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ONTOLOGY REPORT - ANNOTATIONS


Term:aldosterone biosynthetic process
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Accession:GO:0032342 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.



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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,510,129...39,533,129
Ensembl chr 6:39,510,121...39,533,753
JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:1686470), (PMID:8645611) MGI
GO_Central
PMID:1686470 PMID:8645611 GO_REF:0000033 NCBI chr13:36,866,476...36,880,625 JBrowse link
G LOC119876933 cytochrome P450 11B1, mitochondrial-like involved_in IBA GO_Central GO_REF:0000033
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:35,032,501...35,074,664
Ensembl chr21:35,033,552...35,074,664
JBrowse link
G REST RE1 silencing transcription factor involved_in ISO PMID:19342457
(PMID:19342457)
UniProt PMID:19342457 RGD:4891166 NCBI chr13:49,041,082...49,062,596
Ensembl chr13:49,041,047...49,059,388
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845
JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321
JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,224,136...17,238,755
Ensembl chr34:17,223,215...17,239,621
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22121
    cellular process 21652
      metabolic process 15394
        biosynthetic process 12087
          aldehyde biosynthetic process 19
            aldosterone biosynthetic process 11
              negative regulation of aldosterone biosynthetic process 4
              positive regulation of aldosterone biosynthetic process 3
              regulation of aldosterone biosynthetic process + 8
Path 2
Term Annotations click to browse term
  biological_process 22121
    cellular process 21652
      metabolic process 15394
        primary metabolic process 13985
          lipid metabolic process 1351
            steroid metabolic process 316
              steroid biosynthetic process 169
                steroid hormone biosynthetic process 43
                  mineralocorticoid biosynthetic process 11
                    aldosterone biosynthetic process 11
                      negative regulation of aldosterone biosynthetic process 4
                      positive regulation of aldosterone biosynthetic process 3
                      regulation of aldosterone biosynthetic process + 8
paths to the root