symbiont-mediated transformation of host cell - Ontology Report

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Term:	symbiont-mediated transformation of host cell	go back to main search page
Accession:	GO:0019087	browse the term
Definition:	A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses.
Synonyms:	exact_synonym:	host cell immortalization; host cell transformation; immortalization of host cell; transformation of host cell; transformation of host cell by virus; viral immortalization; viral transformation; viral transformation of host cell
	related_synonym:	immortalization of host cell by virus; virus-mediated transformation of host cell
	alt_id:	GO:0019088; GO:0020021
	xref:	Wikipedia:Viral_transformation

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Rat (3) Mouse (3) Human (3) Chinchilla (3) Bonobo (3) Dog (3) Squirrel (3) Pig (3) Green Monkey (3) Naked Mole-rat (3) All
Genes (3)

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

NCBI chr12:34,456,900...34,463,317
Ensembl chr12:35,184,943...35,188,443

matrix metallopeptidase 9

NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129

MYC proto-oncogene, bHLH transcription factor

NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863

Term paths to the root

Path 1
Term	Annotations
biological_process	19315
biological process involved in interspecies interaction between organisms	1756
modulation of process of another organism	121
symbiont-mediated perturbation of host process	3
symbiont-mediated perturbation of host cellular process	3
symbiont-mediated transformation of host cell	3
negative regulation of transformation of host cell by virus	0
positive regulation of transformation of host cell by virus	0
regulation of transformation of host cell by virus +	0
Path 2
Term	Annotations
biological_process	19315
biological process involved in interspecies interaction between organisms	1756
biological process involved in symbiotic interaction	169
biological process involved in interaction with host	128
symbiont-mediated perturbation of host process	3
symbiont-mediated perturbation of host cellular process	3
symbiont-mediated transformation of host cell	3
negative regulation of transformation of host cell by virus	0
positive regulation of transformation of host cell by virus	0
regulation of transformation of host cell by virus +	0

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