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ONTOLOGY REPORT - ANNOTATIONS

Term:muscle filament sliding
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Accession:GO:0030049 term browser browse the term
Definition:The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.
Synonyms:xref: Reactome:R-HSA-390522 "Striated Muscle Contraction"

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muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101972165 myosin-7 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936722:967,443...991,530
Ensembl chrNW_004936722:969,384...991,129 		JBrowse link
G Myh8 myosin heavy chain 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:3,278,829...3,307,134
Ensembl chrNW_004936595:3,278,886...3,308,716 		JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936567:3,052,167...3,069,077
Ensembl chrNW_004936567:3,056,845...3,068,887 		JBrowse link
G Tpm1 tropomyosin 1 involved_in ISO PMID:11136687 BHF-UCL PMID:11136687 RGD:1556479 NCBI chrNW_004936471:23,643,645...23,670,775
Ensembl chrNW_004936471:23,643,613...23,670,775 		JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 ISO RGD PMID:17543276 RGD:10398727 NCBI chrNW_004936597:1,735,589...1,751,628
Ensembl chrNW_004936597:1,735,380...1,747,569 		JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mylk2 myosin light chain kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:18,782,890...18,795,942
Ensembl chrNW_004936485:18,782,887...18,795,948 		JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnc1 troponin C1, slow skeletal and cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:3,290,961...3,293,920
Ensembl chrNW_004936473:3,290,913...3,294,132 		JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in ISO PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chrNW_004936567:3,052,167...3,069,077
Ensembl chrNW_004936567:3,056,845...3,068,887 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17429
    multicellular organismal process 7519
      system process 2606
        muscle system process 451
          muscle contraction 319
            muscle filament sliding 7
              negative regulation of muscle filament sliding 1
              positive regulation of muscle filament sliding 0
              regulation of muscle filament sliding + 4
Path 2
Term Annotations click to browse term
  biological_process 17429
    cellular process 17029
      actin filament-based process 783
        actin filament-based movement 123
          actin-mediated cell contraction 101
            actin-myosin filament sliding 8
              muscle filament sliding 7
                negative regulation of muscle filament sliding 1
                positive regulation of muscle filament sliding 0
                regulation of muscle filament sliding + 4
paths to the root