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ONTOLOGY REPORT - ANNOTATIONS

Term:platelet dense tubular network
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Accession:GO:0031094 term browser browse the term
Definition:A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.


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platelet dense tubular network term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2R coagulation factor II thrombin receptor located_in IDA (PMID:9038223) BHF-UCL PMID:9038223 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 located_in IDA (PMID:10828023) BHF-UCL PMID:10828023 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506 		JBrowse link
G SERPINA5 serpin family A member 5 located_in IDA (PMID:9556620) UniProt PMID:9556620 NCBI chr14:94,581,426...94,593,118
Ensembl chr14:94,561,442...94,593,118 		JBrowse link
platelet dense tubular network membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 located_in TAS Reactome Reactome:R-HSA-418365 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 located_in TAS Reactome Reactome:R-HSA-418365 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 located_in TAS Reactome Reactome:R-HSA-418365 NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,868...3,964,464 		JBrowse link
G DMTN dematin actin binding protein located_in IDA (PMID:23060452) UniProt PMID:23060452 NCBI chr 8:22,048,931...22,082,525
Ensembl chr 8:22,048,995...22,082,527 		JBrowse link
G EHD1 EH domain containing 1 located_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:64,851,642...64,879,693
Ensembl chr11:64,851,642...64,888,296 		JBrowse link
G IRAG1 inositol 1,4,5-triphosphate receptor associated 1 located_in TAS Reactome Reactome:R-HSA-418442 NCBI chr11:10,573,095...10,693,755
Ensembl chr11:10,573,091...10,693,988 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 located_in TAS Reactome Reactome:R-HSA-139854 Reactome:R-HSA-139941 Reactome:R-HSA-418442 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 located_in TAS Reactome Reactome:R-HSA-139854 Reactome:R-HSA-139941 NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 located_in TAS Reactome Reactome:R-HSA-139854 Reactome:R-HSA-139941 NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20802
    cellular anatomical structure 20465
      organelle 15677
        membrane-bounded organelle 14748
          intracellular membrane-bounded organelle 13525
            platelet dense tubular network 11
              platelet dense tubular network lumen 0
              platelet dense tubular network membrane 9
paths to the root