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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of blood coagulation
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Accession:GO:0030193 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of blood coagulation.



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regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H acts_upstream_of_or_within ISO MGI:2157224 (PMID:11145969) RGD PMID:11145969 NCBI chr10:93,342,435...93,356,334 JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:17848177)
GO_REF:0000107
RGD
Ensembl
PMID:17848177 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616 JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO (PMID:30213874) RGD PMID:30213874 NCBI chr 5:154,179,065...154,360,459 JBrowse link
G F11 coagulation factor XI acts_upstream_of_or_within ISO MGI:2384015 (PMID:16533887) RGD PMID:16533887 NCBI chr16:46,987,988...47,009,015 JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO (PMID:17848177) RGD PMID:17848177 NCBI chr 2:26,869,343...26,885,856 JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:17848177) RGD PMID:17848177 NCBI chr 2:28,507,003...28,519,954 JBrowse link
G Foxa2 forkhead box A2 involved_in ISO
IEA
(PMID:12911579)
GO_REF:0000107
RGD
Ensembl
PMID:12911579 GO_REF:0000107 NCBI chr 3:135,470,123...135,474,326 JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISO
ISS
(PMID:21304106), (PMID:6740558)
(PMID:15869579)
GO_REF:0000024
RGD
UniProt
PMID:6740558 PMID:15869579 PMID:21304106 GO_REF:0000024 NCBI chr11:78,054,488...78,069,402 JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:78,039,371...78,049,353 JBrowse link
G Serpinc1 serpin family C member 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:75,790,558...75,804,826 JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 IMP RGD PMID:14765194 RGD:1303972 NCBI chr 1:191,932,969...191,935,490 JBrowse link
activation of blood coagulation via clotting cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 involved_in ISO (PMID:21107324) RGD PMID:21107324 NCBI chr 7:126,933,919...127,113,588 JBrowse link
G Vwf von Willebrand factor acts_upstream_of_or_within ISO (PMID:30573509) RGD PMID:30573509 NCBI chr 4:160,042,900...160,177,757 JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3028929 (PMID:14702107)
Ensembl
RGD
PMID:14702107 GO_REF:0000107 NCBI chr 8:78,986,252...79,022,638 JBrowse link
G Cpb2 carboxypeptidase B2 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:11848438 GO_REF:0000033, RGD:632532 NCBI chr15:50,557,722...50,606,569 JBrowse link
G F12 coagulation factor XII involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,212,819...9,220,664 JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO
IEA
(PMID:12855810)
GO_REF:0000107
RGD
Ensembl
PMID:12855810 GO_REF:0000107 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA
(PMID:16846481)
GO_REF:0000033
RGD
GO_Central
PMID:16846481 GO_REF:0000033 NCBI chr 2:170,672,169...170,679,572 JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,394,901...168,402,863 JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,354,880...168,362,325 JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) RGD PMID:12855810 NCBI chr10:55,352,938...55,355,804 JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000043
MGI:3789962 (PMID:15869579)
UniProt
RGD
PMID:15869579 GO_REF:0000043 NCBI chr11:78,054,488...78,069,402 JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:78,039,371...78,049,353 JBrowse link
G Klkb1 kallikrein B1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:46,958,634...46,982,054 JBrowse link
G Plau plasminogen activator, urokinase involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
(PMID:9733098)
GO_Central
Ensembl
RGD
PMID:9733098 GO_REF:0000033 GO_REF:0000107 NCBI chr15:3,505,485...3,511,987 JBrowse link
G Plg plasminogen involved_in ISO
IEA
(PMID:14688145), (PMID:17307854), (PMID:22025510)
GO_REF:0000104
RGD
UniProt
PMID:14688145 PMID:17307854 PMID:22025510 GO_REF:0000104 NCBI chr 1:48,325,186...48,367,643 JBrowse link
G Pros1 protein S involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:13,676,310...13,757,858 JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:90,249,410...90,259,299 JBrowse link
negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen-dependent TFPI-regulating protein involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr17:22,907,758...22,993,834 JBrowse link
G Anxa5 annexin A5 IDA RGD PMID:20684318 RGD:7241850 NCBI chr 2:121,242,133...121,272,935 JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:8995232) RGD PMID:8995232 NCBI chr 1:88,481,889...88,485,816 JBrowse link
G Apoh apolipoprotein H involved_in ISO
IEA
(PMID:4052628)
GO_REF:0000107
RGD
Ensembl
PMID:4052628 GO_REF:0000107 NCBI chr10:93,342,435...93,356,334 JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO (PMID:10761923) RGD PMID:10761923 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G Kng1 kininogen 1 involved_in ISO
IBA
(PMID:11970955)
GO_REF:0000033
RGD
GO_Central
PMID:11970955 GO_REF:0000033 NCBI chr11:77,812,757...77,835,555 JBrowse link
G Kng2 kininogen 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:77,913,876...77,936,247 JBrowse link
G Kng2l1 kininogen 2-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:77,978,795...78,002,976 JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:9395524) RGD PMID:9395524 NCBI chr14:17,582,477...17,583,392 JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:2183063 (PMID:9616155), (PMID:9788960)
GO_REF:0000033
RGD
GO_Central
PMID:9616155 PMID:9788960 PMID:1440533 GO_REF:0000033, RGD:11100042 NCBI chr18:24,038,596...24,049,061 JBrowse link
G Serpine2 serpin family E member 2 involved_in IDA
ISO
PMID:17379830
(PMID:17379830)
RGD PMID:17379830 PMID:17379830 RGD:8553298 NCBI chr 9:81,124,746...81,188,866 JBrowse link
G Tfpi tissue factor pathway inhibitor involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr 3:89,939,862...89,989,253 JBrowse link
G Thbd thrombomodulin involved_in ISO (PMID:10761923) RGD PMID:10761923 NCBI chr 3:156,316,526...156,320,178 JBrowse link
G Tspan8 tetraspanin 8 IDA RGD PMID:9531564 RGD:634231 NCBI chr 7:51,444,946...51,479,360 JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO
IEA
(PMID:14726399)
GO_REF:0000107
RGD
Ensembl
PMID:14726399 GO_REF:0000107 NCBI chr10:93,342,435...93,356,334 JBrowse link
G Cpb2 carboxypeptidase B2 IDA RGD PMID:17002650 RGD:2313647 NCBI chr15:50,557,722...50,606,569 JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3789962 (PMID:15869579)
GO_Central
RGD
PMID:15869579 GO_REF:0000033 NCBI chr11:78,054,488...78,069,402 JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:78,039,371...78,049,353 JBrowse link
G Plg plasminogen involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr 1:48,325,186...48,367,643 JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA
(PMID:2503541)
GO_REF:0000107
RGD
Ensembl
PMID:2503541 GO_REF:0000107 NCBI chr12:25,237,977...25,248,356 JBrowse link
G Serpinf2 serpin family F member 2 involved_in IMP
ISO
(PMID:134998) RGD PMID:134998 PMID:6506034 RGD:1625541 NCBI chr10:60,272,400...60,280,506 JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:125,510,250...125,525,402 JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
(PMID:8995232)
Ensembl
RGD
PMID:8995232 GO_REF:0000107 NCBI chr 1:88,481,889...88,485,816 JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:103,660,319...103,681,662 JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of_or_within ISO MGI:2652408 (PMID:10557321), (PMID:11435305) RGD PMID:10557321 PMID:11435305 NCBI chr11:70,443,613...70,446,705 JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
IEA
ISS
(PMID:2538439)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056 JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA
(PMID:2538439)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,419,882...113,438,343 JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:8188664)
UniProt
Ensembl
RGD
PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,360,027...33,408,604 JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within
involved_in
ISO MGI:2387774 (PMID:19855083) RGD PMID:19855083 NCBI chr 9:81,124,746...81,188,866 JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 acts_upstream_of_or_within ISO (PMID:19218546) RGD PMID:19218546 NCBI chr19:41,686,951...41,840,035 JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO
GO_REF:0000024
(PMID:9501222)
UniProt
RGD
PMID:9501222 GO_REF:0000024 NCBI chr10:54,958,263...54,970,542 JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:16195328)
Ensembl
RGD
PMID:16195328 GO_REF:0000107 NCBI chr10:103,660,319...103,681,662 JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:18541721)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18541721 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:158,256,328...158,289,136 JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19008452)
UniProt
RGD
PMID:19008452 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810 JBrowse link
G Prkcd protein kinase C, delta involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16940418)
UniProt
Ensembl
RGD
PMID:16940418 GO_REF:0000024 GO_REF:0000107 NCBI chr16:5,775,681...5,806,122 JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:237,818,950...239,052,184 JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19855083)
Ensembl
RGD
PMID:19855083 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866 JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO
IEA
UniProtKB:P35951 (PMID:27430239)
GO_REF:0000107
RGD
Ensembl
PMID:27430239 GO_REF:0000107 NCBI chr12:34,731,934...34,753,617 JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 involved_in ISO (PMID:30425049) RGD PMID:30425049 NCBI chr 6:88,960,691...88,971,744 JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (PMID:20585042) RGD PMID:20585042 NCBI chr 8:41,385,419...41,532,248 JBrowse link
phosphatidylserine exposure on blood platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 involved_in ISO (PMID:21107324) RGD PMID:21107324 NCBI chr 7:126,933,919...127,113,588 JBrowse link
positive regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in IEA
ISO
GO_REF:0000107
(PMID:20978343)
Ensembl
RGD
PMID:20978343 GO_REF:0000107 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Emilin2 elastin microfibril interfacer 2 involved_in ISO (PMID:25658937) RGD PMID:25658937 NCBI chr 9:111,160,708...111,220,463 JBrowse link
G Enpp4 ectonucleotide pyrophosphatase/phosphodiesterase 4 involved_in ISO (PMID:22995898) RGD PMID:22995898 NCBI chr 9:16,888,923...16,898,860 JBrowse link
G F12 coagulation factor XII involved_in IEA
ISO
GO_REF:0000107
(PMID:6793628)
Ensembl
RGD
PMID:6793628 GO_REF:0000107 NCBI chr17:9,212,819...9,220,664 JBrowse link
G F2 coagulation factor II, thrombin involved_in IMP
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000107
(PMID:9038223)
GO_Central
Ensembl
RGD
PMID:9038223 PMID:20664909 GO_REF:0000033 GO_REF:0000107, RGD:10449431 NCBI chr 3:98,051,958...98,065,246 JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
ISS
GO_REF:0000107
MGI:3038377 (PMID:18305483)
GO_REF:0000033
GO_REF:0000024
(PMID:9038223)
Ensembl
RGD
GO_Central
UniProt
PMID:9038223 PMID:18305483 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856 JBrowse link
G F7 coagulation factor VII IDA RGD PMID:12757778 RGD:2312295 NCBI chr16:83,191,896...83,202,775 JBrowse link
G Hpse heparanase involved_in IEA
ISO
GO_REF:0000107
(PMID:20634491)
Ensembl
RGD
PMID:20634491 GO_REF:0000107 NCBI chr14:9,200,971...9,241,377 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (PMID:20978343) RGD PMID:20978343 NCBI chr 3:81,001,529...81,031,165 JBrowse link
G Prdx2 peroxiredoxin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:20978343)
Ensembl
RGD
PMID:20978343 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217 JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in ISO (PMID:24691441) RGD PMID:24691441 NCBI chr 2:178,487,941...178,490,622 JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO (PMID:9207454) RGD PMID:9207454 NCBI chr12:25,237,977...25,248,356 JBrowse link
G St3gal4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:12097641)
UniProt
RGD
PMID:12097641 GO_REF:0000024 NCBI chr 8:33,415,666...33,465,319 JBrowse link
G Tbxa2r thromboxane A2 receptor IMP RGD PMID:7848332 RGD:11059887 NCBI chr 7:9,034,077...9,041,489 JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:3997886) RGD PMID:3997886 NCBI chr 3:125,510,250...125,525,402 JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:46,987,988...47,009,015 JBrowse link
G F12 coagulation factor XII involved_in IEA
ISO
GO_REF:0000107
(PMID:89876)
Ensembl
RGD
PMID:89876 GO_REF:0000107 NCBI chr17:9,212,819...9,220,664 JBrowse link
G Klkb1 kallikrein B1 involved_in ISO
IEA
(PMID:89876)
GO_REF:0000107
RGD
Ensembl
PMID:89876 GO_REF:0000107 NCBI chr16:46,958,634...46,982,054 JBrowse link
G Plg plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) RGD PMID:6438154 PMID:26667841 NCBI chr 1:48,325,186...48,367,643 JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 TAS RGD PMID:11739291 RGD:1578383 NCBI chr 8:78,986,252...79,022,638 JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:16480936) RGD PMID:16480936 NCBI chr10:93,342,435...93,356,334 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    regulation of biological process 13375
      regulation of hemostasis 67
        regulation of blood coagulation 65
          negative regulation of blood coagulation + 46
          positive regulation of blood coagulation + 23
          regulation of blood coagulation, common pathway + 0
          regulation of blood coagulation, extrinsic pathway + 0
          regulation of blood coagulation, intrinsic pathway + 0
          regulation of fibrinolysis + 12
Path 2
Term Annotations click to browse term
  biological_process 20534
    biological regulation 13821
      regulation of biological process 13375
        regulation of response to stimulus 4324
          regulation of response to stress 1470
            regulation of response to wounding 188
              regulation of wound healing 138
                regulation of blood coagulation 65
                  negative regulation of blood coagulation + 46
                  positive regulation of blood coagulation + 23
                  regulation of blood coagulation, common pathway + 0
                  regulation of blood coagulation, extrinsic pathway + 0
                  regulation of blood coagulation, intrinsic pathway + 0
                  regulation of fibrinolysis + 12
paths to the root