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ONTOLOGY REPORT - ANNOTATIONS


Term:aldosterone biosynthetic process
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Accession:GO:0032342 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.


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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in ISO PMID:19342457
(PMID:19342457)
UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004955442:16,047,965...16,108,862
Ensembl chrNW_004955442:16,045,895...16,108,862
JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955411:450,674...557,213
Ensembl chrNW_004955411:450,674...558,650
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004955414:27,466,636...27,507,186
Ensembl chrNW_004955414:27,456,770...27,508,109
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) UniProt PMID:16527843 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377
JBrowse link
G Dab2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chrNW_004955426:23,852,752...23,883,030 JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO (PMID:29403011) UniProt PMID:29403011 NCBI chrNW_004955420:23,138,558...23,152,462
Ensembl chrNW_004955420:23,138,605...23,152,311
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12561
    cellular process 12000
      metabolic process 7927
        biosynthetic process 5494
          aldehyde biosynthetic process 15
            aldosterone biosynthetic process 8
              negative regulation of aldosterone biosynthetic process 3
              positive regulation of aldosterone biosynthetic process 3
              regulation of aldosterone biosynthetic process + 7
Path 2
Term Annotations click to browse term
  biological_process 12561
    cellular process 12000
      metabolic process 7927
        primary metabolic process 6946
          lipid metabolic process 999
            steroid metabolic process 238
              steroid biosynthetic process 122
                steroid hormone biosynthetic process 33
                  mineralocorticoid biosynthetic process 8
                    aldosterone biosynthetic process 8
                      negative regulation of aldosterone biosynthetic process 3
                      positive regulation of aldosterone biosynthetic process 3
                      regulation of aldosterone biosynthetic process + 7
paths to the root