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ONTOLOGY REPORT - ANNOTATIONS

Term:Smc5-Smc6 complex
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Accession:GO:0030915 term browser browse the term
Definition:A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.


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Smc5-Smc6 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eid3 EP300 interacting inhibitor of differentiation 3 part_of ISO
ISS
IBA		 (PMID:18086888)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:18086888 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:20,860,073...20,861,395 JBrowse link
G Nsmce1 NSE1 homolog, SMC5-SMC6 complex component part_of ISO
ISS
IEA
IBA		 (PMID:18086888)
GO_REF:0000024
GO_REF:0000104
GO_REF:0000033
(PMID:26919979)		 RGD
UniProt
GO_Central		 PMID:18086888 PMID:26919979 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:180,030,355...180,058,541
Ensembl chr 1:180,030,160...180,058,417 		JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase part_of ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:18086888)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
InterPro
Ensembl
GO_Central		 PMID:18086888 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899 		JBrowse link
G Nsmce3 NSE3 homolog, SMC5-SMC6 complex component part_of ISO (PMID:18086888), (PMID:27427983) RGD PMID:18086888 PMID:27427983 NCBI chr 1:118,401,302...118,402,629 JBrowse link
G Nsmce4a NSE4 homolog A, SMC5-SMC6 complex component part_of ISO
IBA		 (PMID:18086888)
GO_REF:0000033		 RGD
GO_Central		 PMID:18086888 GO_REF:0000033 NCBI chr 1:185,102,075...185,109,166
Ensembl chr 1:185,094,360...185,109,166 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 part_of ISO
IBA		 (PMID:18086888)
GO_REF:0000033
(PMID:26919979)		 RGD
GO_Central		 PMID:18086888 PMID:26919979 GO_REF:0000033 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 part_of ISO
IBA		 (PMID:18086888)
GO_REF:0000033
(PMID:26919979)		 RGD
GO_Central		 PMID:18086888 PMID:26919979 GO_REF:0000033 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21321
    protein-containing complex 6790
      catalytic complex 1935
        transferase complex 977
          SUMO ligase complex 13
            Smc5-Smc6 complex 7
Path 2
Term Annotations click to browse term
  cellular_component 21321
    cellular anatomical structure 21026
      organelle 14240
        membraneless organelle 5379
          intracellular membraneless organelle 5379
            chromosome 1403
              condensed chromosome 274
                Smc5-Smc6 complex 7
paths to the root