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ONTOLOGY REPORT - ANNOTATIONS

Term:triglyceride catabolic process
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Accession:GO:0019433 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
Synonyms:exact_synonym: triacylglycerol catabolic process;   triacylglycerol catabolism;   triglyceride breakdown;   triglyceride catabolism;   triglyceride degradation
 xref: MetaCyc:LIPAS-PWY;   Reactome:R-HSA-163560 "Triglyceride catabolism"

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triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,154,880...108,158,998
Ensembl chr 1:108,155,641...108,157,375 		JBrowse link
G APOB apolipoprotein B acts_upstream_of_or_within ISO
IEA 		RGD
Ensembl		 PMID:9290048 GO_REF:0000107 RGD:1626404 NCBI chr14:86,624,209...86,669,175
Ensembl chr14:86,624,332...86,668,704 		JBrowse link
G APOC3 apolipoprotein C3 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:11590213) MGI
Ensembl		 PMID:11590213 GO_REF:0000107 NCBI chr 1:108,196,283...108,199,274
Ensembl chr 1:108,196,939...108,199,342 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206 		JBrowse link
G DDHD2 DDHD domain containing 2 acts_upstream_of_or_within
involved_in 		IEA
ISO 		(PMID:25267624) Ensembl
MGI		 PMID:25267624 GO_REF:0000107 NCBI chr 8:36,246,966...36,278,543
Ensembl chr 8:36,247,114...36,275,899 		JBrowse link
G FABP4 fatty acid binding protein 4 involved_in ISO (PMID:16188906), (PMID:38216738) MGI PMID:16188906 PMID:38216738 NCBI chr 8:76,895,516...76,900,153
Ensembl chr 8:76,894,512...76,900,212 		JBrowse link
G GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:137,433,669...137,440,681
Ensembl chr 8:137,436,997...137,440,909 		JBrowse link
G LIPC lipase C, hepatic type involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:24,946,843...25,109,338
Ensembl chr26:24,946,673...25,087,921 		JBrowse link
G LIPE lipase E, hormone sensitive type involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:16804080)
(PMID:11717312), (PMID:17074755) 		RGD
UniProt
MGI
TreeGrafter		 PMID:11717312 PMID:14739077 PMID:16804080 PMID:17074755 GO_REF:0000041 GO_REF:0000118 RGD:1581873 NCBI chr 6:36,604,822...36,630,648
Ensembl chr 6:36,605,126...36,630,376 		JBrowse link
G LOC103216568 pancreatic lipase-related protein 2 involved_in ISO (PMID:23770034)
(PMID:15287741), (PMID:17401110) 		UniProt PMID:15287741 PMID:17401110 PMID:23770034 NCBI chr 9:109,428,235...109,453,687 JBrowse link
G LPL lipoprotein lipase involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr 8:18,009,049...18,038,315
Ensembl chr 8:18,009,093...18,038,598 		JBrowse link
G MGLL monoglyceride lipase involved_in ISO (PMID:21454566) MGI PMID:21454566 NCBI chr22:53,092,970...53,354,316
Ensembl chr22:53,218,672...53,354,448 		JBrowse link
G PLB1 phospholipase B1 involved_in ISO PMID:9442064
PMID:9442065 		UniProt PMID:9442064 PMID:9442065 RGD:30309923 RGD:633237 NCBI chr14:78,960,601...79,122,082
Ensembl chr14:78,960,202...79,096,555 		JBrowse link
G PNPLA1 patatin like domain 1, omega-hydroxyceramide transacylase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:35,808,652...35,854,069
Ensembl chr17:35,814,590...35,851,985 		JBrowse link
G PNPLA2 patatin like domain 2, triacylglycerol lipase acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:17074755) MGI
TreeGrafter
Ensembl		 PMID:17074755 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:626,060...631,556 JBrowse link
G PNPLA3 patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:26,435,302...26,458,368
Ensembl chr19:26,435,599...26,462,210 		JBrowse link
G PNPLA4 patatin like domain 4, phospholipase and triacylglycerol lipase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:6,247,971...6,396,168
Ensembl chr  X:6,363,541...6,394,704 		JBrowse link
G PNPLA5 patatin like domain 5, triacylglycerol lipase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:26,396,040...26,408,553
Ensembl chr19:26,397,163...26,408,126 		JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:38,386,190...38,387,159 JBrowse link
G APOC1 apolipoprotein C1 involved_in ISO (PMID:15576844) ARUK-UCL PMID:15576844
G APOC3 apolipoprotein C3 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:108,196,283...108,199,274
Ensembl chr 1:108,196,939...108,199,342 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chr17:47,748,183...47,809,459
Ensembl chr17:47,765,699...47,804,378 		JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 involved_in ISO (PMID:38216738) MGI PMID:38216738 NCBI chr 6:33,715,695...33,769,272
Ensembl chr 6:33,759,462...33,770,497 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chr21:75,781,812...75,823,404
Ensembl chr21:75,784,648...75,825,496 		JBrowse link
G PLIN1 perilipin 1 involved_in ISO (PMID:15136565) MGI PMID:15136565 NCBI chr29:8,204,071...8,219,974
Ensembl chr29:8,202,035...8,215,921 		JBrowse link
G PLIN5 perilipin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:4,251,316...4,262,656
Ensembl chr 6:4,251,751...4,261,126 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,877,052...113,062,167
Ensembl chr 1:112,877,151...113,058,050 		JBrowse link
positive regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAC arylacetamide deacetylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:38,855,753...38,870,748
Ensembl chr15:38,855,348...38,870,649 		JBrowse link
G ABHD5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:5,109,699...5,139,021
Ensembl chr22:5,109,765...5,137,673 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,186,627...108,190,508
Ensembl chr 1:108,186,921...108,189,698 		JBrowse link
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,154,880...108,158,998
Ensembl chr 1:108,155,641...108,157,375 		JBrowse link
G APOC2 apolipoprotein C2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,406,829...38,411,239
Ensembl chr 6:38,409,641...38,410,927 		JBrowse link
G APOH apolipoprotein H ISO RGD PMID:7078428 RGD:8554677 NCBI chr16:55,209,142...55,231,176 JBrowse link
G DAGLB diacylglycerol lipase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:15,616,744...15,660,829
Ensembl chr28:15,617,459...15,659,291 		JBrowse link
G FGF21 fibroblast growth factor 21 ISO RGD PMID:23262585 RGD:10401916 NCBI chr 6:42,006,125...42,008,749
Ensembl chr 6:42,006,064...42,008,736 		JBrowse link
G LDLR low density lipoprotein receptor ISO RGD PMID:28469073 RGD:12910100 NCBI chr 6:10,062,204...10,091,780
Ensembl chr 6:10,062,790...10,091,377 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:10634941)
(PMID:16595669) 		MGI PMID:10634941 PMID:16595669 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:23296834) AgBase PMID:23296834 NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19940
    cellular process 19399
      metabolic process 13170
        catabolic process 2699
          lipid catabolic process 367
            glycerolipid catabolic process 76
              acylglycerol catabolic process 49
                triglyceride catabolic process 36
                  negative regulation of triglyceride catabolic process 9
                  positive regulation of triglyceride catabolic process 11
                  regulation of triglyceride catabolic process + 20
Path 2
Term Annotations click to browse term
  biological_process 19940
    cellular process 19399
      metabolic process 13170
        primary metabolic process 11583
          lipid metabolic process 1417
            neutral lipid metabolic process 165
              acylglycerol metabolic process 164
                triglyceride metabolic process 135
                  triglyceride catabolic process 36
                    negative regulation of triglyceride catabolic process 9
                    positive regulation of triglyceride catabolic process 11
                    regulation of triglyceride catabolic process + 20
paths to the root