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ONTOLOGY REPORT - ANNOTATIONS

Term:aldosterone metabolic process
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Accession:GO:0032341 term browser browse the term
Definition:The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
Synonyms:exact_synonym: aldosterone metabolism


show annotations for term's descendants           Sort by:
aldosterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednrb endothelin receptor type B involved_in IEA
ISO 		GO_REF:0000107
MGI:3693642 (PMID:16868309) 		Ensembl
RGD		 PMID:16868309 GO_REF:0000107 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta acts_upstream_of_or_within ISO (PMID:28567665) RGD PMID:28567665 NCBI chr 1:185,861,326...185,915,717
Ensembl chr 1:185,854,733...185,916,049 		JBrowse link
aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in IMP
IEA
ISO 		PMID:19342457
GO_REF:0000107
(PMID:19342457) 		Ensembl
RGD		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IMP
IBA 		PMID:19342457
GO_REF:0000033 		GO_Central PMID:19342457 GO_REF:0000033, RGD:4891166 NCBI chr 7:108,653,385...108,660,062
Ensembl chr 7:108,653,378...108,660,995
Ensembl chr 7:108,653,378...108,660,995 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 acts_upstream_of_or_within
involved_in 		IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:19342457), (PMID:2256920) 		Ensembl
GO_Central
RGD		 PMID:2256920 PMID:19342457 PMID:11832364 GO_REF:0000033 GO_REF:0000107, RGD:727991 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:1741400), (PMID:19342457), (PMID:2256920), (PMID:23322723)
(PMID:1686470), (PMID:8645611)
GO_REF:0000107 		RGD
Ensembl		 PMID:1686470 PMID:1741400 PMID:2256920 PMID:8645611 PMID:19342457 More... GO_REF:0000107 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:19584291) 		Ensembl
RGD		 PMID:19584291 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP 		(PMID:19342457)
GO_REF:0000107 		RGD
Ensembl		 PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:31,213,415...31,233,451
Ensembl chr14:31,213,415...31,248,662 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO
IEA 		(PMID:16527843)
GO_REF:0000107 		RGD
Ensembl		 PMID:16527843 GO_REF:0000107 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261 		JBrowse link
G Dab2 DAB adaptor protein 2 IDA RGD PMID:17303656 RGD:7243836 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA 		(PMID:16981135)
GO_REF:0000107 		RGD
Ensembl		 PMID:16981135 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO
IEA
ISS 		(PMID:29403011)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:29403011 GO_REF:0000024 GO_REF:0000107 NCBI chr11:93,702,382...93,716,059
Ensembl chr11:93,702,360...93,716,059 		JBrowse link
regulation of aldosterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 acts_upstream_of_or_within ISO MGI:3050114 (PMID:17122062) RGD PMID:17122062 NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        ketone metabolic process 265
          aldosterone metabolic process 15
            aldosterone biosynthetic process + 12
            aldosterone catabolic process 0
            regulation of aldosterone metabolic process + 9
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        primary metabolic process 10162
          lipid metabolic process 1489
            steroid metabolic process 377
              mineralocorticoid metabolic process 17
                aldosterone metabolic process 15
                  aldosterone biosynthetic process + 12
                  aldosterone catabolic process 0
                  regulation of aldosterone metabolic process + 9
paths to the root