regulation of cell-cell adhesion - Ontology Report

GO_REF:0000033 GO_REF:0000107

NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747

CD24 molecule

acts_upstream_of_or_within
involved_in

(PMID:8117278)

PMID:8117278

GO_REF:0000033

NCBI chr12:64,239,957...64,245,114

CELSR2

cadherin EGF LAG seven-pass G-type receptor 2

involved_in

PMID:15955893

NCBI chr 6:42,547,638...42,573,407
Ensembl chr 6:42,548,983...42,573,962

EFNA5

ephrin A5

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr 3:4,272,138...4,546,527
Ensembl chr 3:4,272,518...4,542,049

EPHA7

EPH receptor A7

involved_in

GO_REF:0000107

NCBI chr12:52,134,775...52,305,163
Ensembl chr12:52,137,605...52,305,162

EPHB3

EPH receptor B3

involved_in

GO_REF:0000107

NCBI chr34:17,422,746...17,433,769
Ensembl chr34:17,422,842...17,462,954

fucosyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303

ITGAL

integrin subunit alpha L

acts_upstream_of_or_within

(PMID:8117278)

PMID:8117278

NCBI chr 6:17,605,611...17,645,134
Ensembl chr 6:17,605,760...17,644,986

Janus kinase 2

involved_in

GO_REF:0000117

NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997

Janus kinase 3

involved_in

GO_REF:0000117

NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805

LEF1

lymphoid enhancer binding factor 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019

MINK1

misshapen like kinase 1

involved_in

GO_REF:0000107

NCBI chr 5:31,707,975...31,718,013
Ensembl chr 5:31,708,553...31,749,842

NRARP

NOTCH regulated ankyrin repeat protein

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:48,394,568...48,396,849
Ensembl chr 9:48,394,754...48,395,098

PKHD1

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

involved_in

IMP

(PMID:31398719)

PMID:31398719

NCBI chr12:19,280,866...19,744,669
Ensembl chr12:19,286,822...19,744,141

PODXL

podocalyxin like

involved_in

InterPro

GO_REF:0000002

NCBI chr14:5,614,006...5,625,360
Ensembl chr14:5,590,478...5,625,360

RCL1

RNA terminal phosphate cyclase like 1

involved_in

GO_REF:0000117

NCBI chr 1:93,144,164...93,204,233
Ensembl chr 1:93,142,635...93,435,997

SFN

stratifin

involved_in

(PMID:29678907)

PMID:29678907

NCBI chr 2:73,268,289...73,269,663
Ensembl chr 2:73,268,791...73,269,537

SRC

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077

WNT4

Wnt family member 4

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111

ZDHHC2

zDHHC palmitoyltransferase 2

involved_in

(PMID:18508921)

PMID:18508921

NCBI chr16:40,496,469...40,551,979
Ensembl chr16:40,506,524...40,543,360

blood vessel endothelial cell delamination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TRPV4

transient receptor potential cation channel subfamily V member 4

involved_in

GO_REF:0000107

NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165

CD4-positive, alpha-beta T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD81

CD81 molecule

involved_in

(PMID:22307619)

PMID:22307619

NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868

TNF superfamily member 4

involved_in

(PMID:20639485)

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

corneocyte desquamation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCA12

ATP binding cassette subfamily A member 12

involved_in

GO_REF:0000107

NCBI chr37:22,136,732...22,306,917
Ensembl chr37:22,138,245...22,405,736

CDSN

corneodesmosin

involved_in

(PMID:26014679)

CAFA

PMID:26014679

NCBI chr12:819,488...824,015
Ensembl chr12:820,467...823,986

delamination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKNA

AT-hook transcription factor

involved_in

GO_REF:0000107

NCBI chr11:68,561,522...68,600,724
Ensembl chr11:68,562,145...68,598,557

endothelial to hematopoietic transition

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SPI1

Spi-1 proto-oncogene

involved_in

GO_REF:0000107

NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727

negative regulation of activated T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARG1

arginase 1

involved_in

(PMID:19360123)

PMID:19360123

NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305

CASP3

caspase 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505

CD274 molecule

involved_in

PMID:12538684 PMID:17489864

(PMID:12538684)
(PMID:17489864)

UniProt
AgBase

NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522

CRTAM

cytotoxic and regulatory T cell molecule

involved_in

GO_REF:0000107

NCBI chr 5:11,458,360...11,485,469
Ensembl chr 5:11,458,008...11,485,448

IDO1

indoleamine 2,3-dioxygenase 1

acts_upstream_of_or_within

(PMID:18077788)

PMID:18077788

NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048

LAPTM5

lysosomal protein transmembrane 5

involved_in

GO_REF:0000107

NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073

galectin 9

involved_in

(PMID:23817958)

PMID:23817958

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

LOC100855640

butyrophilin subfamily 2 member A2

acts_upstream_of_or_within
involved_in

(PMID:23589618)

MGI
Ensembl

PMID:23589618

GO_REF:0000107

NCBI chr35:24,251,221...24,265,040
Ensembl chr35:24,251,799...24,262,496

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:19380766)

PMID:19380766

NCBI chr 1:102,779,562...102,786,924

LRRC32

leucine rich repeat containing 32

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr21:22,051,140...22,059,714
Ensembl chr21:22,051,920...22,057,632

MIR181C

microRNA mir-181c

acts_upstream_of

(PMID:21112091)

PMID:21112091

NCBI chr20:48,593,343...48,593,403
Ensembl chr20:48,593,325...48,593,421

programmed cell death 1 ligand 2

involved_in

GO_REF:0000107

NCBI chr 1:93,631,676...93,698,560
Ensembl chr 1:93,631,979...93,689,266

PRKAR1A

protein kinase cAMP-dependent type I regulatory subunit alpha

involved_in

GO_REF:0000107

NCBI chr 9:15,180,940...15,203,035
Ensembl chr 9:15,181,393...15,200,683

PRNP

prion protein

involved_in

GO_REF:0000107

NCBI chr24:16,845,224...16,862,319
Ensembl chr24:16,846,207...16,859,815

RC3H1

ring finger and CCCH-type domains 1

involved_in

GO_REF:0000107

NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174

SCRIB

scribble planar cell polarity protein

involved_in

GO_REF:0000107

NCBI chr13:37,356,405...37,374,765
Ensembl chr13:37,356,405...37,374,681

negative regulation of alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA2A

adenosine A2a receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598

V-set immunoregulatory receptor

involved_in

GO_REF:0000033

NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687

negative regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GLI3

GLI family zinc finger 3

involved_in

GO_REF:0000107

NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

sonic hedgehog signaling molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

negative regulation of alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BTLA

B and T lymphocyte associated

acts_upstream_of_or_within

(PMID:15568026)

PMID:15568026

NCBI chr33:16,978,173...17,006,837
Ensembl chr33:16,979,634...17,007,033

CLEC4G

C-type lectin domain family 4 member G

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:52,476,162...52,480,341
Ensembl chr20:52,476,200...52,479,930

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

TNF receptor superfamily member 14

involved_in

GO_REF:0000033

NCBI chr 5:57,386,190...57,416,864
Ensembl chr 5:57,411,529...57,416,512

negative regulation of calcium-independent cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP2

bone morphogenetic protein 2

involved_in

GO_REF:0000107

NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217

negative regulation of CD4-positive, alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LOC484314

T-cell-interacting, activating receptor on myeloid cells protein 1-like

involved_in

(PMID:26311901)

PMID:26311901

NCBI chr 1:103,182,052...103,187,416

TWSG1

twisted gastrulation BMP signaling modulator 1

involved_in

GO_REF:0000107

NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325

negative regulation of CD4-positive, alpha-beta T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD160

CD160 molecule

involved_in

(PMID:18193050)

PMID:18193050

NCBI chr17:58,548,137...58,564,077
Ensembl chr17:58,555,851...58,563,341

negative regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBFB

core-binding factor subunit beta

involved_in

(PMID:18258917)

NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168

HMGB1

high mobility group box 1

involved_in

GO_REF:0000107

NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165

RUNX1

RUNX family transcription factor 1

involved_in

(PMID:18258917)

NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839

RUNX3

RUNX family transcription factor 3

involved_in

(PMID:18258917)

negative regulation of CD4-positive, alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARG2

arginase 2

involved_in

GO_REF:0000107

NCBI chr 8:41,588,051...41,619,406
Ensembl chr 8:41,588,150...41,619,402

CBLB

Cbl proto-oncogene B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810

CD274 molecule

involved_in

(PMID:24691993)

PMID:24691993

NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522

CD44 molecule

involved_in

(PMID:25065622)

NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

ITCH

itchy E3 ubiquitin protein ligase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:23,476,619...23,630,574
Ensembl chr24:23,476,736...23,627,469

galectin 9

involved_in

GO_REF:0000033

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

LOC484314

T-cell-interacting, activating receptor on myeloid cells protein 1-like

involved_in

(PMID:26311901)

PMID:26311901

NCBI chr 1:103,182,052...103,187,416

lymphotactin

involved_in

(PMID:10887101)

PMID:10887101

NCBI chr 7:29,986,433...29,991,096

NDFIP1

Nedd4 family interacting protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:36,978,148...37,065,247
Ensembl chr 2:36,961,024...37,064,303

TNF receptor superfamily member 14

acts_upstream_of_or_within

(PMID:15568026)

PMID:15568026

NCBI chr 5:57,386,190...57,416,864
Ensembl chr 5:57,411,529...57,416,512

TWSG1

twisted gastrulation BMP signaling modulator 1

involved_in

GO_REF:0000107

NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325

V-set immunoregulatory receptor

involved_in
acts_upstream_of_or_within

(PMID:21383057)

Ensembl
MGI

PMID:21383057

GO_REF:0000107

NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687

negative regulation of CD8-positive, alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD274 molecule

involved_in

(PMID:28813410), (PMID:28813417)
(PMID:28813417)

PMID:28813410 PMID:28813417

NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522

DAPL1

death associated protein like 1

involved_in

GO_REF:0000107

NCBI chr36:4,678,544...4,698,711
Ensembl chr36:4,678,563...4,698,710

HFE

homeostatic iron regulator

involved_in

GO_REF:0000107

NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413

negative regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC4A2

solute carrier family 4 member 2

involved_in

(PMID:24515893)

PMID:24515893

NCBI chr16:15,111,078...15,126,618
Ensembl chr16:15,111,116...15,126,617

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557

zinc finger and BTB domain containing 7B

involved_in

GO_REF:0000107

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

negative regulation of CD8-positive, alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC4A2

solute carrier family 4 member 2

involved_in

(PMID:24515893)

PMID:24515893

NCBI chr16:15,111,078...15,126,618
Ensembl chr16:15,111,116...15,126,617

V-set immunoregulatory receptor

involved_in

GO_REF:0000107

NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687

negative regulation of cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307

ABL2

ABL proto-oncogene 2, non-receptor tyrosine kinase

acts_upstream_of_or_within

(PMID:24367707)

PMID:24367707

NCBI chr 7:20,696,659...20,735,362
Ensembl chr 7:20,700,144...20,727,410

B4GALNT2

beta-1,4-N-acetyl-galactosaminyltransferase 2

involved_in

GO_REF:0000107

NCBI chr 9:25,314,845...25,344,644
Ensembl chr 9:25,294,223...25,344,382

CDH1

cadherin 1

involved_in

GO_REF:0000107

NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878

EPB41L5

erythrocyte membrane protein band 4.1 like 5

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:29,916,994...30,063,243
Ensembl chr19:29,921,636...30,063,216

GTPBP4

GTP binding protein 4

involved_in

GO_REF:0000107

NCBI chr 2:33,936,629...33,955,947
Ensembl chr 2:33,936,637...34,024,769

JAG1

jagged canonical Notch ligand 1

involved_in

GO_REF:0000107

NCBI chr24:11,656,926...11,693,146
Ensembl chr24:11,657,416...11,692,199

Janus kinase 2

gastrin-induced

NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997

LOC119878551

kunitz-type protease inhibitor 2-like

acts_upstream_of_or_within

GO_REF:0000107

MUC21

mucin 21, cell surface associated

acts_upstream_of_or_within

(PMID:20388707)

PMID:20388707

NCBI chr12:735,342...780,044

MUC4

mucin 4, cell surface associated

NCBI chr33:29,061,372...29,084,938
Ensembl chr33:29,063,096...29,111,802

NF2

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

involved_in

GO_REF:0000107

NCBI chr26:22,816,869...22,896,103
Ensembl chr26:22,816,551...22,894,196

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

gastrin-induced

NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970

PODXL

podocalyxin like

involved_in

ISS
IBA

UniProt
GO_Central

GO_REF:0000024 GO_REF:0000033

NCBI chr14:5,614,006...5,625,360
Ensembl chr14:5,590,478...5,625,360

PTK2

protein tyrosine kinase 2

involved_in

(PMID:21703394)

PMID:21703394

NCBI chr13:35,302,439...35,541,336
Ensembl chr13:35,303,380...35,541,294

SPINT2

serine peptidase inhibitor, Kunitz type 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:114,699,050...114,727,802
Ensembl chr 1:114,699,241...114,727,763

TNR

tenascin R

acts_upstream_of_or_within

(PMID:16831557)
(PMID:15034584)

PMID:15034584 PMID:16831557

NCBI chr 7:23,721,227...24,125,183
Ensembl chr 7:24,019,095...24,122,530

VEGFA

vascular endothelial growth factor A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965

WNT1

Wnt family member 1

involved_in

GO_REF:0000107

NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060

negative regulation of cell-cell adhesion mediated by cadherin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B9 domain containing 2

involved_in

(PMID:18593713)

PMID:18593713

NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885

BMP6

bone morphogenetic protein 6

involved_in

GO_REF:0000107

NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845

EPCAM

epithelial cell adhesion molecule

involved_in

GO_REF:0000107

NCBI chr10:49,446,165...49,498,690
Ensembl chr10:49,485,746...49,498,475

MAD2L2

mitotic arrest deficient 2 like 2

involved_in

GO_REF:0000107

NCBI chr 2:84,539,724...84,549,402
Ensembl chr 2:84,545,226...84,549,356

NEXMIF

neurite extension and migration factor

involved_in

RGD
GO_Central

PMID:24071057

GO_REF:0000033 RGD:13442493

NCBI chr X:57,986,884...58,120,453
Ensembl chr X:57,992,476...58,013,478

NOTCH1

notch receptor 1

involved_in

GO_REF:0000107

NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277

NOTCH4

notch receptor 4

involved_in

(PMID:17984306)

PMID:17984306

NCBI chr12:1,585,249...1,608,721
Ensembl chr12:1,587,918...1,607,760

PPM1F

protein phosphatase, Mg2+/Mn2+ dependent 1F

involved_in

GO_REF:0000107

NCBI chr26:31,162,810...31,193,586
Ensembl chr26:31,166,593...31,193,587

RGCC

regulator of cell cycle

involved_in
acts_upstream_of

(PMID:19158077)

Ensembl
BHF-UCL

PMID:19158077

GO_REF:0000107

NCBI chr22:9,199,204...9,209,297

transforming growth factor beta 1

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885

VEGFA

vascular endothelial growth factor A

involved_in

GO_REF:0000107

NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965

negative regulation of cell-cell adhesion mediated by integrin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SWAP70

switching B cell complex subunit SWAP70

involved_in

GO_REF:0000107

NCBI chr21:32,910,547...32,985,617
Ensembl chr21:32,910,563...32,984,580

WNK1

WNK lysine deficient protein kinase 1

involved_in

GO_REF:0000107

NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806

negative regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:16493035)

PMID:16493035

NCBI chr 1:102,779,562...102,786,924

negative regulation of erythrocyte aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD24 molecule

acts_upstream_of_or_within

(PMID:9028339)

PMID:9028339

NCBI chr12:64,239,957...64,245,114

negative regulation of establishment of T cell polarity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RIPOR2

RHO family interacting cell polarization regulator 2

involved_in

(PMID:23241886)

PMID:23241886

NCBI chr35:22,823,053...23,041,765
Ensembl chr35:22,824,106...23,041,743

negative regulation of heterotypic cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADIPOQ

adiponectin, C1Q and collagen domain containing

involved_in

IEA
ISS

GO_REF:0000024 GO_REF:0000107

NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844

APOA1

apolipoprotein A1

involved_in

GO_REF:0000107

NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943

IL10

interleukin 10

involved_in

GO_REF:0000107

NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057

IL1RN

interleukin 1 receptor antagonist

involved_in

GO_REF:0000107

NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329

KLF4

KLF transcription factor 4

involved_in

GO_REF:0000107

NCBI chr11:62,881,840...62,886,676
Ensembl chr11:62,882,767...62,928,251

MAP2K5

mitogen-activated protein kinase kinase 5

involved_in

PMID:20551324

NCBI chr30:31,665,032...31,920,792
Ensembl chr30:31,664,564...31,920,751

MAPK7

mitogen-activated protein kinase 7

involved_in

GO_REF:0000107

NCBI chr 5:40,831,949...40,836,990
Ensembl chr 5:40,831,947...40,836,505

MBP

myelin basic protein

involved_in

GO_REF:0000107

NCBI chr 1:2,841,801...2,952,553
Ensembl chr 1:2,846,589...2,951,860

MIR221

microRNA mir-221

involved_in

(PMID:20110463)

PMID:20110463

NCBI chr X:39,523,890...39,523,951
Ensembl chr X:39,523,885...39,523,954

MYADM

myeloid associated differentiation marker

involved_in

GO_REF:0000107

NCBI chr 1:103,315,606...103,322,329

WNK1

WNK lysine deficient protein kinase 1

involved_in

GO_REF:0000107

NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806

negative regulation of homotypic cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCM2L

CCM2 like scaffold protein

acts_upstream_of_or_within

(PMID:22898778)

PMID:22898778

NCBI chr24:21,437,838...21,455,879
Ensembl chr24:21,437,925...21,455,000

MAP2K1

mitogen-activated protein kinase kinase 1

IEC6 cells

NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479

RDX

radixin

involved_in

GO_REF:0000107

NCBI chr 5:22,555,913...22,642,822
Ensembl chr 5:22,571,286...22,642,811

ZNF703

zinc finger protein 703

involved_in

(PMID:21317240)

PMID:21317240

NCBI chr16:27,669,506...27,673,732
Ensembl chr16:27,670,897...27,673,803

negative regulation of immature T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GNRH1

gonadotropin releasing hormone 1

NCBI chr25:32,038,631...32,043,192
Ensembl chr25:32,039,613...32,043,028

negative regulation of immature T cell proliferation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP4

bone morphogenetic protein 4

involved_in

GO_REF:0000107

NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557

CDKN2A

cyclin dependent kinase inhibitor 2A

involved_in

(PMID:15964995)

HGNC-UCL

PMID:15964995

NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379

CLEC4G

C-type lectin domain family 4 member G

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:52,476,162...52,480,341
Ensembl chr20:52,476,200...52,479,930

ERBB2

erb-b2 receptor tyrosine kinase 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

TMEM131L

transmembrane 131 like

involved_in

GO_REF:0000107

NCBI chr15:51,268,897...51,427,347
Ensembl chr15:51,268,855...51,427,212

negative regulation of leukocyte adhesion to arterial endothelial cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KLF4

KLF transcription factor 4

involved_in

GO_REF:0000107

NCBI chr11:62,881,840...62,886,676
Ensembl chr11:62,882,767...62,928,251

negative regulation of leukocyte adhesion to vascular endothelial cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MIR125A

microRNA mir-125a

acts_upstream_of_or_within

(PMID:30670152)

PMID:30670152

NCBI chr 1:105,400,273...105,400,332
Ensembl chr 1:105,400,270...105,400,337

MIR221

microRNA mir-221

involved_in

(PMID:21310411)

PMID:21310411

NCBI chr X:39,523,890...39,523,951
Ensembl chr X:39,523,885...39,523,954

MIR222

microRNA mir-222

involved_in

(PMID:21310411)

PMID:21310411

NCBI chr X:39,524,519...39,524,608
Ensembl chr X:39,524,519...39,524,608

MIR31

microRNA mir-31

involved_in

(PMID:19949084)

PMID:19949084

NCBI chr11:40,904,438...40,904,496
Ensembl chr11:40,904,437...40,904,503

MIRLET7E

microRNA let-7e

acts_upstream_of_or_within

(PMID:30670152)

PMID:30670152

NCBI chr 1:105,400,740...105,400,806
Ensembl chr 1:105,400,730...105,400,816

MIRLET7G

microRNA let-7g

involved_in

(PMID:24291274)

PMID:24291274

NCBI chr20:37,501,074...37,501,152
Ensembl chr20:37,501,054...37,501,160

negative regulation of leukocyte cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADTRP

androgen dependent TFPI regulating protein

involved_in

GO_REF:0000107

NCBI chr35:11,300,186...11,362,893
Ensembl chr35:11,300,887...11,362,101

AKT1

AKT serine/threonine kinase 1

involved_in

GO_REF:0000107

NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193

ASS1

argininosuccinate synthase 1

involved_in

GO_REF:0000107

NCBI chr 9:53,425,228...53,478,007
Ensembl chr 9:53,425,448...53,477,904

MIA3

MIA SH3 domain ER export factor 3

involved_in

GO_REF:0000107

NCBI chr38:16,880,411...16,936,368
Ensembl chr38:16,879,740...16,935,844

PPARA

peroxisome proliferator activated receptor alpha

involved_in

(PMID:21636785)

PMID:21636785

NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146

WNK1

WNK lysine deficient protein kinase 1

involved_in

GO_REF:0000107

NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806

negative regulation of leukocyte tethering or rolling

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCL21

C-C motif chemokine ligand 21

involved_in

GO_REF:0000107

NCBI chr11:51,375,107...51,375,790

CCL25

C-C motif chemokine ligand 25

involved_in

(PMID:18308860)

PMID:18308860

NCBI chr20:52,689,674...52,722,291
Ensembl chr20:52,712,979...52,722,018

CCL28

C-C motif chemokine ligand 28

involved_in

GO_REF:0000107

NCBI chr 4:66,567,139...66,597,310
Ensembl chr 4:66,566,989...66,597,459

CXCL12

C-X-C motif chemokine ligand 12

involved_in

GO_REF:0000107

NCBI chr28:2,895,916...2,903,543

selectin L

NCBI chr 7:28,906,752...28,927,959
Ensembl chr 7:28,906,809...29,094,008

negative regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGL2

fibrinogen like 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr18:17,328,794...17,335,429
Ensembl chr18:17,331,780...17,335,401

IL29L

interleukin 29-like

involved_in

(PMID:19346497)

PMID:19346497

NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017

negative regulation of NK T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD300A

CD300a molecule

involved_in

(PMID:10540326)

PMID:10540326

NCBI chr 9:5,952,428...5,976,328

LGALS3

galectin 3

involved_in

GO_REF:0000107

NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705

negative regulation of NK T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

zinc finger and BTB domain containing 7B

involved_in

GO_REF:0000107

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

negative regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADAMTS18

ADAM metallopeptidase with thrombospondin type 1 motif 18

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:73,769,462...73,907,024
Ensembl chr 5:73,772,114...73,905,264

ALOX12

arachidonate 12-lipoxygenase, 12S type

involved_in

GO_REF:0000107

NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119

C1QTNF1

C1q and TNF related 1

involved_in

GO_REF:0000107

NCBI chr 9:2,401,369...2,405,595
Ensembl chr 9:2,402,945...2,404,053

CD9

CD9 molecule

involved_in

GO_REF:0000107

NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576

CEA cell adhesion molecule 1

involved_in

(PMID:19008452)

PMID:19008452

NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830

PRKCD

protein kinase C delta

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191

PRKG1

protein kinase cGMP-dependent 1

involved_in

GO_REF:0000107

NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729

SERPINE2

serpin family E member 2

involved_in

(PMID:19855083)

PMID:19855083

NCBI chr37:29,699,551...29,750,151
Ensembl chr37:29,700,024...29,724,228

SH2B3

SH2B adaptor protein 3

involved_in

GO_REF:0000107

NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204

TMX1

thioredoxin related transmembrane protein 1

involved_in

GO_REF:0000107

NCBI chr 8:27,541,407...27,556,058
Ensembl chr 8:27,541,460...27,554,681

UBASH3B

ubiquitin associated and SH3 domain containing B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675

negative regulation of positive thymic T cell selection

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PTPN2

protein tyrosine phosphatase non-receptor type 2

involved_in

GO_REF:0000107

NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719

negative regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD44 molecule

involved_in

(PMID:25065622)

NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107

CTLA4

cytotoxic T-lymphocyte associated protein 4

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874

HSPB1

heat shock protein family B (small) member 1

NCBI chr 6:7,487,164...7,488,576
Ensembl chr 6:7,487,250...7,488,576

IRF1

interferon regulatory factor 1

involved_in

GO_REF:0000107

NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608

LAG3

lymphocyte activating 3

involved_in

GO_REF:0000107

NCBI chr27:38,260,673...38,266,771
Ensembl chr27:38,260,674...38,265,819

MDK

midkine

involved_in

(PMID:22323540)

microRNA mir-21

involved_in

(PMID:22387553)

NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624

MIR30B

microRNA mir-30b

involved_in

(PMID:22387553)

NCBI chr13:30,906,038...30,906,097
Ensembl chr13:30,906,038...30,906,097

TNF superfamily member 4

involved_in

(PMID:18713990)

PMID:18713990

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

TUG1

taurine up-regulated 1

NCBI chr26:23,993,804...24,003,508

negative regulation of T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

B9 domain containing 2

acts_upstream_of_or_within

(PMID:12646629)

PMID:12646629

NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885

CSK

C-terminal Src kinase

involved_in

GO_REF:0000107

NCBI chr30:37,851,269...37,870,382
Ensembl chr30:37,852,046...37,870,378

CTSG

cathepsin G

involved_in

GO_REF:0000107

NCBI chr 8:4,483,327...4,485,933
Ensembl chr 8:4,470,577...4,512,628

DUSP22

dual specificity phosphatase 22

acts_upstream_of_or_within

(PMID:24714587)

PMID:24714587

NCBI chr35:678,320...733,225
Ensembl chr35:678,155...732,397

DUSP3

dual specificity phosphatase 3

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr 9:19,518,302...19,531,000
Ensembl chr 9:19,518,746...19,527,624

FGL1

fibrinogen like 1

involved_in

GO_REF:0000033

NCBI chr16:41,161,314...41,191,282
Ensembl chr16:41,161,394...41,179,791

GPNMB

glycoprotein nmb

involved_in

(PMID:19350579)

ParkinsonsUK-UCL

PMID:19350579

NCBI chr14:36,919,184...36,947,023
Ensembl chr14:36,919,296...36,946,643

interleukin 4

acts_upstream_of_or_within

(PMID:18997793)

PMID:18997793

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

IL4I1

interleukin 4 induced 1

involved_in

GO_REF:0000107

NCBI chr 1:106,636,282...106,673,438
Ensembl chr 1:106,657,477...106,673,422

ILDR2

immunoglobulin like domain containing receptor 2

involved_in

GO_REF:0000107

NCBI chr 7:31,409,015...31,469,741
Ensembl chr 7:31,408,814...31,464,943

Janus kinase 3

involved_in

(PMID:9498750)

PMID:9498750

NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805

LAG3

lymphocyte activating 3

acts_upstream_of_or_within
involved_in

(PMID:12209638), (PMID:30580966)

PMID:12209638 PMID:30580966

GO_REF:0000107

NCBI chr27:38,260,673...38,266,771
Ensembl chr27:38,260,674...38,265,819

LAPTM5

lysosomal protein transmembrane 5

involved_in

GO_REF:0000107

NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073

LAX1

lymphocyte transmembrane adaptor 1

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr38:429,062...438,069
Ensembl chr38:429,528...436,696

LOC100687459

GTPase IMAP family member 5

NCBI chr16:14,887,308...14,895,522

LOC607055

angiopoietin-related protein 5-like

involved_in

GO_REF:0000033

NCBI chr10:17,040,257...17,042,108

MIR181C

microRNA mir-181c

acts_upstream_of

(PMID:21112091)

PMID:21112091

NCBI chr20:48,593,343...48,593,403
Ensembl chr20:48,593,325...48,593,421

MIR27A

microRNA mir-27a

involved_in

(PMID:24725595)

PMID:24725595

NCBI chr20:48,620,556...48,620,615
Ensembl chr20:48,620,556...48,620,615

PAG1

phosphoprotein membrane anchor with glycosphingolipid microdomains 1

involved_in

Ensembl
GO_Central
InterPro

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr29:28,207,445...28,340,812
Ensembl chr29:28,211,031...28,263,322

PDCD1

programmed cell death 1

involved_in

(PMID:21276005), (PMID:38377992)

PMID:21276005 PMID:38377992

NCBI chr25:51,606,559...51,618,903
Ensembl chr25:51,608,173...51,618,723

PELI1

pellino E3 ubiquitin protein ligase 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:63,727,905...63,863,599
Ensembl chr10:63,729,604...63,743,303

PLA2G2D

phospholipase A2 group IID

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:78,739,826...78,745,839
Ensembl chr 2:78,739,769...78,745,920

PTPN22

protein tyrosine phosphatase non-receptor type 22

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858

SOCS6

suppressor of cytokine signaling 6

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:8,078,500...8,117,651
Ensembl chr 1:8,082,389...8,083,996

sialophorin

acts_upstream_of_or_within

(PMID:9645617)

PMID:9645617

NCBI chr 6:17,770,303...17,774,946

transforming growth factor beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885

TIGIT

T cell immunoreceptor with Ig and ITIM domains

involved_in
acts_upstream_of_or_within

InterPro
Ensembl
GO_Central

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr33:18,484,106...18,501,517
Ensembl chr33:18,485,955...18,499,440

TNFAIP8L2

TNF alpha induced protein 8 like 2

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr17:60,219,239...60,222,818
Ensembl chr17:60,221,592...60,222,146

UFL1

UFM1 specific ligase 1

involved_in

GO_REF:0000107

NCBI chr12:54,988,200...55,023,414
Ensembl chr12:54,988,264...55,021,626

VTCN1

V-set domain containing T cell activation inhibitor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:54,533,153...54,587,262
Ensembl chr17:54,536,026...54,587,110

negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HAVCR2

hepatitis A virus cellular receptor 2

involved_in

GO_REF:0000107

NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393

LGALS3

galectin 3

involved_in

(PMID:19706535)

PMID:19706535

NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705

negative regulation of T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:17163451)

PMID:17163451

NCBI chr 1:102,779,562...102,786,924

negative regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD74

CD74 molecule

acts_upstream_of_or_within

(PMID:7679955)

PMID:7679955

NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151

DTX1

deltex E3 ubiquitin ligase 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr26:10,469,850...10,502,682

IFNB1

interferon beta 1

involved_in

GO_REF:0000107

NCBI chr11:40,668,295...40,668,855
Ensembl chr11:40,668,295...40,668,855

IL29L

interleukin 29-like

involved_in

(PMID:19346497)

PMID:19346497

NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017

NRARP

NOTCH regulated ankyrin repeat protein

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:48,394,568...48,396,849
Ensembl chr 9:48,394,754...48,395,098

PRDX2

peroxiredoxin 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:49,352,271...49,356,755
Ensembl chr20:49,352,266...49,356,682

negative regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP4

bone morphogenetic protein 4

involved_in

GO_REF:0000107

NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557

FOXJ1

forkhead box J1

involved_in

GO_REF:0000107

NCBI chr 9:4,512,898...4,517,764
Ensembl chr 9:4,513,628...4,517,756

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

NFKBID

NFKB inhibitor delta

acts_upstream_of_or_within

(PMID:11931770)

PMID:11931770

NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325

RAG2

recombination activating 2

NCBI chr18:31,614,143...31,621,489
Ensembl chr18:31,618,481...31,620,064

sonic hedgehog signaling molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

ZC3H8

zinc finger CCCH-type containing 8

involved_in

GO_REF:0000107

NCBI chr17:36,584,828...36,621,194
Ensembl chr17:36,597,916...36,613,722

negative regulation of T cell homeostatic proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD24 molecule

acts_upstream_of_or_within

(PMID:16769998)

PMID:16769998

NCBI chr12:64,239,957...64,245,114

negative regulation of T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARG1

arginase 1

involved_in

(PMID:16709924)

PMID:16709924

NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305

B9 domain containing 2

acts_upstream_of_or_within

(PMID:17481928)

PMID:17481928

NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885

BTLA

B and T lymphocyte associated

acts_upstream_of_or_within
involved_in

(PMID:12796776)

MGI
Ensembl

PMID:12796776

GO_REF:0000107

NCBI chr33:16,978,173...17,006,837
Ensembl chr33:16,979,634...17,007,033

CD274 molecule

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522

CD276

CD276 molecule

acts_upstream_of_or_within

(PMID:12925852)

PMID:12925852

NCBI chr30:36,975,085...36,990,012
Ensembl chr30:36,975,085...36,988,924

CD37

CD37 molecule

acts_upstream_of_or_within

(PMID:20709950)

PMID:20709950

NCBI chr 1:107,130,553...107,136,602
Ensembl chr 1:107,128,996...107,136,081

CD80 molecule

involved_in

GO_REF:0000033

NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380

CD86

CD86 molecule

involved_in

GO_REF:0000033

NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087

CEA cell adhesion molecule 1

acts_upstream_of_or_within

(PMID:17081782)

PMID:17081782

NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830

CEBPB

CCAAT enhancer binding protein beta

involved_in

GO_REF:0000107

NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656

CLEC4G

C-type lectin domain family 4 member G

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:52,476,162...52,480,341
Ensembl chr20:52,476,200...52,479,930

CTLA4

cytotoxic T-lymphocyte associated protein 4

NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874

DLA-12

MHC class I DLA-12

involved_in

(PMID:20195504)

PMID:20195504

NCBI chr12:933,321...936,671
Ensembl chr12:932,613...987,561

DLA-DQB1

major histocompatibility complex, class II, DQ beta 1

NCBI chr12:2,305,307...2,307,711

MHC class II DLA DRB1 beta chain

involved_in

(PMID:15795121)

PMID:15795121

NCBI chr12:2,151,409...2,164,564

DLG1

discs large MAGUK scaffold protein 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr33:30,016,323...30,253,180
Ensembl chr33:30,016,600...30,253,547

DLG5

discs large MAGUK scaffold protein 5

involved_in

GO_REF:0000107

NCBI chr 4:27,687,223...27,780,007
Ensembl chr 4:27,687,287...27,806,722

FOXJ1

forkhead box J1

involved_in

GO_REF:0000107

NCBI chr 9:4,512,898...4,517,764
Ensembl chr 9:4,513,628...4,517,756

forkhead box P3

acts_upstream_of_or_within
involved_in

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

GLMN

glomulin, FKBP associated protein

involved_in

GO_REF:0000107

NCBI chr 6:56,631,186...56,678,397
Ensembl chr 6:56,644,456...56,678,399

GPNMB

glycoprotein nmb

involved_in

(PMID:19350579)

ParkinsonsUK-UCL

PMID:19350579

NCBI chr14:36,919,184...36,947,023
Ensembl chr14:36,919,296...36,946,643

HAVCR2

hepatitis A virus cellular receptor 2

involved_in

GO_REF:0000107

NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393

IDO1

indoleamine 2,3-dioxygenase 1

acts_upstream_of_or_within

(PMID:18077788)

PMID:18077788

NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048

IL20RB

interleukin 20 receptor subunit beta

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr23:33,384,057...33,421,619
Ensembl chr23:33,384,486...33,420,016

interleukin 2 receptor subunit alpha

acts_upstream_of_or_within

(PMID:12702495)

PMID:12702495

NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643

IL4I1

interleukin 4 induced 1

involved_in

GO_REF:0000107

NCBI chr 1:106,636,282...106,673,438
Ensembl chr 1:106,657,477...106,673,422

LOC482848

tumor necrosis factor receptor superfamily, member 21 pseudogene

involved_in

GO_REF:0000033

NCBI chr16:26,030,978...26,033,068

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:17163451)

PMID:17163451

NCBI chr 1:102,779,562...102,786,924

LOC490269

complement receptor type 2

involved_in

(PMID:16360013)

PMID:16360013

NCBI chr 7:6,456,238...6,480,672

MAD1L1

mitotic arrest deficient 1 like 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:14,889,126...15,236,194
Ensembl chr 6:14,882,875...15,236,192

MARCHF7

membrane associated ring-CH-type finger 7

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr36:5,481,449...5,533,139
Ensembl chr36:5,481,456...5,531,957

PAWR

pro-apoptotic WT1 regulator

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr15:22,114,014...22,159,287

programmed cell death 1 ligand 2

acts_upstream_of_or_within
involved_in

(PMID:11224527), (PMID:17016562)

PMID:11224527 PMID:17016562

GO_REF:0000033

NCBI chr 1:93,631,676...93,698,560
Ensembl chr 1:93,631,979...93,689,266

PDE5A

phosphodiesterase 5A

acts_upstream_of_or_within

(PMID:17101732)

PMID:17101732

NCBI chr32:38,272,573...38,407,517
Ensembl chr32:38,244,338...38,407,522

PELI1

pellino E3 ubiquitin protein ligase 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:63,727,905...63,863,599
Ensembl chr10:63,729,604...63,743,303

PLA2G2D

phospholipase A2 group IID

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:78,739,826...78,745,839
Ensembl chr 2:78,739,769...78,745,920

PLA2G2F

phospholipase A2 group IIF

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:78,714,251...78,724,257
Ensembl chr 2:78,716,228...78,723,984

PLA2G5

phospholipase A2 group V

involved_in

GO_REF:0000033

NCBI chr 2:78,762,851...78,781,642
Ensembl chr 2:78,762,852...78,781,983

PTEN

phosphatase and tensin homolog

acts_upstream_of_or_within

(PMID:16027169)

PMID:16027169

NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176

PTPN11

protein tyrosine phosphatase non-receptor type 11

involved_in

GO_REF:0000107

NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481

PTPN6

protein tyrosine phosphatase non-receptor type 6

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937

RIPOR2

RHO family interacting cell polarization regulator 2

involved_in

(PMID:27556504)

PMID:27556504

NCBI chr35:22,823,053...23,041,765
Ensembl chr35:22,824,106...23,041,743

SCGB1A1

secretoglobin family 1A member 1

acts_upstream_of_or_within

(PMID:15356574)

PMID:15356574

NCBI chr18:54,187,487...54,191,493
Ensembl chr18:54,187,487...54,191,482

SDC4

syndecan 4

involved_in

GO_REF:0000107

NCBI chr24:32,628,704...32,648,809
Ensembl chr24:32,630,437...32,649,114

surfactant protein D

NCBI chr 4:29,394,755...29,407,499
Ensembl chr 4:29,394,678...29,407,293

sonic hedgehog signaling molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

sialophorin

acts_upstream_of_or_within
involved_in

PMID:7566153 PMID:9645617 PMID:15117976 PMID:17638845

(PMID:15117976), (PMID:7566153), (PMID:9645617)
(PMID:17638845)

MGI
UniProt

NCBI chr 6:17,770,303...17,774,946

transforming growth factor beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885

TNF receptor superfamily member 14

involved_in

(PMID:15568026)

PMID:15568026

NCBI chr 5:57,386,190...57,416,864
Ensembl chr 5:57,411,529...57,416,512

TNFRSF21

TNF receptor superfamily member 21

involved_in

GO_REF:0000033

NCBI chr12:15,343,953...15,408,230

TSC2

TSC complex subunit 2

acts_upstream_of_or_within

(PMID:16027169)

PMID:16027169

NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960

TSPAN32

tetraspanin 32

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr18:46,422,499...46,438,512
Ensembl chr18:46,422,259...46,437,272

VSIG4

V-set and immunoglobulin domain containing 4

involved_in
acts_upstream_of_or_within

IEA
IBA
ISO

(PMID:17016562)

InterPro
GO_Central
MGI

PMID:17016562

GO_REF:0000002 GO_REF:0000033

NCBI chr X:50,839,979...50,881,684
Ensembl chr X:50,803,330...50,881,618

VTCN1

V-set domain containing T cell activation inhibitor 1

involved_in

GO_REF:0000107

NCBI chr17:54,533,153...54,587,262
Ensembl chr17:54,536,026...54,587,110

ZC3H12D

zinc finger CCCH-type containing 12D

acts_upstream_of_or_within

(PMID:24415781)

PMID:24415781

NCBI chr 1:40,249,856...40,279,344
Ensembl chr 1:40,259,705...40,279,888

negative regulation of T-helper 1 cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

lymphotactin

involved_in

(PMID:10887101)

PMID:10887101

NCBI chr 7:29,986,433...29,991,096

negative regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

GO_REF:0000107

NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975

IL4R

interleukin 4 receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291

Janus kinase 3

involved_in

(PMID:16020505)

PMID:16020505

NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805

TNF superfamily member 4

involved_in

(PMID:9670042)

PMID:9670042

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

negative regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

GO_REF:0000107

NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975

forkhead box P3

involved_in

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

IL2

interleukin 2

involved_in

GO_REF:0000107

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

interleukin 4

acts_upstream_of_or_within

(PMID:18792410)

PMID:18792410

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

RC3H1

ring finger and CCCH-type domains 1

involved_in

GO_REF:0000107

NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174

RC3H2

ring finger and CCCH-type domains 2

involved_in

GO_REF:0000107

NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341

SMAD7

SMAD family member 7

involved_in

GO_REF:0000107

NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749

TBX21

T-box transcription factor 21

involved_in

GO_REF:0000107

NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261

zinc finger and BTB domain containing 7B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

ZC3H12A

zinc finger CCCH-type containing 12A

involved_in

GO_REF:0000107

NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371

negative regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD69

CD69 molecule

involved_in

GO_REF:0000107

NCBI chr27:36,197,202...36,205,045
Ensembl chr27:36,197,175...36,204,597

Janus kinase 3

involved_in

GO_REF:0000107

NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805

LGALS1

galectin 1

involved_in

(PMID:24752896)

PMID:24752896

NCBI chr10:26,932,351...26,935,580
Ensembl chr10:26,932,301...26,935,646

LOXL3

lysyl oxidase like 3

involved_in

GO_REF:0000107

NCBI chr17:48,590,996...48,610,264
Ensembl chr17:48,591,768...48,610,392

signal transducer and activator of transcription 5A

involved_in

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

TBX21

T-box transcription factor 21

involved_in

GO_REF:0000107

NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261

TNFSF18

TNF superfamily member 18

involved_in

(PMID:24107315)

PMID:24107315

NCBI chr 7:25,983,064...25,994,605
Ensembl chr 7:25,963,719...25,992,801

negative regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA1

annexin A1

involved_in

GO_REF:0000107

NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011

ASCL2

achaete-scute family bHLH transcription factor 2

involved_in

GO_REF:0000107

NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975

BCL6

BCL6 transcription repressor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704

HLX

H2.0 like homeobox

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152

LOC111089966

zinc finger protein 271

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:54,714,912...54,727,638

RTP2

receptor transporter protein 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428

SOCS5

suppressor of cytokine signaling 5

involved_in

GO_REF:0000107

NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452

negative regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RC3H1

ring finger and CCCH-type domains 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174

neural crest cell delamination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SPECC1L

sperm antigen with calponin homology and coiled-coil domains 1 like

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr26:27,994,278...28,127,383
Ensembl chr26:28,025,987...28,125,695

neuroblast delamination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKNA

AT-hook transcription factor

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr11:68,561,522...68,600,724
Ensembl chr11:68,562,145...68,598,557

positive regulation of activated T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGER

advanced glycosylation end-product specific receptor

involved_in

GO_REF:0000107

NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129

CD24 molecule

involved_in

(PMID:11272271)

PMID:11272271

NCBI chr12:64,239,957...64,245,114

CD86 molecule

NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087

erythropoietin

NCBI chr 6:8,994,211...8,995,954
Ensembl chr 6:8,994,211...8,996,144

FADD

Fas associated via death domain

involved_in

GO_REF:0000107

NCBI chr18:48,087,447...48,094,497

GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr28:23,261,673...23,323,985
Ensembl chr28:23,258,428...23,298,017

HHLA2

HHLA2 member of B7 family

involved_in

(PMID:23784006)

NCBI chr33:13,606,724...13,622,678

HMGB1

high mobility group box 1

involved_in

GO_REF:0000107

NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165

IGF1

insulin like growth factor 1

involved_in

GO_REF:0000107

NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794

IGF2

insulin like growth factor 2

involved_in

GO_REF:0000033

NCBI chr18:46,294,036...46,311,982
Ensembl chr18:46,294,019...46,311,982

IGFBP2

insulin like growth factor binding protein 2

involved_in

GO_REF:0000107

NCBI chr37:23,553,227...23,569,321
Ensembl chr37:23,559,501...23,569,312

interleukin 12B

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228

IL12RB1

interleukin 12 receptor subunit beta 1

involved_in

GO_REF:0000107

NCBI chr20:44,885,410...44,908,139
Ensembl chr20:44,885,337...44,904,538

IL18

interleukin 18

involved_in

(PMID:8766574)

PMID:8766574

GO_REF:0000107

NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348

IL2

interleukin 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

interleukin 23 subunit alpha

involved_in

GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

interleukin 2 receptor subunit alpha

acts_upstream_of_or_within

(PMID:7584142)

PMID:7584142

NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643

interleukin 4

acts_upstream_of_or_within

(PMID:10485657), (PMID:9841920)

PMID:9841920 PMID:10485657

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

Janus kinase 3

NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805

LOC100684393

small nuclear ribonucleoprotein-associated proteins B and B'

involved_in

(PMID:23784006)

NCBI chr20:55,349,126...55,350,721

MIR21

microRNA mir-21

involved_in

(PMID:22387553)

NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624

MIR30B

microRNA mir-30b

involved_in

(PMID:22387553)

NCBI chr13:30,906,038...30,906,097
Ensembl chr13:30,906,038...30,906,097

PPP3CA

protein phosphatase 3 catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr32:22,688,141...22,996,693
Ensembl chr32:22,688,143...22,996,688

PYCARD

PYD and CARD domain containing

involved_in

GO_REF:0000107

NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240

RPS3

ribosomal protein S3

involved_in

(PMID:18045535)

CAFA

PMID:18045535

NCBI chr21:23,180,515...23,187,034
Ensembl chr21:23,180,515...23,187,034

SLAMF1

signaling lymphocytic activation molecule family member 1

involved_in

GO_REF:0000107

NCBI chr38:21,653,801...21,685,408
Ensembl chr38:21,653,487...21,685,408

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

STAT5B

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485

TNF superfamily member 4

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

TNFSF9

TNF superfamily member 9

NCBI chr20:53,680,882...53,682,521
Ensembl chr20:53,679,880...53,682,706

positive regulation of alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

GLI3

GLI family zinc finger 3

involved_in

GO_REF:0000107

NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

ITPKB

inositol-trisphosphate 3-kinase B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:38,253,257...38,346,400
Ensembl chr 7:38,253,407...38,343,345

NKAP

NFKB activating protein

involved_in

GO_REF:0000107

NCBI chr X:91,922,326...91,956,566
Ensembl chr X:91,923,550...91,956,414

PNP

purine nucleoside phosphorylase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr15:17,808,454...17,815,987
Ensembl chr15:17,808,461...17,815,676

RHOA

ras homolog family member A

involved_in

GO_REF:0000107

NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

spleen associated tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

ZAP70

zeta chain of T cell receptor associated protein kinase 70

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071

positive regulation of alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BLM

BLM RecQ like helicase

acts_upstream_of_or_within

(PMID:17210642)

PMID:17210642

NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146

CCR2

C-C motif chemokine receptor 2

involved_in

GO_REF:0000107

NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698

CD24 molecule

acts_upstream_of_or_within

(PMID:1346270), (PMID:9368605)
(PMID:1385153), (PMID:7908303)
(PMID:9368605)

PMID:1346270 PMID:1385153 PMID:7908303 PMID:9368605

NCBI chr12:64,239,957...64,245,114

CD80 molecule

acts_upstream_of_or_within

(PMID:1385153)

PMID:1385153

NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124

spleen associated tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

TNF superfamily member 4

involved_in

(PMID:16670306)

PMID:16670306

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

ZAP70

zeta chain of T cell receptor associated protein kinase 70

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071

positive regulation of calcium-dependent cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KIFAP3

kinesin associated protein 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:28,581,855...28,739,327
Ensembl chr 7:28,593,425...28,739,272

positive regulation of calcium-independent cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CX3CL1

C-X3-C motif chemokine ligand 1

involved_in

GO_REF:0000107

NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095

positive regulation of CD4-positive, alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD55

CD55 molecule

involved_in

(PMID:16818763)

PMID:16818763

NCBI chr 7:6,361,037...6,396,063
Ensembl chr 7:6,360,964...6,386,226

MHC class II DR alpha chain

involved_in

GO_REF:0000107

NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975

MHC class II DLA DRB1 beta chain

involved_in

(PMID:15265931)

PMID:15265931

NCBI chr12:2,151,409...2,164,564

positive regulation of CD4-positive, alpha-beta T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TNF superfamily member 4

involved_in

(PMID:20639485)

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

positive regulation of CD4-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD83

CD83 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr35:13,489,046...13,507,897
Ensembl chr35:13,489,000...13,507,068

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

SASH3

SAM and SH3 domain containing 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:100,989,605...101,003,162
Ensembl chr X:100,989,685...101,001,885

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:24880459)

PMID:24880459

NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557

TNF superfamily member 4

involved_in

(PMID:20639485)

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

zinc finger and BTB domain containing 7B

involved_in

GO_REF:0000107

NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436

positive regulation of CD4-positive, alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CARD11

caspase recruitment domain family member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094

CD24 molecule

acts_upstream_of_or_within

(PMID:15314074)
(PMID:8125140)

PMID:8125140 PMID:15314074

NCBI chr12:64,239,957...64,245,114

CD28

CD28 molecule

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854

CD3 epsilon subunit of T-cell receptor complex

acts_upstream_of_or_within

(PMID:11894097), (PMID:14973438), (PMID:8125140)

PMID:8125140 PMID:11894097 PMID:14973438

NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260

CD55

CD55 molecule

involved_in

(PMID:16818763)

PMID:16818763

NCBI chr 7:6,361,037...6,396,063
Ensembl chr 7:6,360,964...6,386,226

CD81

CD81 molecule

involved_in

(PMID:22307619)

PMID:22307619

NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868

galectin 9

involved_in

(PMID:16116184)

PMID:16116184

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

lymphotactin

involved_in

(PMID:9973465)

PMID:9973465

NCBI chr 7:29,986,433...29,991,096

LOC606863

immunity-related GTPase family M protein-like

involved_in

(PMID:18806793)

PMID:18806793

NCBI chr11:506,981...523,338
Ensembl chr11:509,636...510,829

protein kinase C theta

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337

RIPK2

receptor interacting serine/threonine kinase 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333

TGFBR2

transforming growth factor beta receptor 2

involved_in

GO_REF:0000107

NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MHC class II DR alpha chain

involved_in

GO_REF:0000107

NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975

MHC class II DLA DRB1 beta chain

involved_in

(PMID:28467828)

PMID:28467828

NCBI chr12:2,151,409...2,164,564

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

IL2RG

interleukin 2 receptor subunit gamma

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:55,480,846...55,488,485
Ensembl chr X:55,481,092...55,484,751

KLHL25

kelch like family member 25

involved_in

(PMID:34491895)

PMID:34491895

NCBI chr 3:49,339,576...49,375,473
Ensembl chr 3:49,348,982...49,351,663

LOC100687459

GTPase IMAP family member 5

NCBI chr16:14,887,308...14,895,522

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IFNG

interferon gamma

involved_in

GO_REF:0000107

NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698

galectin 9

involved_in

(PMID:20209097)

PMID:20209097

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

positive regulation of CD8-positive, alpha-beta T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DLA-12

MHC class I DLA-12

involved_in

(PMID:28676677)

PMID:28676677

NCBI chr12:933,321...936,671
Ensembl chr12:932,613...987,561

positive regulation of CD8-positive, alpha-beta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CBFB

core-binding factor subunit beta

involved_in

(PMID:18258917)

NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:18420485)

PMID:18420485

NCBI chr 1:102,779,562...102,786,924

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

RUNX1

RUNX family transcription factor 1

involved_in

(PMID:18258917)

NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839

RUNX3

RUNX family transcription factor 3

involved_in

(PMID:18258917)

positive regulation of CD8-positive, alpha-beta T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD244

CD244 molecule

involved_in

(PMID:11739483)

PMID:11739483

NCBI chr38:21,495,649...21,522,656
Ensembl chr38:21,495,720...21,517,043

DLA-12

MHC class I DLA-12

involved_in

(PMID:25631937)

PMID:25631937

NCBI chr12:933,321...936,671
Ensembl chr12:932,613...987,561

lymphotactin

involved_in

(PMID:10887101)

PMID:10887101

NCBI chr 7:29,986,433...29,991,096

PTPN22

protein tyrosine phosphatase non-receptor type 22

involved_in

GO_REF:0000107

NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858

positive regulation of cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AFDN

afadin, adherens junction formation factor

involved_in

(PMID:25893857)

PMID:25893857

NCBI chr 1:55,435,451...55,535,534
Ensembl chr 1:55,435,472...55,535,543

CCL2

C-C motif chemokine ligand 2

leukocyte-endothelium

RGD

PMID:10225970

RGD:8549768

NCBI chr 9:39,008,187...39,009,932

CCR5

C-C motif chemokine receptor 5

NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952

CD24 molecule

acts_upstream_of_or_within

(PMID:7669058), (PMID:8557754), (PMID:9177270)

PMID:7669058 PMID:8557754 PMID:9177270

NCBI chr12:64,239,957...64,245,114

CD47

CD47 molecule

involved_in

InterPro
GO_Central
Ensembl

GO_REF:0000002 GO_REF:0000033 GO_REF:0000107

NCBI chr33:13,315,984...13,362,971
Ensembl chr33:13,319,266...13,363,580

CDH1

cadherin 1

acts_upstream_of_or_within

(PMID:2519616)

PMID:2519616

NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878

CITED2

Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

involved_in

GO_REF:0000107

NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995

FSTL3

follistatin like 3

involved_in

GO_REF:0000107

NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172

fucosyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303

ITGA6

integrin subunit alpha 6

acts_upstream_of_or_within

(PMID:7669058)

PMID:7669058

NCBI chr36:16,777,363...16,858,725
Ensembl chr36:16,776,863...16,855,449

ITGAL

integrin subunit alpha L

acts_upstream_of_or_within

(PMID:1346270)

PMID:1346270

NCBI chr 6:17,605,611...17,645,134
Ensembl chr 6:17,605,760...17,644,986

KIF26B

kinesin family member 26B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:36,087,483...36,529,334
Ensembl chr 7:36,088,050...36,522,653

L1CAM

L1 cell adhesion molecule

acts_upstream_of_or_within

(PMID:7669058)

PMID:7669058

NCBI chr X:121,708,695...121,722,819
Ensembl chr X:121,708,894...121,733,365

LOC609523

signal-regulatory protein beta-1

involved_in

(PMID:15383453)

PMID:15383453

NCBI chr24:19,524,314...19,555,872

MAGI1

membrane associated guanylate kinase, WW and PDZ domain containing 1

involved_in

GO_REF:0000107

NCBI chr20:25,314,597...25,952,256
Ensembl chr20:25,314,923...25,949,921

MEGF10

multiple EGF like domains 10

involved_in

GO_REF:0000107

NCBI chr11:16,359,648...16,574,882
Ensembl chr11:16,378,669...16,617,335

MEX3B

mex-3 RNA binding family member B

acts_upstream_of_or_within

(PMID:24803656)

PMID:24803656

NCBI chr 3:55,911,159...55,914,188
Ensembl chr 3:55,911,526...55,914,118

MYO10

myosin X

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 4:86,701,907...86,792,432
Ensembl chr 4:86,596,225...86,792,257

NODAL

nodal growth differentiation factor

involved_in

(PMID:21116837)

PMID:21116837

NCBI chr 4:21,366,828...21,374,623
Ensembl chr 4:21,367,583...21,375,151

phosphodiesterase 4D

NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912

PKP1

plakophilin 1

involved_in

GO_REF:0000107

NCBI chr 7:1,921,143...1,966,910
Ensembl chr 7:1,921,143...1,967,703

PKP3

plakophilin 3

involved_in

GO_REF:0000107

NCBI chr18:25,540,073...25,547,667
Ensembl chr18:25,540,073...25,547,667

RAP1GAP

RAP1 GTPase activating protein

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:77,509,592...77,554,620
Ensembl chr 2:77,527,914...77,544,205

RNASE10

ribonuclease A family member 10 (inactive)

involved_in

(PMID:22750516)

PMID:22750516

NCBI chr15:17,845,687...17,908,672
Ensembl chr15:17,840,091...17,844,406
Ensembl chr15:17,840,091...17,844,406

SOX2

SRY-box transcription factor 2

NCBI chr34:14,853,000...14,855,153

TBX18

T-box transcription factor 18

acts_upstream_of_or_within

(PMID:18353863)

PMID:18353863

NCBI chr12:44,901,076...44,929,730
Ensembl chr12:44,873,119...44,929,205

Wnt family member 5A

NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673

YWHAG

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

involved_in

GO_REF:0000107

NCBI chr 6:7,504,834...7,548,097
Ensembl chr 6:7,507,608...7,532,409

positive regulation of cell-cell adhesion mediated by cadherin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADAM19

ADAM metallopeptidase domain 19

involved_in

(PMID:19727588)

PMID:19727588

NCBI chr 4:52,650,077...52,733,299
Ensembl chr 4:52,650,162...52,729,843

AFDN

afadin, adherens junction formation factor

involved_in

(PMID:16882694)

PMID:16882694

NCBI chr 1:55,435,451...55,535,534
Ensembl chr 1:55,435,472...55,535,543

DENND6A

DENN domain containing 6A

involved_in

GO_REF:0000107

NCBI chr20:32,780,529...32,830,388
Ensembl chr20:32,780,579...32,830,478

FLOT1

flotillin 1

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr12:517,941...528,677
Ensembl chr12:516,032...528,637

PTPRU

protein tyrosine phosphatase receptor type U

involved_in

GO_REF:0000107

NCBI chr 2:71,284,979...71,363,253
Ensembl chr 2:71,285,851...71,363,691

SMAD7

SMAD family member 7

involved_in

GO_REF:0000107

NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749

TJP1

tight junction protein 1

involved_in

(PMID:25753039)

PMID:25753039

NCBI chr 3:38,997,122...39,076,617
Ensembl chr 3:38,997,076...39,241,574

WNT3A

Wnt family member 3A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412

WNT5A

Wnt family member 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673

positive regulation of cell-cell adhesion mediated by integrin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCL5

C-C motif chemokine ligand 5

involved_in

(PMID:8558019)

PMID:8558019

NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852

CD24 molecule

acts_upstream_of_or_within

(PMID:7534304)

PMID:7534304

NCBI chr12:64,239,957...64,245,114

CD3 epsilon subunit of T-cell receptor complex

involved_in

(PMID:12652296)

PMID:12652296

NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260

CXCL13

C-X-C motif chemokine ligand 13

involved_in

(PMID:15972452)

PMID:15972452

NCBI chr32:2,047,277...2,053,277
Ensembl chr32:2,047,315...2,052,833

PIEZO1

piezo type mechanosensitive ion channel component 1

involved_in

GO_REF:0000107

NCBI chr 5:64,584,153...64,640,423
Ensembl chr 5:64,570,035...64,640,375

PODXL

podocalyxin like

involved_in

ISS
IBA

UniProt
GO_Central

GO_REF:0000024 GO_REF:0000033

NCBI chr14:5,614,006...5,625,360
Ensembl chr14:5,590,478...5,625,360

SKAP1

src kinase associated phosphoprotein 1

involved_in

GO_REF:0000107

NCBI chr 9:24,412,820...24,700,579
Ensembl chr 9:24,412,820...24,700,734

positive regulation of cytotoxic T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SART1

spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP

involved_in

GO_REF:0000107

NCBI chr18:51,297,419...51,313,804
Ensembl chr18:51,297,419...51,313,793

TNFSF9

TNF superfamily member 9

NCBI chr20:53,680,882...53,682,521
Ensembl chr20:53,679,880...53,682,706

positive regulation of erythrocyte aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

galectin 1

NCBI chr10:26,932,351...26,935,580
Ensembl chr10:26,932,301...26,935,646

positive regulation of establishment of T cell polarity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABL1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307

ABL2

ABL proto-oncogene 2, non-receptor tyrosine kinase

involved_in

(PMID:22810897)

PMID:22810897

NCBI chr 7:20,696,659...20,735,362
Ensembl chr 7:20,700,144...20,727,410

DOCK8

dedicator of cytokinesis 8

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr 1:89,152,456...89,379,203
Ensembl chr 1:89,150,856...89,378,013

FLOT2

flotillin 2

involved_in

GO_REF:0000107

NCBI chr 9:43,050,929...43,066,886
Ensembl chr 9:43,052,114...43,071,742

positive regulation of gamma-delta T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LCK proto-oncogene, Src family tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567

LEF1

lymphoid enhancer binding factor 1

involved_in

GO_REF:0000107

NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019

LOC100687459

GTPase IMAP family member 5

NCBI chr16:14,887,308...14,895,522

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124

SOX13

SRY-box transcription factor 13

involved_in

GO_REF:0000107

NCBI chr38:702,974...721,340
Ensembl chr38:523,481...720,195

SOX4

SRY-box transcription factor 4

involved_in

GO_REF:0000107

NCBI chr35:20,098,783...20,101,357
Ensembl chr35:20,099,773...20,101,154

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

STAT5B

signal transducer and activator of transcription 5B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485

spleen associated tyrosine kinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

positive regulation of heterotypic cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGER

advanced glycosylation end-product specific receptor

involved_in

GO_REF:0000107

NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129

ALOX15

arachidonate 15-lipoxygenase

NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119

BMP7

bone morphogenetic protein 7

involved_in

GO_REF:0000107

NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653

CD44 molecule

involved_in

GO_REF:0000107

NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107

FGA

fibrinogen alpha chain

involved_in

GO_REF:0000033

NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975

FGB

fibrinogen beta chain

involved_in

GO_REF:0000107

NCBI chr15:52,220,690...52,228,526
Ensembl chr15:52,220,611...52,228,250

FGG

fibrinogen gamma chain

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr15:52,261,215...52,270,077
Ensembl chr15:52,261,217...52,269,964

FLOT1

flotillin 1

involved_in

GO_REF:0000107

NCBI chr12:517,941...528,677
Ensembl chr12:516,032...528,637

GCNT2

glucosaminyl (N-acetyl) transferase 2 (I blood group)

involved_in

GO_REF:0000107

NCBI chr35:10,304,741...10,387,746
Ensembl chr35:10,305,350...10,385,672

IL1B

interleukin 1 beta

involved_in

GO_REF:0000107

NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458

LCK proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567

SKAP1

src kinase associated phosphoprotein 1

involved_in

GO_REF:0000107

NCBI chr 9:24,412,820...24,700,579
Ensembl chr 9:24,412,820...24,700,734

TNF

tumor necrosis factor

involved_in

GO_REF:0000107

NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425

positive regulation of homophilic cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CEA cell adhesion molecule 1

involved_in

PMID:8831574

NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830

PTPN23

protein tyrosine phosphatase non-receptor type 23

involved_in

GO_REF:0000107

NCBI chr20:41,485,959...41,511,250
Ensembl chr20:41,485,195...41,587,003

positive regulation of homotypic cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ankyrin 3

NCBI chr 4:12,166,275...12,827,175
Ensembl chr 4:12,167,550...12,827,037

CCL5

C-C motif chemokine ligand 5

involved_in

(PMID:10488085)

PMID:10488085

NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852

CTNNB1

catenin beta 1

involved_in

GO_REF:0000107

NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927

JAK1

Janus kinase 1

involved_in

GO_REF:0000107

NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571

PLAUR

plasminogen activator, urokinase receptor

involved_in

(PMID:21679692)

PMID:21679692

NCBI chr 1:111,476,804...111,490,876
Ensembl chr 1:111,476,893...111,490,880

PLPP3

phospholipid phosphatase 3

involved_in

GO_REF:0000107

NCBI chr 5:52,924,443...53,006,298
Ensembl chr 5:52,923,833...53,005,493

TNFSF11

TNF superfamily member 11

involved_in

GO_REF:0000107

NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645

positive regulation of immature T cell proliferation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BLM

BLM RecQ like helicase

acts_upstream_of_or_within

(PMID:17210642)

PMID:17210642

NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146

BMI1

BMI1 proto-oncogene, polycomb ring finger

involved_in

GO_REF:0000107

NCBI chr 2:10,818,232...10,828,473
Ensembl chr 2:10,818,232...10,833,613

forkhead box P3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

IL1A

interleukin 1 alpha

involved_in

GO_REF:0000033

NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435

IL1B

interleukin 1 beta

involved_in

RGD
GO_Central

PMID:8590311

GO_REF:0000033 RGD:7401228

NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458

RIPK2

receptor interacting serine/threonine kinase 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

positive regulation of leukocyte adhesion to arterial endothelial cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ALOX5

arachidonate 5-lipoxygenase

involved_in

GO_REF:0000107

NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609

MIR92A-1

microRNA mir-92a-1

involved_in

(PMID:22267480)

PMID:22267480

NCBI chr22:42,478,714...42,478,772

MIR92A-2

microRNA mir-92a-2

involved_in

(PMID:22267480)

PMID:22267480

NCBI chr X:104,895,826...104,895,886
Ensembl chr X:104,895,826...104,895,886

selectin L

NCBI chr 7:28,906,752...28,927,959
Ensembl chr 7:28,906,809...29,094,008

TNF

tumor necrosis factor

involved_in

GO_REF:0000107

NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425

positive regulation of leukocyte adhesion to vascular endothelial cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ETS1

ETS proto-oncogene 1, transcription factor

involved_in

(PMID:21310411)

PMID:21310411

NCBI chr 5:6,059,023...6,189,516
Ensembl chr 5:6,058,935...6,186,232

fucosyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303

ICAM1

intercellular adhesion molecule 1

NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914

interleukin 6

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519

IRAK1

interleukin 1 receptor associated kinase 1

involved_in

GO_REF:0000107

NCBI chr X:121,853,340...121,862,582
Ensembl chr X:121,819,432...121,862,576

ITGB2

integrin subunit beta 2

involved_in

(PMID:24458438)

PMID:24458438

NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018

LOC491316

midkine

involved_in

(PMID:24458438)

PMID:24458438

NCBI chr 9:55,100,491...55,101,081

MIR21

microRNA mir-21

involved_in

(PMID:21636785)

PMID:21636785

NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624

MIR92A-1

microRNA mir-92a-1

involved_in

(PMID:24255059)
(PMID:23897866)

PMID:23897866 PMID:24255059

NCBI chr22:42,478,714...42,478,772

MIR92A-2

microRNA mir-92a-2

involved_in

(PMID:23897866)
(PMID:24255059)

PMID:23897866 PMID:24255059

NCBI chr X:104,895,826...104,895,886
Ensembl chr X:104,895,826...104,895,886

NFAT5

nuclear factor of activated T cells 5

involved_in

GO_REF:0000107

NCBI chr 5:79,995,292...80,115,116
Ensembl chr 5:80,003,587...80,115,096

RELA

RELA proto-oncogene, NF-kB subunit

involved_in

GO_REF:0000107

NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875

RHOA

ras homolog family member A

involved_in

GO_REF:0000107

NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215

TNF

tumor necrosis factor

involved_in

GO_REF:0000107

NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425

TRAF6

TNF receptor associated factor 6

involved_in

GO_REF:0000107

NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641

positive regulation of leukocyte cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ITGA4

integrin subunit alpha 4

NCBI chr36:24,670,464...24,686,719
Ensembl chr36:24,653,408...24,729,057

LCK proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567

MDK

midkine

involved_in

(PMID:24458438)

platelet activating factor receptor

NCBI chr 2:72,225,386...72,256,353
Ensembl chr 2:72,225,386...72,256,352

SKAP1

src kinase associated phosphoprotein 1

involved_in

GO_REF:0000107

NCBI chr 9:24,412,820...24,700,579
Ensembl chr 9:24,412,820...24,700,734

positive regulation of leukocyte tethering or rolling

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

calpain 1

NCBI chr18:51,983,266...52,010,831
Ensembl chr18:51,983,824...52,010,757

CCR2

C-C motif chemokine receptor 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698

CHST2

carbohydrate sulfotransferase 2

involved_in

GO_REF:0000107

NCBI chr23:38,695,627...38,701,216

CHST4

carbohydrate sulfotransferase 4

involved_in

(PMID:16227985)

PMID:16227985

NCBI chr 5:77,322,779...77,341,017
Ensembl chr 5:77,331,342...77,340,057

ELANE

elastase, neutrophil expressed

NCBI chr20:57,789,044...57,790,932
Ensembl chr20:57,788,062...57,790,932

fucosyltransferase 4

involved_in

(PMID:10894166), (PMID:11485743)

PMID:10894166 PMID:11485743

NCBI chr21:6,386,665...6,390,109
Ensembl chr21:6,389,021...6,390,793

fucosyltransferase 4

involved_in

GO_REF:0000107

fucosyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303

GCNT1

glucosaminyl (N-acetyl) transferase 1

involved_in

GO_REF:0000107

NCBI chr 1:81,985,519...82,017,420

GP1BA

glycoprotein Ib platelet subunit alpha

NCBI chr 5:31,681,605...31,683,261

ITGA4

integrin subunit alpha 4

NCBI chr36:24,670,464...24,686,719
Ensembl chr36:24,653,408...24,729,057

PAWR

pro-apoptotic WT1 regulator

NCBI chr15:22,114,014...22,159,287

PTAFR

platelet activating factor receptor

NCBI chr 2:72,225,386...72,256,353
Ensembl chr 2:72,225,386...72,256,352

SELE

selectin E

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr 7:28,888,503...28,898,787
Ensembl chr 7:28,888,197...28,898,786

SELP

selectin P

involved_in

GO_REF:0000107

NCBI chr 7:28,956,428...28,997,266
Ensembl chr 7:28,958,486...28,996,313

ST3GAL4

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

involved_in

GO_REF:0000107

NCBI chr 5:8,132,663...8,160,008
Ensembl chr 5:8,133,085...8,141,254

positive regulation of memory T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYRIB

CYFIP related Rac1 interactor B

involved_in

GO_REF:0000107

NCBI chr13:26,942,036...27,056,547
Ensembl chr13:26,942,229...27,003,644

TNF superfamily member 4

involved_in

(PMID:12496423)

PMID:12496423

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

positive regulation of memory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MHC class II DR alpha chain

involved_in

GO_REF:0000107

NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975

MHC class II DLA DRB1 beta chain

involved_in

(PMID:27591323)

PMID:27591323

NCBI chr12:2,151,409...2,164,564

interleukin 23 subunit alpha

involved_in

GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

LOC609365

CD46 molecule, complement regulatory protein-like

involved_in

(PMID:12540904)

PMID:12540904

NCBI chr 7:6,602,762...6,646,561

PCK1

phosphoenolpyruvate carboxykinase 1

involved_in

GO_REF:0000107

NCBI chr24:42,538,858...42,544,200
Ensembl chr24:42,538,882...42,544,198

TNF superfamily member 4

involved_in

(PMID:18713990)

PMID:18713990

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

positive regulation of monocyte aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD44 molecule

involved_in

GO_REF:0000107

NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107

HAS2

hyaluronan synthase 2

involved_in

GO_REF:0000107

NCBI chr13:20,310,946...20,342,647
Ensembl chr13:20,309,872...20,341,636

NR4A3

nuclear receptor subfamily 4 group A member 3

involved_in

GO_REF:0000107

NCBI chr11:56,806,506...56,846,997
Ensembl chr11:56,812,804...56,847,689

positive regulation of NK T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD1D

CD1d molecule

acts_upstream_of_or_within

(PMID:10201995), (PMID:11754812), (PMID:7538697)

PMID:7538697 PMID:10201995 PMID:11754812

NCBI chr38:23,489,169...23,491,712

IL12A

interleukin 12A

involved_in

GO_REF:0000107

NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550

interleukin 12B

involved_in

GO_REF:0000107

NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228

interleukin 23 subunit alpha

involved_in

GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

positive regulation of NK T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AP3B1

adaptor related protein complex 3 subunit beta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 3:28,481,974...28,748,095
Ensembl chr 3:28,481,038...28,751,258

AP3D1

adaptor related protein complex 3 subunit delta 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:56,893,479...56,932,460
Ensembl chr20:56,893,535...56,931,830

CD1D

CD1d molecule

acts_upstream_of_or_within

(PMID:9133426)
(PMID:10201995)

PMID:9133426 PMID:10201995

NCBI chr38:23,489,169...23,491,712

TGFBR2

transforming growth factor beta receptor 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636

ZBTB16

zinc finger and BTB domain containing 16

involved_in

GO_REF:0000107

NCBI chr 5:19,082,594...19,284,360
Ensembl chr 5:19,087,154...19,267,628

positive regulation of NK T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

interleukin 12B

involved_in

GO_REF:0000107

NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228

IL18

interleukin 18

involved_in

GO_REF:0000107

NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348

interleukin 23 subunit alpha

involved_in

GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

Janus kinase 2

involved_in

GO_REF:0000107

NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997

RASAL3

RAS protein activator like 3

involved_in

GO_REF:0000107

NCBI chr20:46,733,072...46,743,657
Ensembl chr20:46,732,952...46,743,924

TYK2

tyrosine kinase 2

involved_in

GO_REF:0000107

NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216

positive regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CTSG

cathepsin G

involved_in

GO_REF:0000107

NCBI chr 8:4,483,327...4,485,933
Ensembl chr 8:4,470,577...4,512,628

EMILIN2

elastin microfibril interfacer 2

involved_in

GO_REF:0000107

NCBI chr 7:69,521,430...69,580,963

F11R

F11 receptor

involved_in

GO_REF:0000107

NCBI chr38:21,433,819...21,456,722
Ensembl chr38:21,451,952...21,454,959

HTR2A

5-hydroxytryptamine receptor 2A

NCBI chr22:4,453,715...4,510,934
Ensembl chr22:4,453,715...4,511,037

interleukin 6

acts_upstream_of

GO_REF:0000107

NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519

IL6R

interleukin 6 receptor

acts_upstream_of

(PMID:31145836)

PMID:31145836

NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090

Janus kinase 2

acts_upstream_of

GO_REF:0000107

NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997

MFSD2B

MFSD2 lysolipid transporter B, sphingolipid

involved_in

(PMID:33863882)

PMID:33863882

NCBI chr17:18,496,559...18,506,472
Ensembl chr17:18,408,251...18,505,676

MMRN1

multimerin 1

involved_in

GO_REF:0000107

NCBI chr32:13,111,043...13,184,681
Ensembl chr32:13,110,969...13,184,649

PDPN

podoplanin

involved_in

ISS
IBA

UniProt
GO_Central

GO_REF:0000024 GO_REF:0000033

NCBI chr 2:83,552,735...83,581,375
Ensembl chr 2:83,552,830...83,581,375

positive regulation of pro-T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ZBTB1

zinc finger and BTB domain containing 1

involved_in

GO_REF:0000107

NCBI chr 8:38,933,721...38,959,306
Ensembl chr 8:38,933,805...38,959,306

positive regulation of regulatory T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AMBRA1

autophagy and beclin 1 regulator 1

involved_in

GO_REF:0000107

NCBI chr18:42,903,815...43,073,918
Ensembl chr18:42,932,513...43,072,827

B9 domain containing 2

involved_in

(PMID:25065622)

NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885

BCL6

BCL6 transcription repressor

involved_in

GO_REF:0000107

NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704

CARMIL2

capping protein regulator and myosin 1 linker 2

acts_upstream_of_or_within

(PMID:23793062)

PMID:23793062

NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152

DUSP10

dual specificity phosphatase 10

involved_in

GO_REF:0000107

NCBI chr38:16,196,354...16,233,640
Ensembl chr38:16,196,635...16,231,315

FOXO3

forkhead box O3

involved_in

GO_REF:0000107

NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198

forkhead box P3

acts_upstream_of_or_within
involved_in

GO_REF:0000107

NCBI chr X:42,331,229...42,362,841
Ensembl chr X:42,344,108...42,350,758

interleukin 2

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

IL4I1

interleukin 4 induced 1

involved_in

GO_REF:0000107

NCBI chr 1:106,636,282...106,673,438
Ensembl chr 1:106,657,477...106,673,422

KAT5

lysine acetyltransferase 5

involved_in

GO_REF:0000107

NCBI chr18:51,499,615...51,507,434
Ensembl chr18:51,499,938...51,576,699

galectin 9

involved_in

(PMID:25065622)

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

LOC100855640

butyrophilin subfamily 2 member A2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr35:24,251,221...24,265,040
Ensembl chr35:24,251,799...24,262,496

leukocyte immunoglobulin-like receptor subfamily B member 3

involved_in

(PMID:20935202), (PMID:22387553)

PMID:20935202 PMID:22387553

NCBI chr 1:102,779,562...102,786,924

LOC490269

complement receptor type 2

involved_in

(PMID:25742728)

PMID:25742728

NCBI chr 7:6,456,238...6,480,672

LOC609365

CD46 molecule, complement regulatory protein-like

involved_in

(PMID:12540904)

PMID:12540904

NCBI chr 7:6,602,762...6,646,561

microRNA mir-214

NCBI chr 7:26,818,559...26,818,668
Ensembl chr 7:26,818,559...26,818,670

RTP2

receptor transporter protein 2

involved_in

GO_REF:0000107

NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428

SOCS1

suppressor of cytokine signaling 1

involved_in

(PMID:22387553)

NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557

SOX12

SRY-box transcription factor 12

involved_in

GO_REF:0000107

NCBI chr24:20,509,931...20,515,013
Ensembl chr24:20,513,567...20,514,532

transforming growth factor beta 1

involved_in

GO_REF:0000107

NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885

V-set immunoregulatory receptor

involved_in

GO_REF:0000107

NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687

positive regulation of T cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

B2M

beta-2-microglobulin

involved_in

GO_REF:0000033

BCL10

BCL10 immune signaling adaptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368

CARD11

caspase recruitment domain family member 11

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094

CCDC88B

coiled-coil domain containing 88B

involved_in

GO_REF:0000107

NCBI chr18:52,722,197...52,737,023
Ensembl chr18:52,708,838...52,736,728

CCL2

C-C motif chemokine ligand 2

involved_in

(PMID:14662900)

PMID:14662900

NCBI chr 9:39,008,187...39,009,932

CCR2

C-C motif chemokine receptor 2

involved_in

GO_REF:0000107

NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698

CD3 epsilon subunit of T-cell receptor complex

acts_upstream_of_or_within

(PMID:12874832)

PMID:12874832

NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260

CD4

CD4 molecule

acts_upstream_of_or_within

(PMID:12421911)

PMID:12421911

NCBI chr27:38,204,003...38,250,771
Ensembl chr27:38,204,003...38,250,771

CD47

CD47 molecule

involved_in

GO_REF:0000107

NCBI chr33:13,315,984...13,362,971
Ensembl chr33:13,319,266...13,363,580

CORO1A

coronin 1A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:18,161,850...18,167,915
Ensembl chr 6:18,160,601...18,167,818

CYRIB

CYFIP related Rac1 interactor B

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr13:26,942,036...27,056,547
Ensembl chr13:26,942,229...27,003,644

DLA-DMA

major histocompatibility complex, class II, DM alpha

involved_in

GO_REF:0000033

NCBI chr12:2,516,974...2,534,085
Ensembl chr12:2,503,325...2,533,990

DLA-DMB

major histocompatibility complex, class II, DM beta

involved_in

GO_REF:0000033

NCBI chr12:2,503,325...2,508,380
Ensembl chr12:2,503,325...2,533,990

DLA-DOA

HLA class II histocompatibility antigen, DO alpha chain-like

involved_in

GO_REF:0000033

NCBI chr12:2,563,673...2,568,328
Ensembl chr12:2,563,673...2,568,328

DLA-DQA1

major histocompatibility complex, class II, DQ alpha 1

involved_in

GO_REF:0000033

NCBI chr12:2,221,181...2,227,600
Ensembl chr12:2,221,137...2,227,600

MHC class II DR alpha chain

involved_in

GO_REF:0000033

NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975

MHC class II DLA DRB1 beta chain

involved_in

GO_REF:0000033

NCBI chr12:2,151,409...2,164,564

FBXO38

F-box protein 38

involved_in

GO_REF:0000107

NCBI chr 4:60,360,543...60,416,727
Ensembl chr 4:60,320,648...60,417,205

FCHO1

FCH and mu domain containing endocytic adaptor 1

involved_in

GO_REF:0000107

NCBI chr20:45,106,982...45,131,173
Ensembl chr20:45,106,983...45,134,325

HSPD1

heat shock protein family D (Hsp60) member 1

involved_in

GO_REF:0000033

NCBI chr37:7,010,421...7,025,912

IGLL5

immunoglobulin lambda like polypeptide 5

involved_in

GO_REF:0000033

NCBI chr26:27,601,197...27,603,061

KLHL22

kelch like family member 22

involved_in

GO_REF:0000107

NCBI chr26:30,248,253...30,281,989
Ensembl chr26:30,248,240...30,281,843

LCK proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567

LOC100856137

HLA class II histocompatibility antigen, DQ beta 2 chain

involved_in

GO_REF:0000033

NCBI chr12:2,244,820...2,250,822
Ensembl chr12:2,244,820...2,251,662

LOC119868972

signal-regulatory protein beta-1-like

involved_in

GO_REF:0000033

LOC485809

signal-regulatory protein beta-1

involved_in

GO_REF:0000033

NCBI chr24:19,436,981...19,449,431

LOC609523

signal-regulatory protein beta-1

involved_in

GO_REF:0000033

NCBI chr24:19,524,314...19,555,872

MALT1

MALT1 paracaspase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927

NR5A2

nuclear receptor subfamily 5 group A member 2

involved_in

GO_REF:0000107

NCBI chr 7:2,925,915...3,062,118
Ensembl chr 7:2,927,326...3,062,348

PRKAA1

protein kinase AMP-activated catalytic subunit alpha 1

involved_in

GO_REF:0000107

NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841

protein kinase C theta

acts_upstream_of_or_within
involved_in

(PMID:12782715)

PMID:12782715

GO_REF:0000107

NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337

PYCARD

PYD and CARD domain containing

involved_in

GO_REF:0000107

NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240

RPS6KA4

ribosomal protein S6 kinase A4

involved_in

GO_REF:0000107

NCBI chr18:52,708,849...52,720,561
Ensembl chr18:52,708,838...52,736,728

SIRPA

signal regulatory protein alpha

involved_in

GO_REF:0000033

NCBI chr24:19,094,930...19,136,655

THY1

Thy-1 cell surface antigen

involved_in

PMID:7722293

NCBI chr 5:14,503,902...14,509,113
Ensembl chr 5:14,503,902...14,509,113

TNFSF11

TNF superfamily member 11

involved_in

GO_REF:0000107

NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645

YWHAG

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

involved_in

GO_REF:0000107

NCBI chr 6:7,504,834...7,548,097
Ensembl chr 6:7,507,608...7,532,409

positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD81

CD81 molecule

involved_in

(PMID:8766544)
(PMID:11046035)

PMID:8766544 PMID:11046035

NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868

DLA-DMB

major histocompatibility complex, class II, DM beta

involved_in

GO_REF:0000107

NCBI chr12:2,503,325...2,508,380
Ensembl chr12:2,503,325...2,533,990

galectin 9

involved_in

(PMID:16116184)

PMID:16116184

NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391

positive regulation of T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCR7

C-C motif chemokine receptor 7

involved_in

GO_REF:0000107

NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656

EPHB4

EPH receptor B4

acts_upstream_of_or_within

(PMID:15599401)

PMID:15599401

NCBI chr 6:8,925,303...8,943,284
Ensembl chr 6:8,924,686...8,942,324

EPHB6

EPH receptor B6

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr16:6,706,302...6,718,566
Ensembl chr16:6,706,313...6,718,566

TNF superfamily member 4

involved_in

(PMID:20639485)

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

positive regulation of T cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

BAD

BCL2 associated agonist of cell death

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405

CD27

CD27 molecule

involved_in

InterPro

GO_REF:0000002

NCBI chr27:38,534,704...38,537,806
Ensembl chr27:38,534,707...38,537,604

CD74

CD74 molecule

acts_upstream_of_or_within

(PMID:7679955), (PMID:8598040)
(PMID:9432982)

PMID:7679955 PMID:8598040 PMID:9432982

NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151

CYLD

CYLD lysine 63 deubiquitinase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175

DLA-DMA

major histocompatibility complex, class II, DM alpha

acts_upstream_of_or_within

(PMID:8598040)
(PMID:8638109)
(PMID:8598041), (PMID:9432982)

PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982

NCBI chr12:2,516,974...2,534,085
Ensembl chr12:2,503,325...2,533,990

DLA-DQA1

major histocompatibility complex, class II, DQ alpha 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:2,221,181...2,227,600
Ensembl chr12:2,221,137...2,227,600

GATA3

GATA binding protein 3

involved_in

GO_REF:0000107

NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760

IL12A

interleukin 12A

acts_upstream_of_or_within

(PMID:22968459)

PMID:22968459

NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550

IL1RL2

interleukin 1 receptor like 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:40,776,670...40,817,263
Ensembl chr10:40,778,590...40,816,044

interleukin 2

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

interleukin 2 receptor subunit alpha

NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643

IL36B

interleukin 36 beta

acts_upstream_of_or_within
involved_in

(PMID:22968459)

PMID:22968459

GO_REF:0000033

NCBI chr17:37,159,276...37,165,841
Ensembl chr17:37,159,434...37,165,423

interleukin 4

involved_in

(PMID:20554961)

PMID:20554961

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

IL7

interleukin 7

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737

LOC491316

midkine

involved_in

(PMID:28183532)

PMID:28183532

NCBI chr 9:55,100,491...55,101,081

PIK3R6

phosphoinositide-3-kinase regulatory subunit 6

involved_in

GO_REF:0000107

NCBI chr 5:33,472,240...33,528,369
Ensembl chr 5:33,472,771...33,528,400

protein tyrosine phosphatase receptor type C

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124

RAG1

recombination activating 1

involved_in

GO_REF:0000107

NCBI chr18:31,628,231...31,639,980
Ensembl chr18:31,630,737...31,641,660

RHOH

ras homolog family member H

involved_in

GO_REF:0000107

NCBI chr 3:72,272,446...72,277,015
Ensembl chr 3:72,276,418...72,276,993

WNT10B

Wnt family member 10B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr27:5,599,905...5,605,506
Ensembl chr27:5,601,089...5,605,501

XBP1

X-box binding protein 1

involved_in

GO_REF:0000107

NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105

ZAP70

zeta chain of T cell receptor associated protein kinase 70

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071

ZBTB1

zinc finger and BTB domain containing 1

involved_in

GO_REF:0000107

NCBI chr 8:38,933,721...38,959,306
Ensembl chr 8:38,933,805...38,959,306

ZMIZ1

zinc finger MIZ-type containing 1

involved_in

GO_REF:0000107

NCBI chr 4:28,807,368...29,035,946
Ensembl chr 4:28,854,908...29,045,986

positive regulation of T cell differentiation in thymus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

ADAM8

ADAM metallopeptidase domain 8

involved_in

GO_REF:0000107

NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747

EGR3

early growth response 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr25:34,591,691...34,597,144
Ensembl chr25:34,591,863...34,594,346

Indian hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr37:25,616,942...25,622,989

IL2RG

interleukin 2 receptor subunit gamma

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:55,480,846...55,488,485
Ensembl chr X:55,481,092...55,484,751

IL7R

interleukin 7 receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 4:72,633,528...72,668,242
Ensembl chr 4:72,636,325...72,668,300

RASGRP1

RAS guanyl releasing protein 1

involved_in

GO_REF:0000107

NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810

sonic hedgehog signaling molecule

involved_in

GO_REF:0000107

NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903

TESPA1

thymocyte expressed, positive selection associated 1

involved_in

(PMID:22561606)

PMID:22561606

NCBI chr27:424,836...460,114
Ensembl chr27:424,715...460,097

VNN1

vanin 1

involved_in

(PMID:8934567)

PMID:8934567

NCBI chr 1:25,678,039...25,704,579
Ensembl chr 1:25,678,042...25,696,807

positive regulation of T cell homeostatic proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD24 molecule

acts_upstream_of_or_within

(PMID:15477346)

PMID:15477346

NCBI chr12:64,239,957...64,245,114

positive regulation of T cell proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADK

adenosine kinase

decreased expression of mRNA under high glucose in the absence of insulin

RGD

PMID:16827901

RGD:2313341

NCBI chr 4:24,540,626...25,047,032
Ensembl chr 4:24,540,659...25,046,464

AIF1

allograft inflammatory factor 1

involved_in

GO_REF:0000107

NCBI chr12:1,104,350...1,106,179
Ensembl chr12:1,104,394...1,106,177

ANXA1

annexin A1

involved_in

GO_REF:0000107

NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011

BTNL2

butyrophilin like 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr12:2,085,589...2,106,787
Ensembl chr12:2,086,324...2,107,124

CARMIL2

capping protein regulator and myosin 1 linker 2

acts_upstream_of_or_within

(PMID:23793062)

PMID:23793062

NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152

CCDC88B

coiled-coil domain containing 88B

involved_in

GO_REF:0000107

NCBI chr18:52,722,197...52,737,023
Ensembl chr18:52,708,838...52,736,728

CCL19

C-C motif chemokine ligand 19

involved_in

(PMID:15845453)

NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365

CCL5

C-C motif chemokine ligand 5

involved_in

(PMID:18832695)

PMID:18832695

NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852

CD1D

CD1d molecule

involved_in

(PMID:19124746)

PMID:19124746

NCBI chr38:23,489,169...23,491,712

CD209

CD209 molecule

involved_in

(PMID:12421943)

PMID:12421943

NCBI chr20:52,517,759...52,542,085
Ensembl chr20:52,518,036...52,520,942

CD274 molecule

involved_in

RGD
GO_Central

PMID:21717117

GO_REF:0000033 RGD:9589064

NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522

CD276

CD276 molecule

involved_in
acts_upstream_of_or_within

PMID:11224528 PMID:16751379

(PMID:11224528)
(PMID:16751379)

HGNC-UCL
MGI

NCBI chr30:36,975,085...36,990,012
Ensembl chr30:36,975,085...36,988,924

CD28

CD28 molecule

involved_in
acts_upstream_of_or_within

ISS
IEA
IBA

UniProt
Ensembl
GO_Central

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107

NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854

CD3 epsilon subunit of T-cell receptor complex

acts_upstream_of_or_within
involved_in

(PMID:10072077), (PMID:10485657), (PMID:12874832), (PMID:15368291)
(PMID:12110186)

RGD
MGI
UniProt

PMID:10072077 PMID:10485657 PMID:10498748 PMID:12110186 PMID:12874832 More...

RGD:1600792

NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260

CD4 molecule

NCBI chr27:38,204,003...38,250,771
Ensembl chr27:38,204,003...38,250,771

CD40LG

CD40 ligand

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr X:107,001,421...107,023,007
Ensembl chr X:107,010,890...107,023,006

CD59 molecule

NCBI chr18:33,977,433...33,999,145
Ensembl chr18:33,977,480...33,998,329

CD6

CD6 molecule

involved_in

GO_REF:0000107

NCBI chr18:55,296,116...55,336,014
Ensembl chr18:55,296,986...55,335,880

CD80 molecule

acts_upstream_of_or_within
involved_in

PMID:9237108 PMID:23793062

(PMID:23793062)

RGD
MGI
GO_Central

GO_REF:0000033 RGD:632472

NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380

CD86

CD86 molecule

acts_upstream_of_or_within
involved_in

PMID:19107191 PMID:23793062

(PMID:23793062)

RGD
MGI
GO_Central

GO_REF:0000033 RGD:4892215

NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087

CORO1A

coronin 1A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:18,161,850...18,167,915
Ensembl chr 6:18,160,601...18,167,818

DHPS

deoxyhypusine synthase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:49,435,956...49,439,493
Ensembl chr20:49,435,844...49,439,479

DLA-DMB

major histocompatibility complex, class II, DM beta

involved_in

GO_REF:0000107

NCBI chr12:2,503,325...2,508,380
Ensembl chr12:2,503,325...2,533,990

DNAJA3

DnaJ heat shock protein family (Hsp40) member A3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:36,921,941...36,967,718
Ensembl chr 6:36,917,858...36,967,689

EFNB1

ephrin B1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:53,292,407...53,303,824
Ensembl chr X:53,292,565...53,304,600

HAVCR2

hepatitis A virus cellular receptor 2

involved_in

GO_REF:0000107

NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393

HES1

hes family bHLH transcription factor 1

acts_upstream_of_or_within

GO_REF:0000107

IFNG

interferon gamma

acts_upstream_of_or_within

(PMID:16280321)

PMID:16280321

NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698

IL12A

interleukin 12A

acts_upstream_of_or_within

(PMID:11057672)

PMID:11057672

NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550

interleukin 12B

acts_upstream_of_or_within
involved_in

GO_REF:0000107

NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228

IL15

interleukin 15

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr19:1,339,607...1,364,762
Ensembl chr19:1,339,967...1,364,762

IL1B

interleukin 1 beta

involved_in

GO_REF:0000107

NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458

IL2

interleukin 2

acts_upstream_of_or_within

PMID:6609839 PMID:6609879 PMID:6979751

RGD
Ensembl

GO_REF:0000107 RGD:1600093 RGD:2303493 RGD:2303494

NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394

IL21

interleukin 21

acts_upstream_of_or_within
involved_in

(PMID:17673207)

MGI
Ensembl

PMID:17673207

GO_REF:0000107

NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266

interleukin 23 subunit alpha

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

interleukin 2 receptor subunit alpha

NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643

IL3

interleukin 3

acts_upstream_of_or_within

(PMID:12714518), (PMID:15947484)

PMID:12714518 PMID:15947484

NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668

PMID:1588041 PMID:18997793

interleukin 4

involved_in
acts_upstream_of_or_within

ISS
ISO

(PMID:1588041), (PMID:18997793)

UniProt
MGI

GO_REF:0000024

NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534

interleukin 6

involved_in

GO_REF:0000107

NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519

IL6ST

interleukin 6 cytokine family signal transducer

involved_in

GO_REF:0000107

NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124

ITGAL

integrin subunit alpha L

acts_upstream_of_or_within

(PMID:1346270)

PMID:1346270

NCBI chr 6:17,605,611...17,645,134
Ensembl chr 6:17,605,760...17,644,986

Janus kinase 2

involved_in

GO_REF:0000107

NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997

Janus kinase 3

involved_in

PMID:9637481

NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805

KITLG

KIT ligand

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr15:29,591,068...29,671,985
Ensembl chr15:29,591,170...29,671,974

LEP

leptin

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395

LOC609365

CD46 molecule, complement regulatory protein-like

involved_in

(PMID:12540904)

PMID:12540904

NCBI chr 7:6,602,762...6,646,561

NCK1

NCK adaptor protein 1

involved_in

GO_REF:0000107

NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534

NCK2

NCK adaptor protein 2

involved_in

GO_REF:0000107

NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994

NCK associated protein 1 like

involved_in

GO_REF:0000107

NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439

NR5A2

nuclear receptor subfamily 5 group A member 2

involved_in

GO_REF:0000107

NCBI chr 7:2,925,915...3,062,118
Ensembl chr 7:2,927,326...3,062,348

programmed cell death 1 ligand 2

acts_upstream_of_or_within
involved_in

(PMID:11283156)

PMID:11283156

GO_REF:0000033

NCBI chr 1:93,631,676...93,698,560
Ensembl chr 1:93,631,979...93,689,266

PNP

purine nucleoside phosphorylase

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr15:17,808,454...17,815,987
Ensembl chr15:17,808,461...17,815,676

protein tyrosine phosphatase receptor type C

involved_in

GO_REF:0000107

NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124

RPS6KA4

ribosomal protein S6 kinase A4

involved_in

GO_REF:0000107

NCBI chr18:52,708,849...52,720,561
Ensembl chr18:52,708,838...52,736,728

SASH3

SAM and SH3 domain containing 3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:100,989,605...101,003,162
Ensembl chr X:100,989,685...101,001,885

SELENOK

selenoprotein K

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:36,109,095...36,115,792
Ensembl chr20:36,109,148...36,115,856

SLC4A1

solute carrier family 4 member 1

NCBI chr 9:19,142,884...19,159,449
Ensembl chr 9:19,146,480...19,157,915

SLC7A1

solute carrier family 7 member 1

acts_upstream_of

GO_REF:0000107

NCBI chr25:10,272,949...10,363,793
Ensembl chr25:10,292,926...10,359,383

sialophorin

acts_upstream_of_or_within

(PMID:11380685), (PMID:7790813)

PMID:7790813 PMID:11380685

NCBI chr 6:17,770,303...17,774,946

SPTA1

spectrin alpha, erythrocytic 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr38:23,052,046...23,118,933
Ensembl chr38:23,051,563...23,118,966

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103

TFRC

transferrin receptor

involved_in

IEA
ISS

GO_REF:0000024 GO_REF:0000107

NCBI chr33:29,206,024...29,237,221
Ensembl chr33:29,208,609...29,238,242

TNFRSF13C

TNF receptor superfamily member 13C

acts_upstream_of_or_within
involved_in

(PMID:15240667), (PMID:15368291)

GO_REF:0000033

NCBI chr10:23,430,960...23,434,972
Ensembl chr10:23,433,052...23,438,946

TNFSF13B

TNF superfamily member 13b

acts_upstream_of_or_within

(PMID:15240667), (PMID:15368291)

NCBI chr22:57,036,307...57,069,053
Ensembl chr22:57,036,292...57,068,320

TNF superfamily member 4

involved_in

GO_REF:0000033

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

TRAF6

TNF receptor associated factor 6

involved_in

GO_REF:0000107

NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641

TYK2

tyrosine kinase 2

involved_in

GO_REF:0000107

NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216

VCAM1

vascular cell adhesion molecule 1

involved_in

GO_REF:0000107

NCBI chr 6:49,341,669...49,359,841
Ensembl chr 6:49,342,151...49,359,933

VTCN1

V-set domain containing T cell activation inhibitor 1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr17:54,533,153...54,587,262
Ensembl chr17:54,536,026...54,587,110

ZP3

zona pellucida glycoprotein 3

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:7,586,212...7,594,610
Ensembl chr 6:7,585,970...7,594,610

ZP4

zona pellucida glycoprotein 4

involved_in

GO_REF:0000107

NCBI chr 4:2,324,657...2,332,357
Ensembl chr 4:2,324,226...2,331,470

positive regulation of T-helper 1 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA1

annexin A1

involved_in

GO_REF:0000107

NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011

CCL19

C-C motif chemokine ligand 19

involved_in

(PMID:15845453)

NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365

HLX

H2.0 like homeobox

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152

RIPK2

receptor interacting serine/threonine kinase 2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333

SOCS5

suppressor of cytokine signaling 5

involved_in

GO_REF:0000107

NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452

positive regulation of T-helper 17 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MALT1

MALT1 paracaspase

involved_in

GO_REF:0000107

NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927

MIR326

microRNA mir-326

acts_upstream_of_or_within

(PMID:19838199)

PMID:19838199

NCBI chr21:23,240,463...23,240,553
Ensembl chr21:23,240,463...23,240,553

NFKBID

NFKB inhibitor delta

involved_in

(PMID:25282160)

PMID:25282160

NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325

NFKBIZ

NFKB inhibitor zeta

involved_in

GO_REF:0000107

NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561

NLRP3

NLR family pyrin domain containing 3

involved_in

(PMID:26098997)

PMID:26098997

NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059

positive regulation of T-helper 17 cell lineage commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BRD2

bromodomain containing 2

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr12:2,534,034...2,546,029
Ensembl chr12:2,534,034...2,546,029

BRD4

bromodomain containing 4

involved_in

(PMID:28262505)

PMID:28262505

NCBI chr20:46,844,795...46,927,620
Ensembl chr20:46,891,514...46,927,608

EP300

E1A binding protein p300

involved_in

GO_REF:0000107

NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396

interleukin 23 subunit alpha

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359

OPA1

OPA1 mitochondrial dynamin like GTPase

involved_in

(PMID:36171294)

PMID:36171294

NCBI chr23:52,068,123...52,154,410
Ensembl chr23:52,068,118...52,151,593

positive regulation of T-helper 2 cell activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein kinase C theta

involved_in

GO_REF:0000107

NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337

TNF superfamily member 4

involved_in

(PMID:12496423)

PMID:12496423

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

positive regulation of T-helper 2 cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL18

interleukin 18

involved_in

GO_REF:0000107

NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348

IL4R

interleukin 4 receptor

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291

interleukin 6

acts_upstream_of_or_within

(PMID:12594267)

PMID:12594267

NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519

NLRP3

NLR family pyrin domain containing 3

involved_in

(PMID:26098997)

PMID:26098997

NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059

PRKCZ

protein kinase C zeta

involved_in

GO_REF:0000107

NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664

RARA

retinoic acid receptor alpha

involved_in

GO_REF:0000107

NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459

TNF superfamily member 4

involved_in

(PMID:18354165)

PMID:18354165

NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892

positive regulation of T-helper cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SHB

SH2 domain containing adaptor protein B

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325

regulation of cell-cell adhesion mediated by integrin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

involved_in

GO_REF:0000107

NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160

CD24 molecule

acts_upstream_of_or_within

(PMID:8145052)

PMID:8145052

NCBI chr12:64,239,957...64,245,114

DPP4

dipeptidyl peptidase 4

involved_in

GO_REF:0000107

NCBI chr36:7,398,713...7,472,554
Ensembl chr36:7,399,643...7,454,204

FERMT3

FERM domain containing kindlin 3

involved_in

GO_REF:0000033 GO_REF:0000107

NCBI chr18:52,833,954...52,851,775
Ensembl chr18:52,834,001...52,851,667

regulation of heterotypic cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FLOT2

flotillin 2

NOT|involved_in

(PMID:25204797)

PMID:25204797

NCBI chr 9:43,050,929...43,066,886
Ensembl chr 9:43,052,114...43,071,742

regulation of homophilic cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CEA cell adhesion molecule 1

involved_in

PMID:8576129

NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830

PTPRG

protein tyrosine phosphatase receptor type G

NOT|involved_in

(PMID:21724833)

PMID:21724833

NCBI chr20:28,777,306...29,481,097
Ensembl chr20:28,778,386...29,481,145

PTPRR

protein tyrosine phosphatase receptor type R

NOT|involved_in

(PMID:21724833)

PMID:21724833

NCBI chr10:12,385,121...12,618,438
Ensembl chr10:12,385,107...12,594,004

TENM3

teneurin transmembrane protein 3

involved_in
NOT|involved_in

(PMID:29414938)

PMID:29414938

NCBI chr16:47,440,673...47,883,311
Ensembl chr16:47,441,348...48,044,322
Ensembl chr16:47,441,348...48,044,322

regulation of leukocyte adhesion to arterial endothelial cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ZDHHC21

zinc finger DHHC-type palmitoyltransferase 21

involved_in

GO_REF:0000107

NCBI chr11:35,073,639...35,139,854
Ensembl chr11:35,079,886...35,131,372

regulation of leukocyte adhesion to vascular endothelial cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

fucosyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303

regulation of leukocyte cell-cell adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

fucosyltransferase 4

involved_in

(PMID:23192350)

PMID:23192350

NCBI chr21:6,386,665...6,390,109
Ensembl chr21:6,389,021...6,390,793

fucosyltransferase 4

involved_in

GO_REF:0000107

fucosyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303

FUT9

fucosyltransferase 9

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr12:54,581,280...54,784,072
Ensembl chr12:54,771,426...54,772,505

regulation of leukocyte tethering or rolling

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

fucosyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303

FUT9

fucosyltransferase 9

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr12:54,581,280...54,784,072
Ensembl chr12:54,771,426...54,772,505

regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADGRG1

adhesion G protein-coupled receptor G1

involved_in

(PMID:33097663)

PMID:33097663

NCBI chr 2:58,805,737...58,842,618
Ensembl chr 2:58,805,834...58,852,684

LYN

LYN proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507

PRKCA

protein kinase C alpha

involved_in

GO_REF:0000107

NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630

protein kinase C theta

involved_in

GO_REF:0000107

NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337

spleen associated tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583

VPS33B

VPS33B late endosome and lysosome associated

involved_in

GO_REF:0000107

NCBI chr 3:53,220,199...53,239,738
Ensembl chr 3:53,220,194...53,239,732

regulation of synaptic membrane adhesion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LRFN3

leucine rich repeat and fibronectin type III domain containing 3

involved_in

PMID:27480238

NCBI chr 1:116,727,092...116,734,844

MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2

involved_in

PMID:23751499

NCBI chr18:17,973,058...19,098,785
Ensembl chr18:17,918,928...18,930,059

MAPK14

mitogen-activated protein kinase 14

involved_in

GO_REF:0000107

NCBI chr12:5,145,647...5,221,558
Ensembl chr12:5,146,037...5,220,603

MDGA1

MAM domain containing glycosylphosphatidylinositol anchor 1

involved_in

GO_REF:0000107

NCBI chr12:6,655,586...6,716,619
Ensembl chr12:6,659,910...6,686,760

MDGA2

MAM domain containing glycosylphosphatidylinositol anchor 2

involved_in

(PMID:27608760)

SynGO

PMID:27608760

NCBI chr 8:23,827,284...24,608,003
Ensembl chr 8:23,832,475...24,607,866

PCDH8

protocadherin 8

involved_in

PMID:17988630

NCBI chr22:9,860,590...9,865,298
Ensembl chr22:9,860,827...9,865,412

TAOK2

TAO kinase 2

involved_in

PMID:17988630

NCBI chr 6:18,014,685...18,029,188
Ensembl chr 6:18,000,138...18,029,185

T cell costimulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CARD11

caspase recruitment domain family member 11

involved_in

GO_REF:0000107

NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094

CAV1

caveolin 1

involved_in

GO_REF:0000024 GO_REF:0000107

NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935

CCL19

C-C motif chemokine ligand 19

involved_in

(PMID:15845453)

NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365

CCL21

C-C motif chemokine ligand 21

involved_in

(PMID:15845453)

NCBI chr11:51,375,107...51,375,790

CD160

CD160 molecule

involved_in

(PMID:11978774), (PMID:9973372)

PMID:9973372 PMID:11978774

NCBI chr17:58,548,137...58,564,077
Ensembl chr17:58,555,851...58,563,341

CD24 molecule

involved_in

(PMID:11272271)

PMID:11272271

NCBI chr12:64,239,957...64,245,114

CD274 molecule

involved_in

GO_REF:0000033

NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522

CD28

CD28 molecule

acts_upstream_of_or_within
involved_in

ISO
IEA
IBA

RGD
Ensembl
GO_Central

PMID:7730618

GO_REF:0000033 GO_REF:0000107 RGD:2303155

NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854

CD3 epsilon subunit of T-cell receptor complex

acts_upstream_of_or_within

(PMID:23793062)

PMID:23793062

NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260

CD5

CD5 molecule

involved_in
acts_upstream_of_or_within

GO_REF:0000033 GO_REF:0000107

NCBI chr18:55,216,415...55,235,567
Ensembl chr18:55,217,276...55,235,405

PMID:1385153 PMID:15568026

CD80 molecule

involved_in
acts_upstream_of_or_within

IEA
ISO
IBA

(PMID:1385153), (PMID:15568026)

InterPro
MGI
GO_Central

GO_REF:0000002 GO_REF:0000033

NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380

CD86

CD86 molecule

involved_in

GO_REF:0000033

NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087

DPP4

dipeptidyl peptidase 4

involved_in

GO_REF:0000107

NCBI chr36:7,398,713...7,472,554
Ensembl chr36:7,399,643...7,454,204

EFNB1

ephrin B1

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr X:53,292,407...53,303,824
Ensembl chr X:53,292,565...53,304,600

EFNB2

ephrin B2

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr22:55,567,992...55,609,210
Ensembl chr22:55,566,039...55,609,443

EFNB3

ephrin B3

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 5:32,588,062...32,592,390
Ensembl chr 5:32,574,134...32,594,333

HHLA2

HHLA2 member of B7 family

involved_in

(PMID:23784006)

NCBI chr33:13,606,724...13,622,678

ICOS

inducible T cell costimulator

involved_in

ISO
IBA
IEA

RGD
GO_Central
InterPro

PMID:11006126

GO_REF:0000002 GO_REF:0000033 RGD:631942

NCBI chr37:12,663,839...12,735,266
Ensembl chr37:12,670,999...12,733,458

LGALS1

galectin 1

acts_upstream_of_or_within

(PMID:22357632)

PMID:22357632

NCBI chr10:26,932,351...26,935,580
Ensembl chr10:26,932,301...26,935,646

LGALS8

galectin 8

acts_upstream_of_or_within

GO_REF:0000107

NCBI chr 4:3,548,066...3,581,382
Ensembl chr 4:3,533,200...3,567,311

LOC100684393

small nuclear ribonucleoprotein-associated proteins B and B'

involved_in

(PMID:23784006)

NCBI chr20:55,349,126...55,350,721

programmed cell death 1 ligand 2

involved_in

GO_REF:0000033

NCBI chr 1:93,631,676...93,698,560
Ensembl chr 1:93,631,979...93,689,266

sialophorin

acts_upstream_of_or_within

(PMID:10429671), (PMID:11380685), (PMID:7790813)

PMID:7790813 PMID:10429671 PMID:11380685

NCBI chr 6:17,770,303...17,774,946

TNFRSF13C

TNF receptor superfamily member 13C

acts_upstream_of_or_within
involved_in

(PMID:15240667), (PMID:15368291)

GO_REF:0000033

NCBI chr10:23,430,960...23,434,972
Ensembl chr10:23,433,052...23,438,946

TNF receptor superfamily member 14

involved_in

(PMID:10754304)

PMID:10754304

NCBI chr 5:57,386,190...57,416,864
Ensembl chr 5:57,411,529...57,416,512

TNFSF13B

TNF superfamily member 13b

acts_upstream_of_or_within

(PMID:15240667), (PMID:15368291)

NCBI chr22:57,036,307...57,069,053
Ensembl chr22:57,036,292...57,068,320

TNFSF14

TNF superfamily member 14

involved_in
acts_upstream_of_or_within

GO_REF:0000107

NCBI chr20:53,604,101...53,607,522
Ensembl chr20:53,603,709...53,607,522

VAV1

vav guanine nucleotide exchange factor 1

involved_in