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ONTOLOGY REPORT - ANNOTATIONS

Term:stereocilium
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Accession:GO:0032420 term browser browse the term
Definition:An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
Synonyms:never_in_taxon: NCBITaxon:4751 ! Fungi

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stereocilium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRV1 adhesion G protein-coupled receptor V1 located_in
is_active_in		 ISO
IEA		 (PMID:26754646) RGD
UniProt
TreeGrafter
MGI		 PMID:16301216 PMID:26754646 GO_REF:0000044 GO_REF:0000118 RGD:8548636 NCBI chr 4:84,498,630...85,082,813
Ensembl chr 4:84,498,573...85,083,504 		JBrowse link
G ANKRD24 ankyrin repeat domain 24 located_in ISO (PMID:35175278) UniProt PMID:35175278 NCBI chr 6:3,932,677...3,972,476
Ensembl chr 6:3,949,211...3,972,176 		JBrowse link
G ATP8B1 ATPase phospholipid transporting 8B1 located_in IEA Ensembl GO_REF:0000107 NCBI chr18:21,930,150...22,086,371
Ensembl chr18:21,930,837...22,088,480 		JBrowse link
G BBS2 Bardet-Biedl syndrome 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:42,395,387...42,430,204
Ensembl chr 5:42,395,230...42,430,154 		JBrowse link
G CALB1 calbindin 1 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 8:85,135,956...85,160,806
Ensembl chr 8:85,137,528...85,160,855 		JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 5:54,503,635...54,538,304
Ensembl chr 5:54,504,082...54,538,441 		JBrowse link
G CIB2 calcium and integrin binding family member 2 located_in IEA TreeGrafter
Ensembl
UniProt		 GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr26:5,222,657...5,248,133
Ensembl chr26:5,222,902...5,248,191 		JBrowse link
G CLIC5 chloride intracellular channel 5 located_in ISO (PMID:17021174) MGI PMID:17021174 NCBI chr17:26,231,192...26,364,076
Ensembl chr17:26,231,728...26,343,346 		JBrowse link
G CLRN1 clarin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,713,439...39,761,647
Ensembl chr15:39,717,716...39,761,306 		JBrowse link
G DOCK4 dedicator of cytokinesis 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr21:80,548,079...81,022,410
Ensembl chr21:80,547,655...80,812,702 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor located_in IEA Ensembl GO_REF:0000107 NCBI chr11:15,522,761...15,691,343
Ensembl chr11:15,522,616...15,691,133 		JBrowse link
G ESPN espin located_in IEA UniProt
Ensembl		 GO_REF:0000044 GO_REF:0000107 NCBI chr20:125,282,283...125,320,436
Ensembl chr20:125,278,313...125,320,365 		JBrowse link
G ESPNL espin like located_in IEA UniProt GO_REF:0000044 NCBI chr10:124,122,495...124,152,355
Ensembl chr10:124,123,379...124,152,127 		JBrowse link
G FSCN2 fascin actin-bundling protein 2, retinal located_in IEA Ensembl GO_REF:0000107 NCBI chr16:73,472,582...73,482,440
Ensembl chr16:73,474,519...73,481,967 		JBrowse link
G GRXCR1 glutaredoxin and cysteine rich domain containing 1 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr27:7,300,259...7,436,241
Ensembl chr27:7,300,376...7,435,093 		JBrowse link
G IFT20 intraflagellar transport 20 located_in ISO (PMID:25605782) MGI PMID:25605782 NCBI chr16:22,094,383...22,102,234 JBrowse link
G IFT20 intraflagellar transport 20 located_in IEA Ensembl GO_REF:0000107 Ensembl chr16:22,094,003...22,098,452 JBrowse link
G LOC103216037 cadherin-23 located_in ISO (PMID:12485990), (PMID:15882574), (PMID:16481439), (PMID:17050716) HGNC-UCL PMID:12485990 PMID:15882574 PMID:16481439 PMID:17050716 NCBI chr 9:59,475,126...59,893,824 JBrowse link
G LOC103219967 thrombospondin-type laminin G domain and EAR repeat-containing protein located_in IEA Ensembl
UniProt		 GO_REF:0000044 GO_REF:0000107 NCBI chr 2:88,219,663...88,425,531
Ensembl chr 2:88,221,529...88,287,701 		JBrowse link
G LOC103227720 twinfilin-2 located_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752 		JBrowse link
G LOXHD1 lipoxygenase homology PLAT domains 1 located_in ISO (PMID:19732867) UniProt PMID:19732867 NCBI chr18:34,247,584...34,431,038
Ensembl chr18:34,249,250...34,430,532 		JBrowse link
G MINAR2 membrane integral NOTCH2 associated receptor 2 is_active_in
located_in		 ISO
IEA		 (PMID:35727972) MGI
Ensembl		 PMID:35727972 GO_REF:0000107 NCBI chr23:32,655,661...32,672,945
Ensembl chr23:32,655,735...32,674,117 		JBrowse link
G MORN4 MORN repeat containing 4 located_in IEA UniProt GO_REF:0000044 NCBI chr 9:90,775,224...90,794,745
Ensembl chr 9:90,776,920...90,780,252 		JBrowse link
G MPP1 MAGUK p55 scaffold protein 1 located_in IEA UniProt GO_REF:0000044 NCBI chr  X:129,030,736...129,057,952
Ensembl chr  X:129,030,735...129,044,777 		JBrowse link
G MYO15A myosin XVA located_in IEA Ensembl GO_REF:0000107 NCBI chr16:17,157,275...17,217,609
Ensembl chr16:17,157,490...17,218,009 		JBrowse link
G MYO1C myosin IC located_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,137,469...1,167,497 JBrowse link
G MYO7A myosin VIIA is_active_in
located_in		 ISO
IEA		 (PMID:26754646) MGI
Ensembl		 PMID:26754646 GO_REF:0000107 NCBI chr 1:68,334,781...68,423,215
Ensembl chr 1:68,350,598...68,425,625 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,889,454...46,910,776
Ensembl chr16:46,888,942...46,910,842 		JBrowse link
G NHERF2 NHERF family PDZ scaffold protein 2 located_in ISO (PMID:24920589) MGI PMID:24920589 NCBI chr 5:1,923,773...1,935,641
Ensembl chr 5:1,924,131...1,939,062 		JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,270,126...2,293,705
Ensembl chr16:2,270,085...2,296,825 		JBrowse link
G PCDH15 protocadherin related 15 located_in
is_active_in		 IEA
ISO		 (PMID:26754646) InterPro
MGI		 PMID:26754646 GO_REF:0000002 NCBI chr 9:75,642,985...77,415,370
Ensembl chr 9:76,726,627...77,398,716 		JBrowse link
G PDZD7 PDZ domain containing 7 located_in ISO (PMID:27525485), (PMID:31448880) UniProt PMID:27525485 PMID:31448880 NCBI chr 9:94,026,036...94,049,043 JBrowse link
G PIEZO1 piezo type mechanosensitive ion channel component 1 (Er blood group) located_in ISO (PMID:38228630) UniProt PMID:38228630 NCBI chr 5:74,100,675...74,167,194
Ensembl chr 5:74,100,929...74,134,167 		JBrowse link
G PIEZO2 piezo type mechanosensitive ion channel component 2 located_in ISO (PMID:38228630) UniProt PMID:38228630 NCBI chr18:70,161,961...70,623,912
Ensembl chr18:70,246,132...70,622,611 		JBrowse link
G PLS1 plastin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:47,919,807...48,031,158
Ensembl chr15:47,919,823...48,003,805 		JBrowse link
G PLS3 plastin 3 ISO RGD PMID:12378542 RGD:731234
G PROM1 prominin 1 located_in ISO (PMID:15316084) MGI PMID:15316084 NCBI chr27:34,093,699...34,243,630
Ensembl chr27:34,129,532...34,243,778 		JBrowse link
G PVALB parvalbumin ISO RGD PMID:16120789 RGD:7175527 NCBI chr19:19,501,100...19,520,031
Ensembl chr19:19,501,293...19,517,340 		JBrowse link
G RDX radixin located_in ISO (PMID:17021174) MGI PMID:17021174 NCBI chr 1:101,554,640...101,647,765
Ensembl chr 1:101,554,334...101,623,093 		JBrowse link
G RHOC ras homolog family member C located_in IEA Ensembl GO_REF:0000107 NCBI chr20:20,932,533...20,938,703
Ensembl chr20:20,936,018...20,938,284 		JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:47,197,067...47,441,413
Ensembl chr17:47,308,984...47,451,779 		JBrowse link
G SLC4A7 solute carrier family 4 member 7 ISO RGD PMID:16301216 RGD:8548636 NCBI chr15:71,942,498...72,047,781
Ensembl chr15:71,961,350...72,047,617 		JBrowse link
G STX4 syntaxin 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:27,725,121...27,734,442
Ensembl chr 5:27,724,495...27,732,736 		JBrowse link
G TMC1 transmembrane channel like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:83,672,786...83,883,985
Ensembl chr12:83,735,988...83,877,251 		JBrowse link
G TMC2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:53,903,305...54,002,599
Ensembl chr 2:53,903,842...53,979,535 		JBrowse link
G TPRN taperin located_in ISO (PMID:20170899), (PMID:27269051) UniProt PMID:20170899 PMID:27269051 NCBI chr12:988,225...997,914 JBrowse link
G USH1C USH1 protein network component harmonin is_active_in
located_in		 ISO (PMID:26754646)
(PMID:12485990), (PMID:20016102)		 RGD
MGI		 PMID:12485990 PMID:16301216 PMID:20016102 PMID:26754646 RGD:8548636 NCBI chr 1:47,428,181...47,477,578
Ensembl chr 1:47,437,596...47,477,834 		JBrowse link
G USH2A usherin ISO hair cell RGD PMID:16301216 RGD:8548636 NCBI chr25:13,171,499...13,950,553
Ensembl chr25:13,173,576...13,947,724 		JBrowse link
G WHRN whirlin located_in ISO
IEA		 RGD
Ensembl		 PMID:16434480 GO_REF:0000107 RGD:1600128 NCBI chr12:25,087,286...25,189,982
Ensembl chr12:25,087,295...25,189,985 		JBrowse link
G ZSWIM6 zinc finger SWIM-type containing 6 located_in ISO (PMID:25105228) MGI PMID:25105228 NCBI chr 4:57,501,906...57,717,375 JBrowse link
stereocilium base term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLIC5 chloride intracellular channel 5 located_in ISO PMID:24285636
(PMID:37952086)		 UniProt PMID:24285636 PMID:37952086 RGD:401966878 NCBI chr17:26,231,192...26,364,076
Ensembl chr17:26,231,728...26,343,346 		JBrowse link
G GRXCR2 glutaredoxin and cysteine rich domain containing 2 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:48,443,668...48,457,079
Ensembl chr23:48,443,748...48,456,614 		JBrowse link
G MYO7A myosin VIIA located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:68,334,781...68,423,215
Ensembl chr 1:68,350,598...68,425,625 		JBrowse link
G PJVK pejvakin located_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,004,113...64,013,025
Ensembl chr10:64,005,259...64,014,571 		JBrowse link
G PTPRQ protein tyrosine phosphatase receptor type Q located_in IEA Ensembl GO_REF:0000107 NCBI chr11:75,943,793...76,154,604
Ensembl chr11:75,943,260...76,154,083 		JBrowse link
G RDX radixin located_in ISO (PMID:24285636), (PMID:30159668) UniProt PMID:24285636 PMID:30159668 NCBI chr 1:101,554,640...101,647,765
Ensembl chr 1:101,554,334...101,623,093 		JBrowse link
G TPRN taperin located_in ISO (PMID:24285636), (PMID:28209736), (PMID:30159668), (PMID:30380417), (PMID:37952086) UniProt PMID:24285636 PMID:28209736 PMID:30159668 PMID:30380417 PMID:37952086 NCBI chr12:988,225...997,914 JBrowse link
G TPRN taperin located_in IEA TreeGrafter GO_REF:0000118 Ensembl chr12:989,400...997,918 JBrowse link
G TRIOBP TRIO and F-actin binding protein located_in ISO (PMID:28209736) MGI PMID:28209736 NCBI chr19:20,447,340...20,476,669 JBrowse link
G TRIOBP TRIO and F-actin binding protein located_in IEA Ensembl GO_REF:0000107 Ensembl chr19:20,404,089...20,470,706 JBrowse link
stereocilium coat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKHD1L1 PKHD1 like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:104,072,701...104,230,809
Ensembl chr 8:104,073,327...104,230,960 		JBrowse link
stereocilium membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1B calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:10408625 RGD:11556226 (All species) (All species) NCBI chr12:75,441...335,980
Ensembl chr12:78,011...335,820 		JBrowse link
G MYO1C myosin IC located_in IEA UniProt GO_REF:0000044 NCBI chr16:1,137,469...1,167,497 JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 located_in IEA UniProt GO_REF:0000044 NCBI chr17:47,197,067...47,441,413
Ensembl chr17:47,308,984...47,451,779 		JBrowse link
G USH2A usherin located_in IEA Ensembl GO_REF:0000107 NCBI chr25:13,171,499...13,950,553
Ensembl chr25:13,173,576...13,947,724 		JBrowse link
stereocilium shaft term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCHSD2 FCH and double SH3 domains 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:64,073,563...64,383,695
Ensembl chr 1:64,075,109...64,383,589 		JBrowse link
G GRXCR2 glutaredoxin and cysteine rich domain containing 2 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:48,443,668...48,457,079
Ensembl chr23:48,443,748...48,456,614 		JBrowse link
stereocilium tip term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC14A cell division cycle 14A located_in IEA Ensembl GO_REF:0000107 NCBI chr20:32,822,748...32,987,739
Ensembl chr20:32,822,746...32,986,718 		JBrowse link
G CEACAM16 CEA cell adhesion molecule 16, tectorial membrane component located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,179,822...38,189,731
Ensembl chr 6:38,180,658...38,187,342 		JBrowse link
G CORO1A coronin 1A is_active_in ISO (PMID:26754646) MGI PMID:26754646 NCBI chr 5:26,482,269...26,488,537
Ensembl chr 5:26,480,753...26,487,929 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor located_in IEA Ensembl GO_REF:0000107 NCBI chr11:15,522,761...15,691,343
Ensembl chr11:15,522,616...15,691,133 		JBrowse link
G EPS8L2 EPS8 signaling adaptor L2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:523,811...540,781
Ensembl chr 1:523,524...540,803 		JBrowse link
G ESPN espin is_active_in
located_in		 ISO (PMID:26754646)
(PMID:22264607), (PMID:26754646)		 MGI PMID:22264607 PMID:26754646 NCBI chr20:125,282,283...125,320,436
Ensembl chr20:125,278,313...125,320,365 		JBrowse link
G ESPNL espin like is_active_in
located_in		 ISO
IEA		 (PMID:26754646) MGI
Ensembl		 PMID:26754646 GO_REF:0000107 NCBI chr10:124,122,495...124,152,355
Ensembl chr10:124,123,379...124,152,127 		JBrowse link
G HOMER2 homer scaffold protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr29:2,667,718...2,810,238
Ensembl chr29:2,706,134...2,803,372 		JBrowse link
G LHFPL5 LHFPL tetraspan subfamily member 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:36,295,612...36,313,964
Ensembl chr17:36,298,479...36,313,490 		JBrowse link
G LOC103216037 cadherin-23 located_in ISO (PMID:12485990), (PMID:17050716), (PMID:24920589) MGI PMID:12485990 PMID:17050716 PMID:24920589 NCBI chr 9:59,475,126...59,893,824 JBrowse link
G LOC103245735 stereocilin located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr26:39,376,441...39,397,613
Ensembl chr26:39,378,318...39,401,072 		JBrowse link
G MORN4 MORN repeat containing 4 located_in
is_active_in		 IEA
ISO		 (PMID:26754646) Ensembl
MGI		 PMID:26754646 GO_REF:0000107 NCBI chr 9:90,775,224...90,794,745
Ensembl chr 9:90,776,920...90,780,252 		JBrowse link
G MYO3A myosin IIIA is_active_in
located_in		 ISO (PMID:26754646)
(PMID:21165622), (PMID:22264607), (PMID:26754646)		 MGI
UniProt		 PMID:21165622 PMID:22264607 PMID:26754646 NCBI chr 9:25,635,918...25,902,552 JBrowse link
G MYO3B myosin IIIB is_active_in
located_in		 ISO (PMID:26754646)
(PMID:22264607), (PMID:26754646)		 MGI
UniProt		 PMID:22264607 PMID:26754646 NCBI chr10:55,710,658...56,184,514 JBrowse link
G MYO3B myosin IIIB located_in IEA TreeGrafter GO_REF:0000118 Ensembl chr10:55,907,731...56,074,968 JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,889,454...46,910,776
Ensembl chr16:46,888,942...46,910,842 		JBrowse link
G PDZD7 PDZ domain containing 7 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:94,026,036...94,049,043 JBrowse link
G PKHD1L1 PKHD1 like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:104,072,701...104,230,809
Ensembl chr 8:104,073,327...104,230,960 		JBrowse link
G TMC1 transmembrane channel like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:83,672,786...83,883,985
Ensembl chr12:83,735,988...83,877,251 		JBrowse link
G TMC2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:53,903,305...54,002,599
Ensembl chr 2:53,903,842...53,979,535 		JBrowse link
G USH1C USH1 protein network component harmonin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:47,428,181...47,477,578
Ensembl chr 1:47,437,596...47,477,834 		JBrowse link
G WHRN whirlin located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:25,087,286...25,189,982
Ensembl chr12:25,087,295...25,189,985 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17898
    cellular anatomical structure 17793
      organelle 13138
        stereocilium 69
          actin filament bundle of stereocilium 0
          stereocilium base 10
          stereocilium coat 1
          stereocilium membrane 4
          stereocilium shaft 2
          stereocilium tip 22
Path 2
Term Annotations click to browse term
  cellular_component 17898
    cellular anatomical structure 17793
      cell projection 2491
        plasma membrane bounded cell projection 2425
          neuron projection 1503
            stereocilium 69
              actin filament bundle of stereocilium 0
              stereocilium base 10
              stereocilium coat 1
              stereocilium membrane 4
              stereocilium shaft 2
              stereocilium tip 22
paths to the root