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ONTOLOGY REPORT - ANNOTATIONS

Term:protein import into mitochondrial matrix
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Accession:GO:0030150 term browser browse the term
Definition:The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.
Synonyms:exact_synonym: mitochondrial matrix protein import;   protein transport into mitochondrial matrix
 broad_synonym: mitochondrial translocation


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protein import into mitochondrial matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC15 DnaJ heat shock protein family (Hsp40) member C15 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:43,023,586...43,114,213
Ensembl chr13:43,023,203...43,114,213 		JBrowse link
G DNAJC19 DnaJ heat shock protein family (Hsp40) member C19 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:180,983,709...180,989,838
Ensembl chr 3:180,983,697...180,989,774 		JBrowse link
G DNLZ DNL-type zinc finger involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:136,359,483...136,363,744
Ensembl chr 9:136,359,480...136,363,744 		JBrowse link
G GRPEL1 GrpE like 1, mitochondrial involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:7,058,895...7,068,064
Ensembl chr 4:7,058,671...7,068,085 		JBrowse link
G GRPEL2 GrpE like 2, mitochondrial involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:149,345,499...149,354,583
Ensembl chr 5:149,345,430...149,354,583 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in IDA (PMID:15644312) BHF-UCL PMID:15644312 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 involved_in IDA (PMID:15644312) BHF-UCL PMID:15644312 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449 		JBrowse link
G PAM16 presequence translocase associated motor 16 involved_in IGI
IBA
IEA		 (PMID:20053669) GO_Central
InterPro		 PMID:20053669 GO_REF:0000002 GO_REF:0000033 NCBI chr16:4,340,251...4,351,321
Ensembl chr16:4,331,549...4,355,607 		JBrowse link
G ROMO1 reactive oxygen species modulator 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:35,699,405...35,700,980
Ensembl chr20:35,699,272...35,700,984 		JBrowse link
G SAMM50 SAMM50 sorting and assembly machinery component involved_in IDA (PMID:15644312) BHF-UCL PMID:15644312 NCBI chr22:43,955,442...43,996,529
Ensembl chr22:43,955,442...44,010,531 		JBrowse link
G TIMM17A translocase of inner mitochondrial membrane 17A involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:201,955,503...201,970,664
Ensembl chr 1:201,955,503...201,970,664 		JBrowse link
G TIMM17B translocase of inner mitochondrial membrane 17B involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr  X:48,893,447...48,898,143
Ensembl chr  X:48,893,447...48,898,143 		JBrowse link
G TIMM21 translocase of inner mitochondrial membrane 21 involved_in IEA
IBA
IMP		 (PMID:23260140) UniProt
GO_Central
InterPro		 PMID:23260140 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr18:74,148,523...74,160,531
Ensembl chr18:74,148,523...74,160,531 		JBrowse link
G TIMM23 translocase of inner mitochondrial membrane 23 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:45,972,489...46,003,742
Ensembl chr10:45,972,489...46,003,742 		JBrowse link
G TIMM23B translocase of inner mitochondrial membrane 23 homolog B involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:49,942,053...49,974,850
Ensembl chr10:49,942,049...49,974,850 		JBrowse link
G TIMM44 translocase of inner mitochondrial membrane 44 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr19:7,926,718...7,943,666
Ensembl chr19:7,926,718...7,943,667 		JBrowse link
G TIMM50 translocase of inner mitochondrial membrane 50 involved_in IBA
IDA		 (PMID:38828998) GO_Central
UniProt		 PMID:38828998 GO_REF:0000033 NCBI chr19:39,480,838...39,493,779
Ensembl chr19:39,480,412...39,493,785 		JBrowse link
G TOMM20 translocase of outer mitochondrial membrane 20 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:235,109,341...235,128,837
Ensembl chr 1:235,109,341...235,128,837 		JBrowse link
G TOMM20L translocase of outer mitochondrial membrane 20 like involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:58,395,930...58,417,080
Ensembl chr14:58,395,928...58,408,702 		JBrowse link
G TOMM22 translocase of outer mitochondrial membrane 22 involved_in IDA (PMID:15644312) BHF-UCL PMID:15644312 NCBI chr22:38,681,957...38,685,421
Ensembl chr22:38,681,957...38,685,421 		JBrowse link
G TOMM40 translocase of outer mitochondrial membrane 40 involved_in IEA
IMP
IBA		 (PMID:15644312) InterPro
UniProt
GO_Central		 PMID:15644312 GO_REF:0000002 GO_REF:0000033 NCBI chr19:44,891,254...44,903,689
Ensembl chr19:44,890,569...44,903,689 		JBrowse link
G TOMM40L translocase of outer mitochondrial membrane 40 like involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:161,226,060...161,230,746
Ensembl chr 1:161,225,939...161,230,746 		JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 involved_in IEA
TAS		 (PMID:15644312) InterPro
BHF-UCL		 PMID:15644312 GO_REF:0000002 NCBI chr 7:22,812,974...22,822,849
Ensembl chr 7:22,812,628...22,822,849 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 involved_in ISS
TAS
IBA		 (PMID:15644312) FlyBase
BHF-UCL
GO_Central		 PMID:15644312 GO_REF:0000024 GO_REF:0000033 NCBI chr 3:100,363,431...100,401,089
Ensembl chr 3:100,363,431...100,401,089 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27210
    cellular process 19786
      transmembrane transport 1769
        mitochondrial transmembrane transport 110
          import into the mitochondrion 58
            protein import into mitochondrial matrix 24
Path 2
Term Annotations click to browse term
  biological_process 27210
    cellular process 19786
      cellular localization 3949
        cellular macromolecule localization 2965
          protein localization 2952
            protein localization to organelle 1208
              protein localization to mitochondrion 147
                establishment of protein localization to mitochondrion 137
                  protein targeting to mitochondrion 114
                    protein import into mitochondrial matrix 24
paths to the root