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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of Wnt signaling pathway
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Accession:GO:0030177 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
Synonyms:exact_synonym: positive regulation of Wnt receptor signaling pathway;   positive regulation of Wnt receptor signalling pathway;   positive regulation of Wnt-activated signaling pathway;   positive regulation of frizzled signaling pathway;   positive regulation of frizzled signalling pathway;   up regulation of Wnt receptor signaling pathway;   up regulation of frizzled signaling pathway;   upregulation of Wnt receptor signaling pathway;   upregulation of frizzled signaling pathway
 narrow_synonym: activation of Wnt receptor signaling pathway;   activation of frizzled signaling pathway;   stimulation of Wnt receptor signaling pathway;   stimulation of frizzled signaling pathway
 alt_id: GO:0045811


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positive regulation of Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067 		JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,519,869...38,525,217
Ensembl chr 6:38,520,765...38,525,062 		JBrowse link
G ATP6V1C2 ATPase H+ transporting V1 subunit C2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,602,348...7,653,402
Ensembl chr17:7,599,535...7,653,402 		JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 IEA
ISO		 (PMID:19213727) Ensembl
MGI		 PMID:19213727 GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G CCN4 cellular communication network factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,648,720...29,683,822
Ensembl chr13:29,648,639...29,679,732 		JBrowse link
G CDC73 cell division cycle 73 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:5,826,209...5,937,930
Ensembl chr38:5,805,916...5,938,111 		JBrowse link
G CRBN cereblon involved_in ISO (PMID:34489457) FlyBase PMID:34489457 NCBI chr20:14,240,723...14,275,617
Ensembl chr20:14,240,804...14,274,940 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in ISO (PMID:17027228) ParkinsonsUK-UCL PMID:17027228 NCBI chr 9:83,395...110,309
Ensembl chr 9:73,215...110,269 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in ISO (PMID:17027228) ParkinsonsUK-UCL PMID:17027228 NCBI chr10:26,386,646...26,412,429
Ensembl chr10:26,393,033...26,411,624 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:12700239) UniProt PMID:12700239 NCBI chr24:20,333,593...20,390,341 JBrowse link
G DACT1 dishevelled binding antagonist of beta catenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:33,950,016...33,959,671
Ensembl chr 8:33,949,926...33,958,449 		JBrowse link
G DEPDC1B DEP domain containing 1B involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:47,295,970...47,369,234
Ensembl chr 2:47,296,656...47,482,064 		JBrowse link
G DISC1 DISC1 scaffold protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:7,524,336...7,825,143
Ensembl chr 4:7,524,397...7,822,558 		JBrowse link
G DIXDC1 DIX domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,097,000...21,168,470
Ensembl chr 5:21,100,045...21,167,166 		JBrowse link
G FGF10 fibroblast growth factor 10 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:16989802) UniProt
MGI		 PMID:16989802 GO_REF:0000024 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621 		JBrowse link
G FZD4 frizzled class receptor 4 involved_in ISO (PMID:11401527) BHF-UCL PMID:11401527 NCBI chr21:12,699,886...12,709,132
Ensembl chr21:12,699,774...12,724,923 		JBrowse link
G HHEX hematopoietically expressed homeobox involved_in ISO (PMID:16936074) UniProt PMID:16936074 NCBI chr28:7,057,379...7,063,326
Ensembl chr28:7,057,283...7,063,330 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:42,456,793...42,474,122
Ensembl chr15:42,456,764...42,579,311 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:89,446,340...89,618,716
Ensembl chr 1:89,480,399...89,618,143 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019 		JBrowse link
G LGR6 leucine rich repeat containing G protein-coupled receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:731,934...837,092
Ensembl chr 7:731,931...834,893 		JBrowse link
G MACF1 microtubule actin crosslinking factor 1 involved_in ISO (PMID:16815997) UniProt PMID:16815997 NCBI chr15:3,361,887...3,703,891
Ensembl chr15:3,362,867...3,573,325 		JBrowse link
G MBD2 methyl-CpG binding domain protein 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:21,232,260...21,283,687
Ensembl chr 1:21,235,967...21,283,346 		JBrowse link
G MESD mesoderm development LRP chaperone involved_in ISO (PMID:12581525) UniProt PMID:12581525 NCBI chr 3:56,698,417...56,709,632
Ensembl chr 3:56,705,479...56,709,536 		JBrowse link
G PBXIP1 PBX homeobox interacting protein 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:42,514,306...42,524,056
Ensembl chr 7:42,514,423...42,523,585 		JBrowse link
G RSPO1 R-spondin 1 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr15:4,857,887...4,876,077
Ensembl chr15:4,856,853...4,876,800 		JBrowse link
G RSPO2 R-spondin 2 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr13:8,610,227...8,755,727
Ensembl chr13:8,611,952...8,754,859 		JBrowse link
G RSPO3 R-spondin 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:65,858,822...65,936,160
Ensembl chr 1:65,858,794...65,936,322 		JBrowse link
G RSPO4 R-spondin 4 involved_in IEA UniProt
Ensembl		 GO_REF:0000107 GO_REF:0000117 NCBI chr24:19,952,113...19,987,498
Ensembl chr24:19,952,043...19,989,013 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,242,742...64,260,021
Ensembl chr 2:64,243,987...64,259,521 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,175,489...50,268,865
Ensembl chr20:50,175,687...50,268,836 		JBrowse link
G SPIN1 spindlin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:97,353,108...97,426,563
Ensembl chr 1:97,356,125...97,390,646 		JBrowse link
G SULF1 sulfatase 1 involved_in IEA
IBA
ISS		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr29:18,709,406...18,885,248
Ensembl chr29:18,709,445...18,884,378 		JBrowse link
G SULF2 sulfatase 2 involved_in IEA
IBA		 UniProt
GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr24:34,732,000...34,850,347
Ensembl chr24:34,732,037...34,828,569 		JBrowse link
G TERT telomerase reverse transcriptase involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107
G TMEM132A transmembrane protein 132A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:55,363,713...55,376,227
Ensembl chr18:55,363,698...55,385,587 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:30,247,432...30,262,992
Ensembl chr 1:30,251,059...30,261,001 		JBrowse link
G WLS Wnt ligand secretion mediator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:77,053,242...77,146,549
Ensembl chr 6:77,053,237...77,317,761 		JBrowse link
G WNT3 Wnt family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:10,073,019...10,124,454
Ensembl chr 9:10,077,567...10,124,508 		JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:46,419,812...46,541,888
Ensembl chr19:46,423,998...46,542,122 		JBrowse link
G ZRANB1 zinc finger RANBP2-type containing 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr28:34,220,596...34,259,642
Ensembl chr28:34,220,596...34,256,620 		JBrowse link
positive regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRA2 adhesion G protein-coupled receptor A2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr16:27,547,722...27,583,069
Ensembl chr16:27,549,308...27,583,070 		JBrowse link
G ADNP activity dependent neuroprotector homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:37,211,776...37,245,938
Ensembl chr24:37,213,942...37,243,702 		JBrowse link
G AMER1 APC membrane recruitment protein 1 involved_in ISO (PMID:21304492) UniProt PMID:21304492 NCBI chr  X:49,426,228...49,449,448 JBrowse link
G ARNTL aryl hydrocarbon receptor nuclear translocator like involved_in ISO (PMID:22611086), (PMID:23525013) UniProt PMID:22611086 PMID:23525013 NCBI chr21:36,254,235...36,323,915
Ensembl chr21:36,290,070...36,323,622 		JBrowse link
G ASPM assembly factor for spindle microtubules acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:5,591,530...5,663,673
Ensembl chr 7:5,590,957...5,660,919 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067 		JBrowse link
G B9D2 B9 domain containing 2 involved_in
acts_upstream_of		 ISO (PMID:12893825), (PMID:15040835)
(PMID:25605017)		 CACAO
ARUK-UCL		 PMID:12893825 PMID:15040835 PMID:25605017 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:17,453,628...17,459,812
Ensembl chr 2:17,455,243...17,462,346 		JBrowse link
G CAPRIN2 caprin family member 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr27:17,518,966...17,560,866
Ensembl chr27:17,517,155...17,560,511 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:34,660,026...34,674,129
Ensembl chr25:34,660,553...34,674,037 		JBrowse link
G CDH3 cadherin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:80,864,859...80,912,136
Ensembl chr 5:80,863,661...80,913,019 		JBrowse link
G COL1A1 collagen type I alpha 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:83,395...110,309
Ensembl chr 9:73,215...110,269 		JBrowse link
G CSNK1E casein kinase 1 epsilon acts_upstream_of_or_within ISO (PMID:14966280)
(PMID:17606995)		 MGI PMID:14966280 PMID:17606995 NCBI chr10:26,386,646...26,412,429
Ensembl chr10:26,393,033...26,411,624 		JBrowse link
G CSNK1G1 casein kinase 1 gamma 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr30:28,661,726...28,832,193
Ensembl chr30:28,654,200...28,788,801 		JBrowse link
G CSNK1G2 casein kinase 1 gamma 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:57,015,019...57,042,269
Ensembl chr20:57,015,614...57,040,694 		JBrowse link
G CSNK1G3 casein kinase 1 gamma 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:13,357,816...13,465,708
Ensembl chr11:13,357,894...13,464,138 		JBrowse link
G CTDNEP1 CTD nuclear envelope phosphatase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:32,211,185...32,216,921
Ensembl chr 5:32,211,343...32,216,698 		JBrowse link
G DAAM2 dishevelled associated activator of morphogenesis 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:8,686,653...8,801,903
Ensembl chr12:8,748,655...8,799,059 		JBrowse link
G DACT1 dishevelled binding antagonist of beta catenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:33,950,016...33,959,671
Ensembl chr 8:33,949,926...33,958,449 		JBrowse link
G DAPK3 death associated protein kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,590,199...55,603,883
Ensembl chr20:55,590,223...55,602,682 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:35,759,367...35,789,759
Ensembl chr  X:35,759,416...35,789,774 		JBrowse link
G DKK2 dickkopf WNT signaling pathway inhibitor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:27,548,877...27,647,039
Ensembl chr32:27,550,833...27,713,838 		JBrowse link
G DLX5 distal-less homeobox 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:22,080,351...22,085,188
Ensembl chr14:22,080,699...22,084,867 		JBrowse link
G EDA ectodysplasin A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:54,078,694...54,515,535
Ensembl chr  X:54,078,966...54,515,535 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:30,073,541...30,166,904
Ensembl chr32:30,073,950...30,166,295 		JBrowse link
G EGFR epidermal growth factor receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631 		JBrowse link
G FAM53B family with sequence similarity 53 member B involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr28:33,961,810...34,077,075
Ensembl chr28:33,933,605...34,081,090 		JBrowse link
G FGF10 fibroblast growth factor 10 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:16858399) MGI PMID:16858399 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G FGF9 fibroblast growth factor 9 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr25:16,630,321...16,665,935
Ensembl chr25:16,632,812...16,663,550 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:16720875)
(PMID:18533146)		 UniProt
MGI		 PMID:16720875 PMID:18533146 GO_REF:0000024 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:19407216) MGI PMID:19407216 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896 		JBrowse link
G FRAT1 frequently rearranged in advanced T-cell lymphomas involved_in ISO (PMID:12556519) WB PMID:12556519 NCBI chr28:10,635,959...10,637,321
Ensembl chr28:10,635,944...10,636,787 		JBrowse link
G FRAT1 FRAT regulator of WNT signaling pathway 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107
G FZD9 frizzled class receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,782,394...6,784,565
Ensembl chr 6:6,782,774...6,784,558 		JBrowse link
G GID8 GID complex subunit 8 homolog involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr24:46,741,165...46,751,516
Ensembl chr24:46,741,140...46,746,352 		JBrowse link
G GLIPR2 GLI pathogenesis related 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,622,460...52,634,602
Ensembl chr11:52,615,039...52,681,270 		JBrowse link
G GPC3 glypican 3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:104,313,426...104,751,215
Ensembl chr  X:104,313,591...104,751,756 		JBrowse link
G GPC5 glypican 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr22:42,526,426...43,873,992
Ensembl chr22:42,526,054...43,870,405 		JBrowse link
G GPRC5B G protein-coupled receptor class C group 5 member B involved_in ISO (PMID:24089469) UniProt PMID:24089469 NCBI chr 6:25,412,968...25,435,895
Ensembl chr 6:25,411,595...25,432,824 		JBrowse link
G GSKIP GSK3B interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:65,110,659...65,131,205
Ensembl chr 8:65,111,414...65,129,622 		JBrowse link
G HHEX hematopoietically expressed homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:7,057,379...7,063,326
Ensembl chr28:7,057,283...7,063,330 		JBrowse link
G ILK integrin linked kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,911,326...29,917,972
Ensembl chr21:29,911,364...29,917,974 		JBrowse link
G JRK Jrk helix-turn-helix protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:36,754,771...36,767,799 JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:89,446,340...89,618,716
Ensembl chr 1:89,480,399...89,618,143 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr21:47,952,019...47,995,530
Ensembl chr21:47,952,890...47,996,288 		JBrowse link
G LGR5 leucine rich repeat containing G protein-coupled receptor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:13,009,028...13,136,685
Ensembl chr10:13,007,843...13,136,998 		JBrowse link
G LRRK1 leucine rich repeat kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,003,299...40,122,326
Ensembl chr 3:40,004,557...40,122,320 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G LYPD6 LY6/PLAUR domain containing 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:51,007,147...51,069,110
Ensembl chr19:51,041,219...51,067,333 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:20128690 RGD:150573713 NCBI chr 2:43,918,210...43,996,817
Ensembl chr 2:43,917,604...43,995,209 		JBrowse link
G MIR183 microRNA mir-183 involved_in ISO (PMID:23538390) BHF-UCL PMID:23538390 NCBI chr14:7,068,542...7,068,603
Ensembl chr14:7,068,519...7,068,625 		JBrowse link
G MIR26A-1 microRNA mir-26a-1 involved_in ISO (PMID:22484120) ARUK-UCL PMID:22484120 NCBI chr23:7,747,073...7,747,133
Ensembl chr23:7,747,064...7,747,140 		JBrowse link
G MIR26A-2 microRNA mir-26a-2 involved_in ISO (PMID:22484120) ARUK-UCL PMID:22484120 NCBI chr10:1,880,513...1,880,572
Ensembl chr10:1,880,513...1,880,572 		JBrowse link
G MIR346 microRNA mir-346 involved_in ISO (PMID:24023731) ARUK-UCL PMID:24023731 NCBI chr 4:34,073,335...34,073,429
Ensembl chr 4:34,073,335...34,073,429 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703 		JBrowse link
G NLE1 notchless homolog 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:38,222,083...38,230,819
Ensembl chr 9:38,222,051...38,365,621 		JBrowse link
G NRARP NOTCH regulated ankyrin repeat protein involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:48,394,568...48,396,849
Ensembl chr 9:48,394,754...48,395,098 		JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:51,156,887...51,168,131
Ensembl chr20:51,157,121...51,168,136 		JBrowse link
G PLEKHA4 pleckstrin homology domain containing A4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:107,491,617...107,517,993
Ensembl chr 1:107,492,587...107,517,800 		JBrowse link
G POU5F1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:35,336,055...35,384,249
Ensembl chr 8:35,336,140...35,377,551 		JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:46,590,110...46,680,792
Ensembl chr10:46,590,079...46,665,866 		JBrowse link
G PPM1N protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:110,067,163...110,071,274
Ensembl chr 1:110,068,499...110,070,422 		JBrowse link
G PPP2R3A protein phosphatase 2 regulatory subunit B''alpha involved_in ISO (PMID:16567647) BHF-UCL PMID:16567647 NCBI chr23:32,441,130...32,628,588
Ensembl chr23:32,471,921...32,626,548 		JBrowse link
G PRDM15 PR/SET domain 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:36,220,532...36,285,752
Ensembl chr31:36,223,507...36,286,699 		JBrowse link
G PTK7 protein tyrosine kinase 7 (inactive) involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:11,593,017...11,657,149
Ensembl chr12:11,593,043...11,656,320 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360 		JBrowse link
G RECK reversion inducing cysteine rich protein with kazal motifs involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,519,303...52,607,753
Ensembl chr11:52,519,317...52,607,217 		JBrowse link
G RNF146 ring finger protein 146 involved_in ISO (PMID:21478859) UniProt PMID:21478859 NCBI chr 1:65,988,600...66,010,873
Ensembl chr 1:65,988,656...66,010,881 		JBrowse link
G RNF220 ring finger protein 220 involved_in ISO (PMID:25266658) UniProt PMID:25266658 NCBI chr15:15,664,025...15,898,564
Ensembl chr15:15,664,876...15,891,748 		JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 involved_in ISO (PMID:18215320) BHF-UCL PMID:18215320 NCBI chr 1:95,209,122...95,280,956
Ensembl chr 1:95,088,745...95,280,151 		JBrowse link
G RPS12 ribosomal protein S12 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 1:25,836,409...25,839,148
Ensembl chr 1:25,836,500...25,839,146 		JBrowse link
G RSPO1 R-spondin 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:4,857,887...4,876,077
Ensembl chr15:4,856,853...4,876,800 		JBrowse link
G RSPO2 R-spondin 2 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:8,610,227...8,755,727
Ensembl chr13:8,611,952...8,754,859 		JBrowse link
G RSPO3 R-spondin 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:18842812)
(PMID:16543246)		 MGI
GO_Central		 PMID:16543246 PMID:18842812 GO_REF:0000033 NCBI chr 1:65,858,822...65,936,160
Ensembl chr 1:65,858,794...65,936,322 		JBrowse link
G RSPO4 R-spondin 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr24:19,952,113...19,987,498
Ensembl chr24:19,952,043...19,989,013 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:2,095,807...2,137,528
Ensembl chr20:2,095,786...2,137,579 		JBrowse link
G SBNO1 strawberry notch homolog 1 involved_in ISO (PMID:39343943) UniProt PMID:39343943 NCBI chr26:6,207,420...6,269,406
Ensembl chr26:6,216,435...6,263,098 		JBrowse link
G SCEL sciellin involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:30,874,267...31,171,598
Ensembl chr22:31,045,878...31,171,033 		JBrowse link
G SEMA5A semaphorin 5A involved_in ISO (PMID:19850054) UniProt PMID:19850054 NCBI chr34:4,612,202...5,089,071
Ensembl chr34:4,612,142...5,082,280 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18166153) MGI
Ensembl		 PMID:18166153 GO_REF:0000107 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
G SFRP4 secreted frizzled related protein 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:12,018,049...12,028,123
Ensembl chr18:12,017,978...12,027,788 		JBrowse link
G SMAD3 SMAD family member 3 involved_in ISO PMID:20097766 BHF-UCL PMID:20097766 RGD:11079190 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:20,098,783...20,101,357
Ensembl chr35:20,099,773...20,101,154 		JBrowse link
G SPIN4 spindlin family member 4 involved_in ISO (PMID:36927955) UniProt PMID:36927955 NCBI chr  X:48,805,292...48,809,546
Ensembl chr  X:48,808,215...48,808,964 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G SULF2 sulfatase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr24:34,732,000...34,850,347
Ensembl chr24:34,732,037...34,828,569 		JBrowse link
G TBL1X transducin beta like 1 X-linked involved_in ISO (PMID:18193033) UniProt PMID:18193033 NCBI chr  X:6,222,794...6,432,561 JBrowse link
G TBL1XR1 TBL1X/Y related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:40,573,631...40,690,975
Ensembl chr34:40,578,507...40,739,352 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G TMEM198 transmembrane protein 198 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr37:26,053,469...26,059,579
Ensembl chr37:26,052,168...26,058,810 		JBrowse link
G TMEM198B transmembrane protein 198B involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:214,159...219,028 JBrowse link
G TMEM9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chr 7:2,069,017...2,087,961 JBrowse link
G TNKS tankyrase involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:34,826,248...35,040,004
Ensembl chr16:34,831,662...35,039,946 		JBrowse link
G TNKS2 tankyrase 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr28:6,286,125...6,354,284
Ensembl chr28:6,285,690...6,352,317 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,261,760...107,304,157
Ensembl chr 1:107,261,756...107,303,346 		JBrowse link
G TTC21B tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO (PMID:27482817) MGI PMID:27482817 NCBI chr36:11,009,362...11,086,586
Ensembl chr36:11,010,296...11,086,674 		JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B involved_in ISO (PMID:18339854) UniProt PMID:18339854 NCBI chr11:22,523,671...22,541,473
Ensembl chr11:22,525,051...22,540,388 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:3,887,408...4,023,364
Ensembl chr13:3,879,220...4,023,955 		JBrowse link
G USP34 ubiquitin specific peptidase 34 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:61,264,605...61,459,603
Ensembl chr10:61,267,478...61,511,347 		JBrowse link
G USP47 ubiquitin specific peptidase 47 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:34,917,664...35,027,969
Ensembl chr21:34,911,269...35,026,790 		JBrowse link
G USP8 ubiquitin specific peptidase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:16,341,970...16,408,246
Ensembl chr30:16,342,009...16,408,012 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,636,986...51,651,749
Ensembl chr11:51,637,411...51,651,714 		JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (PMID:17239604) ParkinsonsUK-UCL PMID:17239604 NCBI chr15:8,428,073...8,454,601
Ensembl chr15:8,428,172...8,454,049 		JBrowse link
G WLS Wnt ligand secretion mediator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:77,053,242...77,146,549
Ensembl chr 6:77,053,237...77,317,761 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806 		JBrowse link
G WNK2 WNK lysine deficient protein kinase 2 involved_in ISO (PMID:23797875) FlyBase PMID:23797875 NCBI chr 1:98,433,897...98,533,427
Ensembl chr 1:98,454,799...98,493,085 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr27:5,599,905...5,605,506
Ensembl chr27:5,601,089...5,605,501 		JBrowse link
G WNT3A Wnt family member 3A acts_upstream_of_or_within
involved_in		 IEA Ensembl GO_REF:0000107 NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:29,394,760...29,495,977
Ensembl chr 5:29,394,541...29,496,251 		JBrowse link
G ZBED3 zinc finger BED-type containing 3 acts_upstream_of_or_within ISO (PMID:19141611) MGI PMID:19141611
G ZEB2 zinc finger E-box binding homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,419,812...46,541,888
Ensembl chr19:46,423,998...46,542,122 		JBrowse link
positive regulation of non-canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSNK1D casein kinase 1 delta involved_in ISO (PMID:17244647) ParkinsonsUK-UCL PMID:17244647 NCBI chr 9:83,395...110,309
Ensembl chr 9:73,215...110,269 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in ISO (PMID:17244647) ParkinsonsUK-UCL PMID:17244647 NCBI chr10:26,386,646...26,412,429
Ensembl chr10:26,393,033...26,411,624 		JBrowse link
G NKD1 NKD inhibitor of WNT signaling pathway 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,720,059...64,806,868
Ensembl chr 2:64,722,243...64,807,875 		JBrowse link
G RSPO1 R-spondin 1 acts_upstream_of_or_within ISO (PMID:21991325) MGI PMID:21991325 NCBI chr15:4,857,887...4,876,077
Ensembl chr15:4,856,853...4,876,800 		JBrowse link
G RSPO3 R-spondin 3 involved_in ISO (PMID:26766444) UniProt PMID:26766444 NCBI chr 1:65,858,822...65,936,160
Ensembl chr 1:65,858,794...65,936,322 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
positive regulation of Wnt signaling pathway, planar cell polarity pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20837657) MGI PMID:20837657 NCBI chr 7:20,696,659...20,735,362
Ensembl chr 7:20,700,144...20,727,410 		JBrowse link
G ANKRD6 ankyrin repeat domain 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:48,646,173...48,844,231
Ensembl chr12:48,646,173...48,842,451 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321 		JBrowse link
G GPC3 glypican 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:104,313,426...104,751,215
Ensembl chr  X:104,313,591...104,751,756 		JBrowse link
G MLLT3 MLLT3 super elongation complex subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:39,923,165...40,203,574
Ensembl chr11:39,927,517...40,203,281 		JBrowse link
G NKD1 NKD inhibitor of WNT signaling pathway 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,720,059...64,806,868
Ensembl chr 2:64,722,243...64,807,875 		JBrowse link
G PLEKHA4 pleckstrin homology domain containing A4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:107,491,617...107,517,993
Ensembl chr 1:107,492,587...107,517,800 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    cellular process 21672
      signal transduction 6398
        positive regulation of signal transduction 1764
          positive regulation of Wnt signaling pathway 153
            Wnt receptor recycling 0
            positive regulation of canonical Wnt signaling pathway 116
            positive regulation of non-canonical Wnt signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 22141
    biological regulation 12559
      regulation of biological process 12176
        regulation of cellular process 11829
          signal transduction 6398
            cell surface receptor signaling pathway 2822
              Wnt signaling pathway 467
                regulation of Wnt signaling pathway 346
                  positive regulation of Wnt signaling pathway 153
                    Wnt receptor recycling 0
                    positive regulation of canonical Wnt signaling pathway 116
                    positive regulation of non-canonical Wnt signaling pathway + 14
paths to the root