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ONTOLOGY REPORT - ANNOTATIONS

Term:muscle filament sliding
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Accession:GO:0030049 term browser browse the term
Definition:The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.
Synonyms:xref: Reactome:R-HSA-390522 "Striated Muscle Contraction"

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muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103231478 myosin-6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:23,753,251...23,780,822
Ensembl chr29:23,753,309...23,778,107 		JBrowse link
G LOC103231480 myosin-7 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:23,783,610...23,804,981
Ensembl chr29:23,783,557...23,799,771 		JBrowse link
G LOC103242383 myosin-2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,863,336...9,891,271 JBrowse link
G LOC103242386 myosin-8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,733,585...9,765,740
Ensembl chr16:9,733,717...9,763,255 		JBrowse link
G LOC119618298 myosin-7 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118
G TNNT2 troponin T2, cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
G TPM1 tropomyosin 1 involved_in ISO PMID:11136687 BHF-UCL PMID:11136687 RGD:1556479 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135 		JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBN1 drebrin 1 ISO RGD PMID:17543276 RGD:10398727 NCBI chr23:79,468,010...79,484,603
Ensembl chr23:79,467,647...79,484,592 		JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYLK2 myosin light chain kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:36,207,013...36,223,292
Ensembl chr 2:36,207,901...36,223,307 		JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNNC1 troponin C1, slow skeletal and cardiac type involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,816,603...13,819,572
Ensembl chr22:13,816,222...13,819,518 		JBrowse link
G TNNT2 troponin T2, cardiac type involved_in ISO PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chr25:28,035,563...28,054,322
Ensembl chr25:28,040,087...28,054,120 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    multicellular organismal process 7540
      system process 2242
        muscle system process 477
          muscle contraction 341
            muscle filament sliding 10
              negative regulation of muscle filament sliding 1
              positive regulation of muscle filament sliding 0
              regulation of muscle filament sliding + 4
Path 2
Term Annotations click to browse term
  biological_process 19829
    cellular process 19347
      actin filament-based process 819
        actin filament-based movement 127
          actin-mediated cell contraction 104
            actin-myosin filament sliding 11
              muscle filament sliding 10
                negative regulation of muscle filament sliding 1
                positive regulation of muscle filament sliding 0
                regulation of muscle filament sliding + 4
paths to the root