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ONTOLOGY REPORT - ANNOTATIONS

Term:antimicrobial humoral response
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Accession:GO:0019730 term browser browse the term
Definition:An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
Synonyms:alt_id: GO:0006960;   GO:0019735
 xref: Reactome:R-HSA-6803157 "Antimicrobial peptides"

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antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3 transcription coactivator acts_upstream_of_or_within ISO (PMID:9009202) MGI PMID:9009202 NCBI chrNW_004955555:1,898,280...1,911,466
Ensembl chrNW_004955555:1,856,250...1,911,466 		JBrowse link
G Colec11 collectin subfamily member 11 involved_in ISO (PMID:20956340) UniProt PMID:20956340 NCBI chrNW_004955487:3,778,901...3,789,852
Ensembl chrNW_004955487:3,778,858...3,790,080 		JBrowse link
antibacterial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO PMID:20209079 UniProt PMID:20209079 RGD:10400853 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Bpifa1 BPI fold containing family A member 1 involved_in ISO (PMID:23499554) UniProt PMID:23499554 NCBI chrNW_004955422:28,063,077...28,069,939 JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:1599934), (PMID:18714013) UniProt PMID:1599934 PMID:18714013 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO (PMID:18714013) UniProt PMID:18714013 NCBI chrNW_004955413:24,431,592...24,482,229
Ensembl chrNW_004955413:24,429,589...24,482,537 		JBrowse link
G Rnase6 ribonuclease A family member 6 involved_in ISO (PMID:25075772) UniProt PMID:25075772 NCBI chrNW_004955550:1,687,068...1,688,160 JBrowse link
G Rnase7 ribonuclease A family member 7 involved_in ISO (PMID:25075772) UniProt PMID:25075772 NCBI chrNW_004955550:1,796,301...1,797,801 JBrowse link
antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals4 galectin 4 acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955468:694,831...701,623
Ensembl chrNW_004955468:694,873...701,535 		JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:20056603) MGI PMID:20056603 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
antibacterial peptide secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:11248802) MGI PMID:11248802 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
antifungal humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO PMID:20209079 UniProt PMID:20209079 RGD:10400853 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G Il36rn interleukin 36 receptor antagonist involved_in ISO (PMID:23147407) UniProt PMID:23147407 NCBI chrNW_004955470:1,209,389...1,214,730
Ensembl chrNW_004955470:1,209,325...1,214,821 		JBrowse link
antimicrobial humoral immune response mediated by antimicrobial peptide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10225288) UniProt PMID:10225288 NCBI chrNW_004955414:25,951,473...25,953,593
Ensembl chrNW_004955414:25,951,349...25,953,645 		JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:20209079) UniProt PMID:20209079 RGD:10400853 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268 		JBrowse link
G B2m beta-2-microglobulin involved_in ISO (PMID:23144825) UniProt PMID:23144825 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Bpifa1 BPI fold containing family A member 1 involved_in ISO (PMID:21805676) UniProt PMID:21805676 NCBI chrNW_004955422:28,063,077...28,069,939 JBrowse link
G Camp cathelicidin antimicrobial peptide involved_in ISO (PMID:17012259)
(PMID:12759353), (PMID:12860195), (PMID:14978112), (PMID:20209079), (PMID:20421939), (PMID:23537644), (PMID:7529412), (PMID:9182550) 		UniProt PMID:7529412 PMID:9182550 PMID:12759353 PMID:12860195 PMID:14978112 More... NCBI chrNW_004955420:24,911,920...24,914,698 JBrowse link
G Ccl1 C-C motif chemokine ligand 1 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955481:9,085,943...9,089,147 JBrowse link
G Ccl17 C-C motif chemokine ligand 17 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:15,052,616...15,054,732
Ensembl chrNW_004955433:15,053,061...15,054,572 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955472:1,444,598...1,446,488
Ensembl chrNW_004955472:1,444,316...1,446,490 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 involved_in ISO (PMID:12949249), (PMID:19109182) UniProt PMID:12949249 PMID:19109182 NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955472:1,427,660...1,428,771
Ensembl chrNW_004955472:1,427,710...1,429,102 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:15,002,001...15,007,324
Ensembl chrNW_004955433:15,001,930...15,008,032 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955563:1,249,098...1,255,469 JBrowse link
G Ccl27 C-C motif chemokine ligand 27 involved_in ISO (PMID:19109182) UniProt PMID:19109182 NCBI chrNW_004955472:1,470,407...1,474,800
Ensembl chrNW_004955472:1,471,551...1,474,777 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 involved_in ISO (PMID:12538707) UniProt PMID:12538707 NCBI chrNW_004955446:18,902,465...18,925,178
Ensembl chrNW_004955446:18,902,636...18,925,561 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:769,449...771,137
Ensembl chrNW_004955433:766,272...771,231 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955546:1,929,269...1,941,690
Ensembl chrNW_004955546:1,929,269...1,941,690 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:2,123,190...2,129,119 JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 involved_in ISO (PMID:12949249), (PMID:19109182)
(PMID:19109182) 		UniProt PMID:12949249 PMID:19109182 NCBI chrNW_004955408:30,733,079...30,740,854
Ensembl chrNW_004955408:30,733,079...30,740,854 		JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 involved_in ISO (PMID:19109182) UniProt PMID:19109182 NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955433:724,566...731,945
Ensembl chrNW_004955433:724,515...732,192 		JBrowse link
G Dcd dermcidin involved_in ISO (PMID:11694882) UniProt PMID:11694882 NCBI chrNW_004955458:1,875,244...1,879,434 JBrowse link
G Defb118 defensin beta 118 involved_in ISO (PMID:15033915) UniProt PMID:15033915 NCBI chrNW_004955422:29,554,310...29,560,660 JBrowse link
G Defb127 defensin beta 127 involved_in ISO (PMID:19373462) UniProt PMID:19373462 NCBI chrNW_004955597:38,613...40,241 JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 involved_in ISO (PMID:11007786) UniProt PMID:11007786 NCBI chrNW_004955477:863,388...899,703 JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO (PMID:20421939) UniProt PMID:20421939 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517 		JBrowse link
G Fam3a FAM3 metabolism regulating signaling molecule A involved_in ISO (PMID:18212107) UniProt PMID:18212107 NCBI chrNW_004955580:1,025,481...1,036,752
Ensembl chrNW_004955580:1,029,553...1,036,849 		JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion involved_in ISO (PMID:12860195)
(PMID:10496312) 		UniProt PMID:10496312 PMID:12860195 NCBI chrNW_004955422:20,078,393...20,080,855
Ensembl chrNW_004955422:20,078,393...20,080,855 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:22832495) UniProt PMID:22832495 NCBI chrNW_004955413:4,162,467...4,166,783
Ensembl chrNW_004955413:4,162,467...4,166,783 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:11034317), (PMID:11113131) UniProt PMID:11034317 PMID:11113131 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649 		JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 involved_in ISO (PMID:16204630) UniProt PMID:16204630 NCBI chrNW_004955452:5,846,085...5,849,996
Ensembl chrNW_004955452:5,846,085...5,849,996 		JBrowse link
G Hrg histidine rich glycoprotein involved_in ISO (PMID:18797515) UniProt PMID:18797515 NCBI chrNW_004955420:21,020,938...21,033,022
Ensembl chrNW_004955420:21,019,212...21,032,976 		JBrowse link
G Krt6a keratin 6A involved_in ISO (PMID:23006328) UniProt PMID:23006328 NCBI chrNW_004955547:2,902,962...2,907,670 JBrowse link
G Leap2 liver enriched antimicrobial peptide 2 involved_in ISO (PMID:12493837) UniProt PMID:12493837 NCBI chrNW_004955408:4,245,574...4,247,117
Ensembl chrNW_004955408:4,245,574...4,247,117 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (PMID:16982911) UniProt PMID:16982911 NCBI chrNW_004955409:8,448,120...8,452,437
Ensembl chrNW_004955409:8,447,774...8,452,438 		JBrowse link
G LOC102004444 beta-defensin 1-like involved_in ISO (PMID:25122636)
(PMID:12860195) 		UniProt PMID:12860195 PMID:25122636 NCBI chrNW_004955403:53,643,328...53,644,361
Ensembl chrNW_004955403:53,643,300...53,644,505 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:15155221) UniProt PMID:15155221 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331 		JBrowse link
G Muc7 mucin 7, secreted involved_in ISO (PMID:12543672) UniProt PMID:12543672 NCBI chrNW_004955447:2,511,841...2,520,312 JBrowse link
G Nppb natriuretic peptide B involved_in ISO (PMID:11410403) UniProt PMID:11410403 NCBI chrNW_004955486:2,054,775...2,056,130 JBrowse link
G Npy neuropeptide Y involved_in ISO (PMID:18603306) UniProt PMID:18603306 NCBI chrNW_004955410:26,348,388...26,355,232
Ensembl chrNW_004955410:26,348,504...26,355,297 		JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 involved_in ISO (PMID:16354652) UniProt PMID:16354652 NCBI chrNW_004955574:424,046...427,675
Ensembl chrNW_004955574:424,142...427,540 		JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 involved_in ISO (PMID:16354652) UniProt PMID:16354652 NCBI chrNW_004955592:100,022...111,609
Ensembl chrNW_004955592:100,088...111,610 		JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISO (PMID:12860195) UniProt PMID:12860195 NCBI chrNW_004955455:11,308,848...11,316,245
Ensembl chrNW_004955455:11,308,643...11,316,254 		JBrowse link
G Rnase6 ribonuclease A family member 6 involved_in ISO (PMID:25075772) UniProt PMID:25075772 NCBI chrNW_004955550:1,687,068...1,688,160 JBrowse link
G Rnase7 ribonuclease A family member 7 involved_in ISO (PMID:12244054), (PMID:23302724), (PMID:25075772) GO_Central PMID:12244054 PMID:23302724 PMID:25075772 NCBI chrNW_004955550:1,796,301...1,797,801 JBrowse link
G Romo1 reactive oxygen species modulator 1 involved_in ISO (PMID:22083756) UniProt PMID:22083756 NCBI chrNW_004955422:25,757,558...25,760,054
Ensembl chrNW_004955422:25,757,558...25,759,769 		JBrowse link
G Rpl30 ribosomal protein L30 involved_in ISO (PMID:15019208) UniProt PMID:15019208 NCBI chrNW_004955417:13,764,814...13,767,698
Ensembl chrNW_004955417:13,764,814...13,767,698 		JBrowse link
G Rpl39 ribosomal protein L39 involved_in ISO (PMID:12860195) UniProt PMID:12860195 NCBI chrNW_004955534:200,591...203,827 JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15019208) UniProt PMID:15019208 NCBI chrNW_004955555:969,345...976,122
Ensembl chrNW_004955555:969,340...976,509 		JBrowse link
G Tac1 tachykinin precursor 1 involved_in ISO (PMID:18603306) UniProt PMID:18603306 NCBI chrNW_004955432:13,991,647...13,999,665
Ensembl chrNW_004955432:13,991,414...13,999,728 		JBrowse link
G Tslp thymic stromal lymphopoietin involved_in ISO (PMID:24850429) UniProt PMID:24850429 NCBI chrNW_004955418:4,041,529...4,045,534 JBrowse link
G Vip vasoactive intestinal peptide involved_in ISO (PMID:18603306) UniProt PMID:18603306 NCBI chrNW_004955439:9,021,923...9,031,783
Ensembl chrNW_004955439:9,021,904...9,031,792 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:12949249) UniProt PMID:12949249 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
induction of bacterial agglutination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fga fibrinogen alpha chain involved_in ISO (PMID:24367264) CACAO PMID:24367264 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:24367264) CACAO PMID:24367264 NCBI chrNW_004955471:8,824,901...8,832,836
Ensembl chrNW_004955471:8,822,965...8,832,884 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO (PMID:14691481) MGI PMID:14691481 NCBI chrNW_004955514:598,840...603,390
Ensembl chrNW_004955514:596,829...604,051 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk5 kallikrein related peptidase 5 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chrNW_004955558:1,512,478...1,520,522
Ensembl chrNW_004955558:1,511,818...1,520,613 		JBrowse link
G Klk7 kallikrein related peptidase 7 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chrNW_004955558:1,490,884...1,494,843
Ensembl chrNW_004955558:1,490,120...1,494,993 		JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) UniProt PMID:12759353 NCBI chrNW_004955437:8,142,523...8,153,044
Ensembl chrNW_004955437:8,142,661...8,151,339 		JBrowse link
positive regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23610393) UniProt PMID:23610393 NCBI chrNW_004955404:30,254,934...30,266,898
Ensembl chrNW_004955404:30,254,841...30,270,921 		JBrowse link
G Camp cathelicidin antimicrobial peptide ISO RGD PMID:18227173 RGD:438738460 NCBI chrNW_004955420:24,911,920...24,914,698 JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962 		JBrowse link
G Il17f interleukin 17F involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004955411:5,852,767...5,859,208
Ensembl chrNW_004955411:5,852,767...5,859,208 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955506:6,227,488...6,246,339
Ensembl chrNW_004955506:6,227,673...6,246,138 		JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955592:522,730...525,728 JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955442:12,581,918...12,627,407
Ensembl chrNW_004955442:12,581,879...12,626,516 		JBrowse link
regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp2r3c protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within ISO (PMID:16129705) MGI PMID:16129705 NCBI chrNW_004955409:25,920,973...25,943,985 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12627
    immune system process 2049
      immune response 1227
        humoral immune response 141
          antimicrobial humoral response 73
            antibacterial humoral response + 18
            antifungal humoral response + 2
            antimicrobial humoral immune response mediated by antimicrobial peptide + 64
            negative regulation of antimicrobial humoral response + 0
            positive regulation of antimicrobial humoral response + 8
            regulation of antimicrobial humoral response + 12
Path 2
Term Annotations click to browse term
  biological_process 12627
    response to stimulus 6840
      response to biotic stimulus 1345
        response to external biotic stimulus 1298
          response to other organism 1295
            defense response to other organism 728
              defense response to symbiont 707
                antimicrobial humoral response 73
                  antibacterial humoral response + 18
                  antifungal humoral response + 2
                  antimicrobial humoral immune response mediated by antimicrobial peptide + 64
                  negative regulation of antimicrobial humoral response + 0
                  positive regulation of antimicrobial humoral response + 8
                  regulation of antimicrobial humoral response + 12
paths to the root