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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:triglyceride catabolic process
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Accession:GO:0019433 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
Synonyms:exact_synonym: triacylglycerol catabolic process;   triacylglycerol catabolism;   triglyceride breakdown;   triglyceride catabolism;   triglyceride degradation
 xref: MetaCyc:LIPAS-PWY;   Reactome:R-HSA-163560 "Triglyceride catabolism"



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triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 involved_in ISO (PMID:15178420) BHF-UCL PMID:15178420 NCBI chr 8:40,782,715...40,784,990 JBrowse link
G Apob apolipoprotein B acts_upstream_of_or_within ISO (PMID:16455790) MGI
RGD
PMID:9290048 PMID:16455790 RGD:1626404 NCBI chr 7:28,340,169...28,378,753 JBrowse link
G Apoc3 apolipoprotein C3 acts_upstream_of_or_within
involved_in
ISO (PMID:11590213)
(PMID:11060345)
MGI
BHF-UCL
PMID:11060345 PMID:11590213 NCBI chr 8:40,753,291...40,756,012 JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 involved_in ISO (PMID:9711878) BHF-UCL PMID:9711878 NCBI chr 4:139,655,447...139,743,127 JBrowse link
G Ddhd2 DDHD domain containing 2 acts_upstream_of_or_within
involved_in
ISO (PMID:25267624) MGI PMID:25267624 NCBI chr13:60,744,087...60,773,449 JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 involved_in ISO (PMID:30559189) ComplexPortal PMID:30559189 NCBI chr 1:247,921,739...247,923,328 JBrowse link
G Lipc lipase C, hepatic type involved_in ISO (PMID:182536), (PMID:2839510), (PMID:8640403) BHF-UCL PMID:182536 PMID:2839510 PMID:8640403 NCBI chr 8:65,155,676...65,281,061 JBrowse link
G Lipe lipase E, hormone sensitive type acts_upstream_of_or_within
involved_in
ISO (PMID:11717312), (PMID:17074755)
(PMID:16804080)
(PMID:16679289), (PMID:23066022)
RGD
MGI
PMID:11717312 PMID:14739077 PMID:16679289 PMID:16804080 PMID:17074755 More... RGD:1581873 NCBI chr 2:169,321,701...169,337,729 JBrowse link
G Lpl lipoprotein lipase involved_in ISO (PMID:15178420)
(PMID:11342582), (PMID:182536), (PMID:2110364), (PMID:2340307), (PMID:27578112), (PMID:30559189), (PMID:3973011)
BHF-UCL
ComplexPortal
PMID:182536 PMID:2110364 PMID:2340307 PMID:3973011 PMID:11342582 More... NCBI chr13:20,546,274...20,567,849 JBrowse link
G Mgll monoglyceride lipase involved_in ISO (PMID:21454566) MGI PMID:21454566 NCBI chr 6:57,502,268...57,603,999 JBrowse link
G Plb1 phospholipase B1 involved_in ISO PMID:9442064
PMID:9442065
UniProt PMID:9442064 PMID:9442065 RGD:30309923 RGD:633237 NCBI chr 7:21,800,126...21,901,051 JBrowse link
G Pnpla2 patatin like domain 2, triacylglycerol lipase involved_in
acts_upstream_of_or_within
ISO (PMID:16679289)
(PMID:16679289), (PMID:23066022)
(PMID:16675698)
(PMID:17074755)
UniProt
MGI
PMID:16675698 PMID:16679289 PMID:17074755 PMID:23066022 NCBI chr 2:8,027,496...8,032,573 JBrowse link
G Pnpla3 patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase involved_in ISO (PMID:15364929), (PMID:22560221)
(PMID:22560221)
BHF-UCL PMID:15364929 PMID:22560221 NCBI chr 1:253,556,033...253,575,213 JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) ARUK-UCL PMID:15576844 NCBI chr 2:170,923,673...170,927,490 JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:18635818), (PMID:3973011) BHF-UCL PMID:3973011 PMID:18635818 NCBI chr 8:40,753,291...40,756,012 JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chr14:43,986,187...44,037,832 JBrowse link
G Pak4 p21 (RAC1) activated kinase 4 involved_in ISO (PMID:38216738) MGI PMID:38216738 NCBI chr 2:167,404,476...167,442,990 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chr 7:45,548,144...45,581,376 JBrowse link
G Plin1 perilipin 1 involved_in ISO (PMID:15136565) MGI PMID:15136565 NCBI chr 2:120,513,622...120,524,852 JBrowse link
G Plin5 perilipin 5 involved_in ISO (PMID:22675471), (PMID:23345411) UniProt PMID:22675471 PMID:23345411 NCBI chr 4:87,501,087...87,506,708 JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:27322061) UniProt PMID:27322061 NCBI chr 8:36,555,463...36,715,316 JBrowse link
positive regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase involved_in ISO (PMID:19654421) UniProt PMID:19654421 NCBI chr 3:95,057,219...95,068,268 JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in ISO (PMID:16679289) UniProt PMID:16679289 NCBI chr 8:113,494,249...113,526,763 JBrowse link
G Apoa4 apolipoprotein A4 involved_in ISO (PMID:2307668) BHF-UCL PMID:2307668 NCBI chr 8:40,760,793...40,763,289 JBrowse link
G Apoa5 apolipoprotein A5 involved_in ISO (PMID:18635818) BHF-UCL PMID:18635818 NCBI chr 8:40,782,715...40,784,990 JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:10727238) BHF-UCL PMID:10727238 NCBI chr 2:170,940,090...170,945,166 JBrowse link
G Apoh apolipoprotein H ISO RGD PMID:7078428 RGD:8554677 NCBI chr 9:70,728,623...70,741,993 JBrowse link
G Daglb diacylglycerol lipase beta involved_in ISO (PMID:31991095) UniProt PMID:31991095 NCBI chr16:9,646,453...9,688,453 JBrowse link
G Fgf21 fibroblast growth factor 21 ISO RGD PMID:23262585 RGD:10401916 NCBI chr 2:153,906,528...153,908,115 JBrowse link
G Ldlr low density lipoprotein receptor ISO RGD PMID:28469073 RGD:12910100 NCBI chr 8:17,993,107...18,017,686 JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:16595669)
(PMID:10634941)
MGI PMID:10634941 PMID:16595669 NCBI chr17:16,287,765...16,311,232 JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23296834) AgBase PMID:23296834 NCBI chr18:23,369,139...23,390,562 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12423
    cellular process 11811
      metabolic process 7808
        catabolic process 1980
          lipid catabolic process 235
            glycerolipid catabolic process 57
              acylglycerol catabolic process 39
                triglyceride catabolic process 30
                  negative regulation of triglyceride catabolic process 8
                  positive regulation of triglyceride catabolic process 11
                  regulation of triglyceride catabolic process + 19
Path 2
Term Annotations click to browse term
  biological_process 12423
    cellular process 11811
      metabolic process 7808
        primary metabolic process 6806
          lipid metabolic process 996
            neutral lipid metabolic process 133
              acylglycerol metabolic process 132
                triglyceride metabolic process 107
                  triglyceride catabolic process 30
                    negative regulation of triglyceride catabolic process 8
                    positive regulation of triglyceride catabolic process 11
                    regulation of triglyceride catabolic process + 19
paths to the root