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ONTOLOGY REPORT - ANNOTATIONS


Term:dibenzo-p-dioxin metabolic process
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Accession:GO:0018894 term browser browse the term
Definition:The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.
Synonyms:exact_synonym: dibenzo-p-dioxin metabolism;   oxanthrene metabolic process;   oxanthrene metabolism;   phenodioxin metabolic process;   phenodioxin metabolism
 xref: UM-BBD_pathwayID:dpd



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dibenzo-p-dioxin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 IEP RGD PMID:20059583 RGD:4889921 NCBI chr10:68,820,330...68,824,906 JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP 2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:18637154 RGD:4778755 NCBI chr 8:58,422,807...58,434,342 JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IEP RGD PMID:16254025 RGD:4889135 NCBI chr 7:106,772,597...106,780,536 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 NOT|acts_upstream_of_or_within IDA
ISO
MGI:2182307 (PMID:16636061) RGD PMID:16636061 PMID:12464257 RGD:727674 NCBI chr 8:66,991,940...66,998,014 JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1861917|MGI:2182351 (PMID:16636061), (PMID:9240455)
Ensembl
RGD
PMID:9240455 PMID:16636061 GO_REF:0000107 NCBI chr 8:66,971,261...66,978,149 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 NOT|acts_upstream_of_or_within ISO MGI:2154690 (PMID:16636061) RGD PMID:16636061 NCBI chr 6:21,093,927...21,103,091 JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP 2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:18637154 RGD:4778755 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Prkcb protein kinase C, beta IEP RGD PMID:16797713 RGD:5131886 NCBI chr 1:186,263,397...186,594,743 JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP RGD PMID:11222880 RGD:4892000 NCBI chr 6:27,178,089...27,217,588 JBrowse link
G Star steroidogenic acute regulatory protein IEP 2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:18637154 RGD:4778755 NCBI chr16:72,969,824...72,974,447 JBrowse link
dibenzo-p-dioxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA
IMP
2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:15812643 PMID:12914780 RGD:2306662, RGD:2306673 NCBI chr 8:66,991,940...66,998,014 JBrowse link

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  biological_process 20534
    cellular process 19523
      metabolic process 12157
        small molecule metabolic process 1918
          dibenzo-p-dioxin metabolic process 10
            dibenzo-p-dioxin catabolic process 1
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