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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell killing
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Accession:GO:0031342 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.
Synonyms:exact_synonym: down regulation of cell killing;   downregulation of cell killing
 narrow_synonym: inhibition of cell killing
 xref: Reactome:R-HSA-9664433 "Leishmania parasite growth and survival"



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negative regulation of complement-dependent cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59b CD59b molecule IMP RGD PMID:28212662 RGD:13792592 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP oligodendrocyte precursor cells RGD PMID:16135098 RGD:10448271 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Il13 interleukin 13 involved_in ISO (PMID:16034134) RGD PMID:16034134 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:16034134)
(PMID:16034134), (PMID:24280217)
RGD PMID:16034134 PMID:24280217 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Stat6 signal transducer and activator of transcription 6 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
negative regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:16732273)
UniProt
RGD
PMID:16732273 GO_REF:0000024 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO
IEA
(PMID:18604210)
GO_REF:0000107
RGD
Ensembl
PMID:18604210 GO_REF:0000107 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Clec12b C-type lectin domain family 12, member B involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:162,827,462...162,843,821
Ensembl chr 4:162,827,462...162,838,946
JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:18835194 RGD:11568650 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:9021955 RGD:9685777 NCBI chr10:14,223,023...14,225,736
Ensembl chr10:13,718,489...13,720,869
JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO
IEA
(PMID:25870599)
GO_REF:0000107
RGD
Ensembl
PMID:25870599 GO_REF:0000107 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Igf2 insulin-like growth factor 2 IDA RGD PMID:9021955 RGD:9685777 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in ISO
IEA
(PMID:23154388)
GO_REF:0000107
RGD
Ensembl
PMID:23154388 GO_REF:0000107 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206), (PMID:9486650) RGD PMID:9485206 PMID:9486650 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IEA
ISS
(PMID:9486650)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:9486650 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:28515320) RGD PMID:28515320 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Nectin4 nectin cell adhesion molecule 4 involved_in ISO (PMID:32503945) RGD PMID:32503945 NCBI chr13:83,802,589...83,821,711
Ensembl chr13:83,803,184...83,821,709
JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:23154388) RGD PMID:23154388 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IMP RGD PMID:10837412 RGD:2313500 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:10190900), (PMID:12874224) RGD PMID:10190900 PMID:12874224 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:3641175 (PMID:16127454) RGD PMID:16127454 NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509
JBrowse link
G Tigit T cell immunoreceptor with Ig and ITIM domains involved_in ISO (PMID:23154388) RGD PMID:23154388 NCBI chr11:57,029,024...57,046,627
Ensembl chr11:57,029,118...57,045,994
JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:23696226)
GO_REF:0000024
RGD
UniProt
PMID:23696226 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Klre1 killer cell lectin like receptor E1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:24586048) RGD PMID:24586048 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (PMID:9215624) RGD PMID:9215624 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206) RGD PMID:9485206 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IEA
ISS
(PMID:9485206)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:9485206 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181294 (PMID:18097009)
Ensembl
RGD
PMID:18097009 GO_REF:0000107 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO
GO_REF:0000024
(PMID:9725213)
UniProt
RGD
PMID:9725213 GO_REF:0000024 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,242 JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec2d C-type lectin domain family 2, member D acts_upstream_of_or_within ISO MGI:107539 (PMID:12858173), (PMID:14990792), (PMID:19535641) RGD PMID:12858173 PMID:14990792 PMID:19535641 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572 PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 NOT|involved_in ISO (PMID:18502829)
(PMID:18502829), (PMID:8839770)
RGD PMID:8839770 PMID:18502829 NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Serpinb3a serpin family B member 3A involved_in ISO (PMID:21857942) RGD PMID:21857942 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      cell killing 243
        negative regulation of cell killing 43
          negative regulation of complement-dependent cytotoxicity 7
          negative regulation of killing of cells of another organism + 0
          negative regulation of leukocyte mediated cytotoxicity + 36
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        regulation of cellular process 13014
          regulation of cell killing 157
            negative regulation of cell killing 43
              negative regulation of complement-dependent cytotoxicity 7
              negative regulation of killing of cells of another organism + 0
              negative regulation of leukocyte mediated cytotoxicity + 36
paths to the root