Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:platelet activation
go back to main search page
Accession:GO:0030168 term browser browse the term
Definition:A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
Synonyms:exact_synonym: blood coagulation, platelet activation
 xref: Reactome:R-HSA-392023 "Adrenaline signalling through Alpha-2 adrenergic receptor";   Reactome:R-HSA-392170 "ADP signalling through P2Y purinoceptor 12";   Reactome:R-HSA-418592 "ADP signalling through P2Y purinoceptor 1";   Reactome:R-HSA-76002 "Platelet activation, signaling and aggregation"


show annotations for term's descendants           Sort by:
platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 NOT|involved_in ISO (PMID:24069336) RGD PMID:24069336 NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:114,585,169...114,589,355 		JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846 		JBrowse link
G Axl Axl receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2387750 (PMID:15650770)		 GO_Central
RGD		 PMID:15650770 GO_REF:0000033 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 involved_in ISO (PMID:16385460) RGD PMID:16385460 NCBI chr 1:88,283,864...88,286,244
Ensembl chr 1:79,155,693...79,158,505 		JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 acts_upstream_of_or_within ISO MGI:4459539 (PMID:22988088) RGD PMID:22988088 NCBI chr  X:117,378,123...117,382,620
Ensembl chr  X:117,375,525...117,382,787 		JBrowse link
G Cd40lg CD40 ligand involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:9468137)
GO_REF:0000104		 UniProt
RGD		 PMID:9468137 GO_REF:0000024 GO_REF:0000104 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Ctsg cathepsin G involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:10702240)		 UniProt
Ensembl
RGD		 PMID:10702240 GO_REF:0000024 GO_REF:0000107 NCBI chr15:33,901,230...33,907,596
Ensembl chr15:29,931,003...29,937,353 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 acts_upstream_of_or_within ISO (PMID:11929769) RGD PMID:11929769 NCBI chr 1:249,374,810...249,502,310
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:11929769)		 Ensembl
RGD		 PMID:11929769 GO_REF:0000107 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G F2 coagulation factor II, thrombin involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:17380206)
GO_REF:0000033
(PMID:9038223)		 Ensembl
RGD
GO_Central		 PMID:9038223 PMID:17380206 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:9038223)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9038223 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 involved_in ISO (PMID:10702240) RGD PMID:10702240 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472 		JBrowse link
G Fga fibrinogen alpha chain involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO MGI:3050103 (PMID:19901330) RGD PMID:19901330 NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:70,055,068...70,086,776 		JBrowse link
G Gla galactosidase, alpha IMP RGD PMID:34320241 RGD:401976418 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Gna13 G protein subunit alpha 13 acts_upstream_of_or_within ISO MGI:2151775 (PMID:14528298) RGD PMID:14528298 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774 		JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of ISO MGI:2652408 (PMID:10557321), (PMID:11435305) RGD PMID:10557321 PMID:11435305 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
ISO		 GO_REF:0000024
(PMID:19903770)		 UniProt
RGD		 PMID:19903770 GO_REF:0000024 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO (PMID:15466936) RGD PMID:15466936 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:10828023)		 Ensembl
RGD		 PMID:10828023 GO_REF:0000107 NCBI chr20:5,138,553...5,204,189
Ensembl chr20:5,136,441...5,202,337 		JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase acts_upstream_of_or_within ISO MGI:2387765 (PMID:15650770) RGD PMID:15650770 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO MGI:2181608 (PMID:12913094) RGD PMID:12913094 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry12 purinergic receptor P2Y12 acts_upstream_of_or_within ISO MGI:2445936 (PMID:11413167) RGD PMID:11413167 NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Pf4 platelet factor 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11685038)		 UniProt
RGD		 PMID:11685038 GO_REF:0000024 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15834429)		 Ensembl
RGD		 PMID:15834429 GO_REF:0000107 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:24429998)		 UniProt
RGD		 PMID:24429998 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Rap2b RAP2B, member of RAS oncogene family involved_in ISO (PMID:18582561) RGD PMID:18582561 NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069 		JBrowse link
G Rasa3 RAS p21 protein activator 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:10828023)		 Ensembl
RGD		 PMID:10828023 GO_REF:0000107 NCBI chr16:75,855,360...75,969,349
Ensembl chr16:75,855,265...75,970,804 		JBrowse link
G Serpine2 serpin family E member 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2387774 (PMID:19855083)		 Ensembl
RGD		 PMID:19855083 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:3522206|MGI:3764698 (PMID:20525922) RGD PMID:20525922 NCBI chr 9:21,924,050...21,933,338
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Treml1 triggering receptor expressed on myeloid cells-like 1 involved_in ISO (PMID:15128762)
(PMID:15100151)		 RGD PMID:15100151 PMID:15128762 NCBI chr 9:20,133,193...20,139,933
Ensembl chr 9:12,635,590...12,642,347 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2387762 (PMID:15650770)		 UniProt
RGD		 PMID:15650770 GO_REF:0000024 NCBI chr 3:127,231,468...127,254,806
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO MGI:2670555 (PMID:27609517) RGD PMID:27609517 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
G Vwf von Willebrand factor involved_in
NOT|acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000104
MGI:2153009 (PMID:17380206)
MGI:2153009 (PMID:10930441), (PMID:21037087)
(PMID:8565074)		 UniProt
RGD		 PMID:8565074 PMID:10930441 PMID:17380206 PMID:21037087 GO_REF:0000104 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (PMID:19901330) RGD PMID:19901330 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:8995232)		 Ensembl
RGD		 PMID:8995232 GO_REF:0000107 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660 		JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of_or_within ISO MGI:2652408 (PMID:10557321), (PMID:11435305) RGD PMID:10557321 PMID:11435305 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
IEA
ISS		 (PMID:2538439)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA		 (PMID:2538439)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:8188664)		 UniProt
Ensembl
RGD		 PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within
involved_in		 ISO MGI:2387774 (PMID:19855083) RGD PMID:19855083 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 acts_upstream_of_or_within ISO (PMID:19218546) RGD PMID:19218546 NCBI chr19:41,686,951...41,840,035
Ensembl chr19:41,688,617...41,839,781 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO		 GO_REF:0000024
(PMID:9501222)		 UniProt
RGD		 PMID:9501222 GO_REF:0000024 NCBI chr10:55,456,923...55,469,239
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16195328)		 Ensembl
RGD		 PMID:16195328 GO_REF:0000107 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660 		JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18541721)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18541721 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19008452)		 UniProt
RGD		 PMID:19008452 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:16940418)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16940418 GO_REF:0000024 GO_REF:0000107 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19855083)		 Ensembl
RGD		 PMID:19855083 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO
IEA		 UniProtKB:P35951 (PMID:27430239)
GO_REF:0000107		 RGD
Ensembl		 PMID:27430239 GO_REF:0000107 NCBI chr12:40,391,755...40,414,336
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 involved_in ISO (PMID:30425049) RGD PMID:30425049 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (PMID:20585042) RGD PMID:20585042 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actg1 actin, gamma 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr10:106,118,106...106,120,951
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Actn1 actinin, alpha 1 NOT|involved_in ISO (PMID:23434115) RGD PMID:23434115 NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Bloc1s4 biogenesis of lysosomal organelles complex 1 subunit 4 acts_upstream_of_or_within ISO MGI:2449643 (PMID:11110696) RGD PMID:11110696 NCBI chr14:78,267,735...78,269,035
Ensembl chr14:74,043,015...74,044,531 		JBrowse link
G Cfh complement factor H acts_upstream_of_or_within ISO (PMID:28057640) RGD PMID:28057640 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Clic1 chloride intracellular channel 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,761,461...3,773,712 		JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180787 (PMID:26045608)		 Ensembl
RGD		 PMID:26045608 GO_REF:0000107 NCBI chr16:19,081,172...19,089,548
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr13:49,709,928...49,731,141
Ensembl chr13:47,167,789...47,179,384 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:8996251)
(PMID:8955160), (PMID:8996251)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:8955160 PMID:8996251 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:249,374,810...249,502,310
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:28032533)		 Ensembl
RGD		 PMID:28032533 GO_REF:0000107 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472 		JBrowse link
G Fermt3 FERM domain containing kindlin 3 involved_in IBA
ISO		 GO_REF:0000033
(PMID:18278053)		 GO_Central
RGD		 PMID:18278053 GO_REF:0000033 NCBI chr 1:213,618,691...213,636,889
Ensembl chr 1:204,189,484...204,207,587 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA		 (PMID:6281794)
GO_REF:0000033		 RGD
GO_Central		 PMID:6281794 GO_REF:0000033 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO
IBA		 (PMID:6281794)
GO_REF:0000033		 RGD
GO_Central		 PMID:6281794 GO_REF:0000033 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO
IBA		 (PMID:6281794)
GO_REF:0000033		 RGD
GO_Central		 PMID:6281794 GO_REF:0000033 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fibp FGF1 intracellular binding protein involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399 		JBrowse link
G Flna filamin A involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr  X:157,159,051...157,185,559
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO (PMID:15701726) RGD PMID:15701726 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gla galactosidase, alpha IMP RGD PMID:34320241 RGD:401976418 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Gnas GNAS complex locus involved_in ISO (PMID:12719376) RGD PMID:12719376 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gp6 glycoprotein VI acts_upstream_of_or_within IMP
ISO		 (PMID:28032533) RGD PMID:28032533 PMID:17322098 RGD:401824682 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:69,465,789...69,491,326 		JBrowse link
G Hbb hemoglobin subunit beta involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Ilk integrin-linked kinase involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:2175913 (PMID:28576878)
GO_REF:0000033
(PMID:15466936)		 Ensembl
RGD
GO_Central		 PMID:15466936 PMID:28576878 GO_REF:0000033 GO_REF:0000107 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Metap1 methionyl aminopeptidase 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434 		JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Myl12a myosin light chain 12A involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 9:110,891,970...110,899,655
Ensembl chr 9:110,873,959...110,916,580 		JBrowse link
G Myl9 myosin light chain 9 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in ISO
IEA		 (PMID:12578987)
GO_REF:0000107		 RGD
Ensembl		 PMID:12578987 GO_REF:0000107 NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8188664)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 acts_upstream_of_or_within ISO (PMID:28576878) RGD PMID:28576878 NCBI chr10:15,720,301...15,723,386
Ensembl chr10:15,215,824...15,220,931 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:28576878)		 Ensembl
RGD		 PMID:28576878 GO_REF:0000107 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 acts_upstream_of_or_within ISO MGI:5636896 (PMID:28576878) RGD PMID:28576878 NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:76,803,198...76,822,107 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Pear1 platelet endothelial aggregation receptor 1 involved_in ISO (PMID:27614188) RGD PMID:27614188 NCBI chr 2:173,206,298...173,234,106
Ensembl chr 2:173,207,664...173,227,440 		JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma acts_upstream_of_or_within ISO MGI:2385922|MGI:5496877 (PMID:23372168) RGD PMID:23372168 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988 		JBrowse link
G Plek pleckstrin involved_in IEA
ISO		 GO_REF:0000107
(PMID:19190246)		 Ensembl
RGD		 PMID:19190246 GO_REF:0000107 NCBI chr14:95,598,650...95,631,326
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:24429998)		 UniProt
RGD		 PMID:24429998 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3719625 (PMID:23509158)		 Ensembl
RGD		 PMID:23509158 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Rap2b RAP2B, member of RAS oncogene family involved_in ISO (PMID:18582561) RGD PMID:18582561 NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18317590)		 UniProt
RGD		 PMID:18317590 GO_REF:0000024 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (PMID:8699821) RGD PMID:8699821 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (PMID:12773094) RGD PMID:12773094 NCBI chr 3:36,474,428...36,536,120
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Stxbp3 syntaxin binding protein 3 involved_in ISO (PMID:12773094) RGD PMID:12773094 NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671 		JBrowse link
G Tln1 talin 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900 		JBrowse link
G Tspan32 tetraspanin 32 acts_upstream_of_or_within ISO MGI:2183564 (PMID:16720835) RGD PMID:16720835 NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445 		JBrowse link
G Tspan9 tetraspanin 9 acts_upstream_of_or_within ISO MGI:4027164 (PMID:28032533) RGD PMID:28032533 NCBI chr 4:160,813,879...160,995,574
Ensembl chr 4:160,813,879...160,995,501 		JBrowse link
G Tubb1 tubulin, beta 1 class VI involved_in ISO (PMID:30446499) RGD PMID:30446499 NCBI chr 3:183,666,189...183,675,656
Ensembl chr 3:163,247,967...163,256,063 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:20546121)
GO_REF:0000033
GO_REF:0000107		 UniProt
RGD
GO_Central
Ensembl		 PMID:20546121 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:127,231,468...127,254,806
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing, A NOT|acts_upstream_of_or_within ISO MGI:3051962 (PMID:27609517) RGD PMID:27609517 NCBI chr20:9,291,471...9,334,685
Ensembl chr20:9,292,139...9,329,224 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2670555 (PMID:27609517)		 GO_Central
RGD		 PMID:27609517 GO_REF:0000033 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
G Vcl vinculin involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr15:3,315,069...3,404,891
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (PMID:19901330) RGD PMID:19901330 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
positive regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:1939645) RGD PMID:1939645 NCBI chr10:55,831,901...55,856,729
Ensembl chr10:55,352,899...55,356,774 		JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta involved_in ISO (PMID:1939645) RGD PMID:1939645 NCBI chr11:95,882,561...95,883,738
Ensembl chr11:82,378,199...82,379,392 		JBrowse link
G Gp5 glycoprotein V (platelet) involved_in ISO
IEA		 (PMID:1939645)
GO_REF:0000107		 RGD
Ensembl		 PMID:1939645 GO_REF:0000107 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Gp9 glycoprotein IX (platelet) involved_in ISO (PMID:1939645) RGD PMID:1939645 NCBI chr 4:120,235,500...120,237,110
Ensembl chr 4:120,235,421...120,237,110 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Pdpn podoplanin IMP RGD PMID:16979138 RGD:2292241 NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Pear1 platelet endothelial aggregation receptor 1 involved_in ISO (PMID:36792666) RGD PMID:36792666 NCBI chr 2:173,206,298...173,234,106
Ensembl chr 2:173,207,664...173,227,440 		JBrowse link
G Pla2g4a phospholipase A2 group 4A involved_in ISO
IEA		 (PMID:18451993)
GO_REF:0000107		 RGD
Ensembl		 PMID:18451993 GO_REF:0000107 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Plek pleckstrin involved_in IEA
ISO		 GO_REF:0000107
(PMID:19190246)		 Ensembl
RGD		 PMID:19190246 GO_REF:0000107 NCBI chr14:95,598,650...95,631,326
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (PMID:19246339) RGD PMID:19246339 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Selp selectin P involved_in IEA
ISO		 GO_REF:0000107
(PMID:16514062)		 Ensembl
RGD		 PMID:16514062 GO_REF:0000107 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:36792666)		 Ensembl
RGD		 PMID:36792666 GO_REF:0000107 NCBI chr 5:72,811,200...72,988,185
Ensembl chr 5:72,811,410...72,988,525 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16514062)		 Ensembl
RGD		 PMID:16514062 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsg cathepsin G involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:3390156)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:3390156 GO_REF:0000024 GO_REF:0000107 NCBI chr15:33,901,230...33,907,596
Ensembl chr15:29,931,003...29,937,353 		JBrowse link
G Emilin2 elastin microfibril interfacer 2 involved_in ISO (PMID:25658937) RGD PMID:25658937 NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352 		JBrowse link
G F11r F11 receptor involved_in ISO (PMID:15344881) RGD PMID:15344881 NCBI chr13:86,406,229...86,429,819
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:18358471 RGD:401938603 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Il6 interleukin 6 acts_upstream_of ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor acts_upstream_of ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Mfsd2b MFSD2 lysolipid transporter B, sphingolipid involved_in ISO (PMID:33863882) RGD PMID:33863882 NCBI chr 6:27,870,182...27,883,768
Ensembl chr 6:27,870,518...27,882,159 		JBrowse link
G Mmrn1 multimerin 1 involved_in ISO (PMID:19175495)
(PMID:20138333)		 RGD PMID:19175495 PMID:20138333 NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474 		JBrowse link
G Pdpn podoplanin involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:17222411), (PMID:17616532), (PMID:18541721), (PMID:20110424)
GO_REF:0000033
(PMID:17616532), (PMID:20110424)		 UniProt
RGD
GO_Central		 PMID:17222411 PMID:17616532 PMID:18541721 PMID:20110424 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig involved_in IBA
ISO		 GO_REF:0000033
(PMID:9171347)		 GO_Central
RGD		 PMID:9171347 GO_REF:0000033 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fundc2 FUN14 domain containing 2 involved_in ISO (PMID:30576423) RGD PMID:30576423 NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345 		JBrowse link
G Gnaq G protein subunit alpha q involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:9296496)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9296496 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:15869579), (PMID:21264222)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:15869579 PMID:21264222 GO_REF:0000024 GO_REF:0000033 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in ISS
IBA		 GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(PMID:9171347)		 UniProt
RGD		 PMID:9171347 GO_REF:0000024 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tec tec protein tyrosine kinase involved_in ISO (PMID:9299487), (PMID:9652744) RGD PMID:9299487 PMID:9652744 NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557 		JBrowse link
regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela2a chymotrypsin like elastase 2A involved_in ISS
ISO		 GO_REF:0000024
(PMID:31358993)		 UniProt
RGD		 PMID:31358993 GO_REF:0000024 NCBI chr 5:159,409,900...159,420,282
Ensembl chr 5:154,126,878...154,136,632 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(PMID:20189992)		 UniProt
RGD		 PMID:20189992 GO_REF:0000024 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Prkca protein kinase C, alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19147982)
GO_REF:0000107
(PMID:12724315)		 UniProt
RGD
Ensembl		 PMID:12724315 PMID:19147982 GO_REF:0000024 GO_REF:0000107 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcq protein kinase C, theta involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19433059)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19433059 GO_REF:0000024 GO_REF:0000107 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:9171347)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:9171347 GO_REF:0000024 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated involved_in ISO (PMID:25947942) RGD PMID:25947942 NCBI chr 1:143,633,167...143,656,228
Ensembl chr 1:134,223,949...134,246,970 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      cell activation 1231
        platelet activation 120
          negative regulation of platelet activation + 16
          platelet aggregation + 80
          positive regulation of platelet activation 13
          regulation of platelet activation + 48
Path 2
Term Annotations click to browse term
  biological_process 20546
    biological regulation 13834
      regulation of biological quality 3452
        regulation of body fluid levels 421
          hemostasis 210
            blood coagulation 206
              platelet activation 120
                negative regulation of platelet activation + 16
                platelet aggregation + 80
                positive regulation of platelet activation 13
                regulation of platelet activation + 48
paths to the root