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ONTOLOGY REPORT - ANNOTATIONS

Term:stereocilium
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Accession:GO:0032420 term browser browse the term
Definition:An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
Synonyms:never_in_taxon: NCBITaxon:4751 ! Fungi

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stereocilium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrv1 adhesion G protein-coupled receptor V1 is_active_in ISO (PMID:26754646) RGD
MGI		 PMID:16301216 PMID:26754646 RGD:8548636 NCBI chrNW_004936469:8,653,031...9,209,840 JBrowse link
G Ankrd24 ankyrin repeat domain 24 located_in ISO (PMID:35175278) UniProt PMID:35175278 NCBI chrNW_004936588:2,403,454...2,419,279 JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:6,652,240...6,712,960
Ensembl chrNW_004936497:6,652,185...6,713,034 		JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:8,785,914...8,810,490
Ensembl chrNW_004936475:8,785,154...8,810,541 		JBrowse link
G Calb1 calbindin 1 ISO RGD PMID:16120789 RGD:7175527 NCBI chrNW_004936544:3,858,344...3,881,985
Ensembl chrNW_004936544:3,858,344...3,882,106 		JBrowse link
G Calb2 calbindin 2 ISO RGD PMID:16120789 RGD:7175527 NCBI chrNW_004936475:22,344,416...22,372,015
Ensembl chrNW_004936475:22,341,822...22,372,609 		JBrowse link
G Cib2 calcium and integrin binding family member 2 located_in IEA TreeGrafter
Ensembl
UniProt		 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:36,859,018...36,879,170
Ensembl chrNW_004936471:36,859,018...36,878,878 		JBrowse link
G Clic5 chloride intracellular channel 5 located_in ISO (PMID:17021174) MGI PMID:17021174 NCBI chrNW_004936476:14,234,447...14,381,582
Ensembl chrNW_004936476:14,283,006...14,381,634 		JBrowse link
G Clrn1 clarin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936758:1,250,831...1,286,016
Ensembl chrNW_004936758:1,250,769...1,285,376 		JBrowse link
G Dock4 dedicator of cytokinesis 4 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936795:823,730...1,262,584
Ensembl chrNW_004936795:1,009,634...1,260,358 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936587:1,785,721...1,951,474
Ensembl chrNW_004936587:1,785,303...1,951,332 		JBrowse link
G Espn espin located_in IEA Ensembl
UniProt		 GO_REF:0000044 GO_REF:0000107 NCBI chrNW_004936623:1,220,435...1,249,743
Ensembl chrNW_004936623:1,220,593...1,248,993 		JBrowse link
G Espnl espin like located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004936525:352,389...380,214
Ensembl chrNW_004936525:352,389...380,214 		JBrowse link
G Fscn2 fascin actin-bundling protein 2, retinal located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:5,184,133...5,195,340
Ensembl chrNW_004936594:5,184,628...5,191,985 		JBrowse link
G Grxcr1 glutaredoxin and cysteine rich domain containing 1 located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936482:9,981,410...10,087,222
Ensembl chrNW_004936482:9,981,356...10,087,222 		JBrowse link
G Ift20 intraflagellar transport 20 located_in ISO (PMID:25605782) MGI PMID:25605782 NCBI chrNW_004936538:4,484,484...4,491,688 JBrowse link
G LOC101969963 cadherin-23 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:7,078,874...7,285,361
Ensembl chrNW_004936521:7,010,360...7,340,842 		JBrowse link
G LOC101976443 lipoxygenase homology PLAT domains 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936517:271,909...409,818
Ensembl chrNW_004936517:271,909...409,691 		JBrowse link
G Minar2 membrane integral NOTCH2 associated receptor 2 is_active_in
located_in		 ISO
IEA		 (PMID:35727972) MGI
Ensembl		 PMID:35727972 GO_REF:0000107 NCBI chrNW_004936504:2,830,286...2,847,785
Ensembl chrNW_004936504:2,830,236...2,847,847 		JBrowse link
G Morn4 MORN repeat containing 4 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004936636:2,089,013...2,099,651
Ensembl chrNW_004936636:2,089,062...2,099,614 		JBrowse link
G Mpp1 MAGUK p55 scaffold protein 1 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004936927:147,448...170,435
Ensembl chrNW_004936927:147,282...170,575 		JBrowse link
G Myo15a myosin XVA located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936741:1,669,680...1,724,929
Ensembl chrNW_004936741:1,669,680...1,723,891 		JBrowse link
G Myo1c myosin IC located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:7,614,985...7,639,603
Ensembl chrNW_004936538:7,611,008...7,639,581 		JBrowse link
G Myo7a myosin VIIA located_in
is_active_in		 IEA
ISO		 (PMID:26754646) Ensembl
MGI		 PMID:26754646 GO_REF:0000107 NCBI chrNW_004936498:5,758,572...5,824,526
Ensembl chrNW_004936498:5,751,779...5,824,378 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:119,808...136,620
Ensembl chrNW_004936594:119,770...136,789 		JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 located_in ISO (PMID:24920589) MGI PMID:24920589 NCBI chrNW_004936694:2,000,977...2,006,102
Ensembl chrNW_004936694:2,000,854...2,006,567 		JBrowse link
G Pafah1b1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:8,612,142...8,693,698
Ensembl chrNW_004936538:8,612,049...8,694,015 		JBrowse link
G Pcdh15 protocadherin related 15 located_in
is_active_in		 IEA
ISO		 (PMID:26754646) Ensembl
MGI
InterPro		 PMID:26754646 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936910:233,800...602,145
Ensembl chrNW_004936910:141,917...602,089 		JBrowse link
G Pdzd7 PDZ domain containing 7 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936600:4,660,211...4,678,911
Ensembl chrNW_004936600:4,661,332...4,678,107 		JBrowse link
G Piezo1 piezo type mechanosensitive ion channel component 1 (Er blood group) located_in ISO (PMID:38228630) UniProt PMID:38228630 NCBI chrNW_004936641:932,291...980,440
Ensembl chrNW_004936641:932,577...980,233 		JBrowse link
G Piezo2 piezo type mechanosensitive ion channel component 2 located_in ISO (PMID:38228630) UniProt PMID:38228630 NCBI chrNW_004936626:802,415...1,141,260
Ensembl chrNW_004936626:802,490...1,140,082 		JBrowse link
G Pls1 plastin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936540:4,205,871...4,323,121
Ensembl chrNW_004936540:4,205,844...4,323,120 		JBrowse link
G Pls3 plastin 3 ISO RGD PMID:12378542 RGD:731234 NCBI chrNW_004936499:246,042...335,440
Ensembl chrNW_004936499:246,042...335,440 		JBrowse link
G Prom1 prominin 1 located_in ISO (PMID:15316084) MGI PMID:15316084 NCBI chrNW_004936477:11,878,261...12,017,228
Ensembl chrNW_004936477:11,878,012...12,018,177 		JBrowse link
G Pvalb parvalbumin ISO RGD PMID:16120789 RGD:7175527 NCBI chrNW_004936492:4,048,459...4,064,024
Ensembl chrNW_004936492:4,048,470...4,064,019 		JBrowse link
G Rdx radixin located_in ISO (PMID:17021174) MGI PMID:17021174 NCBI chrNW_004936612:3,992,542...4,060,598
Ensembl chrNW_004936612:3,992,542...4,040,315 		JBrowse link
G Rhoc ras homolog family member C located_in ISO (PMID:27269051) UniProt PMID:27269051 NCBI chrNW_004936690:1,255,126...1,258,288 JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936671:1,064,937...1,232,985
Ensembl chrNW_004936671:1,051,742...1,093,021 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 ISO RGD PMID:16301216 RGD:8548636 NCBI chrNW_004936473:18,550,489...18,645,470
Ensembl chrNW_004936473:18,550,484...18,645,628 		JBrowse link
G Stx4 syntaxin 4 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:13,401,095...13,408,316
Ensembl chrNW_004936501:13,401,989...13,408,325 		JBrowse link
G Tmc1 transmembrane channel like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:8,669,465...8,826,340
Ensembl chrNW_004936503:8,719,540...8,825,795 		JBrowse link
G Tmc2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:16,051,974...16,122,899
Ensembl chrNW_004936485:16,051,974...16,109,978 		JBrowse link
G Tprn taperin located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:786,569...794,713
Ensembl chrNW_004936669:786,808...794,155 		JBrowse link
G Tspear thrombospondin type laminin G domain and EAR repeats located_in IEA Ensembl
UniProt		 GO_REF:0000044 GO_REF:0000107 NCBI chrNW_004936778:1,576,580...1,660,344
Ensembl chrNW_004936778:1,478,617...1,660,331 		JBrowse link
G Ush1c USH1 protein network component harmonin located_in
is_active_in		 ISO (PMID:12485990), (PMID:20016102)
(PMID:26754646)		 RGD
MGI		 PMID:12485990 PMID:16301216 PMID:20016102 PMID:26754646 RGD:8548636 NCBI chrNW_004936528:1,552,175...1,594,740
Ensembl chrNW_004936528:1,552,289...1,594,801 		JBrowse link
G Ush2a usherin ISO hair cell RGD PMID:16301216 RGD:8548636 NCBI chrNW_004936628:2,123,917...2,859,958
Ensembl chrNW_004936628:2,123,957...2,858,872 		JBrowse link
G Whrn whirlin located_in ISO
IEA		 RGD
Ensembl		 PMID:16434480 GO_REF:0000107 RGD:1600128 NCBI chrNW_004936487:3,668,465...3,748,234
Ensembl chrNW_004936487:3,669,104...3,748,238 		JBrowse link
G Zswim6 zinc finger SWIM-type containing 6 located_in ISO (PMID:25105228) MGI PMID:25105228 NCBI chrNW_004936480:7,049,499...7,239,035
Ensembl chrNW_004936480:7,051,334...7,239,677 		JBrowse link
stereocilium base term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clic5 chloride intracellular channel 5 located_in ISO PMID:24285636
(PMID:37952086)		 UniProt PMID:24285636 PMID:37952086 RGD:401966878 NCBI chrNW_004936476:14,234,447...14,381,582
Ensembl chrNW_004936476:14,283,006...14,381,634 		JBrowse link
G Grxcr2 glutaredoxin and cysteine rich domain containing 2 located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936504:8,775,832...8,789,254
Ensembl chrNW_004936504:8,775,855...8,788,076 		JBrowse link
G Myo7a myosin VIIA located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:5,758,572...5,824,526
Ensembl chrNW_004936498:5,751,779...5,824,378 		JBrowse link
G Pjvk pejvakin located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936509:7,670,557...7,677,480
Ensembl chrNW_004936509:7,670,325...7,677,581 		JBrowse link
G Ptprq protein tyrosine phosphatase receptor type Q located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936698:1,372,604...1,569,905
Ensembl chrNW_004936698:1,372,607...1,569,905 		JBrowse link
G Rdx radixin located_in ISO (PMID:24285636), (PMID:30159668) UniProt PMID:24285636 PMID:30159668 NCBI chrNW_004936612:3,992,542...4,060,598
Ensembl chrNW_004936612:3,992,542...4,040,315 		JBrowse link
G Tprn taperin located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936669:786,569...794,713
Ensembl chrNW_004936669:786,808...794,155 		JBrowse link
G Triobp TRIO and F-actin binding protein located_in ISO (PMID:28209736) MGI PMID:28209736 NCBI chrNW_004936492:3,337,791...3,390,420 JBrowse link
stereocilium coat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkhd1l1 PKHD1 like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:35,484,857...35,624,504
Ensembl chrNW_004936470:35,484,995...35,624,465 		JBrowse link
stereocilium membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1b calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:10408625 RGD:11556226 (All species) (All species) NCBI chrNW_004936669:133,488...308,623
Ensembl chrNW_004936669:133,698...308,488 		JBrowse link
G Myo1c myosin IC located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004936538:7,614,985...7,639,603
Ensembl chrNW_004936538:7,611,008...7,639,581 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004936671:1,064,937...1,232,985
Ensembl chrNW_004936671:1,051,742...1,093,021 		JBrowse link
G Ush2a usherin located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936628:2,123,917...2,859,958
Ensembl chrNW_004936628:2,123,957...2,858,872 		JBrowse link
stereocilium shaft term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fchsd2 FCH and double SH3 domains 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:2,089,069...2,344,007
Ensembl chrNW_004936498:2,086,282...2,344,708 		JBrowse link
G Grxcr2 glutaredoxin and cysteine rich domain containing 2 located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936504:8,775,832...8,789,254
Ensembl chrNW_004936504:8,775,855...8,788,076 		JBrowse link
stereocilium tip term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam16 CEA cell adhesion molecule 16, tectorial membrane component located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:1,390,737...1,396,472
Ensembl chrNW_004936706:1,391,814...1,396,571 		JBrowse link
G Coro1a coronin 1A is_active_in ISO (PMID:26754646) MGI PMID:26754646 NCBI chrNW_004936501:12,338,542...12,344,236
Ensembl chrNW_004936501:12,338,542...12,344,265 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936587:1,785,721...1,951,474
Ensembl chrNW_004936587:1,785,303...1,951,332 		JBrowse link
G Eps8l2 EPS8 signaling adaptor L2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936888:506,144...523,280
Ensembl chrNW_004936888:506,138...523,302 		JBrowse link
G Espn espin located_in
is_active_in		 ISO (PMID:22264607), (PMID:26754646)
(PMID:26754646)		 MGI PMID:22264607 PMID:26754646 NCBI chrNW_004936623:1,220,435...1,249,743
Ensembl chrNW_004936623:1,220,593...1,248,993 		JBrowse link
G Espnl espin like located_in
is_active_in		 IEA
ISO		 (PMID:26754646) Ensembl
MGI		 PMID:26754646 GO_REF:0000107 NCBI chrNW_004936525:352,389...380,214
Ensembl chrNW_004936525:352,389...380,214 		JBrowse link
G Homer2 homer scaffold protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:17,500,962...17,634,804
Ensembl chrNW_004936483:17,507,533...17,539,105 		JBrowse link
G Lhfpl5 LHFPL tetraspan subfamily member 5 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:23,479,939...23,491,611
Ensembl chrNW_004936476:23,482,756...23,491,811 		JBrowse link
G LOC101969963 cadherin-23 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:7,078,874...7,285,361
Ensembl chrNW_004936521:7,010,360...7,340,842 		JBrowse link
G LOC101972535 dual specificity protein phosphatase CDC14A located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936748:479,026...612,554
Ensembl chrNW_004936748:479,503...623,126 		JBrowse link
G Morn4 MORN repeat containing 4 located_in
is_active_in		 IEA
ISO		 (PMID:26754646) Ensembl
MGI		 PMID:26754646 GO_REF:0000107 NCBI chrNW_004936636:2,089,013...2,099,651
Ensembl chrNW_004936636:2,089,062...2,099,614 		JBrowse link
G Myo3a myosin IIIA is_active_in
located_in		 ISO
IEA		 (PMID:26754646) MGI
TreeGrafter		 PMID:26754646 GO_REF:0000118 NCBI chrNW_004936484:1,509,248...1,723,717
Ensembl chrNW_004936484:1,509,235...1,723,554 		JBrowse link
G Myo3b myosin IIIB is_active_in
located_in		 ISO
IEA		 (PMID:26754646) MGI
TreeGrafter		 PMID:26754646 GO_REF:0000118 NCBI chrNW_004936509:615,958...1,074,742
Ensembl chrNW_004936509:615,898...1,074,870 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:119,808...136,620
Ensembl chrNW_004936594:119,770...136,789 		JBrowse link
G Pdzd7 PDZ domain containing 7 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936600:4,660,211...4,678,911
Ensembl chrNW_004936600:4,661,332...4,678,107 		JBrowse link
G Pkhd1l1 PKHD1 like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:35,484,857...35,624,504
Ensembl chrNW_004936470:35,484,995...35,624,465 		JBrowse link
G Strc stereocilin located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:6,760,289...6,777,425
Ensembl chrNW_004936471:6,760,294...6,777,425 		JBrowse link
G Tmc1 transmembrane channel like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:8,669,465...8,826,340
Ensembl chrNW_004936503:8,719,540...8,825,795 		JBrowse link
G Tmc2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:16,051,974...16,122,899
Ensembl chrNW_004936485:16,051,974...16,109,978 		JBrowse link
G Ush1c USH1 protein network component harmonin located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936528:1,552,175...1,594,740
Ensembl chrNW_004936528:1,552,289...1,594,801 		JBrowse link
G Whrn whirlin located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936487:3,668,465...3,748,234
Ensembl chrNW_004936487:3,669,104...3,748,238 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16781
    cellular anatomical structure 16693
      organelle 12032
        stereocilium 64
          actin filament bundle of stereocilium 0
          stereocilium base 8
          stereocilium coat 1
          stereocilium membrane 4
          stereocilium shaft 2
          stereocilium tip 21
Path 2
Term Annotations click to browse term
  cellular_component 16781
    cellular anatomical structure 16693
      cell projection 2423
        plasma membrane bounded cell projection 2363
          neuron projection 1482
            stereocilium 64
              actin filament bundle of stereocilium 0
              stereocilium base 8
              stereocilium coat 1
              stereocilium membrane 4
              stereocilium shaft 2
              stereocilium tip 21
paths to the root