 		RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO
IEA 		(PMID:19088061)
GO_REF:0000107 		RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO
IEA 		(PMID:19088061)
GO_REF:0000107 		RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,872,720...4,876,425 JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2181592 (PMID:9841920) 		Ensembl
RGD		 PMID:9841920 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:27,916,496...27,943,278 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2920
      leukocyte activation 1068
        lymphocyte activation 867
          natural killer cell activation 100
            positive regulation of natural killer cell activation 28
              positive regulation of natural killer cell differentiation + 10
              positive regulation of natural killer cell proliferation + 11
Path 2
Term Annotations click to browse term
  biological_process 19315
    biological regulation 13355
      regulation of biological process 12936
        regulation of multicellular organismal process 3395
          positive regulation of multicellular organismal process 1933
            positive regulation of cell activation 385
              positive regulation of leukocyte activation 361
                positive regulation of lymphocyte activation 321
                  positive regulation of natural killer cell activation 28
                    positive regulation of natural killer cell differentiation + 10
                    positive regulation of natural killer cell proliferation + 11
paths to the root