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ONTOLOGY REPORT - ANNOTATIONS
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Term:
MutLalpha complex
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Accession:
GO:0032389
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Definition:
A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
Synonyms:
exact_synonym:
MLH1/PMS2 complex; MutL-alpha complex
broad_synonym:
MMR complex
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Rat (3)
Mouse (3)
Human (3)
Chinchilla (2)
Bonobo (3)
Dog (2)
Squirrel (3)
Pig (2)
Green Monkey (3)
Naked Mole-rat (2)
All
Genes (3)
MutLalpha complex
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Mlh1
mutL homolog 1
part_of
IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
(PMID:16713580), (PMID:22164254)
Ensembl
GO_Central
RGD
PMID:16713580
PMID:22164254
GO_REF:0000033 GO_REF:0000107
NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
G
Pms1
PMS1 homolog 1, mismatch repair system component
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237
G
Pms2
PMS1 homolog 2, mismatch repair system component
part_of
IBA
ISO
GO_REF:0000033
(PMID:16713580)
GO_Central
RGD
PMID:16713580
GO_REF:0000033
NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066
Term paths to the root
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one longest
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Path 1
Term
Annotations
cellular_component
20832
protein-containing complex
6557
mismatch repair complex
7
MutLalpha complex
3
Path 2
Term
Annotations
cellular_component
20832
cellular anatomical structure
20632
organelle
13974
membrane-bounded organelle
12560
intracellular membrane-bounded organelle
12009
nucleus
7454
nuclear protein-containing complex
1275
MutLalpha complex
3