ONTOLOGY REPORT - ANNOTATIONS
Term: wide pore channel activity
Accession: GO:0022829
browse the term
Definition: Enables the energy-independent facilitated diffusion of propanediol through a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.
Synonyms: exact_synonym: non-gated, wide pore channel activity
narrow_synonym: gap junction activity
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GSDMA
gasdermin A
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr16:66,193,042...66,209,375
Ensembl chr16:66,194,174...66,205,549
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GSDMB
gasdermin B
enables
ISO
(PMID:32299851), (PMID:34022140), (PMID:36599845), (PMID:36899106), (PMID:36991122), (PMID:36991125)
UniProt
PMID:32299851 PMID:34022140 PMID:36599845 PMID:36899106 PMID:36991122 PMID:36991125 More...
NCBI chr16:66,253,562...66,266,391
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GSDMC
gasdermin C
enables
ISO
(PMID:32929201), (PMID:34012073) (PMID:34290141)
UniProt
PMID:32929201 PMID:34012073 PMID:34290141
NCBI chr 8:124,247,934...124,291,282
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GSDMD
gasdermin D
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 8:137,778,290...137,783,542
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GSDME
gasdermin E
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr21:33,611,068...33,671,497
Ensembl chr21:33,612,013...33,672,461
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LOC103234994
macrophage-expressed gene 1 protein
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:14,349,756...14,354,095
Ensembl chr 1:14,349,954...14,352,104
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PANX1
pannexin 1
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 1:85,356,507...85,413,146
Ensembl chr 1:85,356,610...85,409,275
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PANX2
pannexin 2
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr19:32,662,350...32,671,536
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PANX3
pannexin 3
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 1:115,757,147...115,767,034
Ensembl chr 1:115,757,901...115,766,295
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PRF1
perforin 1
enables
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chr 9:60,692,544...60,698,000
Ensembl chr 9:60,692,600...60,698,465
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GJA1
gap junction protein alpha 1
enables
ISO IEA
RGD TreeGrafter Ensembl
PMID:15048573 PMID:16731531
GO_REF:0000107 GO_REF:0000118 RGD:1580399 RGD:1582674
NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339
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GJA10
gap junction protein alpha 10
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr13:14,646,091...14,716,787
Ensembl chr13:14,651,295...14,652,926
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GJA3
gap junction protein alpha 3
enables
ISO IEA
RGD TreeGrafter InterPro
PMID:1659572
GO_REF:0000002 GO_REF:0000118 RGD:728416
NCBI chr 3:820,352...852,003
Ensembl chr 3:846,982...848,286
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GJA4
gap junction protein alpha 4
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr20:98,092,282...98,095,036
Ensembl chr20:98,092,785...98,093,786
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GJA5
gap junction protein alpha 5
ISO
RGD
PMID:1328644
RGD:728713
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GJA8
gap junction protein alpha 8
contributes_to enables
ISO IEA
RGD TreeGrafter Ensembl
PMID:16123426
GO_REF:0000107 GO_REF:0000118 RGD:1598965
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GJA9
gap junction protein alpha 9
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr20:94,009,063...94,016,927
Ensembl chr20:94,014,888...94,016,435
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GJB1
gap junction protein beta 1
enables
ISO IEA
RGD TreeGrafter
PMID:12119284
GO_REF:0000118 RGD:728476
NCBI chr X:61,013,991...61,019,222
Ensembl chr X:61,017,716...61,018,567
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GJB2
gap junction protein beta 2
enables
ISO IEA
RGD Ensembl TreeGrafter
PMID:23232329
GO_REF:0000107 GO_REF:0000118 RGD:7349364
NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059
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GJB3
gap junction protein beta 3
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr20:98,100,285...98,106,517
Ensembl chr20:98,102,413...98,103,225
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GJB4
gap junction protein beta 4
enables
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr20:98,125,073...98,126,343
Ensembl chr20:98,125,345...98,126,145
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GJB5
gap junction protein beta 5
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr20:98,128,901...98,132,640
Ensembl chr20:98,129,262...98,130,083
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GJB6
gap junction protein beta 6
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr 3:775,410...783,770
Ensembl chr 3:782,251...783,036
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GJB7
gap junction protein beta 7
enables
ISO
(PMID:12064583)
UniProt
PMID:12064583
NCBI chr13:11,780,295...11,789,625
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GJB7
gap junction protein beta 7
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
Ensembl chr13:11,781,545...11,782,198
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GJC1
gap junction protein gamma 1
enables
ISO IEA
RGD TreeGrafter
PMID:11668048
GO_REF:0000118 RGD:628534
NCBI chr16:61,575,851...61,596,488
Ensembl chr16:61,594,885...61,596,075
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GJC2
gap junction protein gamma 2
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr25:1,568,664...1,579,279
Ensembl chr25:1,569,427...1,570,752
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GJC3
gap junction protein gamma 3
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr28:13,153,447...13,160,951
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GJD2
gap junction protein delta 2
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr26:48,149,568...48,152,466
Ensembl chr26:48,149,755...48,153,660
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GJD3
gap junction protein delta 3
ISO
RGD
PMID:23385797
RGD:7364769
NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862
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GJD4
gap junction protein delta 4
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 9:34,856,892...34,886,231
Ensembl chr 9:34,883,069...34,886,136
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PANX1
pannexin 1
ISO
RGD
PMID:14597722
RGD:1299639
NCBI chr 1:85,356,507...85,413,146
Ensembl chr 1:85,356,610...85,409,275
G
PANX2
pannexin 2
ISO
RGD
PMID:14597722
RGD:1299639
NCBI chr19:32,662,350...32,671,536
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl
GO_REF:0000107
G
GJC1
gap junction protein gamma 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr16:61,575,851...61,596,488
Ensembl chr16:61,594,885...61,596,075
G
GJD3
gap junction protein delta 3
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl
GO_REF:0000107
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl
GO_REF:0000107
G
GJA1
gap junction protein alpha 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339
G
GJB2
gap junction protein beta 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059
G
GJB6
gap junction protein beta 6
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 3:775,410...783,770
Ensembl chr 3:782,251...783,036
G
GJC2
gap junction protein gamma 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr25:1,568,664...1,579,279
Ensembl chr25:1,569,427...1,570,752
G
GJA1
gap junction protein alpha 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339
G
GJA3
gap junction protein alpha 3
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 3:820,352...852,003
Ensembl chr 3:846,982...848,286
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl
GO_REF:0000107
G
PANX1
pannexin 1
NOT|enables
ISO
PMID:17715132
UniProt
PMID:17715132
RGD:15090844
NCBI chr 1:85,356,507...85,413,146
Ensembl chr 1:85,356,610...85,409,275
G
PANX3
pannexin 3
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:115,757,147...115,767,034
Ensembl chr 1:115,757,901...115,766,295
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BAK1
BCL2 antagonist/killer 1
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr17:38,492,776...38,502,534
Ensembl chr17:38,492,858...38,501,281
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VDAC1
voltage dependent anion channel 1
enables
IEA
UniProt
GO_REF:0000043
NCBI chr23:36,783,670...36,817,071
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VDAC2
voltage dependent anion channel 2
enables
IEA
UniProt
GO_REF:0000043
NCBI chr 9:56,141,153...56,160,378
Ensembl chr 9:56,136,756...56,157,173
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VDAC3
voltage dependent anion channel 3
enables
IEA
UniProt
GO_REF:0000043
NCBI chr 8:40,388,485...40,402,637
Ensembl chr 8:40,388,423...40,403,598
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