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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear cyclin-dependent protein kinase holoenzyme complex
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Accession:GO:0019908 term browser browse the term
Definition:Cyclin-dependent protein kinase (CDK) complex found in the nucleus.
Synonyms:broad_synonym: CDK holoenzyme


show annotations for term's descendants           Sort by:
nuclear cyclin-dependent protein kinase holoenzyme complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bccip BRCA2 and CDKN1A interacting protein part_of ISO
IEA 		(PMID:10878006)
GO_REF:0000107 		RGD
Ensembl		 PMID:10878006 GO_REF:0000107 NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:197,942,190...197,956,378 		JBrowse link
G Cdk12 cyclin-dependent kinase 12 part_of IDA PMID:16537916 UniProt PMID:16537916 RGD:8553775 NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,767,206...83,777,183
Ensembl chr10:83,767,206...83,777,183 		JBrowse link
G Cdk13 cyclin-dependent kinase 13 part_of ISO
IEA 		(PMID:17261272)
GO_REF:0000107 		RGD
Ensembl		 PMID:17261272 GO_REF:0000107 NCBI chr17:51,945,975...52,040,218
Ensembl chr17:51,946,701...52,037,257 		JBrowse link
CKM complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnc cyclin C part_of IEA
ISO 		GO_REF:0000107
GO_REF:0000117
(PMID:19047373) 		Ensembl
UniProt
RGD		 PMID:19047373 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:40,063,589...40,081,731
Ensembl chr 5:40,063,623...40,093,370 		JBrowse link
G Cdk8 cyclin-dependent kinase 8 part_of ISO (PMID:19047373) RGD PMID:19047373 NCBI chr12:13,851,024...13,919,017
Ensembl chr12:13,851,024...13,917,992 		JBrowse link
G Med12 mediator complex subunit 12 part_of ISO
IEA 		(PMID:19047373)
GO_REF:0000107 		RGD
Ensembl		 PMID:19047373 GO_REF:0000107 NCBI chr  X:70,444,615...70,467,780
Ensembl chr  X:70,444,705...70,467,708 		JBrowse link
G Med13 mediator complex subunit 13 part_of ISO
IEA 		(PMID:19047373)
GO_REF:0000107 		RGD
Ensembl		 PMID:19047373 GO_REF:0000107 NCBI chr10:71,584,354...71,674,614
Ensembl chr10:71,584,354...71,673,901 		JBrowse link
core TFIIH complex portion of holo TFIIH complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2h2 general transcription factor IIH subunit 2 part_of ISS
ISO 		GO_REF:0000024
(PMID:27193682) 		UniProt
RGD		 PMID:27193682 GO_REF:0000024 NCBI chr 2:33,358,863...33,386,726
Ensembl chr 2:33,358,869...33,386,688 		JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 part_of ISO
IEA
ISS 		(PMID:27193682)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:27193682 GO_REF:0000024 GO_REF:0000107 NCBI chr12:37,669,995...37,687,505
Ensembl chr12:37,669,997...37,686,466 		JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 part_of ISO (PMID:27193682) RGD PMID:27193682 NCBI chr20:3,076,110...3,081,805
Ensembl chr20:3,076,088...3,081,760 		JBrowse link
cyclin/CDK positive transcription elongation factor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 part_of ISO (PMID:23752591) RGD PMID:23752591 NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923 		JBrowse link
G Ccnk cyclin K part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:132,854,428...132,877,604
Ensembl chr 6:132,854,700...132,877,602 		JBrowse link
G Ccnt1 cyclin T1 part_of IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:15905409), (PMID:18566585), (PMID:9499409) 		GO_Central
Ensembl
RGD		 PMID:9499409 PMID:15905409 PMID:18566585 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:131,566,176...131,596,988
Ensembl chr 7:131,566,176...131,596,938 		JBrowse link
G Ccnt2 cyclin T2 part_of IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:9499409) 		GO_Central
Ensembl
RGD		 PMID:9499409 GO_REF:0000033 GO_REF:0000107 NCBI chr13:41,804,007...41,845,641
Ensembl chr13:41,804,046...41,844,488 		JBrowse link
G Cdk12 cyclin-dependent kinase 12 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,767,206...83,777,183
Ensembl chr10:83,767,206...83,777,183 		JBrowse link
G Cdk13 cyclin-dependent kinase 13 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:51,945,975...52,040,218
Ensembl chr17:51,946,701...52,037,257 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 part_of ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15905409), (PMID:18566585), (PMID:9499409)
(PMID:23752591) 		UniProt
Ensembl
RGD		 PMID:9499409 PMID:15905409 PMID:18566585 PMID:23752591 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:36,394,168...36,399,016
Ensembl chr 3:36,394,169...36,399,528 		JBrowse link
G Rb1 RB transcriptional corepressor 1 located_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:12037672) 		UniProt
Ensembl
RGD		 PMID:12037672 GO_REF:0000024 GO_REF:0000107 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Snw1 SNW domain containing 1 located_in ISO (PMID:15905409) RGD PMID:15905409 NCBI chr 6:112,826,374...112,850,459
Ensembl chr 6:112,826,381...112,858,180 		JBrowse link
P-TEFb complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnt1 cyclin T1 part_of ISO
IEA 		(PMID:18483487), (PMID:28431135), (PMID:29849146), (PMID:30134174)
GO_REF:0000107 		RGD
Ensembl		 PMID:18483487 PMID:28431135 PMID:29849146 PMID:30134174 GO_REF:0000107 NCBI chr 7:131,566,176...131,596,988
Ensembl chr 7:131,566,176...131,596,938 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 part_of ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:18483487), (PMID:30134174) 		UniProt
Ensembl
RGD		 PMID:18483487 PMID:30134174 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:36,394,168...36,399,016
Ensembl chr 3:36,394,169...36,399,528 		JBrowse link
transcription factor TFIIH holo complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnh cyclin H part_of ISS
ISO 		GO_REF:0000024
(PMID:9852112) 		UniProt
RGD		 PMID:9852112 GO_REF:0000024 NCBI chr 2:17,570,449...17,591,078
Ensembl chr 2:17,570,263...17,614,860 		JBrowse link
G Cdk7 cyclin-dependent kinase 7 part_of IDA
IEA
ISO
ISS 		GO_REF:0000107
GO_REF:0000002
(PMID:9852112)
GO_REF:0000024 		Ensembl
InterPro
RGD
UniProt		 PMID:9852112 PMID:7553866 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107, RGD:9590319 NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit part_of ISO
IEA 		(PMID:9852112)
GO_REF:0000107 		RGD
Ensembl		 PMID:9852112 GO_REF:0000107 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102 		JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit part_of ISS
IBA
ISO 		GO_REF:0000024
GO_REF:0000033
(PMID:9852112) 		UniProt
GO_Central
RGD		 PMID:9852112 GO_REF:0000024 GO_REF:0000033 NCBI chr18:24,157,831...24,188,543
Ensembl chr18:24,148,084...24,190,898 		JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 IDA RGD PMID:7553866 RGD:9590319 NCBI chr15:57,615,361...57,736,477
Ensembl chr15:57,614,841...57,736,516 		JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 part_of IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:9852112) 		Ensembl
GO_Central
RGD		 PMID:9852112 PMID:7553866 GO_REF:0000033 GO_REF:0000107, RGD:9590319 NCBI chr 1:106,457,692...106,485,729
Ensembl chr 1:106,457,394...106,485,727 		JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 part_of ISS
IBA
ISO
IEA 		GO_REF:0000024
GO_REF:0000033
(PMID:9852112)
GO_REF:0000104 		UniProt
GO_Central
RGD		 PMID:9852112 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:33,358,863...33,386,726
Ensembl chr 2:33,358,869...33,386,688 		JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 part_of ISO
IEA
IBA
ISS 		(PMID:9852112)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000104
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:9852112 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr12:37,669,995...37,687,505
Ensembl chr12:37,669,997...37,686,466 		JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 part_of ISO (PMID:9852112) RGD PMID:9852112 NCBI chr20:3,076,110...3,081,805
Ensembl chr20:3,076,088...3,081,760 		JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:49,061,904...49,068,612
Ensembl chr 1:49,061,959...49,070,039 		JBrowse link
G LOC120103497 general transcription factor IIH subunit 5-like part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:32,828,646...32,833,974
Ensembl chr 6:32,830,827...32,831,042 		JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase part_of ISO
IEA
IBA 		(PMID:9852112)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
GO_REF:0000033 		RGD
Ensembl
InterPro
UniProt
GO_Central		 PMID:9852112 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:97,550,566...97,706,598
Ensembl chr 6:97,550,543...97,706,595 		JBrowse link
transcription factor TFIIK complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnh cyclin H part_of IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000002
(PMID:23393140), (PMID:8692841) 		GO_Central
InterPro
RGD		 PMID:8692841 PMID:23393140 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:17,570,449...17,591,078
Ensembl chr 2:17,570,263...17,614,860 		JBrowse link
G Cdk7 cyclin-dependent kinase 7 part_of IEA
ISO
IBA 		GO_REF:0000107
(PMID:23393140), (PMID:8692841)
GO_REF:0000033
GO_REF:0000002 		Ensembl
RGD
GO_Central
InterPro		 PMID:8692841 PMID:23393140 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485 		JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase part_of ISO
IEA 		(PMID:8692841)
GO_REF:0000107 		RGD
Ensembl		 PMID:8692841 GO_REF:0000107 NCBI chr 6:97,550,566...97,706,598
Ensembl chr 6:97,550,543...97,706,595 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21544
    protein-containing complex 6918
      nuclear protein-containing complex 1363
        nuclear cyclin-dependent protein kinase holoenzyme complex 26
          CKM complex 4
          cyclin/CDK positive transcription elongation factor complex + 9
          transcription factor TFIIH holo complex + 12
Path 2
Term Annotations click to browse term
  cellular_component 21544
    protein-containing complex 6918
      catalytic complex 2002
        transferase complex 1048
          transferase complex, transferring phosphorus-containing groups 294
            protein kinase complex 137
              serine/threonine protein kinase complex 123
                cyclin-dependent protein kinase holoenzyme complex 64
                  nuclear cyclin-dependent protein kinase holoenzyme complex 26
                    CKM complex 4
                    cyclin/CDK positive transcription elongation factor complex + 9
                    transcription factor TFIIH holo complex + 12
paths to the root