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ONTOLOGY REPORT - ANNOTATIONS

Term:phospholipase D-activating G protein-coupled receptor signaling pathway
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Accession:GO:0031583 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase D (PLD) and a subsequent increase in the intracellular concentration of phosphatidic acid (PA).
Comment:This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase D (PLD) activation.
Synonyms:exact_synonym: G-protein signalling, phospholipase D activating pathway
 related_synonym: activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway


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phospholipase D-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein acts_upstream_of_positive_effect ISO (PMID:18723082) RGD PMID:18723082 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Edn1 endothelin 1 acts_upstream_of_or_within ISO (PMID:8978712) RGD PMID:8978712 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:12435801 RGD:1598460 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      signal transduction 7183
        G protein-coupled receptor signaling pathway 2447
          phospholipase D-activating G protein-coupled receptor signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 20076
    biological regulation 13559
      regulation of biological process 13136
        signaling 7744
          signal transduction 7183
            G protein-coupled receptor signaling pathway 2447
              phospholipase D-activating G protein-coupled receptor signaling pathway 3
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