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ONTOLOGY REPORT - ANNOTATIONS

Term:muscle filament sliding
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Accession:GO:0030049 term browser browse the term
Definition:The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.
Synonyms:xref: Reactome:R-HSA-390522 "Striated Muscle Contraction"


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muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100736765 myosin-6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:75,677,666...75,704,486
Ensembl chr 7:75,676,791...75,704,644 		JBrowse link
G MYH7 myosin heavy chain 7 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:75,650,841...75,672,908
Ensembl chr 7:75,648,442...75,673,225 		JBrowse link
G MYH8 myosin heavy chain 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:55,135,651...55,166,983
Ensembl chr12:55,134,844...55,167,748 		JBrowse link
G MYL6 myosin light chain 6 involved_in IC (PMID:16953301) HGNC-UCL PMID:16953301 NCBI chr 5:21,559,226...21,562,418
Ensembl chr 5:21,559,029...21,562,413 		JBrowse link
G TNNT2 troponin T2, cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,749,528...23,759,696
Ensembl chr10:23,749,335...23,763,396 		JBrowse link
G TPM1 tropomyosin 1 involved_in ISO PMID:11136687 BHF-UCL PMID:11136687 RGD:1556479 NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,986...109,020,035 		JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBN1 drebrin 1 ISO RGD PMID:17543276 RGD:10398727 NCBI chr 2:80,480,603...80,495,797
Ensembl chr 2:80,479,460...80,495,796 		JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYLK2 myosin light chain kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:35,499,828...35,513,096
Ensembl chr17:35,499,887...35,513,093 		JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNNC1 troponin C1, slow skeletal and cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:34,591,571...34,594,320
Ensembl chr13:34,591,386...34,594,337 		JBrowse link
G TNNT2 troponin T2, cardiac type involved_in ISO PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chr10:23,749,528...23,759,696
Ensembl chr10:23,749,335...23,763,396 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    multicellular organismal process 8782
      system process 3604
        muscle system process 475
          muscle contraction 336
            muscle filament sliding 9
              negative regulation of muscle filament sliding 1
              positive regulation of muscle filament sliding 0
              regulation of muscle filament sliding + 4
Path 2
Term Annotations click to browse term
  biological_process 18944
    cellular process 18487
      actin filament-based process 825
        actin filament-based movement 124
          actin-mediated cell contraction 101
            actin-myosin filament sliding 10
              muscle filament sliding 9
                negative regulation of muscle filament sliding 1
                positive regulation of muscle filament sliding 0
                regulation of muscle filament sliding + 4
paths to the root