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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of natural killer cell activation
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Accession:GO:0032815 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.
Synonyms:exact_synonym: down regulation of natural killer cell activation;   downregulation of natural killer cell activation;   negative regulation of NK cell activation
 narrow_synonym: inhibition of natural killer cell activation



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negative regulation of natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec12a C-type lectin domain family 12, member A involved_in ISO (PMID:15238421), (PMID:31269448)
(PMID:31269448)
RGD PMID:15238421 PMID:31269448 NCBI chr 4:162,798,125...162,816,757 JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (PMID:15199160), (PMID:16439675) RGD PMID:15199160 PMID:16439675 NCBI chr14:71,923,894...72,101,180 JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:16439675) RGD PMID:16439675 NCBI chr 5:150,473,767...150,503,524 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:25337993) RGD PMID:25337993 NCBI chr10:30,882,484...30,914,018 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,405,044...64,428,249 JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:78,372,798...78,398,932 JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:12516630) RGD PMID:12516630 NCBI chr15:82,258,243...82,427,546 JBrowse link
G Rhbdd3 rhomboid domain containing 3 acts_upstream_of_or_within ISO MGI:5516031 (PMID:23610400) RGD PMID:23610400 NCBI chr14:79,994,111...80,000,294 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:37264229) RGD PMID:37264229 NCBI chr20:4,870,939...4,910,183 JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2670590 (PMID:20709292)
Ensembl
RGD
PMID:20709292 GO_REF:0000107 NCBI chr 1:78,531,815...78,537,001 JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 acts_upstream_of_or_within ISO MGI:5297105 (PMID:20709292) RGD PMID:20709292 NCBI chr 7:11,418,674...11,432,162 JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 acts_upstream_of_or_within ISO MGI:5297106 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:177,479,693...177,490,769 JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 acts_upstream_of_or_within ISO MGI:5297107 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:176,202,654...176,322,859 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    immune system process 3112
      leukocyte activation 1070
        lymphocyte activation 867
          natural killer cell activation 102
            negative regulation of natural killer cell activation 13
              negative regulation of natural killer cell differentiation + 4
              negative regulation of natural killer cell proliferation + 0
Path 2
Term Annotations click to browse term
  biological_process 20534
    biological regulation 13821
      regulation of biological process 13375
        regulation of multicellular organismal process 3340
          negative regulation of multicellular organismal process 1353
            negative regulation of cell activation 241
              negative regulation of leukocyte activation 221
                negative regulation of lymphocyte activation 190
                  negative regulation of natural killer cell activation 13
                    negative regulation of natural killer cell differentiation + 4
                    negative regulation of natural killer cell proliferation + 0
paths to the root