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ONTOLOGY REPORT - ANNOTATIONS


Term:PcG protein complex
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Accession:GO:0031519 term browser browse the term
Definition:A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
Synonyms:exact_synonym: Polycomb Group protein complex
 never_in_taxon: NCBITaxon:4890 ! Ascomycota



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PcG protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmi1 BMI1 proto-oncogene, polycomb ring finger part_of ISO (PMID:21282530), (PMID:26151332)
(PMID:16624538)
RGD PMID:16624538 PMID:21282530 PMID:26151332 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Cbx2 chromobox 2 part_of ISO (PMID:21282530)
(PMID:17001316), (PMID:9312051)
RGD PMID:9312051 PMID:17001316 PMID:21282530 NCBI chr10:104,278,517...104,287,384
Ensembl chr10:104,278,549...104,287,383
JBrowse link
G Cbx4 chromobox 4 part_of ISO (PMID:21282530) RGD PMID:21282530 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
JBrowse link
G Cbx6 chromobox 6 part_of ISO (PMID:21282530) RGD PMID:21282530 NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091
JBrowse link
G Cbx7 chromobox 7 part_of ISS
ISO
GO_REF:0000024
(PMID:21282530)
UniProt
RGD
PMID:21282530 GO_REF:0000024 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Cbx8 chromobox 8 part_of ISO (PMID:21282530) RGD PMID:21282530 NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 located_in ISS
ISO
GO_REF:0000024
(PMID:21282530)
UniProt
RGD
PMID:21282530 GO_REF:0000024 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 located_in ISO (PMID:21282530) RGD PMID:21282530 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
JBrowse link
G Csnk2b casein kinase 2 beta part_of
located_in
IEA
ISO
ISS
GO_REF:0000107
(PMID:21282530)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21282530 GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Kdm2b lysine demethylase 2B part_of ISO (PMID:16943429) RGD PMID:16943429 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355
JBrowse link
G Pcgf1 polycomb group ring finger 1 part_of ISO
IEA
ISS
(PMID:16943429), (PMID:21282530), (PMID:26151332)
(PMID:28596365)
GO_REF:0000117
GO_REF:0000024
RGD
UniProt
PMID:16943429 PMID:21282530 PMID:26151332 PMID:28596365 GO_REF:0000024 GO_REF:0000117 NCBI chr 4:115,576,165...115,587,019
Ensembl chr 4:115,583,867...115,587,008
JBrowse link
G Pcgf2 polycomb group ring finger 2 part_of ISO (PMID:21282530), (PMID:26151332)
(PMID:28596365)
RGD PMID:21282530 PMID:26151332 PMID:28596365 NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406
JBrowse link
G Pcgf3 polycomb group ring finger 3 part_of ISO (PMID:21282530)
(PMID:28596365)
RGD PMID:21282530 PMID:28596365 NCBI chr14:1,237,594...1,291,717
Ensembl chr14:1,233,947...1,291,793
JBrowse link
G Pcgf5 polycomb group ring finger 5 part_of ISO (PMID:21282530)
(PMID:28596365)
RGD PMID:21282530 PMID:28596365 NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
JBrowse link
G Pcgf6 polycomb group ring finger 6 part_of ISO
IEA
ISS
(PMID:21282530), (PMID:26151332)
GO_REF:0000117
(PMID:28596365)
GO_REF:0000024
RGD
UniProt
PMID:21282530 PMID:26151332 PMID:28596365 GO_REF:0000024 GO_REF:0000117 NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
JBrowse link
G Pcgf6l1 polycomb group RING finger protein 6 like 1 part_of IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  X:73,506,495...73,507,638
Ensembl chr  X:73,506,495...73,507,638
JBrowse link
G Phc1 polyhomeotic homolog 1 part_of ISO (PMID:21282530) RGD PMID:21282530 NCBI chr 4:155,510,274...155,532,636
Ensembl chr 4:155,510,274...155,533,959
JBrowse link
G Phc2 polyhomeotic homolog 2 part_of ISO (PMID:21282530) RGD PMID:21282530 NCBI chr 5:141,000,604...141,099,268
Ensembl chr 5:141,050,842...141,099,268
JBrowse link
G Phc3 polyhomeotic homolog 3 part_of ISO (PMID:21282530)
(PMID:17001316)
RGD PMID:17001316 PMID:21282530 NCBI chr 2:112,408,709...112,483,719
Ensembl chr 2:112,408,531...112,476,540
JBrowse link
G Ring1 ring finger protein 1 part_of ISS
ISO
IBA
GO_REF:0000024
(PMID:16624538), (PMID:9312051)
GO_REF:0000033
(PMID:16943429), (PMID:21282530)
UniProt
RGD
GO_Central
PMID:9312051 PMID:16624538 PMID:16943429 PMID:21282530 GO_REF:0000024 GO_REF:0000033 NCBI chr20:4,830,120...4,833,623
Ensembl chr20:4,830,053...4,833,620
JBrowse link
G Rnf2 ring finger protein 2 part_of ISO
IBA
ISS
(PMID:16943429), (PMID:21282530)
(PMID:16624538), (PMID:28596365)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:16624538 PMID:16943429 PMID:21282530 PMID:28596365 GO_REF:0000024 GO_REF:0000033 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
JBrowse link
G Rybp RING1 and YY1 binding protein part_of ISO (PMID:16943429) RGD PMID:16943429 NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316
JBrowse link
G Scml2 Scm polycomb group protein like 2 part_of ISO (PMID:21282530) RGD PMID:21282530 NCBI chr  X:33,523,179...33,677,672
Ensembl chr  X:33,524,530...33,652,742
JBrowse link
G Skp1 S-phase kinase-associated protein 1 part_of IEA
ISO
GO_REF:0000107
(PMID:16943429)
Ensembl
RGD
PMID:16943429 GO_REF:0000107 NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388
JBrowse link
G Ubap2l ubiquitin associated protein 2-like part_of ISO (PMID:25185265) RGD PMID:25185265 NCBI chr 2:175,438,703...175,494,085
Ensembl chr 2:175,438,703...175,493,998
JBrowse link
G Yy1 YY1 transcription factor part_of IBA
ISO
GO_REF:0000033
(PMID:16624538), (PMID:17001316)
GO_Central
RGD
PMID:16624538 PMID:17001316 GO_REF:0000033 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Yy2 YY2 transcription factor part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:37,438,425...37,442,047
Ensembl chr  X:37,410,811...37,464,430
JBrowse link
ESC/E(Z) complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aebp2 AE binding protein 2 part_of ISO
IBA
(PMID:20075857)
(PMID:20064375), (PMID:20064376), (PMID:31451685)
GO_REF:0000033
RGD
GO_Central
PMID:20064375 PMID:20064376 PMID:20075857 PMID:31451685 GO_REF:0000033 NCBI chr 4:173,527,881...173,566,033
Ensembl chr 4:173,528,344...173,593,100
JBrowse link
G Dnmt3l DNA methyltransferase 3 like part_of
located_in
IEA
ISO
ISS
GO_REF:0000107
(PMID:24074865)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24074865 GO_REF:0000024 GO_REF:0000107 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516
JBrowse link
G Eed embryonic ectoderm development part_of ISO
IBA
(PMID:15385962), (PMID:20075857), (PMID:23104054), (PMID:23273982)
(PMID:20064375), (PMID:20064376), (PMID:20144788), (PMID:22438827), (PMID:31451685)
GO_REF:0000033
RGD
GO_Central
PMID:15385962 PMID:20064375 PMID:20064376 PMID:20075857 PMID:20144788 More... GO_REF:0000033 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
JBrowse link
G Epop elongin BC and polycomb repressive complex 2 associated protein part_of ISO (PMID:27863225) RGD PMID:27863225 NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit part_of ISO
IBA
(PMID:20075857)
(PMID:19026781), (PMID:20064376), (PMID:20144788), (PMID:22438827), (PMID:31451685)
GO_REF:0000033
RGD
GO_Central
PMID:19026781 PMID:20064376 PMID:20075857 PMID:20144788 PMID:22438827 More... GO_REF:0000033 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit part_of ISO
IBA
(PMID:15385962), (PMID:20075857), (PMID:23104054), (PMID:23273982), (PMID:24474760)
(PMID:19026781), (PMID:20064375), (PMID:20064376), (PMID:20144788), (PMID:22438827), (PMID:23160351), (PMID:31451685)
GO_REF:0000033
RGD
GO_Central
PMID:15385962 PMID:19026781 PMID:20064375 PMID:20064376 PMID:20075857 More... GO_REF:0000033 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Hdac2 histone deacetylase 2 part_of ISO (PMID:20075857) RGD PMID:20075857 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 part_of ISO (PMID:20064375), (PMID:20064376), (PMID:31451685) RGD PMID:20064375 PMID:20064376 PMID:31451685 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690
JBrowse link
G Mtf2 metal response element binding transcription factor 2 part_of ISO (PMID:20144788) RGD PMID:20144788 NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524
JBrowse link
G Phf1 PHD finger protein 1 located_in
part_of
ISO (PMID:23273982)
(PMID:31451685)
RGD PMID:23273982 PMID:31451685 NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871
JBrowse link
G Phf19 PHD finger protein 19 located_in
part_of
ISO (PMID:23104054)
(PMID:22438827), (PMID:23160351)
RGD PMID:22438827 PMID:23104054 PMID:23160351 NCBI chr 3:18,175,281...18,197,289
Ensembl chr 3:18,175,282...18,196,405
JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor part_of ISO
IBA
(PMID:20075857), (PMID:23104054), (PMID:23273982)
(PMID:20064376), (PMID:31451685)
GO_REF:0000033
RGD
GO_Central
PMID:20064376 PMID:20075857 PMID:23104054 PMID:23273982 PMID:31451685 GO_REF:0000033 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284
JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor part_of ISS
ISO
IBA
GO_REF:0000024
(PMID:31451685)
GO_REF:0000033
(PMID:20075857), (PMID:23104054), (PMID:23273982)
UniProt
RGD
GO_Central
PMID:20075857 PMID:23104054 PMID:23273982 PMID:31451685 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:31,913,080...31,931,245
Ensembl chr  X:31,913,081...31,931,226
JBrowse link
G Sirt1 sirtuin 1 located_in
part_of
ISO
IEA
(PMID:15684044)
GO_REF:0000107
RGD
Ensembl
PMID:15684044 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit part_of ISO
IBA
(PMID:15385962), (PMID:20075857), (PMID:23104054), (PMID:23273982)
(PMID:20064375), (PMID:20064376), (PMID:20144788), (PMID:22438827), (PMID:23160351), (PMID:31451685)
GO_REF:0000033
RGD
GO_Central
PMID:15385962 PMID:20064375 PMID:20064376 PMID:20075857 PMID:20144788 More... GO_REF:0000033 NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738
JBrowse link
G Trim37 tripartite motif-containing 37 located_in
part_of
ISO
IBA
(PMID:25470042)
GO_REF:0000033
RGD
GO_Central
PMID:25470042 GO_REF:0000033 NCBI chr10:71,943,384...72,075,563
Ensembl chr10:71,943,375...72,075,558
JBrowse link
PR-DUB complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asxl1 ASXL transcriptional regulator 1 part_of ISO
IBA
(PMID:20436459)
GO_REF:0000033
RGD
GO_Central
PMID:20436459 GO_REF:0000033 NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538
JBrowse link
G Asxl2 ASXL transcriptional regulator 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477
JBrowse link
G Asxl3 ASXL transcriptional regulator 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:13,593,529...13,766,324
Ensembl chr18:13,593,985...13,762,427
JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 part_of ISO
IEA
ISS
(PMID:20436459), (PMID:25451922)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20436459 PMID:25451922 GO_REF:0000024 GO_REF:0000107 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
PRC1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmi1 BMI1 proto-oncogene, polycomb ring finger part_of ISO
IBA
(PMID:12167701), (PMID:19636380)
(PMID:16359901)
GO_REF:0000033
RGD
GO_Central
PMID:12167701 PMID:16359901 PMID:19636380 GO_REF:0000033 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Cbx2 chromobox 2 part_of ISO
IBA
(PMID:12167701), (PMID:19636380)
GO_REF:0000033
RGD
GO_Central
PMID:12167701 PMID:19636380 GO_REF:0000033 NCBI chr10:104,278,517...104,287,384
Ensembl chr10:104,278,549...104,287,383
JBrowse link
G Cbx4 chromobox 4 part_of ISO
IBA
(PMID:12167701), (PMID:19636380)
GO_REF:0000033
RGD
GO_Central
PMID:12167701 PMID:19636380 GO_REF:0000033 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
JBrowse link
G Cbx6 chromobox 6 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091
JBrowse link
G Cbx7 chromobox 7 part_of ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000002
(PMID:19636380)
UniProt
InterPro
RGD
PMID:19636380 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Cbx8 chromobox 8 part_of ISO
IBA
(PMID:12167701), (PMID:19636380)
(PMID:16359901)
GO_REF:0000033
RGD
GO_Central
PMID:12167701 PMID:16359901 PMID:19636380 GO_REF:0000033 NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024
JBrowse link
G Pcgf1 polycomb group ring finger 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:115,576,165...115,587,019
Ensembl chr 4:115,583,867...115,587,008
JBrowse link
G Pcgf2 polycomb group ring finger 2 part_of ISO
IBA
(PMID:19636380)
(PMID:16359901)
GO_REF:0000033
RGD
GO_Central
PMID:16359901 PMID:19636380 GO_REF:0000033 NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406
JBrowse link
G Pcgf3 polycomb group ring finger 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:1,237,594...1,291,717
Ensembl chr14:1,233,947...1,291,793
JBrowse link
G Pcgf5 polycomb group ring finger 5 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
JBrowse link
G Pcgf6 polycomb group ring finger 6 part_of ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:19636380)
UniProt
GO_Central
RGD
PMID:19636380 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
JBrowse link
G Phc1 polyhomeotic homolog 1 part_of ISO
IBA
(PMID:12167701), (PMID:19636380)
GO_REF:0000033
RGD
GO_Central
PMID:12167701 PMID:19636380 GO_REF:0000033 NCBI chr 4:155,510,274...155,532,636
Ensembl chr 4:155,510,274...155,533,959
JBrowse link
G Phc2 polyhomeotic homolog 2 part_of ISO
IBA
(PMID:12167701), (PMID:19636380)
GO_REF:0000033
(PMID:16359901)
RGD
GO_Central
PMID:12167701 PMID:16359901 PMID:19636380 GO_REF:0000033 NCBI chr 5:141,000,604...141,099,268
Ensembl chr 5:141,050,842...141,099,268
JBrowse link
G Phc3 polyhomeotic homolog 3 part_of ISO
IBA
(PMID:12167701), (PMID:19636380)
GO_REF:0000033
RGD
GO_Central
PMID:12167701 PMID:19636380 GO_REF:0000033 NCBI chr 2:112,408,709...112,483,719
Ensembl chr 2:112,408,531...112,476,540
JBrowse link
G Ring1 ring finger protein 1 part_of ISS
ISO
IEA
GO_REF:0000024
(PMID:12167701), (PMID:19636380)
GO_REF:0000107
(PMID:16359901)
UniProt
RGD
Ensembl
PMID:12167701 PMID:16359901 PMID:19636380 GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,830,120...4,833,623
Ensembl chr20:4,830,053...4,833,620
JBrowse link
G Rnf2 ring finger protein 2 part_of ISO
IEA
ISS
(PMID:12167701), (PMID:19636380)
(PMID:16359901)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12167701 PMID:16359901 PMID:19636380 GO_REF:0000024 GO_REF:0000107 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
JBrowse link
G Samd11 sterile alpha motif domain containing 11 part_of ISO (PMID:33603070) RGD PMID:33603070 NCBI chr 5:166,831,681...166,859,805
Ensembl chr 5:166,831,663...166,850,009
JBrowse link
G Samd7 sterile alpha motif domain containing 7 part_of ISO (PMID:28900001), (PMID:33603070) RGD PMID:28900001 PMID:33603070 NCBI chr 2:112,623,135...112,644,269
Ensembl chr 2:112,624,942...112,639,549
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20824
    protein-containing complex 6552
      nuclear protein-containing complex 1279
        PcG protein complex 49
          ESC/E(Z) complex 16
          PR-DUB complex 4
          PRC1 complex 18
Path 2
Term Annotations click to browse term
  cellular_component 20824
    cellular anatomical structure 20625
      organelle 13967
        membrane-bounded organelle 12555
          intracellular membrane-bounded organelle 12003
            nucleus 7451
              nuclear protein-containing complex 1279
                PcG protein complex 49
                  ESC/E(Z) complex 16
                  PR-DUB complex 4
                  PRC1 complex 18
paths to the root