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ONTOLOGY REPORT - ANNOTATIONS

Term:alcohol dehydrogenase [NAD(P)+] activity
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Accession:GO:0018455 term browser browse the term
Definition:Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde or ketone + NAD(P)H + H+.
Synonyms:related_synonym: alcohol:NAD(P)+ oxidoreductase activity;   aldehyde reductase (NADPH/NADH)

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alcohol dehydrogenase [NAD(P)+] activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHRS4 dehydrogenase/reductase 4 enables IEA Ensembl GO_REF:0000107 NCBI chr29:24,170,090...24,185,509
Ensembl chr29:24,169,818...24,185,634 		JBrowse link
alcohol dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA UniProt
Ensembl		 GO_REF:0000107 GO_REF:0000117 NCBI chr 7:47,226,787...47,248,518
Ensembl chr 7:47,226,191...47,248,234 		JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide enables IEA
ISO		 UniProt
RHEA
Ensembl
RGD		 PMID:18207224 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 RGD:5129089 NCBI chr 7:47,190,031...47,211,670
Ensembl chr 7:47,190,294...47,211,651 		JBrowse link
G ADH6 alcohol dehydrogenase 6 (class V) enables IEA Ensembl GO_REF:0000107 NCBI chr 7:47,294,074...47,309,771
Ensembl chr 7:47,291,221...47,309,102 		JBrowse link
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide enables ISO
IEA		 RGD
Ensembl		 PMID:10829036 GO_REF:0000107 RGD:631904 NCBI chr 7:47,571,477...47,592,502
Ensembl chr 7:47,571,564...47,590,593 		JBrowse link
G ADHFE1 alcohol dehydrogenase iron containing 1 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 8:62,300,884...62,337,886
Ensembl chr 8:62,300,979...62,338,096 		JBrowse link
G DHRS9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr10:54,611,792...54,641,037
Ensembl chr10:54,614,559...54,641,877 		JBrowse link
G LOC103236010 alcohol dehydrogenase 1C enables IEA UniProt
Ensembl		 GO_REF:0000107 GO_REF:0000117 NCBI chr 7:47,480,809...47,526,508 JBrowse link
G LOC119620184 alcohol dehydrogenase class-3-like enables IEA UniProt
RHEA
Ensembl		 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116
alcohol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1A1 aldo-keto reductase family 1 member A1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 NCBI chr20:87,228,348...87,245,511
Ensembl chr20:87,228,189...87,245,466 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 enables IEA Ensembl GO_REF:0000107 NCBI chr16:18,302,145...18,312,768
Ensembl chr16:18,302,142...18,312,756 		JBrowse link
G RDH14 retinol dehydrogenase 14 enables IEA Ensembl GO_REF:0000107 NCBI chr14:89,128,850...89,134,879
Ensembl chr14:89,128,828...89,135,033 		JBrowse link
aldo-keto reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 enables IEA Ensembl GO_REF:0000107 Ensembl chr 9:5,248,610...5,263,474 JBrowse link
G KCNAB1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr15:34,223,250...34,467,924
Ensembl chr15:34,221,890...34,468,001 		JBrowse link
G KCNAB2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr20:125,636,352...125,743,821
Ensembl chr20:125,638,962...125,708,768 		JBrowse link
G KCNAB3 potassium voltage-gated channel subfamily A regulatory beta subunit 3 enables IEA TreeGrafter GO_REF:0000118 Ensembl chr16:7,311,185...7,317,855 JBrowse link
G MIOX myo-inositol oxygenase enables IEA Ensembl GO_REF:0000107 NCBI chr19:32,953,268...32,960,123
Ensembl chr19:32,957,256...32,961,023 		JBrowse link
aldose reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA Ensembl GO_REF:0000107 NCBI chr 7:47,226,787...47,248,518
Ensembl chr 7:47,226,191...47,248,234 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:87,228,348...87,245,511
Ensembl chr20:87,228,189...87,245,466 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 enables IEA Ensembl GO_REF:0000107 Ensembl chr 9:5,248,610...5,263,474 JBrowse link
G LOC103225480 aflatoxin B1 aldehyde reductase member 2 ISO RGD PMID:12071861 RGD:625492 NCBI chr20:113,234,257...113,242,445 JBrowse link
G LOC103226928 aldo-keto reductase family 1 member B1 enables IEA Ensembl GO_REF:0000107 NCBI chr21:103,060,018...103,076,844
Ensembl chr21:103,059,991...103,077,341 		JBrowse link
all-trans-retinol dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide enables IEA Ensembl GO_REF:0000107 NCBI chr 7:47,226,787...47,248,518
Ensembl chr 7:47,226,191...47,248,234 		JBrowse link
G ADH6 alcohol dehydrogenase 6 (class V) enables IEA TreeGrafter GO_REF:0000118 NCBI chr 7:47,294,074...47,309,771
Ensembl chr 7:47,291,221...47,309,102 		JBrowse link
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide enables IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:47,571,477...47,592,502
Ensembl chr 7:47,571,564...47,590,593 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 NOT|enables ISO (PMID:12732097) UniProt PMID:12732097 NCBI chr20:87,228,348...87,245,511
Ensembl chr20:87,228,189...87,245,466 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 enables IEA Ensembl GO_REF:0000107 Ensembl chr 9:5,248,610...5,263,474 JBrowse link
G DHRS3 dehydrogenase/reductase 3 enables IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:119,183,453...119,236,953
Ensembl chr20:119,184,996...119,237,015 		JBrowse link
G DHRS7C dehydrogenase/reductase 7C enables IEA Ensembl GO_REF:0000107 NCBI chr16:9,111,538...9,132,553
Ensembl chr16:9,111,957...9,132,355 		JBrowse link
G DHRS9 dehydrogenase/reductase 9 enables ISO
IEA		 RGD
Ensembl		 PMID:12390888 GO_REF:0000107 RGD:633755 NCBI chr10:54,611,792...54,641,037
Ensembl chr10:54,614,559...54,641,877 		JBrowse link
G HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 enables IEA Ensembl GO_REF:0000107 NCBI chr11:52,710,903...52,736,645
Ensembl chr11:52,710,758...52,736,629 		JBrowse link
G LOC103236010 alcohol dehydrogenase 1C enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:47,480,809...47,526,508 JBrowse link
G LOC103236829 short chain dehydrogenase/reductase family 16C member 5 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:52,330,362...52,365,253
Ensembl chr 8:52,330,731...52,351,250 		JBrowse link
G RDH10 retinol dehydrogenase 10 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:68,903,665...68,933,536
Ensembl chr 8:68,904,352...68,933,792 		JBrowse link
G RDH12 retinol dehydrogenase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr24:44,957,854...44,971,855
Ensembl chr24:44,959,921...44,971,836 		JBrowse link
G RDH16 retinol dehydrogenase 16 enables ISO
IEA		 RGD
Ensembl		 PMID:7499345 GO_REF:0000107 RGD:1299624 NCBI chr11:52,826,447...52,854,731
Ensembl chr11:52,848,488...52,854,167 		JBrowse link
G RDH5 retinol dehydrogenase 5 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:51,667,461...51,672,386
Ensembl chr11:51,668,803...51,672,192 		JBrowse link
G RDH8 retinol dehydrogenase 8 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:9,096,680...9,102,770 JBrowse link
G SDR9C7 short chain dehydrogenase/reductase family 9C member 7 enables IEA Ensembl GO_REF:0000107 NCBI chr11:52,819,041...52,831,778
Ensembl chr11:52,819,957...52,830,249 		JBrowse link
all-trans-retinol dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHRS3 dehydrogenase/reductase 3 enables ISO (PMID:24005908) MGI PMID:24005908 NCBI chr20:119,183,453...119,236,953
Ensembl chr20:119,184,996...119,237,015 		JBrowse link
G DHRS4 dehydrogenase/reductase 4 enables ISO (PMID:12604222) UniProt PMID:12604222 NCBI chr29:24,170,090...24,185,509
Ensembl chr29:24,169,818...24,185,634 		JBrowse link
G DHRS7 dehydrogenase/reductase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr24:37,368,792...37,389,433
Ensembl chr24:37,368,982...37,389,403 		JBrowse link
G RDH10 retinol dehydrogenase 10 enables IEA UniProt GO_REF:0000003 NCBI chr 8:68,903,665...68,933,536
Ensembl chr 8:68,904,352...68,933,792 		JBrowse link
G RDH11 retinol dehydrogenase 11 enables IEA Ensembl GO_REF:0000107 NCBI chr24:44,911,830...44,932,632
Ensembl chr24:44,909,001...44,932,611 		JBrowse link
G RDH12 retinol dehydrogenase 12 enables IEA Ensembl GO_REF:0000107 NCBI chr24:44,957,854...44,971,855
Ensembl chr24:44,959,921...44,971,836 		JBrowse link
G RDH13 retinol dehydrogenase 13 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:47,634,909...47,652,829
Ensembl chr 6:47,636,094...47,652,772 		JBrowse link
G RDH14 retinol dehydrogenase 14 enables IEA Ensembl GO_REF:0000107 NCBI chr14:89,128,850...89,134,879
Ensembl chr14:89,128,828...89,135,033 		JBrowse link
carbonyl reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBR1 carbonyl reductase 1 enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 Ensembl chr 2:80,096,955...80,102,721 JBrowse link
G CBR3 carbonyl reductase 3 enables ISO
IEA		 RGD
Ensembl
TreeGrafter
UniProt		 PMID:18983987 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:2316293 NCBI chr 2:80,158,842...80,164,208
Ensembl chr 2:80,158,806...80,164,248 		JBrowse link
G DCXR dicarbonyl and L-xylulose reductase enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:73,923,170...73,925,025
Ensembl chr16:73,919,463...73,925,277 		JBrowse link
G DHRS1 dehydrogenase/reductase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr24:1,273,717...1,282,761
Ensembl chr24:1,273,659...1,282,812 		JBrowse link
G DHRS2 dehydrogenase/reductase 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:24,015,535...24,022,897
Ensembl chr29:24,016,071...24,022,500 		JBrowse link
G DHRS4 dehydrogenase/reductase 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:24,170,090...24,185,509
Ensembl chr29:24,169,818...24,185,634 		JBrowse link
G DHRS7 dehydrogenase/reductase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr24:37,368,792...37,389,433
Ensembl chr24:37,368,982...37,389,403 		JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 enables ISO (PMID:18449627), (PMID:1921984) UniProt PMID:1921984 PMID:18449627 NCBI chr 2:80,096,743...80,099,982 JBrowse link
L-iditol 2-dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103221304 sorbitol dehydrogenase-like enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr15:22,411,218...22,413,251 JBrowse link
G SORD sorbitol dehydrogenase enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr26:38,129,236...38,173,867
Ensembl chr26:38,126,911...38,155,381 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18124
    catalytic activity 5456
      oxidoreductase activity 716
        oxidoreductase activity, acting on CH-OH group of donors 127
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 119
            alcohol dehydrogenase [NAD(P)+] activity 40
              3-methylbutanal reductase [NAD(P)H] activity + 0
              alcohol dehydrogenase (NAD+) activity + 22
              aldo-keto reductase (NADPH) activity + 24
paths to the root