ONTOLOGY REPORT - ANNOTATIONS
Term: stereocilium
Accession: GO:0032420
browse the term
Definition: An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
Synonyms: never_in_taxon: NCBITaxon:4751 ! Fungi
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Adcy6
adenylate cyclase 6
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr15:98,484,982...98,508,119
Ensembl chr15:98,487,854...98,507,957
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Adgrv1
adhesion G protein-coupled receptor V1
located_in is_active_in
ISO EXP IBA
(PMID:26754646)
RGD GO_Central MGI
PMID:16301216 PMID:26754646
GO_REF:0000033 GO_REF:0000096 RGD:8548636
NCBI chr13:81,243,187...81,781,504
Ensembl chr13:81,243,187...81,781,273
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Ankrd24
ankyrin repeat domain 24
located_in
IDA
(PMID:35175278)
UniProt
PMID:35175278
NCBI chr10:81,464,352...81,483,446
Ensembl chr10:81,464,374...81,483,444
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Atp8b1
ATPase, class I, type 8B, member 1
located_in
IDA
(PMID:19478059)
UniProt
PMID:19478059
NCBI chr18:64,662,050...64,794,342
Ensembl chr18:64,662,038...64,794,338
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Bbs2
Bardet-Biedl syndrome 2
located_in
IDA
(PMID:25605782)
MGI
PMID:25605782
NCBI chr 8:94,794,580...94,825,997
Ensembl chr 8:94,794,582...94,825,556
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Calb1
calbindin 1
located_in
ISO IEA
RGD GO_Central Ensembl
PMID:16120789
GO_REF:0000096 GO_REF:0000107 RGD:7175527
NCBI chr 4:15,881,264...15,906,709
Ensembl chr 4:15,881,264...15,908,064
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Calb2
calbindin 2
located_in
ISO
RGD GO_Central
PMID:16120789
GO_REF:0000096 RGD:7175527
NCBI chr 8:110,869,158...110,894,844
Ensembl chr 8:110,864,134...110,894,842
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Cdh23
cadherin related 23 (otocadherin)
located_in
IDA
(PMID:12485990), (PMID:15882574), (PMID:16481439), (PMID:17050716)
HGNC-UCL
PMID:12485990 PMID:15882574 PMID:16481439 PMID:17050716
NCBI chr10:60,138,527...60,532,291
Ensembl chr10:60,138,527...60,532,269
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Cib2
calcium and integrin binding family member 2
is_active_in located_in
IBA ISS ISO IDA
(PMID:23023331)
GO_Central UniProt
PMID:23023331
GO_REF:0000024 GO_REF:0000033 GO_REF:0000119
NCBI chr 9:54,452,074...54,467,512
Ensembl chr 9:54,452,078...54,467,502
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Clic5
chloride intracellular channel 5
located_in
IDA
(PMID:17021174)
MGI
PMID:17021174
NCBI chr17:44,445,671...44,591,059
Ensembl chr17:44,445,659...44,591,059
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Clrn1
clarin 1
located_in
IDA
(PMID:19539019)
MGI
PMID:19539019
NCBI chr 3:58,751,449...58,792,633
Ensembl chr 3:58,751,449...58,792,761
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Dock4
dedicator of cytokinesis 4
located_in
IDA
(PMID:16464467)
HGNC-UCL
PMID:16464467
NCBI chr12:40,495,956...40,896,873
Ensembl chr12:40,495,951...40,896,873
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Elmod3
ELMO/CED-12 domain containing 3
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr 6:72,542,905...72,575,396
Ensembl chr 6:72,542,905...72,575,396
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Eps8
epidermal growth factor receptor pathway substrate 8
located_in
IDA
(PMID:21236676), (PMID:24741995)
UniProt
PMID:21236676 PMID:24741995
NCBI chr 6:137,454,242...137,626,262
Ensembl chr 6:137,454,243...137,631,874
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Espn
espin
located_in
IDA ISO
(PMID:20510926)
MGI GO_Central
PMID:20510926
GO_REF:0000119
NCBI chr 4:152,204,788...152,236,871
Ensembl chr 4:152,204,788...152,236,828
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Fscn2
fascin actin-bundling protein 2
located_in
IDA
(PMID:20660251)
UniProt
PMID:20660251
NCBI chr11:120,250,991...120,258,999
Ensembl chr11:120,252,360...120,258,994
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Grxcr1
glutaredoxin, cysteine rich 1
is_active_in located_in
IBA IDA
(PMID:20137774), (PMID:30380417)
GO_Central MGI
PMID:20137774 PMID:30380417
GO_REF:0000033
NCBI chr 5:68,189,122...68,323,741
Ensembl chr 5:68,189,178...68,323,741
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Ift20
intraflagellar transport 20
located_in
IDA
(PMID:25605782)
MGI
PMID:25605782
NCBI chr11:78,427,187...78,432,558
Ensembl chr11:78,427,187...78,432,563
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Kptn
kaptin
located_in
ISS
UniProt
GO_REF:0000024
NCBI chr 7:15,853,801...15,861,441
Ensembl chr 7:15,853,820...15,861,441
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Loxhd1
lipoxygenase homology domains 1
is_active_in located_in
IBA IDA
(PMID:19732867)
GO_Central UniProt
PMID:19732867
GO_REF:0000033
NCBI chr18:77,369,354...77,530,628
Ensembl chr18:77,369,654...77,530,626
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Minar2
membrane integral NOTCH2 associated receptor 2
is_active_in
IMP
(PMID:35727972)
MGI
PMID:35727972
NCBI chr18:59,195,264...59,210,034
Ensembl chr18:59,195,320...59,210,034
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Mpp1
membrane protein, palmitoylated
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr X:74,153,339...74,174,622
Ensembl chr X:74,153,339...74,174,622
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Myo15a
myosin XVA
located_in
IDA
(PMID:20016102)
MGI
PMID:20016102
NCBI chr11:60,360,165...60,419,195
Ensembl chr11:60,360,165...60,419,195
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Myo1c
myosin IC
located_in
IDA
(PMID:17050716)
MGI
PMID:17050716
NCBI chr11:75,541,345...75,565,450
Ensembl chr11:75,541,330...75,564,736
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Myo7a
myosin VIIA
is_active_in located_in
EXP IDA
(PMID:26754646) (PMID:12485990), (PMID:16481439), (PMID:20016102), (PMID:27525485)
MGI
PMID:12485990 PMID:16481439 PMID:20016102 PMID:26754646 PMID:27525485
NCBI chr 7:97,700,261...97,768,730
Ensembl chr 7:97,700,267...97,768,731
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Nherf1
NHERF family PDZ scaffold protein 1
located_in
IDA
(PMID:24920589)
MGI
PMID:24920589
NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
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Nherf2
NHERF family PDZ scaffold protein 2
located_in
IDA
(PMID:24920589)
MGI
PMID:24920589
NCBI chr17:24,858,255...24,869,279
Ensembl chr17:24,858,260...24,869,301
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Ocm
oncomodulin
located_in
ISO IEA
RGD Ensembl GO_Central
PMID:16120789
GO_REF:0000096 GO_REF:0000107 RGD:7175527
NCBI chr 5:143,956,615...143,987,691
Ensembl chr 5:143,956,622...143,963,488
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Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
located_in
IDA
(PMID:23533177)
MGI
PMID:23533177
NCBI chr11:74,564,775...74,615,210
Ensembl chr11:74,564,775...74,615,496
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Pcdh15
protocadherin 15
is_active_in located_in
EXP IDA
(PMID:26754646) (PMID:14570705)
MGI HGNC-UCL
PMID:14570705 PMID:26754646
NCBI chr10:72,932,003...74,485,663
Ensembl chr10:72,935,174...74,485,569
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Pdzd7
PDZ domain containing 7
located_in
IDA
(PMID:27525485), (PMID:31448880)
UniProt
PMID:27525485 PMID:31448880
NCBI chr19:45,015,346...45,048,273
Ensembl chr19:45,015,345...45,034,156
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Piezo1
piezo-type mechanosensitive ion channel component 1
located_in
IDA
(PMID:38228630)
UniProt
PMID:38228630
NCBI chr 8:123,208,437...123,278,068
Ensembl chr 8:123,208,437...123,278,068
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Piezo2
piezo-type mechanosensitive ion channel component 2
located_in
IDA
(PMID:38228630)
UniProt
PMID:38228630
NCBI chr18:63,143,284...63,520,787
Ensembl chr18:63,143,284...63,520,254
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Pls1
plastin 1 (I-isoform)
located_in
IDA
(PMID:25124451)
UniProt
PMID:25124451
NCBI chr 9:95,634,695...95,727,359
Ensembl chr 9:95,634,695...95,727,364
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Pls3
plastin 3 (T-isoform)
located_in
ISO
RGD GO_Central
PMID:12378542
GO_REF:0000096 RGD:731234
NCBI chr X:74,829,259...74,918,788
Ensembl chr X:74,829,260...74,918,788
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Prom1
prominin 1
located_in
IDA
(PMID:15316084)
MGI
PMID:15316084
NCBI chr 5:44,150,963...44,260,850
Ensembl chr 5:44,150,962...44,259,374
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Pvalb
parvalbumin
located_in
ISO
RGD GO_Central
PMID:16120789
GO_REF:0000096 RGD:7175527
NCBI chr15:78,075,312...78,090,600
Ensembl chr15:78,075,314...78,090,600
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Rdx
radixin
located_in
IDA
(PMID:17021174)
MGI
PMID:17021174
NCBI chr 9:51,958,450...52,000,038
Ensembl chr 9:51,958,473...52,011,763
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Rhoc
ras homolog family member C
located_in
IDA
(PMID:27269051)
UniProt
PMID:27269051
NCBI chr 3:104,696,350...104,701,775
Ensembl chr 3:104,695,691...104,701,775
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Ripor2
RHO family interacting cell polarization regulator 2
located_in
ISS ISO IDA
(PMID:27269051)
UniProt GO_Central
PMID:27269051
GO_REF:0000024 GO_REF:0000096
NCBI chr13:24,685,513...24,917,789
Ensembl chr13:24,685,508...24,917,799
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Slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
located_in
ISO IEA
RGD GO_Central UniProt
PMID:16301216
GO_REF:0000044 GO_REF:0000096 RGD:8548636
NCBI chr14:7,669,819...7,766,808
Ensembl chr14:7,669,823...7,767,484
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Stx4a
syntaxin 4A (placental)
located_in
IDA
(PMID:36355422)
UniProt
PMID:36355422
NCBI chr 7:127,439,832...127,450,160
Ensembl chr 7:127,423,466...127,448,191
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Tmc1
transmembrane channel-like gene family 1
located_in
IDA
(PMID:38228630)
UniProt
PMID:38228630
NCBI chr19:20,760,820...20,931,566
Ensembl chr19:20,760,822...20,931,566
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Tmc2
transmembrane channel-like gene family 2
located_in
IDA
(PMID:38228630)
UniProt
PMID:38228630
NCBI chr 2:130,037,114...130,106,365
Ensembl chr 2:130,037,114...130,106,365
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Tprn
taperin
located_in
IDA
(PMID:20170899), (PMID:27269051)
UniProt
PMID:20170899 PMID:27269051
NCBI chr 2:25,152,610...25,159,898
Ensembl chr 2:25,152,630...25,159,897
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Tspear
thrombospondin type laminin G domain and EAR repeats
located_in
IDA
(PMID:22678063)
UniProt
PMID:22678063
NCBI chr10:77,521,942...77,722,844
Ensembl chr10:77,522,403...77,722,855
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Twf2
twinfilin actin binding protein 2
located_in
IDA
(PMID:19955359)
BHF-UCL
PMID:19955359
NCBI chr 9:106,080,307...106,092,586
Ensembl chr 9:106,080,307...106,092,588
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Ush1c
USH1 protein network component harmonin
located_in is_active_in
ISO IDA EXP
(PMID:12485990), (PMID:20016102) (PMID:26754646)
RGD GO_Central MGI
PMID:12485990 PMID:16301216 PMID:20016102 PMID:26754646
GO_REF:0000096 RGD:8548636
NCBI chr 7:45,844,774...45,887,984
Ensembl chr 7:45,844,774...45,887,927
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Ush2a
usherin
located_in
ISO
hair cell
RGD GO_Central
PMID:16301216
GO_REF:0000096 RGD:8548636
NCBI chr 1:187,995,035...188,697,694
Ensembl chr 1:187,994,220...188,697,238
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Whrn
whirlin
located_in
ISO IDA
(PMID:15590698), (PMID:15590699), (PMID:15654330)
RGD UniProt GO_Central
PMID:15590698 PMID:15590699 PMID:15654330 PMID:16434480
GO_REF:0000096 RGD:1600128
NCBI chr 4:63,333,145...63,414,320
Ensembl chr 4:63,333,147...63,414,228
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Zswim6
zinc finger SWIM-type containing 6
located_in
IDA
(PMID:25105228)
MGI
PMID:25105228
NCBI chr13:107,861,152...108,026,598
Ensembl chr13:107,861,152...108,026,598
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Clic5
chloride intracellular channel 5
located_in
IDA ISO
(PMID:37952086)
UniProt GO_Central
PMID:37952086
GO_REF:0000096
NCBI chr17:44,445,671...44,591,059
Ensembl chr17:44,445,659...44,591,059
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Grxcr2
glutaredoxin, cysteine rich 2
is_active_in located_in
IBA IDA
(PMID:30380417)
GO_Central MGI
PMID:30380417
GO_REF:0000033
NCBI chr18:42,118,388...42,132,114
Ensembl chr18:42,118,388...42,132,114
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Myo7a
myosin VIIA
located_in
IDA
(PMID:17567809)
UniProt
PMID:17567809
NCBI chr 7:97,700,261...97,768,730
Ensembl chr 7:97,700,267...97,768,731
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Pjvk
pejvakin
located_in
IDA
(PMID:28209736)
MGI
PMID:28209736
NCBI chr 2:76,480,617...76,488,898
Ensembl chr 2:76,478,820...76,488,900
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Ptprq
protein tyrosine phosphatase receptor type Q
located_in
IDA
(PMID:24285636), (PMID:37952086)
UniProt
PMID:24285636 PMID:37952086
NCBI chr10:107,350,224...107,555,939
Ensembl chr10:107,352,910...107,555,912
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Rdx
radixin
located_in
IDA
(PMID:24285636), (PMID:30159668)
UniProt
PMID:24285636 PMID:30159668
NCBI chr 9:51,958,450...52,000,038
Ensembl chr 9:51,958,473...52,011,763
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Tprn
taperin
is_active_in located_in
IBA IDA
(PMID:24285636), (PMID:28209736), (PMID:30159668), (PMID:30380417), (PMID:37952086)
GO_Central UniProt
PMID:24285636 PMID:28209736 PMID:30159668 PMID:30380417 PMID:37952086
GO_REF:0000033
NCBI chr 2:25,152,610...25,159,898
Ensembl chr 2:25,152,630...25,159,897
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Triobp
TRIO and F-actin binding protein
located_in
IDA
(PMID:28209736)
MGI
PMID:28209736
NCBI chr15:78,831,924...78,890,069
Ensembl chr15:78,831,924...78,890,069
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Pkhd1l1
polycystic kidney and hepatic disease 1-like 1
located_in
IDA
(PMID:31444330)
MGI
PMID:31444330
NCBI chr15:44,320,792...44,464,772
Ensembl chr15:44,320,890...44,464,765
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Adgrv1
adhesion G protein-coupled receptor V1
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr13:81,243,187...81,781,504
Ensembl chr13:81,243,187...81,781,273
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Cacna1b
calcium channel, voltage-dependent, N type, alpha 1B subunit
ISO
RGD
PMID:10408625
RGD:11556226 (All species) (All species)
NCBI chr 2:24,493,872...24,653,210
Ensembl chr 2:24,493,899...24,653,164
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Clrn2
clarin 2
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr 5:45,611,021...45,621,824
Ensembl chr 5:45,611,093...45,621,491
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Mcoln3
mucolipin 3
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr 3:145,799,032...145,847,563
Ensembl chr 3:145,823,205...145,847,561
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Myo1c
myosin IC
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr11:75,541,345...75,565,450
Ensembl chr11:75,541,330...75,564,736
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Pkhd1l1
polycystic kidney and hepatic disease 1-like 1
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr15:44,320,792...44,464,772
Ensembl chr15:44,320,890...44,464,765
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Ripor2
RHO family interacting cell polarization regulator 2
located_in
ISO
MGI
GO_REF:0000008
NCBI chr13:24,685,513...24,917,789
Ensembl chr13:24,685,508...24,917,799
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Ush2a
usherin
located_in
IDA
(PMID:16301217)
BHF-UCL
PMID:16301217
NCBI chr 1:187,995,035...188,697,694
Ensembl chr 1:187,994,220...188,697,238
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Vezt
vezatin, adherens junctions transmembrane protein
located_in
IEA
UniProt
GO_REF:0000044
NCBI chr10:93,797,384...93,871,661
Ensembl chr10:93,775,027...93,871,679
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Fchsd2
FCH and double SH3 domains 2
located_in
IDA
(PMID:23437151)
UniProt
PMID:23437151
NCBI chr 7:100,757,836...100,933,613
Ensembl chr 7:100,742,070...100,933,612
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Grxcr2
glutaredoxin, cysteine rich 2
is_active_in located_in
IBA IDA
(PMID:30380417)
GO_Central MGI
PMID:30380417
GO_REF:0000033
NCBI chr18:42,118,388...42,132,114
Ensembl chr18:42,118,388...42,132,114
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Cdc14a
CDC14 cell division cycle 14A
located_in
IDA
(PMID:29293958)
UniProt
PMID:29293958
NCBI chr 3:116,066,202...116,222,390
Ensembl chr 3:116,066,202...116,222,394
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Cdh23
cadherin related 23 (otocadherin)
located_in
IDA
(PMID:12485990), (PMID:17050716), (PMID:24920589)
MGI
PMID:12485990 PMID:17050716 PMID:24920589
NCBI chr10:60,138,527...60,532,291
Ensembl chr10:60,138,527...60,532,269
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Ceacam16
CEA cell adhesion molecule 16
located_in
IDA
(PMID:21368133)
MGI
PMID:21368133
NCBI chr 7:19,586,022...19,595,224
Ensembl chr 7:19,586,022...19,595,224
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Coro1a
coronin, actin binding protein 1A
is_active_in
EXP
(PMID:26754646)
MGI
PMID:26754646
NCBI chr 7:126,298,946...126,303,925
Ensembl chr 7:126,298,945...126,306,959
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Eps8
epidermal growth factor receptor pathway substrate 8
located_in
IDA
(PMID:23918390)
UniProt
PMID:23918390
NCBI chr 6:137,454,242...137,626,262
Ensembl chr 6:137,454,243...137,631,874
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Eps8l2
EPS8-like 2
located_in
IDA
(PMID:23918390)
UniProt
PMID:23918390
NCBI chr 7:140,918,824...140,942,933
Ensembl chr 7:140,918,793...140,942,933
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Espn
espin
is_active_in located_in
EXP IDA
(PMID:26754646) (PMID:22264607), (PMID:26754646)
MGI
PMID:22264607 PMID:26754646
NCBI chr 4:152,204,788...152,236,871
Ensembl chr 4:152,204,788...152,236,828
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Espnl
espin-like
is_active_in located_in
EXP IDA
(PMID:26754646) (PMID:26926603)
MGI UniProt
PMID:26754646 PMID:26926603
NCBI chr 1:91,249,845...91,277,130
Ensembl chr 1:91,249,797...91,276,028
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Homer2
homer scaffolding protein 2
located_in
IDA
(PMID:25816005)
UniProt
PMID:25816005
NCBI chr 7:81,250,229...81,356,673
Ensembl chr 7:81,250,229...81,357,275
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Lhfpl5
lipoma HMGIC fusion partner-like 5
located_in
IDA
(PMID:23217710)
MGI
PMID:23217710
NCBI chr17:28,794,330...28,802,567
Ensembl chr17:28,794,615...28,804,653
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Morn4
MORN repeat containing 4
is_active_in located_in
EXP IDA
(PMID:26754646)
MGI UniProt
PMID:26754646
NCBI chr19:42,063,378...42,074,815
Ensembl chr19:42,063,378...42,074,796
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Myo3a
myosin IIIA
is_active_in located_in
EXP IBA IDA
(PMID:26754646) (PMID:21165622), (PMID:22264607), (PMID:26754646)
MGI GO_Central UniProt
PMID:21165622 PMID:22264607 PMID:26754646
GO_REF:0000033
NCBI chr 2:22,232,360...22,508,693
Ensembl chr 2:22,232,316...22,508,264
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Myo3b
myosin IIIB
is_active_in located_in
EXP IBA IDA
(PMID:26754646) (PMID:22264607), (PMID:26754646)
MGI GO_Central UniProt
PMID:22264607 PMID:26754646
GO_REF:0000033
NCBI chr 2:69,869,464...70,259,542
Ensembl chr 2:69,869,470...70,259,542
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Nherf1
NHERF family PDZ scaffold protein 1
located_in
IDA
(PMID:24920589)
MGI
PMID:24920589
NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
G
Pdzd7
PDZ domain containing 7
is_active_in
IBA
GO_Central
GO_REF:0000033
NCBI chr19:45,015,346...45,048,273
Ensembl chr19:45,015,345...45,034,156
G
Pkhd1l1
polycystic kidney and hepatic disease 1-like 1
located_in
IDA
(PMID:31444330)
MGI
PMID:31444330
NCBI chr15:44,320,792...44,464,772
Ensembl chr15:44,320,890...44,464,765
G
Strc
stereocilin
is_active_in located_in
IBA IDA
(PMID:18849963), (PMID:21165971), (PMID:24920589), (PMID:31448880)
GO_Central MGI
PMID:18849963 PMID:21165971 PMID:24920589 PMID:31448880
GO_REF:0000033
NCBI chr 2:121,193,729...121,211,851
Ensembl chr 2:121,194,209...121,217,649
G
Tmc1
transmembrane channel-like gene family 1
located_in
IDA
(PMID:22105175)
MGI
PMID:22105175
NCBI chr19:20,760,820...20,931,566
Ensembl chr19:20,760,822...20,931,566
G
Tmc2
transmembrane channel-like gene family 2
located_in
IDA
(PMID:22105175)
MGI
PMID:22105175
NCBI chr 2:130,037,114...130,106,365
Ensembl chr 2:130,037,114...130,106,365
G
Ush1c
USH1 protein network component harmonin
is_active_in
IBA
GO_Central
GO_REF:0000033
NCBI chr 7:45,844,774...45,887,984
Ensembl chr 7:45,844,774...45,887,927
G
Whrn
whirlin
located_in is_active_in
IDA IBA ISO
(PMID:24334608), (PMID:31448880)
MGI GO_Central
PMID:24334608 PMID:31448880
GO_REF:0000033 GO_REF:0000096
NCBI chr 4:63,333,145...63,414,320
Ensembl chr 4:63,333,147...63,414,228
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