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ONTOLOGY REPORT - ANNOTATIONS

Term:triglyceride catabolic process
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Accession:GO:0019433 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
Synonyms:exact_synonym: triacylglycerol catabolic process;   triacylglycerol catabolism;   triglyceride breakdown;   triglyceride catabolism;   triglyceride degradation
 xref: MetaCyc:LIPAS-PWY;   Reactome:R-HSA-163560 "Triglyceride catabolism"

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triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,069,683...2,071,344
Ensembl chrNW_004936542:2,069,683...2,071,353 		JBrowse link
G Apob apolipoprotein B acts_upstream_of_or_within ISO
IEA 		RGD
Ensembl		 PMID:9290048 GO_REF:0000107 RGD:1626404 NCBI chrNW_004936493:10,509,118...10,549,144
Ensembl chrNW_004936493:10,509,118...10,549,144 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:11590213) Ensembl
MGI		 PMID:11590213 GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936586:5,739,038...5,850,317
Ensembl chrNW_004936586:5,739,337...5,850,312 		JBrowse link
G Ddhd2 DDHD domain containing 2 acts_upstream_of_or_within
involved_in 		IEA
ISO 		(PMID:25267624) Ensembl
MGI		 PMID:25267624 GO_REF:0000107 NCBI chrNW_004936710:1,593,899...1,616,572
Ensembl chrNW_004936710:1,593,946...1,618,828 		JBrowse link
G Fabp4 fatty acid binding protein 4 involved_in ISO (PMID:16188906), (PMID:38216738) MGI PMID:16188906 PMID:38216738 NCBI chrNW_004936656:2,722,970...2,727,383
Ensembl chrNW_004936656:2,722,713...2,729,046 		JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 involved_in ISO (PMID:30559189) ComplexPortal PMID:30559189 NCBI chrNW_004936470:8,798,095...8,800,176 JBrowse link
G Lipc lipase C, hepatic type involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:19,604,083...19,733,721
Ensembl chrNW_004936471:19,703,236...19,733,686 		JBrowse link
G Lipe lipase E, hormone sensitive type involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:11717312), (PMID:17074755)
(PMID:16804080) 		RGD
UniProt
TreeGrafter
MGI		 PMID:11717312 PMID:14739077 PMID:16804080 PMID:17074755 GO_REF:0000041 GO_REF:0000117 GO_REF:0000118 RGD:1581873 NCBI chrNW_004936706:122,939...139,506
Ensembl chrNW_004936706:128,133...141,276 		JBrowse link
G LOC101971765 pancreatic lipase-related protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936486:6,567,239...6,589,481
Ensembl chrNW_004936486:6,572,654...6,589,436 		JBrowse link
G Lpl lipoprotein lipase involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936555:4,084,099...4,108,219
Ensembl chrNW_004936555:4,084,099...4,108,365 		JBrowse link
G Mgll monoglyceride lipase involved_in ISO (PMID:21454566) MGI PMID:21454566 NCBI chrNW_004936798:681,549...721,645
Ensembl chrNW_004936798:681,380...724,463 		JBrowse link
G Plb1 phospholipase B1 involved_in ISO PMID:9442065
PMID:9442064 		UniProt PMID:9442064 PMID:9442065 RGD:30309923 RGD:633237 NCBI chrNW_004936493:4,112,632...4,210,882
Ensembl chrNW_004936493:4,112,858...4,232,492 		JBrowse link
G Pnpla1 patatin like domain 1, omega-hydroxyceramide transacylase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936476:23,066,840...23,100,126
Ensembl chrNW_004936476:23,061,854...23,099,720 		JBrowse link
G Pnpla2 patatin like domain 2, triacylglycerol lipase acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:17074755) MGI
Ensembl
TreeGrafter		 PMID:17074755 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936888:580,773...585,949
Ensembl chrNW_004936888:580,767...587,083 		JBrowse link
G Pnpla3 patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936718:1,620,034...1,638,315
Ensembl chrNW_004936718:1,619,948...1,638,317 		JBrowse link
G Pnpla4 patatin like domain 4, phospholipase and triacylglycerol lipase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936644:1,091,794...1,113,621
Ensembl chrNW_004936644:1,093,388...1,112,557 		JBrowse link
G Pnpla5 patatin like domain 5, triacylglycerol lipase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936718:1,568,339...1,577,701
Ensembl chrNW_004936718:1,568,339...1,577,701 		JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) ARUK-UCL PMID:15576844 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chrNW_004936671:780,173...827,628
Ensembl chrNW_004936671:782,135...827,771 		JBrowse link
G Pak4 p21 (RAC1) activated kinase 4 involved_in ISO (PMID:38216738) MGI PMID:38216738 NCBI chrNW_004936661:2,012,439...2,048,523
Ensembl chrNW_004936661:2,042,670...2,048,544 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chrNW_004936479:17,084,006...17,112,264
Ensembl chrNW_004936479:17,084,920...17,112,258 		JBrowse link
G Plin1 perilipin 1 involved_in ISO (PMID:15136565) MGI PMID:15136565 NCBI chrNW_004936483:15,457,299...15,470,674
Ensembl chrNW_004936483:15,457,297...15,470,350 		JBrowse link
G Plin5 perilipin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:2,629,762...2,637,303
Ensembl chrNW_004936588:2,629,762...2,636,983 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:6,192,407...6,352,835
Ensembl chrNW_004936542:6,192,407...6,352,424 		JBrowse link
positive regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase involved_in ISO (PMID:19654421) UniProt PMID:19654421 NCBI chrNW_004937349:52,605...62,840 JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936695:1,644,758...1,672,024
Ensembl chrNW_004936695:1,644,581...1,672,117 		JBrowse link
G Apoa4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,098,683...2,101,127
Ensembl chrNW_004936542:2,098,683...2,101,127 		JBrowse link
G Apoa5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,069,683...2,071,344
Ensembl chrNW_004936542:2,069,683...2,071,353 		JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:10727238) BHF-UCL PMID:10727238 NCBI chrNW_004936706:1,531,219...1,531,921 JBrowse link
G Apoh apolipoprotein H ISO RGD PMID:7078428 RGD:8554677 NCBI chrNW_004936541:6,683,483...6,695,094
Ensembl chrNW_004936541:6,683,534...6,695,066 		JBrowse link
G Daglb diacylglycerol lipase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936750:17,411...105,436
Ensembl chrNW_004936750:78,548...105,281 		JBrowse link
G Fgf21 fibroblast growth factor 21 ISO RGD PMID:23262585 RGD:10401916 NCBI chrNW_004936664:2,826,823...2,828,330
Ensembl chrNW_004936664:2,826,823...2,828,330 		JBrowse link
G Ldlr low density lipoprotein receptor ISO RGD PMID:28469073 RGD:12910100 NCBI chrNW_004936659:1,259,405...1,300,545
Ensembl chrNW_004936659:1,259,369...1,302,294 		JBrowse link
G Pnpla2 patatin like domain 2, triacylglycerol lipase involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chrNW_004936888:580,773...585,949
Ensembl chrNW_004936888:580,767...587,083 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:16595669)
(PMID:10634941) 		MGI PMID:10634941 PMID:16595669 NCBI chrNW_004936659:2,750,015...2,765,914
Ensembl chrNW_004936659:2,750,537...2,765,753 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23296834) AgBase PMID:23296834 NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17733
    cellular process 17274
      metabolic process 11561
        catabolic process 2551
          lipid catabolic process 330
            glycerolipid catabolic process 71
              acylglycerol catabolic process 47
                triglyceride catabolic process 35
                  negative regulation of triglyceride catabolic process 8
                  positive regulation of triglyceride catabolic process 12
                  regulation of triglyceride catabolic process + 20
Path 2
Term Annotations click to browse term
  biological_process 17733
    cellular process 17274
      metabolic process 11561
        primary metabolic process 10200
          lipid metabolic process 1329
            neutral lipid metabolic process 157
              acylglycerol metabolic process 155
                triglyceride metabolic process 128
                  triglyceride catabolic process 35
                    negative regulation of triglyceride catabolic process 8
                    positive regulation of triglyceride catabolic process 12
                    regulation of triglyceride catabolic process + 20
paths to the root