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ONTOLOGY REPORT - ANNOTATIONS

Term:antigen processing and presentation of endogenous antigen
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Accession:GO:0019883 term browser browse the term
Definition:The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.
Synonyms:exact_synonym: antigen presentation, endogenous antigen


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antigen processing and presentation of endogenous antigen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG5 autophagy related 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107
G DLA-DOB major histocompatibility complex, class II, DO beta involved_in IEA InterPro GO_REF:0000002 NCBI chr12:2,376,957...2,384,179
Ensembl chr12:2,378,126...2,432,303 		JBrowse link
G IDE insulin degrading enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:6,844,480...6,967,713
Ensembl chr28:6,844,055...6,967,713 		JBrowse link
G PSMB8 proteasome 20S subunit beta 8 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:2,419,456...2,422,832
Ensembl chr12:2,378,126...2,432,303 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr12:2,424,049...2,432,165
Ensembl chr12:2,378,126...2,432,303 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:1758495 MGI
Ensembl
InterPro		 PMID:1758495 GO_REF:0000002 GO_REF:0000107 RGD:1299069 NCBI chr12:2,407,512...2,417,469
Ensembl chr12:2,378,126...2,432,303 		JBrowse link
G TAPBP TAP binding protein involved_in IEA InterPro GO_REF:0000002 NCBI chr12:2,740,276...2,751,808
Ensembl chr12:2,740,276...2,751,808 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TAP2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:2,407,512...2,417,469
Ensembl chr12:2,378,126...2,432,303 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZGP1 alpha-2-glycoprotein 1, zinc-binding involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:9,622,991...9,629,154
Ensembl chr 6:9,622,992...9,629,154 		JBrowse link
G DLA-12 MHC class I DLA-12 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:933,321...936,671
Ensembl chr12:932,613...987,561 		JBrowse link
G DLA-64 MHC class I DLA-64 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:983,573...986,969 JBrowse link
G DLA-79 MHC class Ib involved_in IBA GO_Central GO_REF:0000033 NCBI chr18:41,142,312...41,170,018
Ensembl chr18:41,142,307...41,170,100 		JBrowse link
G DLA88 MHC class I DLA-88 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:892,442...895,691
Ensembl chr12:892,388...1,021,690 		JBrowse link
G LOC100683099 UL16-binding protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:40,635,616...40,639,865 JBrowse link
G LOC119876868 DLA class I histocompatibility antigen, A9/A9 alpha chain-like involved_in IBA GO_Central GO_REF:0000033
antigen processing and presentation of endogenous peptide antigen via MHC class Ib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZGP1 alpha-2-glycoprotein 1, zinc-binding involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:9,622,991...9,629,154
Ensembl chr 6:9,622,992...9,629,154 		JBrowse link
G DLA-12 MHC class I DLA-12 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:933,321...936,671
Ensembl chr12:932,613...987,561 		JBrowse link
G DLA-64 MHC class I DLA-64 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:983,573...986,969 JBrowse link
G DLA-79 MHC class Ib involved_in IBA GO_Central GO_REF:0000033 NCBI chr18:41,142,312...41,170,018
Ensembl chr18:41,142,307...41,170,100 		JBrowse link
G DLA88 MHC class I DLA-88 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:892,442...895,691
Ensembl chr12:892,388...1,021,690 		JBrowse link
G LOC100683099 UL16-binding protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:40,635,616...40,639,865 JBrowse link
G LOC119876868 DLA class I histocompatibility antigen, A9/A9 alpha chain-like involved_in IBA GO_Central GO_REF:0000033
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TAP2 transporter 2, ATP binding cassette subfamily B member involved_in
acts_upstream_of_or_within		 IEA Ensembl GO_REF:0000107 NCBI chr12:2,407,512...2,417,469
Ensembl chr12:2,378,126...2,432,303 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLA-DRA MHC class II DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975 		JBrowse link
G DLA-DRB1 MHC class II DLA DRB1 beta chain involved_in ISO (PMID:15322540) UniProt PMID:15322540 NCBI chr12:2,151,409...2,164,564 JBrowse link
antigen processing and presentation, endogenous lipid antigen via MHC class Ib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1B CD1b molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr38:23,316,203...23,319,767 JBrowse link
G CD1C CD1c molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr38:23,328,183...23,331,270
Ensembl chr38:23,295,128...23,331,613 		JBrowse link
G CD1D CD1d molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr38:23,489,169...23,491,712 JBrowse link
G CD1E CD1e molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr38:23,295,037...23,298,004 JBrowse link
G LOC608848 T-cell surface glycoprotein CD1a involved_in IBA GO_Central GO_REF:0000033 NCBI chr38:23,454,227...23,457,720 JBrowse link
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    immune system process 2645
      antigen processing and presentation 102
        antigen processing and presentation of endogenous antigen 24
          antigen processing and presentation of endogenous peptide antigen + 18
          antigen processing and presentation, endogenous lipid antigen via MHC class Ib 5
paths to the root