ONTOLOGY REPORT - ANNOTATIONS
Term: SCAR complex
Accession: GO:0031209
browse the term
Definition: A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.
Synonyms: exact_synonym: WAVE complex; WAVE regulatory complex
broad_synonym: WRC
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Abi1
abl-interactor 1
part_of
ISO IEA IBA
(PMID:21107423), (PMID:26428302) GO_REF:0000107 GO_REF:0000033 (PMID:12672821), (PMID:26428302)
RGD Ensembl GO_Central
PMID:12672821 PMID:21107423 PMID:26428302
GO_REF:0000033 GO_REF:0000107
NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792
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Abi2
abl-interactor 2
part_of
ISO
(PMID:21107423)
RGD
PMID:21107423
NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699
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Abi3
ABI family, member 3
part_of
ISO IBA
(PMID:17101133), (PMID:26428302) GO_REF:0000033 (PMID:26428302)
RGD GO_Central
PMID:17101133 PMID:26428302
GO_REF:0000033
NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816
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Brk1
BRICK1 subunit of SCAR/WAVE actin nucleating complex
part_of
ISO IBA
(PMID:18560548), (PMID:21107423) GO_REF:0000033
RGD GO_Central
PMID:18560548 PMID:21107423
GO_REF:0000033
NCBI chr 4:146,750,821...146,766,050
Ensembl chr 4:146,750,821...146,768,856
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Cyfip1
cytoplasmic FMR1 interacting protein 1
part_of
IBA ISO
GO_REF:0000033 (PMID:18560548), (PMID:21107423)
GO_Central RGD
PMID:18560548 PMID:21107423
GO_REF:0000033
NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
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Cyfip2
cytoplasmic FMR1 interacting protein 2
part_of NOT|part_of
ISO IBA
(PMID:17101133), (PMID:26428302) GO_REF:0000033 (PMID:26428302)
RGD GO_Central
PMID:17101133 PMID:26428302
GO_REF:0000033
NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113
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Nckap1
NCK-associated protein 1
part_of
ISO IEA IBA
(PMID:21107423) GO_REF:0000107 GO_REF:0000033
RGD Ensembl GO_Central
PMID:21107423
GO_REF:0000033 GO_REF:0000107
NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217
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Nckap1l
NCK associated protein 1 like
part_of
ISO ISS IBA
(PMID:16417406) GO_REF:0000024 GO_REF:0000033 (PMID:19015308)
RGD UniProt GO_Central
PMID:16417406 PMID:19015308
GO_REF:0000024 GO_REF:0000033
NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
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Wasf1
WASP family member 1
part_of
ISO IEA IBA
(PMID:21107423) GO_REF:0000107 GO_REF:0000033
RGD Ensembl GO_Central
PMID:21107423
GO_REF:0000033 GO_REF:0000107
NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996
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Wasf2
WASP family member 2
part_of
ISO IBA
(PMID:17101133), (PMID:18560548), (PMID:21107423), (PMID:26428302) GO_REF:0000033 (PMID:26428302)
RGD GO_Central
PMID:17101133 PMID:18560548 PMID:21107423 PMID:26428302
GO_REF:0000033
NCBI chr 5:145,336,817...145,402,041
Ensembl chr 5:145,336,842...145,399,242
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Wasf3
WASP family member 3
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:8,563,805...8,660,799
Ensembl chr12:8,562,062...8,660,751
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Wasfl
WASP family member 1 like
part_of
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr X:73,040,984...73,043,716
Ensembl chr X:73,040,902...73,043,716
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