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ONTOLOGY REPORT - ANNOTATIONS

Term:secondary metabolic process
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Accession:GO:0019748 term browser browse the term
Definition:The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
Synonyms:exact_synonym: secondary metabolism;   secondary metabolite metabolic process;   secondary metabolite metabolism
 xref: Wikipedia:Secondary_metabolism


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secondary metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
aflatoxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr7a3 aldo-keto reductase family 7 member A3 involved_in IMP
IDA
ISO		 PMID:10383892
(PMID:10383892)		 RGD PMID:10383892 PMID:12727802 PMID:10383892 RGD:1304380, RGD:598092476 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 IMP RGD PMID:27071940 RGD:12910550 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
aflatoxin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IEP RGD PMID:28959666 RGD:401794432 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 IDA RGD PMID:8234296 RGD:632009 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A IEP RGD PMID:28959666 RGD:401794432 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 involved_in ISO
IEA		 (PMID:16551781)
GO_REF:0000107		 RGD
Ensembl		 PMID:16551781 GO_REF:0000107 NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421 		JBrowse link
G Lcat lecithin cholesterol acyltransferase IEP RGD PMID:28959666 RGD:401794432 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lipc lipase C, hepatic type IEP RGD PMID:28959666 RGD:401794432 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 IEP RGD PMID:28959666 RGD:401794432 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
benzylpenicillin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 IMP RGD PMID:19255943 RGD:11081014 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
coumarin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C IDA RGD PMID:15502008 RGD:2317077 NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 IDA RGD PMID:15502008 RGD:2317077 NCBI chr 9:88,727,094...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
coumarin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA Coumarin derivative metabolism RGD PMID:11780761 RGD:2306676 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12162851 GO_REF:0000033, RGD:727640 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO (PMID:19438707) RGD PMID:19438707 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
daunorubicin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in ISO
IEA		 (PMID:18276838)
GO_REF:0000107		 RGD
Ensembl		 PMID:18276838 GO_REF:0000107 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in ISO (PMID:20837989) RGD PMID:20837989 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 involved_in ISO (PMID:20837989) RGD PMID:20837989 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in ISO
IBA		 (PMID:20837989)
GO_REF:0000033		 RGD
GO_Central		 PMID:20837989 GO_REF:0000033 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c12 aldo-keto reductase family 1, member C12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,045,376...66,061,496
Ensembl chr17:66,045,378...66,108,329 		JBrowse link
G Akr1c12l1 aldo-keto reductase family 1, member C12-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,937,834...65,948,344
Ensembl chr17:65,937,814...65,997,595
Ensembl chr17:65,937,814...65,997,595 		JBrowse link
G Akr1c13 aldo-keto reductase family 1, member C13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,964,186...65,997,598
Ensembl chr17:65,964,975...65,997,591 		JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277 		JBrowse link
G Akr1c19 aldo-keto reductase family 1, member C19 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,001,358...66,027,226
Ensembl chr17:66,004,002...66,025,047 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 involved_in ISO
IBA		 (PMID:20837989)
GO_REF:0000033		 RGD
GO_Central		 PMID:20837989 GO_REF:0000033 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO
IBA		 (PMID:20837989)
GO_REF:0000033		 RGD
GO_Central		 PMID:20837989 GO_REF:0000033 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akr1c3l1 aldo-keto reductase family 1 member C3-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 involved_in ISO (PMID:20837989) RGD PMID:20837989 NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:151,552,343...151,560,909 		JBrowse link
G Cbr4 carbonyl reductase 4 involved_in ISO
IEA		 (PMID:20837989)
GO_REF:0000107		 RGD
Ensembl		 PMID:20837989 GO_REF:0000107 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G ENSRNOG00000063788 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr17:65,937,814...65,948,421 JBrowse link
doxorubicin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in ISO
IEA		 (PMID:18276838)
GO_REF:0000107		 RGD
Ensembl		 PMID:18276838 GO_REF:0000107 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in ISO (PMID:20837989) RGD PMID:20837989 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 involved_in ISO (PMID:20837989) RGD PMID:20837989 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in ISO
IBA		 (PMID:20837989)
GO_REF:0000033		 RGD
GO_Central		 PMID:20837989 GO_REF:0000033 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c12 aldo-keto reductase family 1, member C12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,045,376...66,061,496
Ensembl chr17:66,045,378...66,108,329 		JBrowse link
G Akr1c12l1 aldo-keto reductase family 1, member C12-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,937,834...65,948,344
Ensembl chr17:65,937,814...65,997,595
Ensembl chr17:65,937,814...65,997,595 		JBrowse link
G Akr1c13 aldo-keto reductase family 1, member C13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,964,186...65,997,598
Ensembl chr17:65,964,975...65,997,591 		JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277 		JBrowse link
G Akr1c19 aldo-keto reductase family 1, member C19 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,001,358...66,027,226
Ensembl chr17:66,004,002...66,025,047 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 involved_in ISO
IBA		 (PMID:20837989)
GO_REF:0000033		 RGD
GO_Central		 PMID:20837989 GO_REF:0000033 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO
IBA		 (PMID:20837989)
GO_REF:0000033		 RGD
GO_Central		 PMID:20837989 GO_REF:0000033 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akr1c3l1 aldo-keto reductase family 1 member C3-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 involved_in ISO (PMID:20837989) RGD PMID:20837989 NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:151,552,343...151,560,909 		JBrowse link
G Cbr4 carbonyl reductase 4 involved_in ISO
IEA		 (PMID:20837989)
GO_REF:0000107		 RGD
Ensembl		 PMID:20837989 GO_REF:0000107 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G ENSRNOG00000063788 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr17:65,937,814...65,948,421 JBrowse link
insecticide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA Deltamethrin (pyrethroid) RGD PMID:16169030 RGD:2306660 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asip agouti signaling protein involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:8449404)
MGI:1855937 (PMID:7665913)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:7665913 PMID:8449404 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171 		JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11434569)		 UniProt
RGD		 PMID:11434569 GO_REF:0000024 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162 		JBrowse link
G Dct dopachrome tautomerase acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1856379 (PMID:7665913)
GO_REF:0000043
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:7665913 GO_REF:0000043 GO_REF:0000107 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Ddt D-dopachrome tautomerase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482 		JBrowse link
G Mc1r melanocortin 1 receptor acts_upstream_of_or_within ISO
IEA		 MGI:1856028 (PMID:7665913)
GO_REF:0000107		 RGD
Ensembl		 PMID:7665913 GO_REF:0000107 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO MGI:1856004 (PMID:7665913) RGD PMID:7665913 NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 MGI:1856114 (PMID:7665913), (PMID:9548375)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:7665913 PMID:9548375 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Pmel premelanosome protein acts_upstream_of_or_within ISO
IEA		 MGI:1857040 (PMID:7665913)
GO_REF:0000107		 RGD
Ensembl		 PMID:7665913 GO_REF:0000107 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of ISO
IEA		 (PMID:18166528)
GO_REF:0000107		 RGD
Ensembl		 PMID:18166528 GO_REF:0000107 NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:8126111)		 Ensembl
RGD		 PMID:8126111 GO_REF:0000107 NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276 		JBrowse link
G Tyr tyrosinase involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:8126111)
GO_REF:0000043
GO_REF:0000107
MGI:1855976|MGI:1855978 (PMID:7665913), (PMID:9548375)
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:7665913 PMID:8126111 PMID:9548375 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase involved_in ISO
IEA
IBA		 (PMID:2169885), (PMID:33100333)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:2169885 PMID:33100333 GO_REF:0000033 GO_REF:0000107 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO
IEA		 (PMID:25513726), (PMID:32966160)
GO_REF:0000107		 RGD
Ensembl		 PMID:25513726 PMID:32966160 GO_REF:0000107 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in ISO
IEA		 (PMID:32966160)
GO_REF:0000107
(PMID:35469906)		 RGD
Ensembl		 PMID:32966160 PMID:35469906 GO_REF:0000107 NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317 		JBrowse link
melanin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:2156165 (PMID:11709185) RGD PMID:11709185 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO MGI:1856004 (PMID:9548375) RGD PMID:9548375 NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:1855960 (PMID:9548375)
GO_REF:0000107		 RGD
Ensembl		 PMID:9548375 GO_REF:0000107 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO
IEA		 MGI:2136645 (PMID:22627278)
GO_REF:0000107		 RGD
Ensembl		 PMID:22627278 GO_REF:0000107 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO
IEA		 (PMID:29025994)
GO_REF:0000107		 RGD
Ensembl		 PMID:29025994 GO_REF:0000107 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988 		JBrowse link
G Opn3 opsin 3 involved_in ISO
IEA		 (PMID:31097585)
GO_REF:0000107		 RGD
Ensembl		 PMID:31097585 GO_REF:0000107 NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16272156)		 UniProt
RGD		 PMID:16272156 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO
IEA		 (PMID:18166528)
GO_REF:0000107		 RGD
Ensembl		 PMID:18166528 GO_REF:0000107 NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231 		JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:23569434)		 Ensembl
RGD		 PMID:23569434 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
phytoalexin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase IEP scoparone RGD PMID:19185027 RGD:5128879 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Th tyrosine hydroxylase IEP scoparone RGD PMID:19185027 RGD:5128879 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:21291857) RGD PMID:21291857 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Asip agouti signaling protein involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P07147|UniProtKB:Q60696 (PMID:21949658)		 Ensembl
RGD		 PMID:21949658 GO_REF:0000107 NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171 		JBrowse link
G Atp7a ATPase copper transporting alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:11092760)		 UniProt
RGD		 PMID:11092760 GO_REF:0000024 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:23334344) RGD PMID:23334344 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21291857)		 UniProt
Ensembl
RGD		 PMID:21291857 GO_REF:0000024 GO_REF:0000107 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Opn3 opsin 3 involved_in ISO
IEA		 (PMID:28842328)
GO_REF:0000107		 RGD
Ensembl		 PMID:28842328 GO_REF:0000107 NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847 		JBrowse link
G Pmel premelanosome protein involved_in ISO
IEA		 (PMID:21949658)
GO_REF:0000107		 RGD
Ensembl		 PMID:21949658 GO_REF:0000107 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746 		JBrowse link
G Rab38 RAB38, member RAS oncogene family IMP RGD PMID:17043139 RGD:152025192 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in ISO
IEA		 (PMID:21996312)
GO_REF:0000107
UniProtKB:Q03288|UniProtKB:Q60696 (PMID:21949658)		 RGD
Ensembl		 PMID:21949658 PMID:21996312 GO_REF:0000107 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter involved_in ISO (PMID:22649030) RGD PMID:22649030 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO
IEA
IBA		 (PMID:33208952)
GO_REF:0000107
GO_REF:0000033
(PMID:31117290)		 RGD
Ensembl
GO_Central		 PMID:31117290 PMID:33208952 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (PMID:16037214) RGD PMID:16037214 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
siderophore biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdh2 3-hydroxybutyrate dehydrogenase 2 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:20550936)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:20550936 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072 		JBrowse link
toxin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO
IEA		 (PMID:11511187)
GO_REF:0000107		 RGD
Ensembl		 PMID:11511187 GO_REF:0000107 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
toxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkce protein kinase C, epsilon acts_upstream_of ISO
IEA		 (PMID:18556656)
GO_REF:0000107		 RGD
Ensembl		 PMID:18556656 GO_REF:0000107 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
toxin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl1 ARF like GTPase 1 involved_in ISO
IEA
ISS		 (PMID:9624189)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9624189 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898 		JBrowse link
G As3mt arsenite methyltransferase involved_in IEA
IBA
IDA
ISO		 GO_REF:0000107
GO_REF:0000033
PMID:11790780
(PMID:25997655)		 Ensembl
GO_Central
RGD		 PMID:25997655 PMID:11790780 GO_REF:0000033 GO_REF:0000107, RGD:625365 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO
IEA		 MGI:2182307 (PMID:17166882)
GO_REF:0000107		 RGD
Ensembl		 PMID:17166882 GO_REF:0000107 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 acts_upstream_of_or_within ISO
IEA		 MGI:2182351 (PMID:17166882)
GO_REF:0000107		 RGD
Ensembl		 PMID:17166882 GO_REF:0000107 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 acts_upstream_of_or_within ISO
IEA		 MGI:2154690 (PMID:10051580), (PMID:17166882)
GO_REF:0000107		 RGD
Ensembl		 PMID:10051580 PMID:17166882 GO_REF:0000107 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 involved_in ISO
IEA		 (PMID:15144220)
GO_REF:0000107		 RGD
Ensembl		 PMID:15144220 GO_REF:0000107 NCBI chr13:77,715,405...77,747,666
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in ISO
IEA		 (PMID:11744609)
GO_REF:0000107		 RGD
Ensembl		 PMID:11744609 GO_REF:0000107 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 involved_in ISO (PMID:25997655) RGD PMID:25997655 NCBI chr11:26,584,750...26,597,790
Ensembl chr11:26,584,724...26,608,248 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase IDA enhances lethality of scorpion neurotoxin BmK ITa1 RGD PMID:12721493 RGD:6483565 NCBI chr 9:105,445,812...105,719,287
Ensembl chr 9:98,122,916...98,271,965 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        secondary metabolic process 71
          (+)-kotanin metabolic process + 0
          (17Z)-protosta-17(20),24-dien-3beta-ol metabolic process + 0
          N',N'',N'''-triacetylfusarinine C metabolic process + 0
          arugosin metabolic process + 0
          asperthecin metabolic process + 0
          cordyol C metabolic process + 0
          cspyrone B1 metabolic process + 0
          cyanogenic glycoside metabolic process + 0
          dehydroaustinol metabolic process + 0
          demethylkotanin metabolic process + 0
          diorcinol metabolic process + 0
          emericellamide metabolic process + 0
          emericellin metabolic process + 0
          emodin metabolic process + 0
          endocrocin metabolic process + 0
          ergot alkaloid metabolic process + 0
          fumagillin biosynthetic process + 0
          fumonisin metabolic process + 0
          gerfelin metabolic process + 0
          helvolic acid metabolic process + 0
          melanin metabolic process + 26
          monodictyphenone metabolic process + 0
          o-orsellinic acid metabolic process + 0
          ocellus pigment metabolic process + 0
          ochratoxin A metabolic process + 0
          orcinol metabolic process + 0
          orlandin metabolic process + 0
          penicillin metabolic process + 1
          phenylpropanoid metabolic process + 8
          pheromone metabolic process + 0
          phytochelatin metabolic process + 0
          polyketide metabolic process + 15
          regulation of secondary metabolic process + 15
          secondary metabolite biosynthetic process + 26
          secondary metabolite catabolic process + 0
          shamixanthone metabolic process + 0
          siderophore metabolic process + 1
          tensidol A metabolic process + 0
          tensidol B metabolic process + 0
          toxin metabolic process + 20
          violaceol I metabolic process + 0
          violaceol II metabolic process + 0
paths to the root