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ONTOLOGY REPORT - ANNOTATIONS

Term:thiamine pyrophosphate binding
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Accession:GO:0030976 term browser browse the term
Definition:Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
Synonyms:exact_synonym: TPP binding;   aneurine pyrophosphate binding;   cocarboxylase binding;   diphosphothiamin binding;   thiamin pyrophosphate binding


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thiamine pyrophosphate binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723 		JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 enables IDA
ISO
IEA
IBA		 PMID:10468558
(PMID:10468558), (PMID:21708296)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033		 RGD
InterPro
Ensembl
GO_Central		 PMID:10468558 PMID:21708296 PMID:10468558 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:708588 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027 		JBrowse link
G Ilvbl ilvB acetolactate synthase like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924 		JBrowse link
G Ogdh oxoglutarate dehydrogenase enables ISO
ISS
IEA		 (PMID:24495017)
GO_REF:0000024
GO_REF:0000002
GO_REF:0000107		 RGD
UniProt
InterPro
Ensembl		 PMID:24495017 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Ogdhl oxoglutarate dehydrogenase L enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:7,578,343...7,604,385
Ensembl chr16:7,578,367...7,604,386 		JBrowse link
G Tkt transketolase enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16116031 GO_REF:0000033, RGD:1580394 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
G Tktl1 transketolase-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:151,954,261...151,987,208
Ensembl chr  X:151,954,175...151,987,208 		JBrowse link
G Tktl2 transketolase-like 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:23,202,460...23,209,741
Ensembl chr16:23,202,453...23,209,742 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    binding 17722
      sulfur compound binding 278
        thiamine pyrophosphate binding 8
Path 2
Term Annotations click to browse term
  molecular_function 20634
    binding 17722
      small molecule binding 6195
        ion binding 5913
          cation binding 4088
            thiamine pyrophosphate binding 8
paths to the root