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ONTOLOGY REPORT - ANNOTATIONS


Term:stereocilium
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Accession:GO:0032420 term browser browse the term
Definition:An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
Synonyms:never_in_taxon: NCBITaxon:4751 ! Fungi



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stereocilium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRV1 adhesion G protein-coupled receptor V1 located_in
is_active_in
ISO
IEA
(PMID:26754646) RGD
UniProt
TreeGrafter
MGI
PMID:16301216 PMID:26754646 GO_REF:0000044 GO_REF:0000118 RGD:8548636 NCBI chr 5:24,208,844...24,811,284
Ensembl chr 5:24,341,808...24,945,477
JBrowse link
G ANKRD24 ankyrin repeat domain 24 located_in ISO (PMID:35175278) UniProt PMID:35175278 NCBI chr19:3,206,152...3,246,886 JBrowse link
G ATP8B1 ATPase phospholipid transporting 8B1 located_in ISO (PMID:19478059) UniProt PMID:19478059 NCBI chr18:51,035,483...51,187,461
Ensembl chr18:54,370,447...54,522,196
JBrowse link
G BBS2 Bardet-Biedl syndrome 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:36,756,699...36,807,652
Ensembl chr16:55,902,945...55,940,053
JBrowse link
G CALB1 calbindin 1 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 8:86,747,702...86,771,995
Ensembl chr 8:88,699,532...88,723,814
JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:16120789 RGD:7175527 NCBI chr16:53,620,317...53,653,372
Ensembl chr16:71,195,770...71,227,937
JBrowse link
G CIB2 calcium and integrin binding family member 2 located_in IEA Ensembl
UniProt
TreeGrafter
GO_REF:0000044 GO_REF:0000107 GO_REF:0000118 NCBI chr15:57,033,782...57,060,650
Ensembl chr15:75,998,797...76,025,485
JBrowse link
G CLIC5 chloride intracellular channel 5 located_in ISO (PMID:17021174) MGI PMID:17021174 NCBI chr 6:45,474,797...45,592,407
Ensembl chr 6:46,753,013...46,934,100
JBrowse link
G CLRN1 clarin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:147,954,124...148,000,895
Ensembl chr 3:155,526,011...155,573,684
JBrowse link
G DOCK4 dedicator of cytokinesis 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:103,697,418...104,169,469
Ensembl chr 7:116,400,535...116,871,755
JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor located_in IEA Ensembl GO_REF:0000107 NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117
JBrowse link
G ESPN espin located_in ISO (PMID:29572253)
(PMID:20510926)
UniProt
MGI
PMID:20510926 PMID:29572253 NCBI chr 1:5,184,666...5,222,473 JBrowse link
G ESPNL espin like located_in IEA UniProt GO_REF:0000044 NCBI chr2B:125,331,809...125,364,719
Ensembl chr2B:244,182,781...244,214,009
JBrowse link
G FSCN2 fascin actin-bundling protein 2, retinal located_in IEA Ensembl GO_REF:0000107 NCBI chr17:75,974,971...75,993,275
Ensembl chr17:81,687,051...81,694,823
JBrowse link
G GRXCR1 glutaredoxin and cysteine rich domain containing 1 located_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 4:37,214,515...37,352,195
Ensembl chr 4:43,063,313...43,200,436
JBrowse link
G IFT20 intraflagellar transport 20 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,438,960...28,446,113
Ensembl chr17:28,941,303...28,948,129
JBrowse link
G LOC100971960 unconventional myosin-XV located_in ISO (PMID:20016102) MGI PMID:20016102 NCBI chr17:32,661,499...32,723,320 JBrowse link
G LOC100983880 cadherin-23 located_in IEA Ensembl GO_REF:0000107 NCBI chr10:67,866,979...68,286,008
Ensembl chr10:70,434,801...70,810,240
JBrowse link
G LOC100986336 twinfilin-2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,163,388...52,181,473
Ensembl chr 3:53,400,191...53,410,743
Ensembl chr 3:53,400,191...53,410,743
JBrowse link
G LOXHD1 lipoxygenase homology PLAT domains 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:39,756,531...39,936,317
Ensembl chr18:43,290,579...43,469,921
JBrowse link
G MINAR2 membrane integral NOTCH2 associated receptor 2 is_active_in ISO (PMID:35727972) MGI PMID:35727972 NCBI chr 5:125,163,230...125,182,801
Ensembl chr 5:131,335,020...131,353,934
JBrowse link
G MORN4 MORN repeat containing 4 located_in IEA UniProt GO_REF:0000044 NCBI chr10:94,235,061...94,254,509 JBrowse link
G MPP1 MAGUK p55 scaffold protein 1 located_in IEA UniProt GO_REF:0000044 NCBI chr  X:144,258,416...144,285,658
Ensembl chr  X:154,099,463...154,126,575
JBrowse link
G MYO1C myosin IC located_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,446,506...1,475,634
Ensembl chr17:1,345,143...1,375,540
JBrowse link
G MYO7A myosin VIIA located_in
is_active_in
IEA
ISO
(PMID:26754646) Ensembl
MGI
PMID:26754646 GO_REF:0000107 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752
JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:68,694,468...68,715,157
Ensembl chr17:74,250,406...74,271,234
JBrowse link
G NHERF2 NHERF family PDZ scaffold protein 2 located_in ISO (PMID:24920589) MGI PMID:24920589 NCBI chr16:664,310...676,640
Ensembl chr16:2,115,583...2,127,069
JBrowse link
G OCM oncomodulin ISO RGD PMID:16120789 RGD:7175527 NCBI chr 7:6,066,257...6,126,400 JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:2,584,349...2,676,928
Ensembl chr17:2,590,007...2,680,994
JBrowse link
G PCDH15 protocadherin related 15 located_in
is_active_in
IEA
ISO
(PMID:26754646) InterPro
MGI
PMID:26754646 GO_REF:0000002 NCBI chr10:50,452,290...52,236,538
Ensembl chr10:52,666,969...53,536,611
JBrowse link
G PDZD7 PDZ domain containing 7 located_in IEA Ensembl GO_REF:0000107 NCBI chr10:97,608,969...97,632,508
Ensembl chr10:101,085,370...101,107,034
JBrowse link
G PIEZO1 piezo type mechanosensitive ion channel component 1 (Er blood group) located_in ISO (PMID:38228630) UniProt PMID:38228630 NCBI chr16:69,428,461...69,498,454
Ensembl chr16:89,088,323...89,125,068
JBrowse link
G PIEZO2 piezo type mechanosensitive ion channel component 2 located_in ISO (PMID:38228630) UniProt PMID:38228630 NCBI chr18:3,141,285...3,619,885
Ensembl chr18:5,407,467...5,882,928
JBrowse link
G PLS1 plastin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:139,629,825...139,747,080
Ensembl chr 3:147,289,205...147,338,600
JBrowse link
G PLS3 plastin 3 ISO RGD PMID:12378542 RGD:731234 NCBI chr  X:104,656,110...104,745,702
Ensembl chr  X:115,160,032...115,250,144
JBrowse link
G PROM1 prominin 1 located_in ISO (PMID:15316084) MGI PMID:15316084 NCBI chr 4:10,405,299...10,519,518
Ensembl chr 4:15,702,159...15,815,454
JBrowse link
G PVALB parvalbumin ISO RGD PMID:16120789 RGD:7175527 NCBI chr22:17,715,109...17,731,587
Ensembl chr22:35,551,448...35,568,316
JBrowse link
G RDX radixin located_in ISO (PMID:17021174) MGI PMID:17021174 NCBI chr11:105,075,716...105,176,660
Ensembl chr11:108,921,477...109,005,557
JBrowse link
G RHOC ras homolog family member C located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:115,353,868...115,360,036
Ensembl chr 1:124,993,063...125,001,708
JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:24,642,239...24,768,074
Ensembl chr 6:24,973,412...25,204,745
JBrowse link
G SLC4A7 solute carrier family 4 member 7 ISO RGD PMID:16301216 RGD:8548636 NCBI chr 3:27,261,155...27,373,223
Ensembl chr 3:27,591,639...27,670,815
JBrowse link
G STX4 syntaxin 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,917,576...23,933,884
Ensembl chr16:31,400,915...31,411,364
JBrowse link
G TMC1 transmembrane channel like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,974,326...52,200,228
Ensembl chr 9:71,400,783...71,620,858
JBrowse link
G TMC2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr20:2,667,175...2,750,058
Ensembl chr20:2,409,961...2,513,365
JBrowse link
G TPRN taperin located_in ISO (PMID:20170899), (PMID:27269051) UniProt PMID:20170899 PMID:27269051 NCBI chr 9:108,251,235...108,261,541 JBrowse link
G TSPEAR thrombospondin type laminin G domain and EAR repeats located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr21:30,791,051...31,005,330
Ensembl chr21:44,087,591...44,299,041
JBrowse link
G USH1C USH1 protein network component harmonin is_active_in
located_in
ISO (PMID:26754646)
(PMID:12485990), (PMID:20016102)
RGD
MGI
PMID:12485990 PMID:16301216 PMID:20016102 PMID:26754646 RGD:8548636 NCBI chr11:17,548,501...17,598,923
Ensembl chr11:17,233,854...17,284,256
JBrowse link
G USH2A usherin ISO hair cell RGD PMID:16301216 RGD:8548636 NCBI chr 1:191,193,130...191,994,664
Ensembl chr 1:196,048,086...196,850,216
JBrowse link
G WHRN whirlin located_in ISO
IEA
RGD
Ensembl
PMID:16434480 GO_REF:0000107 RGD:1600128 NCBI chr 9:85,500,222...85,604,417
Ensembl chr 9:113,863,872...113,966,758
JBrowse link
G ZSWIM6 zinc finger SWIM-type containing 6 located_in ISO (PMID:25105228) MGI PMID:25105228 NCBI chr 5:52,453,762...52,664,847
Ensembl chr 5:54,096,958...54,305,965
JBrowse link
stereocilium base term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLIC5 chloride intracellular channel 5 located_in ISO PMID:24285636
(PMID:37952086)
UniProt PMID:24285636 PMID:37952086 RGD:401966878 NCBI chr 6:45,474,797...45,592,407
Ensembl chr 6:46,753,013...46,934,100
JBrowse link
G GRXCR2 glutaredoxin and cysteine rich domain containing 2 located_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 5:141,309,249...141,322,523
Ensembl chr 5:147,324,358...147,337,633
JBrowse link
G MYO7A myosin VIIA located_in IEA Ensembl GO_REF:0000107 NCBI chr11:72,187,024...72,265,931
Ensembl chr11:75,834,185...75,907,752
JBrowse link
G PJVK pejvakin located_in IEA Ensembl GO_REF:0000107 NCBI chr2B:65,708,635...65,725,766
Ensembl chr2B:183,413,265...183,423,224
JBrowse link
G PTPRQ protein tyrosine phosphatase receptor type Q located_in IEA Ensembl GO_REF:0000107 NCBI chr12:77,957,758...78,200,206
Ensembl chr12:81,068,545...81,310,857
JBrowse link
G RDX radixin located_in ISO (PMID:24285636), (PMID:30159668) UniProt PMID:24285636 PMID:30159668 NCBI chr11:105,075,716...105,176,660
Ensembl chr11:108,921,477...109,005,557
JBrowse link
G TPRN taperin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:108,251,235...108,261,541 JBrowse link
G TRIOBP TRIO and F-actin binding protein located_in IEA Ensembl GO_REF:0000107 NCBI chr22:18,662,794...18,693,138
Ensembl chr22:36,451,860...36,522,391
JBrowse link
stereocilium coat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKHD1L1 PKHD1 like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:106,012,498...106,180,653
Ensembl chr 8:108,158,087...108,322,665
JBrowse link
stereocilium membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1B calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:10408625 RGD:11556226 (All species) (All species) NCBI chr 9:108,989,621...109,256,841 JBrowse link
G MYO1C myosin IC located_in IEA UniProt GO_REF:0000044 NCBI chr17:1,446,506...1,475,634
Ensembl chr17:1,345,143...1,375,540
JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 located_in IEA UniProt GO_REF:0000044 NCBI chr 6:24,642,239...24,768,074
Ensembl chr 6:24,973,412...25,204,745
JBrowse link
G USH2A usherin located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:191,193,130...191,994,664
Ensembl chr 1:196,048,086...196,850,216
JBrowse link
stereocilium shaft term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCHSD2 FCH and double SH3 domains 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,915,796...68,219,482 JBrowse link
G GRXCR2 glutaredoxin and cysteine rich domain containing 2 located_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 5:141,309,249...141,322,523
Ensembl chr 5:147,324,358...147,337,633
JBrowse link
stereocilium tip term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC14A cell division cycle 14A located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:103,002,408...103,178,622
Ensembl chr 1:101,724,213...101,892,619
JBrowse link
G CEACAM16 CEA cell adhesion molecule 16, tectorial membrane component located_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,649,625...41,659,151
Ensembl chr19:50,254,123...50,262,808
JBrowse link
G CORO1A coronin 1A is_active_in ISO (PMID:26754646) MGI PMID:26754646 Ensembl chr16:30,550,383...30,556,196 JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor located_in IEA Ensembl GO_REF:0000107 NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117
JBrowse link
G EPS8L2 EPS8 signaling adaptor L2 located_in IEA Ensembl GO_REF:0000107 NCBI chr11:720,528...741,623
Ensembl chr11:765,689...787,128
JBrowse link
G ESPN espin is_active_in
located_in
ISO (PMID:26754646)
(PMID:22264607), (PMID:26754646)
MGI PMID:22264607 PMID:26754646 NCBI chr 1:5,184,666...5,222,473 JBrowse link
G ESPNL espin like located_in
is_active_in
IEA
ISO
(PMID:26754646) Ensembl
MGI
PMID:26754646 GO_REF:0000107 NCBI chr2B:125,331,809...125,364,719
Ensembl chr2B:244,182,781...244,214,009
JBrowse link
G HOMER2 homer scaffold protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:62,617,905...62,762,903
Ensembl chr15:80,737,570...80,784,729
JBrowse link
G LHFPL5 LHFPL tetraspan subfamily member 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:35,367,304...35,389,595
Ensembl chr 6:36,569,008...36,589,102
JBrowse link
G LOC100983880 cadherin-23 located_in IEA Ensembl GO_REF:0000107 NCBI chr10:67,866,979...68,286,008
Ensembl chr10:70,434,801...70,810,240
JBrowse link
G LOC103785466 stereocilin located_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr15:22,660,952...22,706,416
Ensembl chr15:40,740,387...40,757,999
JBrowse link
G MORN4 MORN repeat containing 4 located_in
is_active_in
IEA
ISO
(PMID:26754646) Ensembl
MGI
PMID:26754646 GO_REF:0000107 NCBI chr10:94,235,061...94,254,509 JBrowse link
G MYO3A myosin IIIA is_active_in
located_in
ISO
IEA
(PMID:26754646) MGI
TreeGrafter
PMID:26754646 GO_REF:0000118 NCBI chr10:26,104,588...26,389,942
Ensembl chr10:26,469,742...26,754,989
JBrowse link
G MYO3B myosin IIIB is_active_in
located_in
ISO
IEA
(PMID:26754646) MGI
TreeGrafter
PMID:26754646 GO_REF:0000118 NCBI chr2B:57,458,046...57,940,039
Ensembl chr2B:174,975,796...175,398,203
JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:68,694,468...68,715,157
Ensembl chr17:74,250,406...74,271,234
JBrowse link
G PDZD7 PDZ domain containing 7 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:97,608,969...97,632,508
Ensembl chr10:101,085,370...101,107,034
JBrowse link
G PKHD1L1 PKHD1 like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:106,012,498...106,180,653
Ensembl chr 8:108,158,087...108,322,665
JBrowse link
G STRC stereocilin located_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr15:22,562,313...22,633,064
Ensembl chr15:40,769,539...40,795,723
Ensembl chr15:40,769,539...40,795,723
JBrowse link
G TMC1 transmembrane channel like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,974,326...52,200,228
Ensembl chr 9:71,400,783...71,620,858
JBrowse link
G TMC2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr20:2,667,175...2,750,058
Ensembl chr20:2,409,961...2,513,365
JBrowse link
G USH1C USH1 protein network component harmonin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:17,548,501...17,598,923
Ensembl chr11:17,233,854...17,284,256
JBrowse link
G WHRN whirlin located_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 9:85,500,222...85,604,417
Ensembl chr 9:113,863,872...113,966,758
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17451
    cellular anatomical structure 17227
      organelle 12702
        stereocilium 67
          actin filament bundle of stereocilium 0
          stereocilium base 8
          stereocilium coat 1
          stereocilium membrane 4
          stereocilium shaft 2
          stereocilium tip 22
Path 2
Term Annotations click to browse term
  cellular_component 17451
    cellular anatomical structure 17227
      cell projection 2456
        plasma membrane bounded cell projection 2389
          neuron projection 1490
            stereocilium 67
              actin filament bundle of stereocilium 0
              stereocilium base 8
              stereocilium coat 1
              stereocilium membrane 4
              stereocilium shaft 2
              stereocilium tip 22
paths to the root