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ONTOLOGY REPORT - ANNOTATIONS

Term:SCAR complex
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Accession:GO:0031209 term browser browse the term
Definition:A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.
Synonyms:exact_synonym: WAVE complex;   WAVE regulatory complex
 broad_synonym: WRC


show annotations for term's descendants           Sort by:
SCAR complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 part_of ISO
IEA
IBA 		(PMID:21107423), (PMID:26428302)
GO_REF:0000107
GO_REF:0000033
(PMID:12672821), (PMID:26428302) 		RGD
Ensembl
GO_Central		 PMID:12672821 PMID:21107423 PMID:26428302 GO_REF:0000033 GO_REF:0000107 NCBI chr17:90,006,917...90,088,002
Ensembl chr17:90,006,925...90,087,827 		JBrowse link
G Abi2 abl-interactor 2 part_of ISO
IBA 		(PMID:21107423)
GO_REF:0000033 		RGD
GO_Central		 PMID:21107423 GO_REF:0000033 NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:69,321,150...69,490,597 		JBrowse link
G Abi3 ABI family, member 3 part_of ISO
IBA
IEA 		(PMID:17101133), (PMID:26428302)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000117
(PMID:26428302) 		RGD
GO_Central
Ensembl
UniProt		 PMID:17101133 PMID:26428302 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr10:81,266,571...81,277,561
Ensembl chr10:81,266,571...81,277,561 		JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex part_of ISO
IBA
IEA 		(PMID:18560548), (PMID:21107423)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002 		RGD
GO_Central
Ensembl
InterPro		 PMID:18560548 PMID:21107423 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:148,306,436...148,321,668
Ensembl chr 4:148,306,398...148,321,984 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 part_of IBA
ISO 		GO_REF:0000033
(PMID:18560548), (PMID:21107423) 		GO_Central
RGD		 PMID:18560548 PMID:21107423 GO_REF:0000033 NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:115,846,661...115,951,292 		JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 part_of
NOT|part_of 		ISO
IBA 		(PMID:17101133), (PMID:26428302)
GO_REF:0000033
(PMID:26428302) 		RGD
GO_Central		 PMID:17101133 PMID:26428302 GO_REF:0000033 NCBI chr10:31,122,653...31,242,440
Ensembl chr10:31,122,653...31,242,440 		JBrowse link
G Nckap1 NCK-associated protein 1 part_of ISO
IEA
IBA 		(PMID:21107423)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:21107423 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797 		JBrowse link
G Nckap1l NCK associated protein 1 like part_of ISO
ISS
IBA 		(PMID:16417406)
GO_REF:0000024
GO_REF:0000033
(PMID:19015308) 		RGD
UniProt
GO_Central		 PMID:16417406 PMID:19015308 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384 		JBrowse link
G Wasf1 WASP family member 1 part_of ISO
IEA
IBA 		(PMID:21107423)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:21107423 GO_REF:0000033 GO_REF:0000107 NCBI chr20:45,908,458...45,956,118
Ensembl chr20:45,908,750...45,955,640 		JBrowse link
G Wasf2 WASP family member 2 part_of ISO
IBA
IEA 		(PMID:17101133), (PMID:18560548), (PMID:21107423), (PMID:26428302)
GO_REF:0000033
GO_REF:0000107
(PMID:26428302) 		RGD
GO_Central
Ensembl		 PMID:17101133 PMID:18560548 PMID:21107423 PMID:26428302 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:150,620,733...150,685,943 		JBrowse link
G Wasf3 WASP family member 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:13,675,642...13,774,648
Ensembl chr12:13,675,645...13,774,559 		JBrowse link
G Wasfl WASP family member 1 like part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:77,113,760...77,116,492
Ensembl chr  X:77,113,764...77,116,492 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19485
    protein-containing complex 6265
      SCAR complex 12
Path 2
Term Annotations click to browse term
  cellular_component 19485
    cellular anatomical structure 19353
      intracellular anatomical structure 14908
        cytoplasm 11910
          SCAR complex 12
paths to the root