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ONTOLOGY REPORT - ANNOTATIONS

Term:viral gene expression
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Accession:GO:0019080 term browser browse the term
Definition:A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.
Synonyms:exact_synonym: viral genome expression


show annotations for term's descendants           Sort by:
DNA-templated viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:11096080) RGD PMID:11096080 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
early viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnt2 cyclin T2 involved_in ISO (PMID:21509660) RGD PMID:21509660 NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019 		JBrowse link
G Mon1b MON1 homolog B, secretory trafficking associated involved_in ISO (PMID:21509660) RGD PMID:21509660 NCBI chr19:41,617,372...41,625,347
Ensembl chr19:41,617,364...41,625,347 		JBrowse link
IRES-dependent viral translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csde1 cold shock domain containing E1 involved_in ISO
IEA		 (PMID:17947529)
GO_REF:0000107		 RGD
Ensembl		 PMID:17947529 GO_REF:0000107 NCBI chr 2:190,546,015...190,582,787
Ensembl chr 2:190,554,980...190,582,784 		JBrowse link
G Denr density regulated reinitiation and release factor involved_in ISO (PMID:20713520) RGD PMID:20713520 NCBI chr12:32,662,512...32,685,283
Ensembl chr12:32,662,516...32,683,843 		JBrowse link
G Eif2d eukaryotic translation initiation factor 2D involved_in ISO (PMID:20713520) RGD PMID:20713520 NCBI chr13:42,615,901...42,637,107
Ensembl chr13:42,615,911...42,639,719 		JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A involved_in ISO (PMID:23766293), (PMID:24357634), (PMID:9573242) RGD PMID:9573242 PMID:23766293 PMID:24357634 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B involved_in ISO (PMID:9573242) RGD PMID:9573242 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3d eukaryotic translation initiation factor 3, subunit D involved_in ISO (PMID:9573242) RGD PMID:9573242 NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206 		JBrowse link
G Eif3f eukaryotic translation initiation factor 3, subunit F involved_in ISO (PMID:9573242) RGD PMID:9573242 NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204 		JBrowse link
G Mcts1 MCTS1, re-initiation and release factor involved_in ISO
IEA		 (PMID:20713520)
GO_REF:0000107		 RGD
Ensembl		 PMID:20713520 GO_REF:0000107 NCBI chr  X:117,350,723...117,362,504
Ensembl chr  X:117,350,889...117,362,504 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:12414943) RGD PMID:12414943 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 involved_in ISO (PMID:17947529), (PMID:21518806) RGD PMID:17947529 PMID:21518806 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397 		JBrowse link
G Ssb small RNA binding exonuclease protection factor La involved_in ISO (PMID:12384597) RGD PMID:12384597 NCBI chr 3:54,616,616...54,626,203
Ensembl chr 3:54,616,619...54,626,203 		JBrowse link
late viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnt2 cyclin T2 involved_in ISO (PMID:21509660) RGD PMID:21509660 NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019 		JBrowse link
G Mon1b MON1 homolog B, secretory trafficking associated involved_in ISO (PMID:21509660) RGD PMID:21509660 NCBI chr19:41,617,372...41,625,347
Ensembl chr19:41,617,364...41,625,347 		JBrowse link
G Usf1 upstream transcription factor 1 involved_in ISO (PMID:2249772) RGD PMID:2249772 NCBI chr13:83,845,230...83,854,875
Ensembl chr13:83,822,035...83,854,885 		JBrowse link
modulation by host of viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psmc3 proteasome 26S subunit, ATPase 3 involved_in ISO
IEA		 (PMID:2194290), (PMID:8419915)
GO_REF:0000107		 RGD
Ensembl		 PMID:2194290 PMID:8419915 GO_REF:0000107 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358 		JBrowse link
negative regulation by host of viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 involved_in ISO (PMID:17690245) RGD PMID:17690245 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS		 (PMID:17005673)
GO_REF:0000024		 RGD
UniProt		 PMID:17005673 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:25086213) RGD PMID:25086213 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Pou2f3 POU class 2 homeobox 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:43,495,408...43,577,795
Ensembl chr 8:43,495,527...43,577,795 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000107		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G Tardbp TAR DNA binding protein involved_in ISO (PMID:7745706) RGD PMID:7745706 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055 		JBrowse link
G Tfap4 transcription factor AP-4 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386 		JBrowse link
G Zfp639 zinc finger protein 639 involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000107		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:115,292,431...115,305,798
Ensembl chr 2:115,292,516...115,303,628 		JBrowse link
negative regulation of viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:18249148) RGD PMID:18249148 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 involved_in ISO (PMID:20943977) RGD PMID:20943977 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203 		JBrowse link
G Larp7 La ribonucleoprotein 7, transcriptional regulator involved_in ISO (PMID:18249148), (PMID:18483487) RGD PMID:18249148 PMID:18483487 NCBI chr 2:215,997,641...216,012,833
Ensembl chr 2:215,997,649...216,012,865 		JBrowse link
G Mid2 midline 2 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr  X:104,354,692...104,456,757
Ensembl chr  X:104,355,316...104,453,473 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:16873258) RGD PMID:16873258 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Trim11 tripartite motif-containing 11 involved_in ISO
IBA		 (PMID:18248090)
GO_REF:0000033		 RGD
GO_Central		 PMID:18248090 GO_REF:0000033 NCBI chr10:43,758,299...43,771,138
Ensembl chr10:43,758,354...43,771,138 		JBrowse link
G Trim13 tripartite motif-containing 13 involved_in ISO
IEA		 (PMID:18248090)
GO_REF:0000107		 RGD
Ensembl		 PMID:18248090 GO_REF:0000107 NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677 		JBrowse link
G Trim14 tripartite motif-containing 14 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr 5:60,800,568...60,824,858
Ensembl chr 5:60,800,032...60,824,858 		JBrowse link
G Trim21 tripartite motif-containing 21 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440 		JBrowse link
G Trim27 tripartite motif-containing 27 involved_in ISO
IBA		 (PMID:18248090)
GO_REF:0000033		 RGD
GO_Central		 PMID:18248090 GO_REF:0000033 NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643 		JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
G Trim62 tripartite motif-containing 62 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915 		JBrowse link
G Trim8 tripartite motif-containing 8 involved_in ISO (PMID:18248090) RGD PMID:18248090 NCBI chr 1:245,369,632...245,384,513
Ensembl chr 1:245,369,632...245,384,513 		JBrowse link
G Ubp1 upstream binding protein 1 involved_in ISO (PMID:8114710) RGD PMID:8114710 NCBI chr 8:113,869,771...113,915,625
Ensembl chr 8:113,869,979...113,915,625 		JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
ISO		 GO_REF:0000024
(PMID:14679154)		 UniProt
RGD		 PMID:14679154 GO_REF:0000024 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
positive regulation by host of viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnt1 cyclin T1 involved_in ISO (PMID:10866664) RGD PMID:10866664 NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 involved_in ISO
IEA		 (PMID:10866664)
GO_REF:0000107		 RGD
Ensembl		 PMID:10866664 GO_REF:0000107 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410 		JBrowse link
G Chd1 chromodomain helicase DNA binding protein 1 involved_in ISO (PMID:25297984) RGD PMID:25297984 NCBI chr 1:56,661,743...56,729,119
Ensembl chr 1:56,664,054...56,728,125 		JBrowse link
G Ctdp1 CTD phosphatase subunit 1 involved_in ISO (PMID:15723517) RGD PMID:15723517 NCBI chr18:73,854,277...73,916,232
Ensembl chr18:73,854,282...73,916,457 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:16687403) RGD PMID:16687403 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Hpn hepsin involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000107		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Rrp1b ribosomal RNA processing 1B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:10,123,111...10,148,704
Ensembl chr20:10,123,125...10,147,928 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 involved_in ISO
IEA		 (PMID:16687403)
GO_REF:0000107		 RGD
Ensembl		 PMID:16687403 GO_REF:0000107 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Smarcb1 SWI/SNF related BAF chromatin remodeling complex subunit B1 involved_in ISO (PMID:16687403) RGD PMID:16687403 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620 		JBrowse link
G Snw1 SNW domain containing 1 involved_in ISO (PMID:15905409), (PMID:19818711) RGD PMID:15905409 PMID:19818711 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Sp1 Sp1 transcription factor involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Taf11 TATA-box binding protein associated factor 11 involved_in ISO (PMID:9108034) RGD PMID:9108034 NCBI chr20:5,955,774...5,963,593
Ensembl chr20:5,955,777...5,961,905 		JBrowse link
G Tfap4 transcription factor AP-4 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386 		JBrowse link
G Zfp639 zinc finger protein 639 involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000107		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:115,292,431...115,305,798
Ensembl chr 2:115,292,516...115,303,628 		JBrowse link
positive regulation of viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:11096080) RGD PMID:11096080 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA from cytomegalovirus immediate-early promoter RGD PMID:11746500 RGD:2293493 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Mdfic MyoD family inhibitor domain containing involved_in ISO (PMID:10671520) RGD PMID:10671520 NCBI chr 4:43,972,310...44,052,162
Ensembl chr 4:43,972,507...44,052,161 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:21191019) RGD PMID:21191019 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Pfn1 profilin 1 IMP RGD PMID:12740026 RGD:2324854 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Rsf1 remodeling and spacing factor 1 involved_in ISO (PMID:11788598) RGD PMID:11788598 NCBI chr 1:151,892,055...152,015,089
Ensembl chr 1:151,892,434...152,009,051 		JBrowse link
positive regulation of viral translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg12 autophagy related 12 involved_in ISO (PMID:19666601) RGD PMID:19666601 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 involved_in ISO
IEA		 (PMID:19666601)
GO_REF:0000107		 RGD
Ensembl		 PMID:19666601 GO_REF:0000107 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
regulation of viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tarbp2 Tarbp2 subunit of RISC loading complex involved_in ISO
IEA
ISS		 (PMID:11641396)
GO_REF:0000002
GO_REF:0000024		 RGD
InterPro
UniProt		 PMID:11641396 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314 		JBrowse link
viral protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spcs1 signal peptidase complex subunit 1 involved_in ISO (PMID:27383988) RGD PMID:27383988 NCBI chr16:6,190,208...6,191,776
Ensembl chr16:6,190,262...6,192,000 		JBrowse link
G Spcs3 signal peptidase complex subunit 3 involved_in ISO (PMID:27383988) RGD PMID:27383988 NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746 		JBrowse link
viral transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2b general transcription factor IIB involved_in ISO
ISS
IEA		 (PMID:14644612), (PMID:24441171)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:14644612 PMID:24441171 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651 		JBrowse link
viral translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16601681)		 UniProt
RGD		 PMID:16601681 GO_REF:0000024 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 acts_upstream_of_positive_effect ISO (PMID:33876849) RGD PMID:33876849 NCBI chr 2:51,523,190...51,550,241
Ensembl chr 2:51,522,921...51,550,241 		JBrowse link
viral translational frameshifting term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oaz1 ornithine decarboxylase antizyme 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310 		JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:66,199,694...66,213,513
Ensembl chr 8:66,199,706...66,231,453 		JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399 		JBrowse link
G Shfl shiftless antiviral inhibitor of ribosomal frameshifting involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:30682371)		 UniProt
Ensembl
RGD		 PMID:30682371 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:19,408,298...19,414,084
Ensembl chr 8:19,408,333...19,413,971 		JBrowse link
viral translational termination-reinitiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif3a eukaryotic translation initiation factor 3, subunit A involved_in ISO (PMID:21347434) RGD PMID:21347434 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B involved_in ISO (PMID:21347434) RGD PMID:21347434 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3d eukaryotic translation initiation factor 3, subunit D involved_in ISO (PMID:21347434) RGD PMID:21347434 NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206 		JBrowse link
G Eif3g eukaryotic translation initiation factor 3, subunit G involved_in ISO
IEA		 (PMID:21347434)
GO_REF:0000107		 RGD
Ensembl		 PMID:21347434 GO_REF:0000107 NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808 		JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L involved_in ISO (PMID:21347434) RGD PMID:21347434 NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    viral process 322
      viral gene expression 74
        viral mRNA export from host cell nucleus 0
        viral protein processing 2
        viral transcription + 51
        viral translation + 21
paths to the root