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ONTOLOGY REPORT - ANNOTATIONS

Term:phenol-containing compound metabolic process
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Accession:GO:0018958 term browser browse the term
Definition:The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
Comment:Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds.
Synonyms:exact_synonym: carbolic acid metabolic process;   carbolic acid metabolism;   hydroxybenzene metabolic process;   hydroxybenzene metabolism;   phenol-containing compound metabolism
 xref: UM-BBD_pathwayID:phe


show annotations for term's descendants           Sort by:
phenol-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP bisphenol A RGD PMID:18191889 RGD:4831838 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP bisphenol A RGD PMID:18191889 RGD:4831838 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2182307 (PMID:17052995)		 Ensembl
RGD		 PMID:17052995 GO_REF:0000107 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP gossypol RGD PMID:19429456 RGD:4890959 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP gossypol RGD PMID:19429456 RGD:4890959 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Star steroidogenic acute regulatory protein IEP bisphenol A RGD PMID:18191889 RGD:4831838 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 involved_in ISO (PMID:9463486) RGD PMID:9463486 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483 		JBrowse link
4-nitrophenol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 involved_in ISO
IEA		 (PMID:9348445)
GO_REF:0000107		 RGD
Ensembl		 PMID:9348445 GO_REF:0000107 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 IDA RGD PMID:11181495 RGD:2301074 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:17194738 RGD:5131263 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Ddc dopa decarboxylase involved_in TAS
IEA		 GO_REF:0000043 UniProt
RGD		 PMID:12047348 GO_REF:0000043, RGD:727571 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Hdc histidine decarboxylase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Th tyrosine hydroxylase IDA RGD PMID:20025246 RGD:4139888 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
catecholamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase involved_in ISO
IEA
IBA
ISS		 (PMID:11559542), (PMID:15645182), (PMID:21846718)
GO_REF:0000104
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
UniProt
GO_Central
Ensembl		 PMID:11559542 PMID:15645182 PMID:21846718 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:18794526)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:18794526 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
G Maoa monoamine oxidase A NAS RGD PMID:12388421 RGD:629546 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of
acts_upstream_of_or_within		 ISO MGI:1856098 (PMID:17511) RGD PMID:17511 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO MGI:2178542 (PMID:11849292) RGD PMID:11849292 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Dbh dopamine beta-hydroxylase IC RGD PMID:11521740 RGD:1625401 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddc dopa decarboxylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Maoa monoamine oxidase A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Mtpn myotrophin IEP RGD PMID:12051753 RGD:625450 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 IDA RGD PMID:6959650 RGD:2301075 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1d1 sulfotransferase family 1D, member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:20,441,135...20,476,341
Ensembl chr14:20,441,924...20,476,341 		JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:20097214 RGD:6903884 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:20097214 RGD:6903884 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IEP RGD PMID:12438507 RGD:704388 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:19818757 RGD:5143981 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Dao D-amino-acid oxidase involved_in ISO
ISS		 (PMID:17303072)
(PMID:17042912)
GO_REF:0000024		 RGD
UniProt		 PMID:17042912 PMID:17303072 GO_REF:0000024 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741 		JBrowse link
G Ddc dopa decarboxylase involved_in IDA
ISO
IEA		 (PMID:19703902)
GO_REF:0000107
GO_REF:0000041		 RGD
Ensembl
UniProt		 PMID:19703902 PMID:12703659 GO_REF:0000041 GO_REF:0000107, RGD:4139893 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:16338639) RGD PMID:16338639 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO MGI:3027995 (PMID:15218106) RGD PMID:15218106 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2429971 (PMID:16782508), (PMID:9608532)		 Ensembl
RGD		 PMID:9608532 PMID:16782508 GO_REF:0000107 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (PMID:9520487) RGD PMID:9520487 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:1888382 (PMID:10707987) RGD PMID:10707987 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16257223)		 UniProt
RGD		 PMID:16257223 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Th tyrosine hydroxylase involved_in IEA
ISO		 GO_REF:0000041
(PMID:12457228), (PMID:19703902)		 UniProt
RGD		 PMID:12457228 PMID:19703902 GO_REF:0000041 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA
IMP		 MGI:1860450 (PMID:7592982), (PMID:7715703), (PMID:9520487)
GO_REF:0000033
PMID:11943812		 RGD
GO_Central		 PMID:7592982 PMID:7715703 PMID:9520487 PMID:2427363 PMID:11943812 More... GO_REF:0000033, RGD:1580046, RGD:5129111, RGD:5130972 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO (PMID:9520487) RGD PMID:9520487 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA
ISS		 (PMID:3443096), (PMID:7961964)
(PMID:27148966), (PMID:7715704)
MGI:1857556 (PMID:10051631)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:3443096 PMID:7715704 PMID:7961964 PMID:10051631 PMID:27148966 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Maoa monoamine oxidase A acts_upstream_of_or_within ISO (PMID:9520487) RGD PMID:9520487 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Pde1b phosphodiesterase 1B acts_upstream_of_positive_effect ISO MGI:3604470 (PMID:17559891) RGD PMID:17559891 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (PMID:9520487) RGD PMID:9520487 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098|MGI:1856466 (PMID:1752214), (PMID:8174230) RGD PMID:1752214 PMID:8174230 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000104
MGI:2178542 (PMID:11849292), (PMID:17881525), (PMID:19770404), (PMID:22169008), (PMID:23863468), (PMID:24591155), (PMID:27388330)		 GO_Central
UniProt
RGD		 PMID:11849292 PMID:17881525 PMID:19770404 PMID:22169008 PMID:23863468 More... GO_REF:0000033 GO_REF:0000104 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:10945868 RGD:1599723 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Ddc dopa decarboxylase TAS RGD PMID:7567987 RGD:727686 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO (PMID:7925842) RGD PMID:7925842 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Gnat2 G protein subunit alpha transducin 2 acts_upstream_of_or_within ISO MGI:3588845 (PMID:32049342) RGD PMID:32049342 NCBI chr 2:195,726,371...195,735,866
Ensembl chr 2:195,726,762...195,735,866 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1928285 (PMID:11160454)		 Ensembl
RGD		 PMID:11160454 GO_REF:0000107 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857299 (PMID:1432691), (PMID:7509865), (PMID:9886073)		 Ensembl
RGD		 PMID:1432691 PMID:7509865 PMID:9886073 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
G Myo5a myosin VA IMP RGD PMID:29217155 RGD:42721980 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 acts_upstream_of_or_within ISO MGI:3527173 (PMID:28327638) RGD PMID:28327638 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846 		JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:15544851 RGD:1580153 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 acts_upstream_of_or_within ISO MGI:2429971 (PMID:12385813) RGD PMID:12385813 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within
NOT|acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2678247 (PMID:12915482)
MGI:3055212 (PMID:15684050)		 Ensembl
RGD		 PMID:12915482 PMID:15684050 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (PMID:21178975) RGD PMID:21178975 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (PMID:28507136) RGD PMID:28507136 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:1889011 (PMID:15465911) RGD PMID:15465911 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sncaip synuclein, alpha interacting protein involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:14506261)		 ParkinsonsUK-UCL
RGD		 PMID:14506261 GO_REF:0000024 NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929 		JBrowse link
G Sncb synuclein, beta acts_upstream_of_or_within ISO MGI:1277151 (PMID:15465911) RGD PMID:15465911 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (PMID:16532389) RGD PMID:16532389 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnmt phenylethanolamine-N-methyltransferase involved_in TAS
IEA
IDA
IC		 GO_REF:0000041 UniProt
RGD		 PMID:11514309 PMID:7914070 PMID:7503429 GO_REF:0000041, RGD:628457, RGD:4139902, RGD:4139901 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
epinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098|MGI:1856466 (PMID:1752214) RGD PMID:1752214 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (PMID:21178975) RGD PMID:21178975 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpd1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within
involved_in		 ISO MGI:3692960 (PMID:11147825)
MGI:3692960 (PMID:25603051)		 RGD PMID:11147825 PMID:25603051 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529 		JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 involved_in ISO MGI:2181289 (PMID:9974390) RGD PMID:9974390 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901 		JBrowse link
homogentisate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505 		JBrowse link
melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asip agouti signaling protein involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:8449404)
MGI:1855937 (PMID:7665913)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:7665913 PMID:8449404 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171 		JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11434569)		 UniProt
RGD		 PMID:11434569 GO_REF:0000024 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162 		JBrowse link
G Dct dopachrome tautomerase acts_upstream_of_or_within ISO MGI:1856379 (PMID:7665913) RGD PMID:7665913 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Ddt D-dopachrome tautomerase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482 		JBrowse link
G Mc1r melanocortin 1 receptor acts_upstream_of_or_within ISO MGI:1856028 (PMID:7665913) RGD PMID:7665913 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO MGI:1856004 (PMID:7665913) RGD PMID:7665913 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1856114 (PMID:7665913), (PMID:9548375)		 GO_Central
RGD		 PMID:7665913 PMID:9548375 GO_REF:0000033 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Pmel premelanosome protein acts_upstream_of_or_within ISO MGI:1857040 (PMID:7665913) RGD PMID:7665913 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of ISO (PMID:18166528) RGD PMID:18166528 NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:8126111)		 Ensembl
RGD		 PMID:8126111 GO_REF:0000107 NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276 		JBrowse link
G Tyr tyrosinase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:8126111)
MGI:1855976|MGI:1855978 (PMID:7665913), (PMID:9548375)
GO_REF:0000033		 RGD
GO_Central		 PMID:7665913 PMID:8126111 PMID:9548375 GO_REF:0000033 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase involved_in ISO (PMID:2169885), (PMID:33100333) RGD PMID:2169885 PMID:33100333 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) RGD PMID:25513726 PMID:32966160 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in ISO (PMID:32966160)
(PMID:35469906)		 RGD PMID:32966160 PMID:35469906 NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317 		JBrowse link
melanin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2156165 (PMID:11709185)		 Ensembl
RGD		 PMID:11709185 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO MGI:1856004 (PMID:9548375) RGD PMID:9548375 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 acts_upstream_of_or_within ISO MGI:1855960 (PMID:9548375) RGD PMID:9548375 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645 (PMID:22627278) RGD PMID:22627278 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
negative regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (PMID:17511) RGD PMID:17511 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Nt5dc2 5'-nucleotidase domain containing 2 involved_in IMP PMID:31279527 UniProt PMID:31279527 RGD:408345212 NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537 		JBrowse link
negative regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nt5dc2 5'-nucleotidase domain containing 2 involved_in IMP PMID:31279527 UniProt PMID:31279527 RGD:408345212 NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537 		JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15190105 RGD:2289786 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:17018023 RGD:1625003 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:18981141) RGD PMID:18981141 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Snca synuclein alpha involved_in IMP PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (PMID:29025994) RGD PMID:29025994 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988 		JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:31097585) RGD PMID:31097585 NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16272156)		 UniProt
RGD		 PMID:16272156 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO (PMID:18166528) RGD PMID:18166528 NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231 		JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:23569434)		 Ensembl
RGD		 PMID:23569434 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856097|MGI:1856098 (PMID:4405722), (PMID:4858102) RGD PMID:4405722 PMID:4858102 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 TAS
ISO
IBA
ISS
IEA
IMP		 (PMID:27148966), (PMID:7715704)
MGI:1857556 (PMID:10051631), (PMID:9603211)
GO_REF:0000033
GO_REF:0000024
GO_REF:0000041		 RGD
GO_Central
UniProt		 PMID:7715704 PMID:9603211 PMID:10051631 PMID:27148966 PMID:11914591 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000041, RGD:727567, RGD:1625403 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2153826 (PMID:10835639) RGD PMID:10835639 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 GO_REF:0000107
(PMID:19008477)		 Ensembl
RGD		 PMID:19008477 GO_REF:0000107 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in ISO (PMID:18094025) RGD PMID:18094025 NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Kl Klotho IMP RGD PMID:20086041 RGD:10403068 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
norepinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 IDA RGD PMID:10424772 RGD:8548769 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102|MGI:1856466 (PMID:4147174) RGD PMID:4147174 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO MGI:2178542 (PMID:11849292), (PMID:24591155) RGD PMID:11849292 PMID:24591155 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO		 GO_REF:0000107
MGI:2687362 (PMID:25197047)		 Ensembl
RGD		 PMID:25197047 GO_REF:0000107 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Epas1 endothelial PAS domain protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861921 (PMID:9808618)		 Ensembl
RGD		 PMID:9808618 GO_REF:0000107 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E acts_upstream_of_or_within ISO MGI:2429638 (PMID:11784869) RGD PMID:11784869 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IDA RGD PMID:3945626 RGD:5130757 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3050230 (PMID:15249681)		 Ensembl
RGD		 PMID:15249681 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:23926250)		 GO_Central
RGD		 PMID:23926250 GO_REF:0000033 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (PMID:21178975) RGD PMID:21178975 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G Rtl4 retrotransposon Gag like 4 acts_upstream_of_or_within ISO MGI:5789261 (PMID:26402067) RGD PMID:26402067 NCBI chr  X:108,231,052...108,641,768
Ensembl chr  X:108,633,651...108,640,050 		JBrowse link
G Slitrk1 SLIT and NTRK-like family, member 1 acts_upstream_of_or_within ISO (PMID:36085162) RGD PMID:36085162 NCBI chr15:85,723,252...85,727,290
Ensembl chr15:85,724,475...85,727,509 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (PMID:16532389) RGD PMID:16532389 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IMP RGD PMID:11521740 RGD:1625401 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(PMID:19703902)		 ParkinsonsUK-UCL
RGD		 PMID:19703902 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26203154) RGD PMID:26203154 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11239920 RGD:10047061 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO MGI:3027995 (PMID:15218106) RGD PMID:15218106 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IEA		 (PMID:8643611)
GO_REF:0000107		 RGD
Ensembl		 PMID:8643611 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Npy neuropeptide Y IDA RGD PMID:19579268 RGD:10448966 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:21291857) RGD PMID:21291857 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Asip agouti signaling protein involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P07147|UniProtKB:Q60696 (PMID:21949658)		 Ensembl
RGD		 PMID:21949658 GO_REF:0000107 NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171 		JBrowse link
G Atp7a ATPase copper transporting alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:11092760)		 UniProt
RGD		 PMID:11092760 GO_REF:0000024 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:23334344) RGD PMID:23334344 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21291857)		 UniProt
Ensembl
RGD		 PMID:21291857 GO_REF:0000024 GO_REF:0000107 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:28842328) RGD PMID:28842328 NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847 		JBrowse link
G Pmel premelanosome protein involved_in ISO (PMID:21949658) RGD PMID:21949658 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746 		JBrowse link
G Rab38 RAB38, member RAS oncogene family IMP RGD PMID:17043139 RGD:152025192 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in ISO (PMID:21996312)
UniProtKB:Q03288|UniProtKB:Q60696 (PMID:21949658)		 RGD PMID:21949658 PMID:21996312 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
positive regulation of thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19248180), (PMID:19723756) RGD PMID:19248180 PMID:19723756 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Hpn hepsin involved_in ISS
ISO		 GO_REF:0000024
(PMID:17620368)		 UniProt
RGD		 PMID:17620368 GO_REF:0000024 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Pax8 paired box 8 involved_in ISO
ISS		 (PMID:15356023)
GO_REF:0000024
(PMID:12586753)		 RGD
UniProt		 PMID:12586753 PMID:15356023 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 involved_in ISO
IEA		 (PMID:18566113)
GO_REF:0000107		 RGD
Ensembl		 PMID:18566113 GO_REF:0000107 NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289 		JBrowse link
regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vhl von Hippel-Lindau tumor suppressor IMP RGD PMID:11912140 RGD:619592 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member involved_in ISS
ISO		 GO_REF:0000024
(PMID:26711020)		 UniProt
RGD		 PMID:26711020 GO_REF:0000024 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (PMID:11282258) RGD PMID:11282258 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857158 (PMID:11438590)		 Ensembl
RGD		 PMID:11438590 GO_REF:0000107 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd4 dopamine receptor D4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178631 (PMID:9323127)		 Ensembl
RGD		 PMID:9323127 GO_REF:0000107 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in ISS
ISO		 GO_REF:0000024
(PMID:11080193)		 UniProt
RGD		 PMID:11080193 GO_REF:0000024 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12915123)		 Ensembl
RGD		 PMID:12915123 GO_REF:0000107 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing acts_upstream_of_or_within ISO MGI:5006973 (PMID:22214848) RGD PMID:22214848 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:22314364)
GO_REF:0000107		 RGD
Ensembl		 PMID:22314364 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (PMID:9247269), (PMID:9520487) RGD PMID:9247269 PMID:9520487 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:8574643 RGD:2305963 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter involved_in ISO (PMID:22649030) RGD PMID:22649030 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO
IBA		 (PMID:33208952)
GO_REF:0000033
(PMID:31117290)		 RGD
GO_Central		 PMID:31117290 PMID:33208952 GO_REF:0000033 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (PMID:16037214) RGD PMID:16037214 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
regulation of serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member involved_in ISS
ISO		 GO_REF:0000024
(PMID:26711020)		 UniProt
RGD		 PMID:26711020 GO_REF:0000024 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
regulation of thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duoxa1 dual oxidase maturation factor 1 acts_upstream_of_or_within ISO MGI:1914061 (PMID:22301785) RGD PMID:22301785 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 acts_upstream_of_or_within ISO MGI:2384861 (PMID:22301785) RGD PMID:22301785 NCBI chr 3:109,245,337...109,249,055
Ensembl chr 3:109,245,476...109,248,968 		JBrowse link
serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:10027744 GO_REF:0000033, RGD:5129182 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Tph1 tryptophan hydroxylase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:14697203)		 UniProt
RGD		 PMID:14697203 GO_REF:0000024 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Tph2 tryptophan hydroxylase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:23098818 RGD:11353778 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Tph1 tryptophan hydroxylase 1 TAS RGD PMID:12153488 RGD:625621 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
serotonin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857092 (PMID:2765934) RGD PMID:2765934 NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (PMID:8174230) RGD PMID:8174230 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Btbd9 BTB domain containing 9 acts_upstream_of_or_within ISO MGI:4127237 (PMID:22678064) RGD PMID:22678064 NCBI chr20:8,286,337...8,645,567
Ensembl chr20:8,288,711...8,643,960 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1928285 (PMID:11160454)		 Ensembl
RGD		 PMID:11160454 GO_REF:0000107 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in ISS
ISO		 GO_REF:0000024
(PMID:11080193)		 UniProt
RGD		 PMID:11080193 GO_REF:0000024 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Maoa monoamine oxidase A IDA
IMP		 Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741 PMID:11263670 PMID:11754741 RGD:1600709, RGD:1600713, RGD:1600709 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Pde1b phosphodiesterase 1B acts_upstream_of_or_within ISO MGI:3604470 (PMID:17559891) RGD PMID:17559891 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:23926250)		 GO_Central
RGD		 PMID:23926250 GO_REF:0000033 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (PMID:16532389) RGD PMID:16532389 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:15936112 RGD:4891926 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
thyroid hormone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio2 iodothyronine deiodinase 2 acts_upstream_of_or_within ISO MGI:2182450 (PMID:11731615) RGD PMID:11731615 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:20203194)
MGI:2664293 (PMID:16410833), (PMID:20203194), (PMID:25002520)		 RGD PMID:16410833 PMID:20203194 PMID:25002520 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cga glycoprotein hormones, alpha polypeptide involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857152 (PMID:12114718)		 GO_Central
RGD		 PMID:12114718 GO_REF:0000033 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Cpq carboxypeptidase Q involved_in IDA
IBA		 PMID:22127294
GO_REF:0000033		 GO_Central PMID:22127294 GO_REF:0000033, RGD:8554022 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546 		JBrowse link
G Ctsb cathepsin B involved_in IEA
ISO		 GO_REF:0000107
(PMID:12782676)		 Ensembl
RGD		 PMID:12782676 GO_REF:0000107 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsk cathepsin K involved_in ISO
ISS		 (PMID:11082042)
(PMID:12782676)
GO_REF:0000024		 RGD
UniProt		 PMID:11082042 PMID:12782676 GO_REF:0000024 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctsl cathepsin L involved_in ISO (PMID:12782676) RGD PMID:12782676 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Dio2 iodothyronine deiodinase 2 IDA RGD PMID:15550511 RGD:1626436 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Duox1 dual oxidase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 involved_in TAS
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:12538618 GO_REF:0000041, RGD:632568 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Foxe1 forkhead box E1 acts_upstream_of_or_within ISO MGI:2181780 (PMID:9697704) RGD PMID:9697704 NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:1861125 (PMID:10882104) RGD PMID:10882104 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Slc16a10 solute carrier family 16 member 10 acts_upstream_of_or_within_negative_effect ISO MGI:1203732 (PMID:24248460) RGD PMID:24248460 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 acts_upstream_of_or_within_negative_effect ISO MGI:1919722|MGI:3710233 (PMID:24248460) RGD PMID:24248460 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slc26a7 solute carrier family 26 member 7 involved_in ISO (PMID:30333321) RGD PMID:30333321 NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 involved_in TAS
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:8559252 GO_REF:0000002, RGD:68854 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Tg thyroglobulin involved_in TAS
ISO
IBA
IEA
IDA		 (PMID:12782676)
GO_REF:0000033
GO_REF:0000107
(PMID:11082042), (PMID:12387814)
(PMID:32025030)		 RGD
GO_Central
Ensembl		 PMID:11082042 PMID:12387814 PMID:12782676 PMID:32025030 PMID:11884402 More... GO_REF:0000033 GO_REF:0000107, RGD:728752, RGD:1600150 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tpo thyroid peroxidase involved_in TAS
ISO
IEA		 (PMID:12387814)
GO_REF:0000041		 RGD
UniProt		 PMID:12387814 PMID:15917231 GO_REF:0000041, RGD:1599649 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
thyroid hormone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crym crystallin, mu involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3703787 (PMID:17264173)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:17264173 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633 		JBrowse link
G Dio1 iodothyronine deiodinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio2 iodothyronine deiodinase 2 involved_in TAS
IBA
ISO
IDA		 GO_REF:0000033
(PMID:19651899)		 GO_Central
RGD		 PMID:19651899 PMID:11934678 PMID:15550511 GO_REF:0000033, RGD:628323, RGD:1626436 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 involved_in TAS
IBA
ISO		 GO_REF:0000033
UniProtKB:P36021 (PMID:26305885)		 GO_Central
RGD		 PMID:26305885 PMID:7622463 GO_REF:0000033, RGD:68236 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Duox2 dual oxidase 2 acts_upstream_of_or_within ISO MGI:3712359 (PMID:17440044) RGD PMID:17440044 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4 acts_upstream_of_or_within ISO MGI:3849682 (PMID:19349303) RGD PMID:19349303 NCBI chr 2:28,253,325...28,283,082
Ensembl chr 2:28,252,860...28,283,082 		JBrowse link
G Iyd iodotyrosine deiodinase involved_in ISO
IBA
ISS		 (PMID:25395621)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:25395621 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 acts_upstream_of_or_within ISO MGI:1856525 RGD MGI:85368 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Reln reelin acts_upstream_of_or_within ISO MGI:1856398 RGD MGI:85368 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 acts_upstream_of ISO UniProtKB:P55073 (PMID:26305885) RGD PMID:26305885 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 IDA RGD PMID:11316767 RGD:727314 NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 involved_in ISO
IDA		 (PMID:11368519)
(PMID:9644246)
PMID:8530477
(PMID:9443824), (PMID:9463486)		 RGD PMID:9443824 PMID:9463486 PMID:9644246 PMID:11368519 PMID:8530477 RGD:1299515 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 involved_in ISO (PMID:10199779) RGD PMID:10199779 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tg thyroglobulin acts_upstream_of_or_within ISO MGI:1856829 (PMID:3803305) RGD PMID:3803305 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Ttr transthyretin TAS RGD PMID:11995998 RGD:737655 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      metabolic process 11953
        organic hydroxy compound metabolic process 585
          phenol-containing compound metabolic process 137
            (+)-lariciresinol metabolic process + 0
            (+)-larreatricin metabolic process 0
            (+)-pinoresinol metabolic process + 0
            (+)-secoisolariciresinol metabolic process + 0
            (-)-lariciresinol metabolic process + 0
            (-)-pinoresinol metabolic process + 0
            (-)-secoisolariciresinol metabolic process + 0
            (R)-4-hydroxymandelate metabolic process + 0
            1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process + 0
            2-hydroxybenzoyl-CoA metabolic process + 0
            3-hydroxybenzyl alcohol metabolic process 0
            3-hydroxyphenylacetate metabolic process + 0
            4-hydroxyphenylacetate metabolic process + 0
            4-nitrophenol metabolic process + 2
            F-9775A metabolic process + 0
            F-9775B metabolic process + 0
            aerobic phenol-containing compound metabolic process + 0
            anaerobic phenol-containing compound metabolic process + 0
            asperthecin metabolic process + 0
            averantin metabolic process + 0
            bromoxynil metabolic process 0
            catechol-containing compound metabolic process + 67
            cresol metabolic process + 0
            curcumin metabolic process + 0
            diorcinol metabolic process + 0
            emericellin metabolic process + 0
            emodin metabolic process + 0
            endocrocin metabolic process + 0
            eugenol metabolic process + 0
            ferulate metabolic process + 0
            fonsecin metabolic process + 0
            funalenone metabolic process + 0
            glycerophosphate shuttle 2
            homogentisate metabolic process + 1
            melanin metabolic process + 26
            monodictyphenone metabolic process + 0
            neosartoricin metabolic process + 0
            novobiocin metabolic process + 0
            o-orsellinic acid metabolic process + 0
            octopamine metabolic process + 3
            orcinol metabolic process + 0
            pentachlorophenol metabolic process + 0
            phenol metabolic process + 0
            phenol-containing compound biosynthetic process + 54
            phenol-containing compound catabolic process + 11
            pyochelin metabolic process + 0
            resorcinol metabolic process 0
            salicylic acid metabolic process + 0
            serotonin metabolic process + 15
            shamixanthone metabolic process + 0
            sinapate ester metabolic process + 0
            sinapate metabolic process + 0
            thyroid hormone metabolic process + 35
            vanillin metabolic process + 0
paths to the root