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ONTOLOGY REPORT - ANNOTATIONS

Term:pituitary gland development
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Accession:GO:0021983 term browser browse the term
Definition:The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
Synonyms:related_synonym: hypophysis development


show annotations for term's descendants           Sort by:
pituitary gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IEP RGD PMID:18160680 RGD:2325274 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 IEP RGD PMID:17180597 RGD:2306413 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 IEP RGD PMID:17180597 RGD:2306413 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO
IEA		 MGI:1857137 (PMID:9806931)
GO_REF:0000107		 RGD
Ensembl		 PMID:9806931 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO
IEA		 MGI:2158342|MGI:2158390 (PMID:17359964)
GO_REF:0000107		 RGD
Ensembl		 PMID:17359964 GO_REF:0000107 NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Cdh1 cadherin 1 IEP RGD PMID:17373711 RGD:2289637 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:2176173|MGI:2181395 (PMID:16141355)
GO_REF:0000107		 RGD
Ensembl		 PMID:16141355 GO_REF:0000107 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IEP RGD PMID:8946059 RGD:2313681 NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO
IEA		 MGI:1859647 (PMID:11062007)
GO_REF:0000107		 RGD
Ensembl		 PMID:11062007 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO
IEA		 MGI:2179995|MGI:3628639 (PMID:16543408)
GO_REF:0000107		 RGD
Ensembl		 PMID:16543408 GO_REF:0000107 NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gli1 GLI family zinc finger 1 acts_upstream_of_or_within ISO
IEA		 MGI:95728 (PMID:10725236)
GO_REF:0000107		 RGD
Ensembl		 PMID:10725236 GO_REF:0000107 NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95727 (PMID:10725236) RGD PMID:10725236 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO
IEA		 MGI:104876|MGI:2149672 (PMID:17015435), (PMID:17426285)
GO_REF:0000107		 RGD
Ensembl		 PMID:17015435 PMID:17426285 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hesx1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:26781211)
GO_REF:0000107
MGI:102764|MGI:1931124|MGI:3822474|MGI:3822475 (PMID:11731482), (PMID:18775421), (PMID:19093031), (PMID:20181723), (PMID:9620767)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9620767 PMID:11731482 PMID:18775421 PMID:19093031 PMID:20181723 More... GO_REF:0000033 GO_REF:0000107 NCBI chr16:2,198,589...2,200,694
Ensembl chr16:2,191,852...2,193,957 		JBrowse link
G Hmga2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO
IEA		 MGI:1856426 (PMID:504232)
GO_REF:0000107		 RGD
Ensembl		 PMID:504232 GO_REF:0000107 NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Inhbb inhibin subunit beta B IEP RGD PMID:18160680 RGD:2325274 NCBI chr13:33,083,671...33,089,373
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:2182246 (PMID:9806931)
GO_REF:0000107		 RGD
Ensembl		 PMID:9806931 GO_REF:0000107 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Kdm1a lysine demethylase 1A acts_upstream_of_or_within ISO MGI:3711561 (PMID:17392792) RGD PMID:17392792 NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO
IEA		 MGI:2385819 (PMID:18037398)
GO_REF:0000107		 RGD
Ensembl		 PMID:18037398 GO_REF:0000107 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Msx1 msh homeobox 1 IEP RGD PMID:16451220 RGD:5132608 NCBI chr14:77,185,802...77,189,735
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Nkx2-1 NK2 homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857494 (PMID:9806931)
GO_REF:0000107		 RGD
Ensembl		 PMID:9806931 GO_REF:0000107 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nog noggin acts_upstream_of_or_within ISO
IEA		 MGI:1862000 (PMID:17359964)
GO_REF:0000107		 RGD
Ensembl		 PMID:17359964 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Pax6 paired box 6 acts_upstream_of_or_within ISO
IEA		 MGI:1856155|MGI:1934347 (PMID:10588713)
GO_REF:0000107		 RGD
Ensembl		 PMID:10588713 GO_REF:0000107 NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP RGD PMID:15208361 RGD:2308902 NCBI chr 2:6,130,045...6,176,974
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pitx1 paired-like homeodomain 1 acts_upstream_of_or_within ISO
IEA		 MGI:1934200 (PMID:10049363)
GO_REF:0000107		 RGD
Ensembl		 PMID:10049363 GO_REF:0000107 NCBI chr17:8,794,051...8,805,477
Ensembl chr17:8,794,134...8,800,291 		JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857844|MGI:1857846|MGI:2384494 (PMID:10498698), (PMID:10499586) RGD PMID:10498698 PMID:10499586 NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024 (PMID:16556738) RGD PMID:16556738 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1856842 (PMID:11731482)
GO_REF:0000002
GO_REF:0000107		 RGD
InterPro
Ensembl		 PMID:11731482 GO_REF:0000002 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3583755 (PMID:17015435) RGD PMID:17015435 NCBI chr14:61,551,366...61,736,220
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Sall1 spalt-like transcription factor 1 involved_in ISO
IEA		 (PMID:12065233)
GO_REF:0000107		 RGD
Ensembl		 PMID:12065233 GO_REF:0000107 NCBI chr19:34,179,316...34,196,278
Ensembl chr19:18,007,503...18,022,705 		JBrowse link
G Six3 SIX homeobox 3 acts_upstream_of_or_within
involved_in		 ISO MGI:96071 (PMID:18775421) RGD PMID:18775421 NCBI chr 6:14,791,937...14,796,365
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Sox2 SRY-box transcription factor 2 involved_in ISO
IEA		 (PMID:18285410)
GO_REF:0000107		 RGD
Ensembl		 PMID:18285410 GO_REF:0000107 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox3 SRY-box transcription factor 3 involved_in ISO (PMID:14981518) RGD PMID:14981518 NCBI chr  X:144,344,892...144,346,971
Ensembl chr  X:139,309,329...139,310,678 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:8770891 RGD:4892048 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Tbx19 T-box transcription factor 19 acts_upstream_of_or_within ISO
IEA		 (PMID:11447259)
GO_REF:0000107		 RGD
Ensembl		 PMID:11447259 GO_REF:0000107 NCBI chr13:79,983,935...80,016,219
Ensembl chr13:77,450,849...77,504,163 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (PMID:17919533) RGD PMID:17919533 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
adenohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO
IEA		 MGI:3576789 (PMID:9140068)
GO_REF:0000107		 RGD
Ensembl		 PMID:9140068 GO_REF:0000107 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ghrh growth hormone releasing hormone acts_upstream_of_or_within TAS
ISO		 MGI:3051561 (PMID:15985453) RGD PMID:15985453 PMID:12511850 RGD:1601329 NCBI chr 3:166,412,763...166,432,519
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor acts_upstream_of_or_within ISO
IEA		 MGI:1856425 (PMID:1270792), (PMID:1329576), (PMID:1504465)
GO_REF:0000107		 RGD
Ensembl		 PMID:1270792 PMID:1329576 PMID:1504465 GO_REF:0000107 NCBI chr 4:85,830,345...85,863,127
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Gsx1 GS homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:2154448 (PMID:8631293)
GO_REF:0000107		 RGD
Ensembl		 PMID:8631293 GO_REF:0000107 NCBI chr12:12,994,588...12,996,874
Ensembl chr12:7,881,460...7,882,753 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO
IEA		 MGI:3808031 (PMID:18996108)
GO_REF:0000107		 RGD
Ensembl		 PMID:18996108 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 IMP RGD PMID:16216912 RGD:1601440 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO
IEA		 (PMID:18996108)
GO_REF:0000107		 RGD
Ensembl		 PMID:18996108 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO
IEA		 MGI:2386303 (PMID:9247269)
GO_REF:0000107		 RGD
Ensembl		 PMID:9247269 GO_REF:0000107 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within IEP
ISO		 MGI:2449045 (PMID:16932809) RGD PMID:16932809 PMID:21815952 RGD:8661681 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
adenohypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duox2 dual oxidase 2 acts_upstream_of_or_within ISO
IEA		 MGI:3712359 (PMID:17440044)
GO_REF:0000107		 RGD
Ensembl		 PMID:17440044 GO_REF:0000107 NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
corticotropin hormone secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
hypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:3690463 (PMID:16678101)
GO_REF:0000107		 RGD
Ensembl		 PMID:16678101 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO
IEA		 MGI:1857617 (PMID:15037319)
GO_REF:0000107		 RGD
Ensembl		 PMID:15037319 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
neurohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otp orthopedia homeobox acts_upstream_of_or_within ISO
IEA		 MGI:2180541 (PMID:10557207)
GO_REF:0000107		 RGD
Ensembl		 PMID:10557207 GO_REF:0000107 NCBI chr 2:27,842,892...27,851,093
Ensembl chr 2:26,108,163...26,116,359 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857996 (PMID:8543156)
GO_REF:0000107		 RGD
Ensembl		 PMID:8543156 GO_REF:0000107 NCBI chr 5:40,874,631...40,880,539
Ensembl chr 5:36,077,930...36,083,838 		JBrowse link
prolactin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO
IEA		 MGI:2385819 (PMID:8638120)
GO_REF:0000107		 RGD
Ensembl		 PMID:8638120 GO_REF:0000107 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
somatotropin secreting cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrhr growth hormone releasing hormone receptor acts_upstream_of_or_within ISO
IEA		 MGI:1856425 (PMID:6116352), (PMID:6194978)
GO_REF:0000107		 RGD
Ensembl		 PMID:6116352 PMID:6194978 GO_REF:0000107 NCBI chr 4:85,830,345...85,863,127
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:2158737 (PMID:17015435) RGD PMID:17015435 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
somatotropin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO
IEA		 MGI:2385819 (PMID:8638120)
GO_REF:0000107		 RGD
Ensembl		 PMID:8638120 GO_REF:0000107 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024 (PMID:1334535), (PMID:6194978) RGD PMID:1334535 PMID:6194978 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:1856842 (PMID:6194978)
GO_REF:0000107		 RGD
Ensembl		 PMID:6194978 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO
IEA		 MGI:1857453 (PMID:18351662)
GO_REF:0000107		 RGD
Ensembl		 PMID:18351662 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO
IEA		 MGI:2179995|MGI:3628639 (PMID:16543408)
GO_REF:0000107		 RGD
Ensembl		 PMID:16543408 GO_REF:0000107 NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO
IEA		 MGI:2385819 (PMID:8638120)
GO_REF:0000107		 RGD
Ensembl		 PMID:8638120 GO_REF:0000107 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO
IEA		 MGI:1857453 (PMID:18351662)
GO_REF:0000107		 RGD
Ensembl		 PMID:18351662 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    developmental process 7160
      anatomical structure development 6656
        diencephalon development 104
          pituitary gland development 49
            adenohypophysis development + 16
            hypophysis morphogenesis + 3
            neurohypophysis development + 2
Path 2
Term Annotations click to browse term
  biological_process 20567
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            nervous system development 2881
              central nervous system development 1238
                brain development 912
                  forebrain development 564
                    diencephalon development 104
                      pituitary gland development 49
                        adenohypophysis development + 16
                        hypophysis morphogenesis + 3
                        neurohypophysis development + 2
paths to the root