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ONTOLOGY REPORT - ANNOTATIONS

Term:platelet alpha granule
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Accession:GO:0031091 term browser browse the term
Definition:A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).
Synonyms:xref: Wikipedia:Platelet_alpha-granule


show annotations for term's descendants           Sort by:
platelet alpha granule term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F5 coagulation factor V located_in ISO
IEA		 (PMID:12816857)
GO_REF:0000107		 RGD
Ensembl		 PMID:12816857 GO_REF:0000107 NCBI chr13:79,046,657...79,116,247
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G Fga fibrinogen alpha chain located_in ISO (PMID:6777381) RGD PMID:6777381 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain located_in ISO
IEA		 (PMID:6777381)
GO_REF:0000107		 RGD
Ensembl		 PMID:6777381 GO_REF:0000107 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain located_in ISO (PMID:6777381) RGD PMID:6777381 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Igf1 insulin-like growth factor 1 IDA RGD PMID:9449625 RGD:10402780 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 IDA RGD PMID:9449625 RGD:10402780 NCBI chr14:86,270,208...86,277,944
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Mmrn1 multimerin 1 located_in ISO
IEA		 (PMID:7642592)
GO_REF:0000107		 RGD
Ensembl		 PMID:7642592 GO_REF:0000107 NCBI chr 4:91,205,462...91,280,862
Ensembl chr 4:89,903,174...89,950,474 		JBrowse link
G Pf4 platelet factor 4 IDA RGD PMID:2379543 RGD:2316766 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Ppbp pro-platelet basic protein located_in ISO (PMID:10877842) RGD PMID:10877842 NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,302,326...17,303,130 		JBrowse link
G Serpina5 serpin family A member 5 located_in ISO (PMID:9556620) RGD PMID:9556620 NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:123,023,306...123,028,407 		JBrowse link
G Serpine2 serpin family E member 2 located_in ISO
IEA		 (PMID:19855083)
GO_REF:0000107		 RGD
Ensembl		 PMID:19855083 GO_REF:0000107 NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sparc secreted protein acidic and cysteine rich located_in ISO
IEA		 (PMID:1737102)
GO_REF:0000107		 RGD
Ensembl		 PMID:1737102 GO_REF:0000107 NCBI chr10:40,017,065...40,038,816
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Stxbp1 syntaxin binding protein 1 located_in ISO
IEA		 (PMID:12773094)
GO_REF:0000107		 RGD
Ensembl		 PMID:12773094 GO_REF:0000107 NCBI chr 3:36,474,428...36,536,120
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Stxbp3 syntaxin binding protein 3 located_in ISO
IEA		 (PMID:12773094)
GO_REF:0000107		 RGD
Ensembl		 PMID:12773094 GO_REF:0000107 NCBI chr 2:199,130,725...199,173,823
Ensembl chr 2:196,442,634...196,485,671 		JBrowse link
G Thbs1 thrombospondin 1 located_in ISO
IEA		 (PMID:6777381)
GO_REF:0000107		 RGD
Ensembl		 PMID:6777381 GO_REF:0000107 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thbs2 thrombospondin 2 located_in ISO
IEA		 (PMID:1737102)
GO_REF:0000107		 RGD
Ensembl		 PMID:1737102 GO_REF:0000107 NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:55,670,394...55,699,789 		JBrowse link
G Treml1 triggering receptor expressed on myeloid cells-like 1 located_in ISO
IEA		 (PMID:15128762)
GO_REF:0000107
(PMID:15100151)		 RGD
Ensembl		 PMID:15100151 PMID:15128762 GO_REF:0000107 NCBI chr 9:20,133,193...20,139,933
Ensembl chr 9:12,635,590...12,642,347 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 located_in ISO (PMID:22589474) RGD PMID:22589474 NCBI chr12:21,842,206...21,958,556
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated located_in ISO (PMID:16123220) RGD PMID:16123220 NCBI chr 1:143,633,167...143,656,228
Ensembl chr 1:134,223,949...134,246,970 		JBrowse link
platelet alpha granule membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Selp selectin P located_in ISO
IEA		 (PMID:15297306)
GO_REF:0000107		 RGD
Ensembl		 PMID:15297306 GO_REF:0000107 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Snca synuclein alpha located_in IEA
ISO		 GO_REF:0000107
(PMID:12239163)		 Ensembl
RGD		 PMID:12239163 GO_REF:0000107 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sparc secreted protein acidic and cysteine rich located_in ISO
IEA		 (PMID:1737102)
GO_REF:0000107		 RGD
Ensembl		 PMID:1737102 GO_REF:0000107 NCBI chr10:40,017,065...40,038,816
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21364
    cellular anatomical structure 21069
      endomembrane system 4414
        secretory granule 479
          platelet alpha granule 21
            platelet alpha granule lumen 0
            platelet alpha granule membrane 3
Path 2
Term Annotations click to browse term
  cellular_component 21364
    cellular anatomical structure 21069
      organelle 14290
        membrane-bounded organelle 12860
          vesicle 2266
            intracellular vesicle 2080
              cytoplasmic vesicle 2071
                secretory vesicle 746
                  secretory granule 479
                    platelet alpha granule 21
                      platelet alpha granule lumen 0
                      platelet alpha granule membrane 3
paths to the root