Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:optic nerve development
go back to main search page
Accession:GO:0021554 term browser browse the term
Definition:The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
Synonyms:exact_synonym: cranial nerve 2 development;   cranial nerve II development
 related_synonym: CN II development


show annotations for term's descendants           Sort by:
optic nerve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh7 atonal bHLH transcription factor 7 acts_upstream_of_or_within ISO
IEA 		(PMID:21441919)
GO_REF:0000107 		RGD
Ensembl		 PMID:21441919 GO_REF:0000107 NCBI chr20:25,530,826...25,531,275
Ensembl chr20:25,530,826...25,531,275 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B IEP RGD PMID:22473424 RGD:10411906 NCBI chr 3:27,779,133...27,944,292
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C IEP RGD PMID:22473424 RGD:10411906 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IEP RGD PMID:22473424 RGD:10411906 NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Dcc DCC netrin 1 receptor IEP RGD PMID:22473424 RGD:10411906 NCBI chr18:67,144,272...68,248,159
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO
IEA 		(PMID:21743013)
GO_REF:0000107 		RGD
Ensembl		 PMID:21743013 GO_REF:0000107 NCBI chr 7:86,265,651...86,544,488
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400 		JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138 		JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744 		JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968 		JBrowse link
G Kcnc3 potassium voltage-gated channel subfamily C member 3 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 1:95,080,960...95,095,165
Ensembl chr 1:95,080,960...95,095,160 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 2:195,063,967...195,100,244
Ensembl chr 2:195,071,769...195,099,233 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP RGD PMID:15198689 RGD:2326047 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 IEP RGD PMID:12139919 RGD:727395 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Nav2 neuron navigator 2 acts_upstream_of_or_within ISO MGI:3054375 (PMID:15158073) RGD PMID:15158073 NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO
IEA 		(PMID:29079753)
GO_REF:0000107 		RGD
Ensembl		 PMID:29079753 GO_REF:0000107 NCBI chr  X:8,379,569...8,404,019
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nkx2-2 NK2 homeobox 2 IEP RGD PMID:15048854 RGD:2306244 NCBI chr 3:155,072,621...155,083,699
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:8951055) 		UniProt
RGD		 PMID:8951055 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Rpl24 ribosomal protein L24 acts_upstream_of_or_within ISO MGI:1856685 (PMID:9331275) RGD PMID:9331275 NCBI chr11:44,653,937...44,659,346
Ensembl chr11:44,653,937...44,659,370 		JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 8:128,374,441...128,444,718
Ensembl chr 8:119,496,769...119,567,044 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 3:70,710,862...70,845,569
Ensembl chr 3:50,302,877...50,437,214 		JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 IEP RGD PMID:22473424 RGD:10411906 NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292 		JBrowse link
G Slc25a46 solute carrier family 25, member 46 acts_upstream_of_or_within ISO
IEA 		MGI:6358090 (PMID:28934388)
GO_REF:0000107 		RGD
Ensembl		 PMID:28934388 GO_REF:0000107 NCBI chr18:23,215,954...23,244,917
Ensembl chr18:23,215,962...23,244,314 		JBrowse link
G Slc38a8 solute carrier family 38, member 8 acts_upstream_of_or_within ISO
IEA 		(PMID:37862028)
GO_REF:0000107 		RGD
Ensembl		 PMID:37862028 GO_REF:0000107 NCBI chr19:64,432,524...64,468,852
Ensembl chr19:47,525,301...47,554,726 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 acts_upstream_of_or_within ISO
IEA 		MGI:3852642 (PMID:20711468)
GO_REF:0000107 		RGD
Ensembl		 PMID:20711468 GO_REF:0000107 NCBI chr 1:210,556,270...210,568,021
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
G Tmem126a transmembrane protein 126A involved_in ISO
IEA 		(PMID:19327736)
GO_REF:0000107 		RGD
Ensembl		 PMID:19327736 GO_REF:0000107 NCBI chr 1:144,424,481...144,430,730
Ensembl chr 1:144,422,703...144,430,628 		JBrowse link
optic chiasma development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:8951055) 		UniProt
RGD		 PMID:8951055 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
optic nerve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253|MGI:2158714 (PMID:11344259), (PMID:12097474) RGD PMID:11344259 PMID:12097474 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Ephb1 Eph receptor B1 acts_upstream_of_or_within ISO
IEA 		MGI:2677305 (PMID:12971893)
GO_REF:0000107 		RGD
Ensembl		 PMID:12971893 GO_REF:0000107 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G Ephb2 Eph receptor B2 acts_upstream_of_or_within ISO
IEA 		MGI:2149765 (PMID:12971893)
GO_REF:0000107 		RGD
Ensembl		 PMID:12971893 GO_REF:0000107 NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO
IEA 		MGI:1856276 (PMID:16342201)
GO_REF:0000107 		RGD
Ensembl		 PMID:16342201 GO_REF:0000107 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:8951055) 		UniProt
RGD		 PMID:8951055 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
optic nerve structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna2 potassium voltage-gated channel subfamily A member 2 acts_upstream_of_or_within ISO
IEA 		MGI:3043422 (PMID:15102918)
GO_REF:0000107 		RGD
Ensembl		 PMID:15102918 GO_REF:0000107 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:8951055) 		UniProt
RGD		 PMID:8951055 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
positive regulation of optic nerve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:18083586) 		UniProt
RGD		 PMID:18083586 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        nerve development 125
          cranial nerve development 79
            optic nerve development 31
              optic chiasma development 1
              optic nerve maturation 0
              optic nerve morphogenesis + 6
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            nervous system development 2881
              nerve development 125
                cranial nerve development 79
                  optic nerve development 31
                    optic chiasma development 1
                    optic nerve maturation 0
                    optic nerve morphogenesis + 6
paths to the root