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ONTOLOGY REPORT - ANNOTATIONS


Term:TRAMP complex
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Accession:GO:0031499 term browser browse the term
Definition:A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
Synonyms:narrow_synonym: TRAMP4 complex;   TRAMP5 complex;   Trf4 complex;   Trf4 poly(A) polymerase complex;   Trf4p-Air2p-Mtr4p polyadenylation complex
 xref: Wikipedia:TRAMP_complex



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TRAMP complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtrex Mtr4 exosome RNA helicase part_of ISO
IBA
(PMID:21855801)
GO_REF:0000033
RGD
GO_Central
PMID:21855801 GO_REF:0000033 NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627
JBrowse link
G Tent4a terminal nucleotidyltransferase 4A part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:33,765,949...33,799,405
Ensembl chr 1:33,765,672...33,799,433
JBrowse link
G Tent4b terminal nucleotidyltransferase 4B part_of ISO
IBA
(PMID:21855801)
GO_REF:0000033
RGD
GO_Central
PMID:21855801 GO_REF:0000033 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537
JBrowse link
G Zcchc7 zinc finger CCHC-type containing 7 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:58,992,558...59,173,308
Ensembl chr 5:58,993,290...59,173,300
JBrowse link
G Zcchc8 zinc finger CCHC-type containing 8 part_of ISO (PMID:21855801) RGD PMID:21855801 NCBI chr12:32,869,170...32,892,707
Ensembl chr12:32,869,310...32,891,325
JBrowse link

Term paths to the root
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  cellular_component 20824
    protein-containing complex 6552
      nuclear protein-containing complex 1279
        TRAMP complex 5
Path 2
Term Annotations click to browse term
  cellular_component 20824
    cellular anatomical structure 20625
      organelle 13967
        membrane-bounded organelle 12555
          intracellular membrane-bounded organelle 12003
            nucleus 7451
              nuclear protein-containing complex 1279
                TRAMP complex 5
paths to the root