ONTOLOGY REPORT - ANNOTATIONS
Term: dibenzo-p-dioxin metabolic process
Accession: GO:0018894
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Definition: The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.
Synonyms: exact_synonym: dibenzo-p-dioxin metabolism; oxanthrene metabolic process; oxanthrene metabolism; phenodioxin metabolic process; phenodioxin metabolism
xref: UM-BBD_pathwayID:dpd
G
Ccl5
C-C motif chemokine ligand 5
IEP
RGD
PMID:20059583
RGD:4889921
NCBI chr10:68,820,330...68,824,906
G
Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
IEP
2,3,7,8-tetrachlorodibenzo-p-dioxin
RGD
PMID:18637154
RGD:4778755
NCBI chr 8:58,422,807...58,434,342
G
Cyp11b1
cytochrome P450, family 11, subfamily b, polypeptide 1
IEP
RGD
PMID:16254025
RGD:4889135
NCBI chr 7:106,772,597...106,780,536
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
NOT|acts_upstream_of_or_within
IDA ISO
MGI:2182307 (PMID:16636061)
RGD
PMID:16636061 PMID:12464257
RGD:727674
NCBI chr 8:66,991,940...66,998,014
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1861917|MGI:2182351 (PMID:16636061), (PMID:9240455)
Ensembl RGD
PMID:9240455 PMID:16636061
GO_REF:0000107
NCBI chr 8:66,971,261...66,978,149
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
NOT|acts_upstream_of_or_within
ISO
MGI:2154690 (PMID:16636061)
RGD
PMID:16636061
NCBI chr 6:21,093,927...21,103,091
G
Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IEP
2,3,7,8-tetrachlorodibenzo-p-dioxin
RGD
PMID:18637154
RGD:4778755
NCBI chr 2:188,858,574...188,864,694
G
Prkcb
protein kinase C, beta
IEP
RGD
PMID:16797713
RGD:5131886
NCBI chr 1:186,263,397...186,594,743
G
Srd5a2
steroid 5 alpha-reductase 2
IEP
RGD
PMID:11222880
RGD:4892000
NCBI chr 6:27,178,089...27,217,588
G
Star
steroidogenic acute regulatory protein
IEP
2,3,7,8-tetrachlorodibenzo-p-dioxin
RGD
PMID:18637154
RGD:4778755
NCBI chr16:72,969,824...72,974,447
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
IDA IMP
2,3,7,8-tetrachlorodibenzo-p-dioxin
RGD
PMID:15812643 PMID:12914780
RGD:2306662 , RGD:2306673
NCBI chr 8:66,991,940...66,998,014
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all