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ONTOLOGY REPORT - ANNOTATIONS


Term:aldosterone biosynthetic process
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Accession:GO:0032342 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.



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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,427...40,695,177
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:1686470), (PMID:8645611) GO_Central
MGI
PMID:1686470 PMID:8645611 GO_REF:0000033 NCBI chr 4:1,365,725...1,373,138 JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:47,385,244...47,444,664
Ensembl chr 2:47,385,192...47,444,660
JBrowse link
G LOC100621006 RE1-silencing transcription factor-like involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
G REST RE1 silencing transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:56,035,182...56,061,140
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270
JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr 6:80,110,238...80,138,165 JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:122,234,731...122,249,889
Ensembl chr13:122,234,736...122,249,867
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18954
    cellular process 18495
      metabolic process 11730
        biosynthetic process 8553
          aldehyde biosynthetic process 19
            aldosterone biosynthetic process 11
              negative regulation of aldosterone biosynthetic process 5
              positive regulation of aldosterone biosynthetic process 3
              regulation of aldosterone biosynthetic process + 9
Path 2
Term Annotations click to browse term
  biological_process 18954
    cellular process 18495
      metabolic process 11730
        primary metabolic process 10388
          lipid metabolic process 1339
            steroid metabolic process 313
              steroid biosynthetic process 166
                steroid hormone biosynthetic process 42
                  mineralocorticoid biosynthetic process 11
                    aldosterone biosynthetic process 11
                      negative regulation of aldosterone biosynthetic process 5
                      positive regulation of aldosterone biosynthetic process 3
                      regulation of aldosterone biosynthetic process + 9
paths to the root