symbiont-mediated transformation of host cell - Ontology Report

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Term:	symbiont-mediated transformation of host cell	go back to main search page
Accession:	GO:0019087	browse the term
Definition:	A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses.
Synonyms:	exact_synonym:	host cell immortalization; host cell transformation; immortalization of host cell; transformation of host cell; transformation of host cell by virus; viral immortalization; viral transformation; viral transformation of host cell
	related_synonym:	immortalization of host cell by virus; virus-mediated transformation of host cell
	alt_id:	GO:0019088; GO:0020021
	xref:	Wikipedia:Viral_transformation

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Rat (3) Mouse (3) Human (3) Chinchilla (3) Bonobo (3) Dog (3) Squirrel (3) Pig (3) Green Monkey (3) Naked Mole-rat (3) All
Genes (3)

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

NCBI chr 5:19,485,033...19,491,418
Ensembl chr 5:19,485,096...19,491,417

matrix metallopeptidase 9

NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788

MYC proto-oncogene, bHLH transcription factor

NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078

Term paths to the root

Path 1
Term	Annotations
biological_process	18943
biological process involved in interspecies interaction between organisms	1840
modulation of process of another organism	122
symbiont-mediated perturbation of host process	3
symbiont-mediated perturbation of host cellular process	3
symbiont-mediated transformation of host cell	3
negative regulation of transformation of host cell by virus	0
positive regulation of transformation of host cell by virus	0
regulation of transformation of host cell by virus +	0
Path 2
Term	Annotations
biological_process	18943
biological process involved in interspecies interaction between organisms	1840
biological process involved in symbiotic interaction	165
biological process involved in interaction with host	129
symbiont-mediated perturbation of host process	3
symbiont-mediated perturbation of host cellular process	3
symbiont-mediated transformation of host cell	3
negative regulation of transformation of host cell by virus	0
positive regulation of transformation of host cell by virus	0
regulation of transformation of host cell by virus +	0

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